Does Lemon Verbena Interact With Coreg (Carvedilol)?

In our latest question and answer, our pharmacist discusses whether or not there is an interaction between lemon verbena and Coreg.

Question

Can I drink lemon verbena tea while I am also taking carvedilol for blood pressure?

Asked by Anna On Feb 05, 2024

Answered by
Medical Content Reviewed By HelloPharmacist Staff

Published Feb 18, 2024
Last updated Apr 12, 2024

Key points

  • Lemon verbena is generally considered safe, with mild sedation being the most common side effect reported in studies.
  • There is no known drug interaction between lemon verbena and Coreg (carvedilol).

Answer

Thank you for your inquiry!

Lemon verbena is generally regarded as safe with very few reported interactions with other drugs and there is currently no known interaction between it and Coreg (carvedilol).

Our drug-herbal interaction checker shows only a potential interaction between lemon verbena with drugs in the benzodiazepine class, primarily due to the risk of additive sedative effects (you can find more information on our lemon verbena-diazepam page).

Lemon Verbena Appears To Be Relatively Free Of Significant Side Effects

Lemon verbena (Aloysia citrodora) is a shrub native to South America, known for its fragrant lemon scent (although it is not botanically related to lemon (Citrus limon)). Research indicates that lemon verbena is high in polyphenols, including flavone diglucuronides and verbascoside, a phenylpropanoid glycoside. The essential oil of lemon verbena leaf contains caryophyllene, limonene, and linalool.

While lemon verbena hasn't been extensively studied, clinical research suggests it is generally well tolerated when ingested as a supplement or as a beverage (such as tea), with mild sedation being the most common side effect reported in studies.

Studies evaluating lemon verbena's effects on exercise-induced muscle damage, such as this study, did not find any evidence indicating a significant effect on blood pressure or a mechanism of action that would suggest an interaction with Coreg or any other blood pressure medication.

Although there are a few small studies suggesting that lemon verbena, when combined with other herbals like hibiscus, may slightly lower blood pressure, substantive evidence supporting a significant interaction with blood pressure medication or a substantial risk of additive blood pressure lowering when combined with a blood pressure medication is lacking.

While more studies are needed to fully understand lemon verbena's effects, it appears unlikely that it interacts with blood pressure medication or significantly lowers blood pressure when used alone or in combination with a blood pressure medication.

As always, be sure to let your doctor know about all the medications and supplements you are taking so you can be appropriately monitored.

Final Thoughts

Thank you for reaching out, and please don't hesitate to contact us again with any further questions!

References

  • Anxiolytic Effect and Improved Sleep Quality in Individuals Taking Lippia citriodora Extract, PubMed
  • Effects of lemon verbena extract (Recoverben┬«) supplementation on muscle strength and recovery after exhaustive exercise: a randomized, placebo-controlled trial, PubMed
  • Evaluation of the Efficacy of Supplementation with Planox┬« Lemon Verbena Extract in Improving Oxidative Stress and Muscle Damage: A Randomized Double-Blind Controlled Trial, PubMed
  • A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of a Polyphenolic Extract ( Hibiscus sabdariffa and Lippia citriodora) for Reducing Blood Pressure in Prehypertensive and Type 1 Hypertensive Subjects, PubMed

About the Pharmacist

Dr. Brian Staiger, PharmD

Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! Dr. Brian Staiger also has herbalist training and educational certificates in the field of medical ethnobotany. Feel free to send him an email at [email protected]! You can also connect with Dr. Brian Staiger on LinkedIn.

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