Black Rice Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Black Rice interacts with medications. The heart of this page is the interaction list — every drug Black Rice is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Black Rice is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Black Rice against your medication
Add one medicationDrugs that interact with Black Rice
0 medications have a known interaction with Black Rice, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Black Rice. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Black Rice combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Black Rice: Uses, Safety & Side Effects
Black rice is a nutritious whole-grain food that is rich in fiber, plant protein, and antioxidant pigments called anthocyanins. Eaten as part of a balanced diet it is a healthy choice, but strong human evidence that black rice or its extracts treat or prevent specific diseases is still limited. Talk with your pharmacist or doctor before using concentrated black rice supplements.

- Scientific name
- Oryza sativa
- Family
- Poaceae
- Part used
- Whole grain (bran and endosperm)
- Common forms
- Whole grain, cooked rice, flour, rice bran, extracts, and supplement capsules
- Heart health support
- Antioxidant intake
- Digestive and gut health
- Blood sugar and weight management
- General nutrition
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
As a food, black rice is generally safe for most people when eaten in normal amounts.
Insufficient reliable information available; avoid amounts greater than those commonly found in foods.
Read the full pregnancy detailInsufficient reliable information available; avoid amounts greater than those commonly found in foods.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Black rice is a variety of rice (Oryza sativa) that has a deep purple-black color, a nutty flavor, and a slightly chewy texture. It is sometimes called "forbidden rice" because, according to tradition, it was once reserved for royalty in parts of Asia. Today it is widely available in grocery and health-food stores.
Its dark color comes from natural plant pigments called anthocyanins, the same kind of antioxidants found in blueberries and blackberries. Compared with white rice, black rice keeps its bran layer, so it tends to have more fiber, protein, and antioxidants.
People mostly use black rice as a whole-grain food in savory and sweet dishes. It is also sold as flour and, less commonly, as bran or extract supplements marketed for their antioxidant content.
How it works
The most studied compounds in black rice are anthocyanins, the purple-black pigments in its bran. In laboratory research, these act as antioxidants, meaning they may help reduce damage from unstable molecules called free radicals.
Black rice also contains fiber, which supports digestion and helps you feel full, and plant protein and minerals. The fiber may slow the rise in blood sugar after meals compared with refined white rice.
It is important to know that much of this evidence comes from test-tube and animal studies. How well these effects carry over to people eating normal portions of black rice is not fully proven.
Does Black Rice work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
For Black Rice, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.
Also studied for 7 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Age-related cognitive decline
It is unclear if oral black rice extract is beneficial for improving memory in older adults.
Insufficient Reliable Evidence To Rate Allergic rhinitis (hay fever)
Although there is interest in using oral black rice for allergic rhinitis, there is insufficient reliable information about the clinical effects of black rice for this condition.
Insufficient Reliable Evidence To Rate Atopic dermatitis (eczema)
Although there is interest in using oral black rice for eczema, there is insufficient reliable information about the clinical effects of black rice for this condition.
Insufficient Reliable Evidence To Rate Coronary Heart Disease (CHD)
It is unclear if oral black rice pigment is beneficial for improving metabolic parameters in adults with CHD.
Insufficient Reliable Evidence To Rate Hyperlipidemia
It is unclear if oral black rice is beneficial in patients with hyperlipidemia.
Insufficient Reliable Evidence To Rate Obesity
It is unclear if oral black rice extract is beneficial for weight loss in postmenopausal adults.
Insufficient Reliable Evidence To Rate Physical performance
It is unclear if oral black rice improves physical performance in older adults.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
As a food, black rice is generally safe for most people and can be prepared and eaten like other rice. It is naturally gluten-free, which can make it useful for people avoiding gluten.
Like all rice, black rice can absorb arsenic from soil and water. To lower exposure, you can rinse rice well before cooking, cook it in extra water, and eat a variety of grains rather than rice at every meal.
People with diabetes or who count carbohydrates should remember that black rice is still a starchy food and should be counted in meal planning. If you are considering concentrated black rice extracts or supplements, talk with your pharmacist or doctor first, since these are not well studied.
Pregnancy and breastfeeding: Black rice is fine to eat as a normal food during pregnancy and breastfeeding. However, concentrated supplements and extracts have not been tested for safety in these groups, so it is best to avoid them unless your healthcare provider approves.
Side effects
Black rice eaten as a food rarely causes problems. Because it is high in fiber, eating large amounts—especially if you are not used to it—may cause gas, bloating, or changes in bowel habits.
Allergic reactions to rice are uncommon but possible. Stop using it and seek care if you notice rash, itching, swelling, or trouble breathing.
Little is known about the side effects of concentrated black rice extracts, so use such products cautiously and only as directed.
Dosing
There is no established medicinal dose for black rice. As a food, a typical serving is a cooked portion similar to other rice, included as part of a balanced diet.
For supplements or extracts, follow the directions on the product label, since amounts vary by product and have not been standardized. Because these products are not well studied, check with your pharmacist or doctor before starting one, especially if you have a health condition or take other medicines.
Black Rice & Pregnancy
Black Rice & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 2 sources that drive our Black Rice monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.
- Arsenic in Rice and Rice Products — U.S. Food and Drug Administration (FDA) Source
- Dietary Fiber — MedlinePlus (NIH) Source
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Brands that make products with Black Rice
13 brands in our database make a supplement containing Black Rice.
Supplement products with Black Rice
37 products in our database contain Black Rice. Open any to see its full ingredient list and every drug interaction we check.
Black Rice: Common Questions
What is Black Rice used for, and does it work?
Does Black Rice interact with prescription medications?
How are Black Rice interactions rated?
Is it safe to take Black Rice with my medications?
Where does this Black Rice interaction information come from?
What is Black Rice used for?
Is Black Rice healthier than white rice?
Is Black Rice safe during pregnancy?
Can Black Rice cause any side effects?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Black Rice
A rotating sample of real supplements in our database that list Black Rice — open any to see its full ingredients and every drug interaction we check.
- Plant-Based Protein 20 g Vanilla by California Gold Nutrition SPORT
- Oxidation Mender by BioAnue
- Black Rice Extract by BioAnue
- AntiOxidant Synergy by SuperSmart
- Global Greens by MRM
- Formula 503X 460 mg by TumoRx
- Formula 503X 460 mg by TumoRx
- Black Rice Extract by BulkSupplements.com
- Black Rice Extract by BioAnue
- Black Rice Extract by BulkSupplements.com
Have a question about Black Rice?
Our pharmacists answer your medication & supplement questions — free.