Herb & supplement monograph

Buck's-horn Plantain Drug Interactions, Uses, Safety & More

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Interaction report

Drugs that interact with Buck's-horn Plantain

0 medications have a known interaction with Buck's-horn Plantain, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Buck's-horn Plantain. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Buck's-horn Plantain combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Buck's-horn Plantain: Uses, Safety & Side Effects

The bottom line

Buck's-horn plantain (Plantago coronopus) is mainly a edible coastal salad green that has also been used in folk medicine for digestion and minor skin or urinary complaints. There is very little human research to support any medicinal use, so it should be viewed as a nutritious food rather than a proven remedy. If you want to use it for a health condition, talk with a pharmacist or doctor first.

Scientific name
Plantago coronopus
Family
Plantaginaceae
Part used
Leaves (and sometimes seeds)
Common forms
Fresh leaves (as a salad green or potherb), dried herb, tea/infusion, occasionally poultices
People commonly use it for
  • Eaten as a leafy salad green
  • Digestive complaints
  • Soothing irritated skin (topical, traditional)
  • Mild diuretic (traditional)
  • General tonic in folk medicine

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Generally considered safe as a food, but medicinal use is poorly studied.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Buck's-horn plantain is a low-growing plant with narrow, deeply toothed leaves whose shape is said to resemble a deer's antlers, which is how it got its name. Its scientific name is Plantago coronopus, and it belongs to the plantain family (Plantaginaceae). It is not related to the banana-like tropical plantain.

It grows wild along coasts and in sandy, salty soils across Europe, the Mediterranean, North Africa, and parts of Asia, and it has spread to other regions. The plant tolerates salt well, so it is sometimes grown as a specialty salad green sometimes sold under names like "minutina" or "erba stella."

People most often eat the young leaves raw in salads or cook them like spinach. In traditional folk medicine the leaves have also been used for digestive and minor skin or urinary complaints.

Uses & effectiveness

Most of what we know about buck's-horn plantain comes from its long use as a food and from traditional medicine, not from high-quality human studies. There is limited to no reliable clinical evidence showing it treats any specific medical condition.

Traditionally, the leaves have been used to ease digestive upset, as a mild diuretic, and applied to skin to soothe irritation or minor wounds. Like other plantain species, it contains plant compounds and fiber that may have mild soothing effects, but this has not been well proven for Plantago coronopus specifically.

As a vegetable, it is a source of vitamins, minerals, and antioxidants, and some laboratory studies report antioxidant activity in its extracts. These lab findings are interesting but do not prove any health benefit in people.

How it works

The plant contains compounds common to the plantain family, including mucilage (a soothing, gel-like fiber), flavonoids, phenolic acids, and iridoid glycosides. In test-tube studies, these compounds can show antioxidant and mild anti-inflammatory activity.

The mucilage may help explain its traditional use for digestion and for soothing skin, since this type of fiber can form a protective, slippery coating. Most of these mechanisms are based on laboratory or animal research, and it is not clear how strongly, if at all, they apply when the plant is eaten or used by people.

Safety & precautions

Eaten as a normal food or salad green, buck's-horn plantain is generally regarded as safe for most healthy people. Safety information about medicinal or concentrated forms, such as strong teas or extracts, is very limited.

People with allergies to plantain plants or to pollen should be cautious, as allergic reactions are possible. Anyone with a medical condition or who takes regular medication should check with a pharmacist or doctor before using it as a remedy.

Because there is not enough safety data, women who are pregnant or breastfeeding should avoid medicinal amounts and stick to using it only as an occasional food, if at all. The same caution applies to giving it to young children for medicinal purposes.

Side effects

When eaten as a vegetable, buck's-horn plantain is not known to cause significant problems. As with any high-fiber plant, large amounts could cause mild bloating, gas, or loose stools in some people.

Allergic reactions are possible but uncommon. Stop using it and seek medical care if you notice itching, rash, swelling, or trouble breathing. Because the plant often grows near coasts and roadsides, only eat plants you are sure are clean and correctly identified.

Dosing

There is no established standardized medicinal dose for buck's-horn plantain. It is most often used simply as a food, in the amounts you would eat any leafy green.

If you choose to use a commercial product such as a dried herb or tea, follow the directions on the label and do not exceed the recommended amount. Because reliable dosing information is lacking, it is best to check with a pharmacist or doctor before using it for any health purpose.

Pregnancy & Breastfeeding

Buck's-horn Plantain & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Buck's-horn Plantain & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 sources that drive our Buck's-horn Plantain monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.

  1. Plantain (Plantago) information — MedlinePlus Source
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Pharmacist Counseling Corner

Buck's-horn Plantain: Common Questions

Does Buck's-horn Plantain interact with prescription medications?
We do not currently list any known drug interactions for Buck's-horn Plantain. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Buck's-horn Plantain interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Buck's-horn Plantain with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Buck's-horn Plantain interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Buck's-horn Plantain used for?
It is mainly eaten as a salad green or cooked vegetable. In folk medicine it has also been used for digestive complaints and to soothe skin, but there is little scientific evidence that it works as a remedy.
Is Buck's-horn Plantain safe to eat?
Yes, it is generally considered safe as a food for most healthy people. Just make sure the plant is correctly identified and clean before eating it.
Can I take it while pregnant or breastfeeding?
There isn't enough safety information for medicinal use, so it's best to avoid concentrated forms during pregnancy and breastfeeding and to check with your doctor first.
Is Buck's-horn Plantain the same as the plantain you eat like a banana?
No. Buck's-horn Plantain is a small leafy herb in the Plantago family and is completely unrelated to the starchy, banana-like cooking plantain.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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