Autogenic Training Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Autogenic Training interacts with medications. The heart of this page is the interaction list — every drug Autogenic Training is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Autogenic Training is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Autogenic Training against your medication
Add one medicationDrugs that interact with Autogenic Training
0 medications have a known interaction with Autogenic Training, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Autogenic Training. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Autogenic Training combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Autogenic Training: Uses, Safety & Side Effects
Autogenic training is a relaxation technique that uses self-directed phrases to create feelings of warmth, heaviness, and calm in the body. It is generally safe for most people and may help with stress, anxiety, and sleep, though the quality of research is mixed. It is best learned from a trained instructor and is not a replacement for medical treatment.
- Part used
- Not applicable (a mind-body relaxation technique, not a plant or supplement)
- Common forms
- Guided audio recordings, classes with a trained therapist, self-practice scripts, smartphone apps
- Stress and tension
- Anxiety
- Trouble sleeping
- High blood pressure
- Headaches and chronic pain
- Calming the body before stressful events
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
It is a low-risk mind-body practice for most healthy adults.
Insufficient reliable evidence available; however, there is no known reason to suspect an adverse effect.
Read the full pregnancy detailInsufficient reliable evidence available; however, there is no known reason to suspect an adverse effect.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Autogenic training is not an herb or a supplement. It is a structured relaxation technique that uses your own thoughts and gentle mental phrases to calm your body and mind. The name comes from words meaning "self-generated," because you guide the relaxation yourself.
The method was developed in the early 20th century by a German psychiatrist named Johannes Heinrich Schultz. It grew out of observations about hypnosis and deep relaxation. Today it is used as part of mind-body medicine, often alongside other approaches like meditation, breathing exercises, and biofeedback.
In a typical session, you sit or lie down in a quiet place and silently repeat phrases such as "my arms are heavy" or "my heartbeat is calm and steady." Over time, these phrases are meant to bring on feelings of warmth, heaviness, and deep calm. People practice it on their own, in classes, or with guided recordings and apps.
How it works
Autogenic training is thought to work by calming the body's stress response. When you feel stressed, your nervous system speeds up your heart rate, tightens muscles, and raises blood pressure. This is sometimes called the "fight-or-flight" response.
The repeated, focused phrases used in autogenic training are meant to shift the body toward a more relaxed state, often called the "rest-and-digest" response. This may slow the heart rate, ease muscle tension, and create a sense of warmth and heaviness in the limbs.
Because it is a learned mental skill rather than a drug, its effects depend a lot on regular practice. There are no active chemical compounds involved—the technique relies entirely on your attention and repeated practice.
Does Autogenic Training work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
For Autogenic Training, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.
Also studied for 26 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Angina
Preliminary clinical research in females with a type of angina called cardiac syndrome X shows that completing an 8-week autogenic training program reduces the severity and frequency of chest pain and improves quality of life when compared to control.
Insufficient Reliable Evidence To Rate Asthma
Preliminary clinical research shows that autogenic training might improve asthma symptoms and lung function and reduce the need for certain medications in patients with asthma.
Insufficient Reliable Evidence To Rate Athletic performance
Preliminary research shows that a training program including autogenic training and imagery training might improve gun shooting accuracy following intense exercise in biathletes. Other preliminary clinical research shows that autogenic training practiced three times weekly for 12 weeks does not reduce the number or severity of injuries in ballet dancers.
Insufficient Reliable Evidence To Rate Coronary heart disease (CHD)
Preliminary clinical research shows that autogenic training might improve cardiac function in some patients with coronary heart disease.
Insufficient Reliable Evidence To Rate Depression
Preliminary clinical research shows that autogenic training might reduce stress, "dysthymic-neurotic" states, and other depressive symptoms in patients with depression.
Insufficient Reliable Evidence To Rate Epilepsy
Preliminary clinical research shows that autogenic training might reduce seizure frequency and improve paroxysmal activity on EEG in patients with epilepsy.
Insufficient Reliable Evidence To Rate Fibromyalgia
Preliminary clinical research in patients with fibromyalgia shows that adding four 2-hour sessions of autogenic relaxation along with five 2-hour education sessions to usual care moderately reduces physical impairment, pain, fatigue, stiffness, anxiety, and depression compared to usual care only.
Insufficient Reliable Evidence To Rate Glaucoma
Preliminary clinical research shows that autogenic training might reduce long-term intraocular pressure in patients with glaucoma.
