Can You Cut Lisinopril Tablets In Half?
In our latest question and answer, the pharmacist discusses whether or not lisinopril tablets can safely be cut in half.

Question
Hi, I am taking lisinopril 40mg and my blood pressure is good. My doctor is switching me to 20mg but I have plenty of 40mg on hand. Can I just split these lisinopril 40mg tablets in half?

Answered by Dr. Brian Staiger, PharmD
Medical Content Reviewed By HelloPharmacist
Staff
Last updated Apr 15, 2025
Key points
- Lisinopril tablets can safely be cut in half. They can also be crushed and sprinkled onto food.
Answer
Yes, lisinopril tablets can safely be cut in half. In fact, many lisinopril tablets have a score mark down the middle to make cutting them easier. However, even if they don't have a score mark, they can still be split. Just make sure to use a sharp knife or dedicated pill splitter to ensure an even cut down the middle.
All strengths of lisinopril tablets can be cut in half, so this includes:
- Lisinopril 2.5 mg
- Lisinopril 5mg
- Lisinopril 10mg
- Lisinopril 20mg
- Lisinopril 30mg
- Lisinopril 40mg
In your case, splitting the 40mg tablets you have to attain a dose of 20mg makes sense. I just recommend that you only cut one tablet at a time, and not all of them at once to store for later use since splitting tablets can sometimes make the split pieces more susceptible to moisture damage.
Alternatives To Splitting
If you don't want to go through the hassle of splitting tablets, you do have some alternative options.
Lisinopril is available in a variety of strengths (listed above), so they may be available in what your doctor has changed your dose to.
The tablets can also safely be crushed and sprinkled on top of food.
Lastly, it is available in a liquid form (Qbrelis 1mg/mL Solution), but currently, it is only available as a brand name, so it may not be covered by your insurance.
Final Words
I hope you found this helpful!
Reach back out anytime.
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Dr. Brian Staiger, PharmD
- 9715 views