Drug & supplement interaction

Verbena + Risedronate

Risedronate brand name: Actonel DR.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Verbena and Risedronate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Verbena and Risedronate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Risedronate and Verbena in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Verbena at all — not against Risedronate, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Verbena safety at a glance

Verbena overall Use caution Likely tolerated by many adults in food and tea amounts, but human safety data are limited.
Pregnancy Avoid Traditionally said to affect the uterus, so avoid during pregnancy.
Breastfeeding Avoid Not enough safety information, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Risedronate and Verbena? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Verbena and Risedronate May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Verbena

    “Orally, verbena is well tolerated when used orally in amounts commonly found in foods. When used in medicinal amounts and in combination with other herbs, adverse effects have included gastrointestinal adverse effects and allergic skin reactions.

    Topically, verbena can cause contact dermatitis.”

    Verbena · Natural Medicines adverse-effect record, reported in dermatitis.

    4 sources cited
    1. 4912. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
    2. 374. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
    3. 379. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
    4. 13431. Del Pozo MD, Gastaminza G, Navarro JA, et al. Allergic contact dermatitis from Verbena officinalis L. Contact Dermatitis 1994;31:200-1.

    “Orally, verbena in combination with other herbs can cause allergic skin reactions. Topically, verbena can cause contact dermatitis.”

    Verbena · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 374. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
    2. 379. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
    3. 13431. Del Pozo MD, Gastaminza G, Navarro JA, et al. Allergic contact dermatitis from Verbena officinalis L. Contact Dermatitis 1994;31:200-1.

    Risedronate

    Listed in the ADVERSE REACTIONS section of the FDA label for Risedronate. Read the label on DailyMed ›

Effects for Risedronate come from the ADVERSE REACTIONS section of its FDA label; effects for Verbena come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Verbena or Risedronate

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Verbena or Risedronate, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Risedronate

This page covers Verbena only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Risedronate page lists 23 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Calcium (moderate), Coffee Charcoal (moderate), Dolomite (moderate) and European Mandrake (moderate).

By severity: 1 major · 13 moderate · 9 minor.

From our pharmacist’s overview on the Risedronate page

“Risedronate (Actonel DR) is an osteoporosis medicine with an Achilles heel, poor absorption. Only a small fraction of each dose ever reaches the bone, and the 23 supplements on this page deserve genuine wariness because nearly all of them attack that weak point by binding or blunting the drug in the gut.”

Reviewed by 2 · Jul 18, 2026

Open the Risedronate interaction page

One more smart check

Taking Verbena as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Verbena, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Verbena. Even though Verbena itself has no known interaction with Risedronate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Verbena and Risedronate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Verbena
Steady interest

#975 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Risedronate
Steady interest

#2,423 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Verbena reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Verbena and Risedronate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Verbena

What is Verbena?

  • Anxiety and stress
  • Sleep and relaxation
  • Digestive upset
  • Sore throat and oral health
  • Minor inflammation

Verbena (Verbena officinalis), also called vervain, is a traditional herb people use for relaxation, sleep, and minor digestive complaints. Solid human research is limited, so its benefits remain largely unproven. It is best to use cautiously and check with your pharmacist or doctor first, especially if you are pregnant or breastfeeding.

Verbena officinalis · Verbenaceae · Aerial parts (leaves, stems, and flowers) · Tea, tincture, capsules, liquid extract, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Verbena is a good idea for someone in your situation. Here is what our Verbena record says about it on its own.

Verbena: dosing

There is no official or standardized dose for verbena. Traditional use most often involves a tea made from the dried herb, but the amount of active compounds can vary widely between products.The safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Verbena monograph — the full record covers uses, side effects and every documented interaction.

Read the full Verbena monograph & all interactions
Medication

About Risedronate

What Is Risedronate Used For?

Brand name: Actonel DR

Risedronate sodium tablets are used to treat and prevent osteoporosis in postmenopausal women, treat osteoporosis in men to increase bone mass, and treat and prevent osteoporosis caused by long-term steroid (glucocorticoid) use in both men and women. They are also used to treat Paget's disease of bone — a condition where bones break down and rebuild abnormally, becoming enlarged and weakened.

Risedronate sodium delayed-release tablets (brands Atelvia and Risedronate Sodium delayed-release) are approved specifically for the treatment of postmenopausal osteoporosis only — not for the other uses listed above.

See full Risedronate drug information
Keep checking

Other Drugs & Verbena

Browse every other medication we’ve checked against Verbena — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Verbena References

The 6 references that drive our Verbena monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  4. Del Pozo MD, Gastaminza G, Navarro JA, et al. Allergic contact dermatitis from Verbena officinalis L. Contact Dermatitis 1994;31:200-1.
  5. Peric A, Kovacevic SV, Gacesa D, Peric AV. Efficacy and safety of combined treatment of acute rhinosinusitis by herbal medicinal product Sinupret and mometasone furoate nasal spray. ENT Updates 2017;7(2):68-74. DOI
  6. Grawish ME, Anees MM, Elsabaa HM, Abdel-Raziq MS, Zedan W. Short-term effects of Verbena officinalis Linn decoction on patients suffering from chronic generalized gingivitis: Double-blind randomized controlled multicenter clinical trial. Quintessence Int.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Verbena and Risedronate Together: Common Questions

Is it safe to take Verbena with Risedronate?
We do not list a known interaction between Verbena and Risedronate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Verbena and Risedronate have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Risedronate interact with any supplements?
Yes. Risedronate has documented interactions with 23 supplements in our database — Verbena is not one of them. The Risedronate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Risedronate and Verbena?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.