White Mulberry - Adempas (Riociguat) Interaction
Herbal: White Mulberry
Also Known As: Morus alba, Chinese White Mulberry, Chin Sang, Common Mulberry, Egyptian Mulberry, Mora, Moral Blanco, Morera Blanca, Morin, Russian Mulberry, Silkworm Mulberry
Drug: Riociguat
Brand names:
Adempas
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
Jul 06, 2025
Interaction Details
There were no interactions found between Riociguat and White Mulberry. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Pharmacist Analysis
White mulberry is not known to have many clinically significant drug interactions.
While our drug-herb interaction checker does list potential interactions with antidiabetic drugs and drugs that are affected by a protein known as OCT2, it is generally thought these are clinically insignificant for most individuals as they are theoretical and have not been seen in humans.
Nevertheless, it is important to be cautious if you take any drug that our tool shows an interaction for.
- Dr. Brian Staiger, PharmDWhite Mulberry Overview
White mulberry (Morus alba) is a small to medium-sized deciduous tree that is native to China but has been introduced to many other regions of the world. It is widely cultivated for its sweet and juicy berries, which are a rich source of vitamins and minerals.
In traditional medicine, white mulberry fruit, leaves, and bark have been used for a variety of purposes, including treating high blood pressure, high cholesterol, and diabetes.
It is important to note that white mulberry and black mulberry are different species of the same genus (Morus). White mulberry (Morus alba) is the most common type of mulberry, and it is native to China. Black mulberry (Morus nigra) is native to western Asia and has a darker fruit.
Riociguat Overview
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Riociguat is used to treat pulmonary arterial hypertension (PAH; high blood pressure in the vessels that carry blood to the lungs). Riociguat is also used to treat chronic thromboembolic pulmonary hypertension (CTEPH; high blood pressure in the lung arteries caused by blood clots that narrow or block blood flow) in adults who cannot have surgery or for those treated with surgery who continue to have high lung blood pressure levels after surgery. Riociguat may improve the ability to exercise in people with PAH and CTEPH and may slow the worsening of symptoms in people with PAH. Riociguat is in a class of medications called soluble guanylate cyclase (sGC) stimulators. It works by relaxing the blood vessels in the lungs to allow blood to flow easily.
White Mulberry - More Interactions
White Mulberry interacts with 85 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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