Drug & supplement interaction

Verbena + Encorafenib

Encorafenib brand name: Braftovi.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Verbena and Encorafenib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Verbena and Encorafenib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Encorafenib and Verbena in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Verbena at all — not against Encorafenib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Verbena safety at a glance

Verbena overall Use caution Likely tolerated by many adults in food and tea amounts, but human safety data are limited.
Pregnancy Avoid Traditionally said to affect the uterus, so avoid during pregnancy.
Breastfeeding Avoid Not enough safety information, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Encorafenib and Verbena? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Verbena and Encorafenib May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Verbena

    “Orally, verbena is well tolerated when used orally in amounts commonly found in foods. When used in medicinal amounts and in combination with other herbs, adverse effects have included gastrointestinal adverse effects and allergic skin reactions.

    Topically, verbena can cause contact dermatitis.”

    Verbena · Natural Medicines adverse-effect record, reported in dermatitis.

    4 sources cited
    1. 4912. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
    2. 374. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
    3. 379. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
    4. 13431. Del Pozo MD, Gastaminza G, Navarro JA, et al. Allergic contact dermatitis from Verbena officinalis L. Contact Dermatitis 1994;31:200-1.

    “Orally, verbena in combination with other herbs can cause allergic skin reactions. Topically, verbena can cause contact dermatitis.”

    Verbena · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 374. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
    2. 379. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
    3. 13431. Del Pozo MD, Gastaminza G, Navarro JA, et al. Allergic contact dermatitis from Verbena officinalis L. Contact Dermatitis 1994;31:200-1.

    Encorafenib

    Listed in the ADVERSE REACTIONS section of the FDA label for Encorafenib. Read the label on DailyMed ›

Effects for Encorafenib come from the ADVERSE REACTIONS section of its FDA label; effects for Verbena come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Verbena or Encorafenib

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Verbena or Encorafenib, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Encorafenib

This page covers Verbena only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Encorafenib page lists 151 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 104 moderate · 39 minor.

From our pharmacist’s overview on the Encorafenib page

“Grapefruit is the first thing I would take off the table for anyone on encorafenib (Braftovi), a targeted cancer medicine, because it blocks the enzyme (CYP3A4) that clears the drug, pushing levels and side effects higher. St.”

Reviewed by 2 · Jul 18, 2026

Open the Encorafenib interaction page

One more smart check

Taking Verbena as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Verbena, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Verbena. Even though Verbena itself has no known interaction with Encorafenib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Verbena and Encorafenib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Verbena
Steady interest

#753 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Encorafenib
Steady interest

#1,826 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Verbena reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Verbena and Encorafenib records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Verbena

What is Verbena?

  • Anxiety and stress
  • Sleep and relaxation
  • Digestive upset
  • Sore throat and oral health
  • Minor inflammation

Verbena (Verbena officinalis), also called vervain, is a traditional herb people use for relaxation, sleep, and minor digestive complaints. Solid human research is limited, so its benefits remain largely unproven. It is best to use cautiously and check with your pharmacist or doctor first, especially if you are pregnant or breastfeeding.

Verbena officinalis · Verbenaceae · Aerial parts (leaves, stems, and flowers) · Tea, tincture, capsules, liquid extract, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Verbena is a good idea for someone in your situation. Here is what our Verbena record says about it on its own.

Verbena: dosing

There is no official or standardized dose for verbena. Traditional use most often involves a tea made from the dried herb, but the amount of active compounds can vary widely between products.The safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Verbena monograph — the full record covers uses, side effects and every documented interaction.

Read the full Verbena monograph & all interactions
Medication

About Encorafenib

What Is Encorafenib Used For?

Brand name: Braftovi

Braftovi is used to treat cancers that have a specific change (mutation) in a gene called BRAF — specifically the V600E or V600K mutation, which must be confirmed by an FDA-authorized test before starting treatment. It is always used in combination with other medicines, never alone as standard therapy.

Braftovi (in combination with binimetinib) treats unresectable or metastatic melanoma with a BRAF V600E or V600K mutation. For metastatic colorectal cancer (mCRC) with a BRAF V600E mutation, Braftovi is used either with cetuximab and fluorouracil-based chemotherapy, or with cetuximab alone after prior therapy. Braftovi (in combination with binimetinib) also treats metastatic non-small cell lung cancer (NSCLC) with a BRAF V600E mutation.

Most-Reported Side Effects for Encorafenib

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 842 reports
Fatigue 770 reports
Diarrhea 634 reports
Fever 599 reports
Neoplasm progression 552 reports
See full Encorafenib drug information
Keep checking

Other Drugs & Verbena

Browse every other medication we’ve checked against Verbena — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Verbena References

The 6 references that drive our Verbena monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  4. Del Pozo MD, Gastaminza G, Navarro JA, et al. Allergic contact dermatitis from Verbena officinalis L. Contact Dermatitis 1994;31:200-1.
  5. Peric A, Kovacevic SV, Gacesa D, Peric AV. Efficacy and safety of combined treatment of acute rhinosinusitis by herbal medicinal product Sinupret and mometasone furoate nasal spray. ENT Updates 2017;7(2):68-74. DOI
  6. Grawish ME, Anees MM, Elsabaa HM, Abdel-Raziq MS, Zedan W. Short-term effects of Verbena officinalis Linn decoction on patients suffering from chronic generalized gingivitis: Double-blind randomized controlled multicenter clinical trial. Quintessence Int.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Verbena and Encorafenib Together: Common Questions

Is it safe to take Verbena with Encorafenib?
We do not list a known interaction between Verbena and Encorafenib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Verbena and Encorafenib have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Encorafenib interact with any supplements?
Yes. Encorafenib has documented interactions with 151 supplements in our database — Verbena is not one of them. The Encorafenib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Encorafenib and Verbena?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.