Insufficient Reliable Evidence To Rate HIV/AIDS
A small clinical study shows that autogenic training with progressive muscle relaxation might reduce anxiety, fatigue, depression, and confusion in patients with HIV when compared to baseline. Another small clinical study in this population shows that six 1-hour autogenic training sessions over 12 weeks, along with home practice and standard HIV care, does not improve quality of life or anxiety when compared to a control group receiving standard care alone. However, it may improve sleep in patients with sleep problems at baseline. The validity of this study is limited by a very high drop-out rate. A small clinical study in patients with HIV and depressive symptoms shows that six 1-hour autogenic training sessions over 12 weeks, along with home practice, might improve depressive symptoms and quality of life when compared to baseline. However, the lack of statistical comparison to the other study groups, which received progressive muscle relaxation or placebo, limits the validity of these findings.
Insufficient Reliable Evidence To Rate Hypertension
Preliminary clinical research shows that autogenic training might reduce blood pressure in some patients.
Insufficient Reliable Evidence To Rate Inflammatory bowel disease (IBD)
Preliminary clinical research shows that autogenic training might improve symptoms in patients with inflammatory bowel disease.
Insufficient Reliable Evidence To Rate Insomnia
A prospective cohort study has found that autogenic training is associated with improved sleep quality in patients with sleep problems. Small clinical studies in adults with insomnia also show that autogenic training improves sleep quality, sleep duration, and sleep efficiency when compared with a control group. Conversely, a small clinical study in university athletes with self-diagnosed sleep problems shows that adding autogenic training instructions to a recording of relaxing background music each evening for 14 days improves sleep quality and duration when compared with baseline, but not when compared to a control group using the background music alone.
Insufficient Reliable Evidence To Rate Irritable bowel syndrome (IBS)
Preliminary clinical research shows that autogenic training might improve symptoms in patients with irritable bowel syndrome.
Insufficient Reliable Evidence To Rate Labor pain
Insufficient Reliable Evidence To Rate Migraine headache
Preliminary clinical research in children aged 7-18 years shows that autogenic training alone or combined with biofeedback for 10 sessions over 7 weeks, reduces migraine headache frequency and duration for up to 6 months after treatment. Autogenic training might also help adults with migraine. Preliminary clinical research in females with a migraine disorder shows that receiving eight 45-50-minute sessions of biofeedback-assisted autogenic training over 4 weeks reduces the frequency, duration, and intensity of migraines by at least 50% in about 58% of patients, compared to only 20% in the control group.
Insufficient Reliable Evidence To Rate Obsessive-compulsive disorder (OCD)
Preliminary clinical research shows that autogenic training is not an effective method for treating OCD when compared to behavior therapy and fluvoxamine.
Insufficient Reliable Evidence To Rate Pain (chronic)
A meta-analysis of 13 studies in adults with chronic pain shows that autogenic training relieves pain to a moderate extent when compared with passive control groups, but not when compared with other modalities such as progressive muscle relaxation, self-hypnosis, or biofeedback. There was significant heterogeneity in the number and length of autogenic training sessions used in these studies.
Insufficient Reliable Evidence To Rate Parkinson disease
Preliminary clinical research in patients with Parkinson disease grade 2 or 3, shows that autogenic training for 40 sessions over 8 weeks in addition to physical therapy improves motor performance by 52% compared to only 35% in patients practicing physical therapy only.
Insufficient Reliable Evidence To Rate Post-traumatic stress disorder (PTSD)
Preliminary clinical research shows that partaking in autogenic training combined with other mind-body techniques for 6 weeks has beneficial effects in high school students with PTSD. The effect of autogenic training alone on PTSD is unclear.
Insufficient Reliable Evidence To Rate Pre-eclampsia
A small study in primiparous pre-eclamptic patients receiving methyldopa shows that treatment with autogenic training three times weekly for 6 weeks reduces blood pressure and urine protein levels comparably to performing stretching exercises on the same schedule, with average reductions of 13% and 17%, respectively.
Insufficient Reliable Evidence To Rate Psychological well-being
Preliminary clinical research in females with early-stage breast cancer shows that autogenic training may improve anxiety and depressive symptoms when compared to baseline. The validity of this finding is limited by the lack of a control group. A clinical study in healthy people between the ages of 16-20 years shows that 2-hour sessions of autogenic training or mindfulness-oriented meditation training, once weekly at school along with home practice for 8 weeks, produce similar improvements in cooperativeness and emotional symptoms.
