Drug & supplement interaction

White Dead Nettle Flower + Lonafarnib

Lonafarnib brand name: Zokinvy.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between White Dead Nettle Flower and Lonafarnib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Lonafarnib states a food rule worth keeping to.

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Interaction report

White Dead Nettle Flower and Lonafarnib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lonafarnib and White Dead Nettle Flower in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for White Dead Nettle Flower at all — not against Lonafarnib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

White Dead Nettle Flower safety at a glance

White Dead Nettle... overall Use caution Traditionally considered mild, but human safety and effectiveness data are limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoid use to be cautious.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lonafarnib and White Dead Nettle Flower? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Lonafarnib’s Own FDA Label Lists

This is not an interaction — none of it involves White Dead Nettle Flower. These are the most notable effects listed in the ADVERSE REACTIONS section of Lonafarnib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Dehydration Worth acting on
  • High potassium Worth acting on
  • Low sodium Worth acting on
  • Low potassium Worth acting on
  • High blood sugar Worth acting on
  • Low mood Worth acting on
  • Raised blood pressure Worth acting on
  • A low white blood cell count Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on

Showing the 10 most notable of 29 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Lonafarnib. Read the label on DailyMed › White Dead Nettle Flower’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no White Dead Nettle Flower side to compare — that is a limit of the record, not a statement that White Dead Nettle Flower has no side effects.

How to take them

Some Lonafarnib Products Have a Food Rule — White Dead Nettle Flower Should Not Break It

At least one FDA label for a product containing Lonafarnib says to take it with food. If you take White Dead Nettle Flower on an empty stomach out of habit, keep them separate — and take Lonafarnib with a meal where the label says to.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Lonafarnib products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

If a dose is missed, take the dose as soon as possible with food, up to 8 hours prior to the next scheduled dose.

From the Dosage and Administration section of the FDA label we read for Lonafarnib — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Lonafarnib

This page covers White Dead Nettle Flower only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lonafarnib page lists 160 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Grapefruit (major), Siberian Cocklebur (major) and St. John's Wort (major).

By severity: 5 major · 115 moderate · 40 minor.

From our pharmacist’s overview on the Lonafarnib page

“If you or your child takes lonafarnib (Zokinvy) for progeria, treat supplements with real caution. Most of the 160 flagged ingredients cross paths with the CYP3A4 enzyme, the same one that handles lonafarnib, so the traffic runs both ways.”

Reviewed by 2 · Jul 18, 2026

Open the Lonafarnib interaction page

One more smart check

Taking White Dead Nettle Flower as Part of a Dietary Supplement Product? Check It for Interactions

We hold 3 real supplement products containing White Dead Nettle Flower, each one broken down to its full ingredient list — and combination products often carry several ingredients besides White Dead Nettle Flower. Even though White Dead Nettle Flower itself has no known interaction with Lonafarnib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where White Dead Nettle Flower and Lonafarnib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement White Dead Nettle Flower
Steady interest

#1,429 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Lonafarnib
Top half

#1,018 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every White Dead Nettle Flower reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The White Dead Nettle Flower and Lonafarnib records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About White Dead Nettle Flower

What is White Dead Nettle Flower?

  • Menstrual complaints
  • Mild digestive upset
  • Sore throat and coughs
  • Mild urinary or vaginal discomfort
  • Minor skin irritation (topical)

White dead nettle flower is a traditional European herbal remedy used for menstrual, digestive, and minor throat or skin complaints. High-quality human studies are largely lacking, so its benefits are not well proven. It is generally considered mild, but should be avoided in pregnancy and breastfeeding due to limited safety data, and you should check with a pharmacist before use.

Lamium album · Lamiaceae · Flowers (and sometimes the flowering tops) · Tea, tincture, dried herb, capsules, topical preparations

An interaction check asks whether these two react with each other — it does not ask whether White Dead Nettle Flower is a good idea for someone in your situation. Here is what our White Dead Nettle Flower record says about it on its own.

White Dead Nettle Flower: dosing

There is no officially established or standardized dose for white dead nettle flower. Traditional use typically involves a tea made from the dried flowers, but the amount varies between sources and products.Because a reliable, well-studied dose has not been set, the safest approach is to follow the directions on the product label.

From our White Dead Nettle Flower monograph — the full record covers uses, side effects and every documented interaction.

Read the full White Dead Nettle Flower monograph & all interactions
Medication

About Lonafarnib

What Is Lonafarnib Used For?

Brand name: Zokinvy

Zokinvy (lonafarnib) is approved for patients 12 months of age and older who have a body surface area of 0.39 m² or above. It is used to reduce the risk of mortality in Hutchinson-Gilford Progeria Syndrome (HGPS) — a rare, severe premature-aging disorder.

Zokinvy is also used to treat processing-deficient Progeroid Laminopathies — a related group of rare genetic conditions — specifically those caused by a heterozygous LMNA mutation with progerin-like protein buildup, or by homozygous or compound heterozygous ZMPSTE24 mutations. It is not indicated for other Progeroid Syndromes or processing-proficient Progeroid Laminopathies.

Most-Reported Side Effects for Lonafarnib

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 16 reports
Vomiting 12 reports
Headache 4 reports
Abdominal pain upper 3 reports
Asthenia 3 reports
See full Lonafarnib drug information
Keep checking

Other Drugs & White Dead Nettle Flower

Browse every other medication we’ve checked against White Dead Nettle Flower — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked White Dead Nettle Flower against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full White Dead Nettle Flower list.

See the full White Dead Nettle Flower interactions page
See every supplement checked against Lonafarnib, ranked by severity
Evidence & sources

White Dead Nettle Flower References

The 1 references that drive our White Dead Nettle Flower monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Shapira MY, Raphaelovich Y, Gilad L, et al. Treatment of atopic dermatitis with herbal combination of Eleutherococcus, Achillea millefolium, and Lamium album has no advantage over placebo: a double blind, placebo-controlled, randomized trial. J Am Acad De PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking White Dead Nettle Flower and Lonafarnib Together: Common Questions

Is it safe to take White Dead Nettle Flower with Lonafarnib?
We do not list a known interaction between White Dead Nettle Flower and Lonafarnib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take White Dead Nettle Flower and Lonafarnib at the same time of day?
At least one FDA label for a product containing Lonafarnib says to take it with food. If you take White Dead Nettle Flower on an empty stomach out of habit, keep them separate and take Lonafarnib with a meal where the label says to. Food instructions belong to the product rather than the ingredient — two Lonafarnib products can differ — so check the directions on your own box. This is about absorption, not an interaction.
Does Lonafarnib interact with any supplements?
Yes. Lonafarnib has documented interactions with 160 supplements in our database — White Dead Nettle Flower is not one of them. The Lonafarnib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

White Dead Nettle Flower monograph Uses, safety profile, and every drug interaction in one place Lonafarnib drug information The full plain-English guide to this medication Lonafarnib supplement interactions Every supplement checked against Lonafarnib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Lonafarnib and White Dead Nettle Flower?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.