Does Lemon Verbena Interact With Coreg (Carvedilol)?

Answer

Thank you for your inquiry!

Lemon verbena is generally regarded as safe with very few reported interactions with other drugs and there is currently no known interaction between it and Coreg (carvedilol).

Our drug-herbal interaction checker shows only a potential interaction between lemon verbena with drugs in the benzodiazepine class, primarily due to the risk of additive sedative effects (you can find more information on our lemon verbena-diazepam page).

Lemon Verbena Appears To Be Relatively Free Of Significant Side Effects

Lemon verbena (Aloysia citrodora) is a shrub native to South America, known for its fragrant lemon scent (although it is not botanically related to lemon (Citrus limon)). Research indicates that lemon verbena is high in polyphenols, including flavone diglucuronides and verbascoside, a phenylpropanoid glycoside. The essential oil of lemon verbena leaf contains caryophyllene, limonene, and linalool.

While lemon verbena hasn't been extensively studied, clinical research suggests it is generally well tolerated when ingested as a supplement or as a beverage (such as tea), with mild sedation being the most common side effect reported in studies.

Studies evaluating lemon verbena's effects on exercise-induced muscle damage, such as this study, did not find any evidence indicating a significant effect on blood pressure or a mechanism of action that would suggest an interaction with Coreg or any other blood pressure medication.

Although there are a few small studies suggesting that lemon verbena, when combined with other herbals like hibiscus, may slightly lower blood pressure, substantive evidence supporting a significant interaction with blood pressure medication or a substantial risk of additive blood pressure lowering when combined with a blood pressure medication is lacking.

While more studies are needed to fully understand lemon verbena's effects, it appears unlikely that it interacts with blood pressure medication or significantly lowers blood pressure when used alone or in combination with a blood pressure medication.

As always, be sure to let your doctor know about all the medications and supplements you are taking so you can be appropriately monitored.

Final Thoughts

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