Insufficient Reliable Evidence To Rate Raynaud syndrome
Preliminary clinical research shows that autogenic training might improve skin temperature and blood flow in patients with Raynaud syndrome.
Insufficient Reliable Evidence To Rate Rheumatoid arthritis (RA)
Preliminary clinical research in patients with RA receiving standard treatment shows that adding electroacupuncture for 4 weeks seems to improve pain to a greater degree compared to adding autogenic training.
Insufficient Reliable Evidence To Rate Sexual arousal
Preliminary clinical research in healthy, young females shows that a single autogenic training session increases vaginal pulse amplitude, an objective measure of genital sexual arousal, and also subjective ratings of sexual arousal when compared to baseline.
Insufficient Reliable Evidence To Rate Stroke
A clinical study in adults undergoing standard neurological rehabilitation after an ischemic stroke shows that adding autogenic training for 3 weeks improves sense of self-efficacy and level of acceptance similarly to virtual reality sessions incorporating psychotherapy and physical activity. People involved in the virtual reality program had greater improvements in depressive symptoms when compared with autogenic training.
Insufficient Reliable Evidence To Rate Stuttering
Preliminary clinical research shows that autogenic training might improve stuttering in some patients.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
Autogenic training is considered low risk for most healthy adults. It does not involve any substance you swallow, so there is no risk of poisoning, drug toxicity, or contamination.
Still, some people should be cautious. People with serious mental health conditions, such as psychosis or severe depression, should only practice it under the guidance of a trained professional, because deep relaxation techniques can sometimes bring up uncomfortable feelings. People with certain heart conditions, diabetes, or low blood pressure should check with a healthcare provider first, since deep relaxation can affect heart rate and blood pressure.
For pregnancy and breastfeeding, autogenic training is generally viewed as low risk, but research in these groups is limited. To be safe, learn the technique from a qualified instructor and talk with your doctor or midwife before starting. Children should practice with adult or professional guidance.
Side effects
Side effects are uncommon and usually mild. Some people feel slightly dizzy, restless, or anxious during or after a session, especially when first learning. A few people notice unexpected emotions or memories surfacing during deep relaxation.
Rarely, deep relaxation can lower blood pressure or blood sugar in people prone to these problems, which could cause lightheadedness. If you feel unwell during practice, stop and rest. If troubling feelings or symptoms continue, talk with a healthcare provider or a trained instructor.
Dosing
There is no pill or measured "dose" for autogenic training. Instead, it is about regular practice. Many programs suggest practicing for a few minutes, once or several times a day, building up gradually as the technique becomes more natural.
It is often best to learn the steps from a trained therapist, a structured program, or a reputable guided recording or app. Follow the instructions provided with your program. If you have a health condition or take medications, check with your pharmacist or doctor to make sure relaxation practice is appropriate for you.
Autogenic Training & Pregnancy
Autogenic Training & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 25 references that drive our Autogenic Training monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Labbe EE. Treatment of childhood migraine with autogenic training and skin temperature biofeedback: a component analysis. Headache 1995;35:10-13. PubMed
- Groslambert A, Candau R, Grappe F, et al. Effects of autogenic and imagery training on the shooting performance in biathlon. Res Q Exerc Sport 2003;74:337-41. PubMed
- Stetter F, Kupper S. Autogenic training: a meta-analysis of clinical outcome studies. Appl Psychophysiol Biofeedback 2002;27:45-98. PubMed
- Kaluza G, Strempel I. Effects of self-relaxation methods and visual imagery on IOP in patients with open-angle glaucoma. Ophthalmologica 1995;209(3):122-8. PubMed
