Turtlehead + Metoclopramide Hydrochloride
Metoclopramide Hydrochloride brand name: Gimoti.
We found no known interaction between Turtlehead and Metoclopramide Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Turtlehead and Metoclopramide Hydrochloride
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Metoclopramide Hydrochloride and Turtlehead in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Turtlehead at all — not against Metoclopramide Hydrochloride, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Turtlehead safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Metoclopramide Hydrochloride
This page covers Turtlehead only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Metoclopramide Hydrochloride page lists 135 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: 1,4-butanediol (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major), Kava (major) and L-tryptophan (major).
By severity: 7 major · 114 moderate · 14 minor.
From our pharmacist’s overview on the Metoclopramide Hydrochloride page
“Metoclopramide (Gimoti, also sold as Reglan) calms nausea and speeds a slow stomach by acting on the brain, and that is exactly where most of these 135 supplements and herbs collide with it. This is a list to treat with genuine care.”
Reviewed by 2 · Jul 18, 2026
Where Turtlehead and Metoclopramide Hydrochloride Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#469 of 1,452 supplements looked up here in the last 7 days
#1,191 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Turtlehead is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Turtlehead reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Turtlehead and Metoclopramide Hydrochloride records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Turtlehead
What is Turtlehead?
- Constipation and as a mild laxative
- Digestive upset and poor appetite
- Liver and gallbladder complaints (traditional)
- Skin irritation applied topically (traditional)
- General "bitter tonic" for digestion
Turtlehead (Chelone glabra) is a North American wildflower used in traditional herbal medicine, mainly as a bitter digestive tonic and mild laxative. There is very little modern scientific evidence to confirm any health benefit, and its safety has not been well studied. Talk with a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.
Chelone glabra · Plantaginaceae · Aerial parts (leaves and flowering tops); occasionally the root · Dried herb, tea (infusion), tincture, liquid extract
An interaction check asks whether these two react with each other — it does not ask whether Turtlehead is a good idea for someone in your situation. Here is what our Turtlehead record says about it on its own.
Turtlehead: dosing
There is no established, scientifically tested dose for turtlehead. Traditional use involved teas made from the dried herb or alcohol-based tinctures, but standardized dosing has not been set.If you choose to use a commercial product, follow the directions on the label and do not exceed them.
From our Turtlehead monograph — the full record covers uses, side effects and every documented interaction.
About Metoclopramide Nasal Spray
What Is Metoclopramide Nasal Spray Used For?
Brand name: Gimoti
Gimoti (metoclopramide nasal spray) is approved for adults with acute and recurrent diabetic gastroparesis — a condition where diabetes damages the nerves controlling stomach emptying, causing nausea, vomiting, and bloating. It works to relieve those symptoms by helping the stomach empty more normally.
Gimoti is not recommended for children, or for adults with moderate to severe kidney or liver disease. It is also not recommended for adults taking strong CYP2D6 inhibitor medications (certain antidepressants and other drugs that slow how the body breaks down metoclopramide).
Most-Reported Side Effects for Metoclopramide Hydrochloride
From FAERS, the FDA’s public side-effect reporting system (76,710 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Turtlehead
Browse every other medication we’ve checked against Turtlehead — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Turtlehead against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Metoprolol ›
- Aspirin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Acetaminophen ›
- Escitalopram ›
- Tadalafil ›
- Clopidogrel ›
- Abemaciclib ›
- Atorvastatin ›
- Docusate ›
- Valacyclovir ›
- Hydroxyurea ›
- Ibuprofen ›
- Methamphetamine ›
- Tirzepatide ›
- Semaglutide ›
- Warfarin Sodium ›
- Sumatriptan ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Metformin ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Bendamustine ›
- Amitriptyline ›
- Acyclovir ›
- Methotrexate ›
- Doxycycline ›
- Fluoxetine ›
- Amphetamine ›
- Lamotrigine ›
- Pregabalin ›
- Acetaminophen, Codeine ›
- Azithromycin ›
- Gabapentin ›
- Dextroamphetamine ›
- Isotretinoin ›
- Clonazepam ›
- Methylene Blue ›
- Omeprazole ›
- Amlodipine Besylate ›
- Quetiapine ›
- Letrozole ›
- Duloxetine ›
- Naproxen ›
- Buspirone ›
- Citalopram ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Turtlehead list.
Turtlehead References
The 2 sources that drive our Turtlehead monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Turtlehead is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- Herbs at a Glance — NIH National Center for Complementary and Integrative Health Source
- Herbs and Supplements — MedlinePlus (U.S. National Library of Medicine) Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Turtlehead and Metoclopramide Hydrochloride Together: Common Questions
Is it safe to take Turtlehead with Metoclopramide Hydrochloride?
Does Metoclopramide Hydrochloride interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.