- Fukunishi I, Hosaka T, Matsumoto T, et al. Liaison psychiatry and HIV infection (II): Application of relaxation in HIV positive patients. Psychiatry Clin Neurosci 1997;51(1):5-8. PubMed
- Simeit R, Deck R, Conta-Marx B. Sleep management training for cancer patients with insomnia. Support Care Cancer 2004;12(3):176-83. PubMed
- Zimmermann-Tansella C, Dolcetta G, et al. Preparation courses for childbirth in primipara. A comparison. J Psychosom Res 1979;23(4):227-33. PubMed
- Nakatani E, Nakagawa A, Nakao T, et al. A randomized controlled trial of Japanese patients with obsessive-compulsive disorder--effectiveness of behavior therapy and fluvoxamine. Psychother Psychosom 2005;74(5):269-76. PubMed
- Noh YE, Morris T, Andersen MB. Psychological intervention programs for reduction of injury in ballet dancers. Res Sports Med 2007;15(1):13-32. PubMed
- Hidderley M, Holt M. A pilot randomized trial assessing the effects of autogenic training in early stage cancer patients in relation to psychological status and immune system responses. Eur J Oncol Nurs 2004;8(1):61-5. PubMed
- Gordon, J. S., Staples, J. K., Blyta, A., and Bytyqi, M. Treatment of posttraumatic stress disorder in postwar Kosovo high school students using mind-body skills groups: a pilot study. J Trauma Stress 2004;17(2):143-147. PubMed
- Ajimsha MS, Majeed NA, Chinnavan E, Thulasyammal RP. Effectiveness of autogenic training in improving motor performances in Parkinson's disease. Complement Ther Med. 2014;22(3):419-25. PubMed
- Asbury EA, Kanji N, Ernst E, Barbir M, Collins P. Autogenic training to manage symptomology in women with chest pain and normal coronary arteries. Menopause. 2009;16(1):60-5. PubMed
- Bernateck M, Becker M, Schwake C, et al. Adjuvant auricular electroacupuncture and autogenic training in rheumatoid arthritis: a randomized controlled trial. Auricular acupuncture and autogenic training in rheumatoid arthritis. Forsch Komplementmed. 2008; PubMed
- Bowden A, Lorenc A, Robinson N. Autogenic Training as a behavioural approach to insomnia: a prospective cohort study. Prim Health Care Res Dev. 2012;13(2):175-85. PubMed
- Kang EH, Park JE, Chung CS, Yu BH. Effect of biofeedback-assisted autogenic training on headache activity and mood states in Korean female migraine patients. J Korean Med Sci. 2009;24(5):936-40. PubMed
- Luciano JV, Martínez N, Peñarrubia-María MT, et al. Effectiveness of a psychoeducational treatment program implemented in general practice for fibromyalgia patients: a randomized controlled trial. Clin J Pain. 2011;27(5):383-91. PubMed
- Stanton A, Meston C. A Single Session of Autogenic Training Increases Acute Subjective and Physiological Sexual Arousal in Sexually Functional Women. J Sex Marital Ther. 2017;43(7):601-617. PubMed
- Awad MA, Hasanin ME, Taha MM, Gabr AA. Effect of stretching exercises versus autogenic training on preeclampsia. J Exerc Rehabil 2019;15(1):109-113. PubMed
- Ramirez-Garcia MP, Leclerc-Loiselle J, Gagnon MP, Côté J, Brouillette MJ, Thomas R. A mixed-method randomized feasibility trial evaluating progressive muscle relaxation or autogenic training on depressive symptoms and quality of life in people living with
- Ramirez Garcia MP, Leclerc-Loiselle J, Côté J, Brouillette MJ, Thomas R. Effect of autogenic training on quality of life and symptoms in people living with HIV: A mixed method randomized controlled trial. Complement Ther Clin Pract 2023;50:101716. PubMed
- Litwic-Kaminska K, Kotysko M, Pracki T, Wilkosc-Debczynska M, Stankiewicz B. The Effect of Autogenic Training in a Form of Audio Recording on Sleep Quality and Physiological Stress Reactions of University Athletes-Pilot Study. Int J Environ Res Public Hea PubMed
- Kiper P, Przysiezna E, Cieslik B, et al. Effects of Immersive Virtual Therapy as a Method Supporting Recovery of Depressive Symptoms in Post-Stroke Rehabilitation: Randomized Controlled Trial. Clin Interv Aging 2022;17:1673-1685. PubMed
- Feruglio S, Pascut S, Matiz A, Paschetto A, Crescentini C. Effects of Mind-Body Interventions on Adolescents' Cooperativeness and Emotional Symptoms. Behav Sci (Basel) 2022;12(2):33. PubMed
- Kohlert A, Wick K, Rosendahl J. Autogenic Training for Reducing Chronic Pain: a Systematic Review and Meta-analysis of Randomized Controlled Trials. Int J Behav Med 2022;29(5):531-542. PubMed
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Autogenic Training: Common Questions
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