Herb & supplement monograph

Hexadrone Drug Interactions, Uses, Safety & More

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Interaction report

Drugs that interact with Hexadrone

0 medications have a known interaction with Hexadrone, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Hexadrone. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Hexadrone combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Hexadrone: Uses, Safety & Side Effects

The bottom line

Hexadrone is a synthetic oral anabolic steroid (a 'prosteroid' or designer steroid) marketed in bodybuilding supplements, not a natural herb or vitamin. It is not an approved drug, its safety has not been established in proper human studies, and like other anabolic steroids it can stress the liver, cholesterol, and hormones. We do not recommend using it, and you should talk to a doctor or pharmacist before considering any product containing it.

Part used
Synthetic compound (not a plant part)
Common forms
Capsules, tablets
People commonly use it for
  • Muscle building (bodybuilding)
  • Strength gains
  • Body recomposition
  • Athletic performance

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallBest avoided

An unapproved synthetic anabolic steroid with serious potential health risks and little safety data.

PregnancyPossibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including red...

Read the full pregnancy detail
BreastfeedingPossibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including red...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Hexadrone is not an herb or a vitamin. It is a synthetic compound sold in the bodybuilding and 'sports supplement' market as a so-called prohormone or designer anabolic steroid. Products like this are designed to act in the body in a way similar to anabolic-androgenic steroids (the same family as testosterone-based drugs).

Even though it has been sold in capsules and tablets labeled as a 'dietary supplement,' Hexadrone does not come from a food, plant, or traditional remedy. It is a man-made steroid-type chemical. Many compounds of this kind have been pulled from the market or flagged by health authorities because of safety concerns.

People who use Hexadrone are usually trying to gain muscle, increase strength, or change their body composition. It is important to understand that legitimate, high-quality safety research on this specific compound is essentially absent.

Uses & effectiveness

Hexadrone is popularly used by some bodybuilders and gym-goers who hope to build muscle, gain strength, or lose fat while keeping muscle. These are marketing claims and traditions within the bodybuilding community, not proven medical uses.

The evidence is very weak. There are no large, well-designed human clinical trials showing that Hexadrone safely and effectively does what it is marketed to do. Much of what is said about it comes from manufacturer claims, online forums, and personal anecdotes rather than reliable science.

Because it behaves like an anabolic steroid, it is biologically possible it could affect muscle. But that does not make it safe or appropriate, and any potential benefit must be weighed against real risks to the liver, heart, and hormones.

How it works

Hexadrone is thought to act as an anabolic-androgenic steroid or a compound that the body converts into one. In simple terms, these chemicals attach to androgen receptors in the body — the same receptors that respond to testosterone — which can signal muscle cells to grow.

This proposed mechanism is based on how the broader class of anabolic steroids behaves, not on detailed studies of Hexadrone itself. The exact way this specific compound is processed in the human body, how much reaches the bloodstream when swallowed, and what byproducts it forms are not well documented in reliable research.

Safety & precautions

We urge real caution here. Oral anabolic steroid-type compounds are linked to a range of serious health problems, including liver damage, worsening cholesterol (lower 'good' HDL and higher 'bad' LDL), high blood pressure, and disruption of the body's own hormone production. Because Hexadrone is unregulated, the actual contents and purity of any given product are uncertain.

People with liver problems, heart disease, high cholesterol, hormone-sensitive conditions, or any chronic illness should not use it. Teenagers and young adults whose bodies are still developing should especially avoid these compounds.

Pregnancy: Avoid completely. Anabolic steroids can cause serious harm to a developing baby, including abnormal sexual development. Breastfeeding: Also avoid, because these compounds can pass to the baby and their effects are unsafe. If you are pregnant, breastfeeding, or trying to conceive, do not use Hexadrone.

Athletes should also know that steroid-type compounds like this are typically banned by sports organizations and can cause a failed drug test.

Side effects

Reported and expected side effects of anabolic steroid-type compounds include:

  • Liver stress or injury (sometimes shown by yellowing skin, dark urine, or fatigue)
  • Worsening cholesterol and increased cardiovascular risk
  • Acne and oily skin
  • Hair loss or unwanted hair growth
  • Mood changes, irritability, or aggression
  • Suppression of natural testosterone, which can cause low libido, low energy, and shrinking of the testicles in men
  • In women: deepening voice, facial hair, and menstrual changes (some of which may be permanent)

Rare but serious harms can include severe liver injury and cardiovascular events. If you take a product like this and feel unwell — especially yellow skin, severe abdominal pain, or chest symptoms — stop and seek medical care right away.

Dosing

There is no established, medically recommended dose for Hexadrone, because it is not an approved medicine and has not been properly studied in humans. The doses suggested on product labels or in online forums are not backed by safety testing.

Because of the real health risks, our pharmacist guidance is to not use this compound. If you are considering it or already taking it, please speak with a doctor or pharmacist, and consider getting blood work (such as liver function and cholesterol) to check on your health.

Pregnancy & Breastfeeding

Hexadrone & Pregnancy

Possibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous. Avoid using.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100.

Hexadrone & Breastfeeding

Possibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous. Avoid using.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 references that drive our Hexadrone monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Product directory

Supplement products with Hexadrone

19 products in our database contain Hexadrone. Open any to see its full ingredient list and every drug interaction we check.

Decimation Pro-Tren Stack by DNA Anabolics Capsule 90 Capsule(s) View ingredients & interactions Neanderthal Pro-Tren Stack by DNA Anabolics Capsule 90 Capsule(s) View ingredients & interactions 6 Alpha by Olympus Performance Capsule 60 Capsule(s) Off market View ingredients & interactions AlphaLean by Olympus Performance Capsule 60 Capsule(s) Off market View ingredients & interactions AlphaPlex by Olympus Performance Capsule 60 Capsule(s) Off market View ingredients & interactions AlphaShred by Olympus Performance Capsule 60 Capsule(s) Off market View ingredients & interactions AlphaTren by Olympus Performance Capsule 60 Capsule(s) Off market View ingredients & interactions Dragon's Blood by Xcel Sports Nutrition Liquid 40 Serving(s) Off market View ingredients & interactions Kill Shot by Xcel Sports Nutrition Capsule 90 Capsule(s) Off market View ingredients & interactions Mammoth DNA by Xcel Sports Nutrition Capsule 60 Capsule(s) Off market View ingredients & interactions Mammoth DNA by Xcel Sports Nutrition Capsule 60 Capsule(s) Off market View ingredients & interactions Mammoth DNA Resurrection by Xcel Sports Nutrition Capsule 60 Capsule(s) Off market View ingredients & interactions Mammoth Resurrection by Axxcelerated Sports Nutrition Capsule 60 Capsule(s) Off market View ingredients & interactions Mass Plexx by Alpha Labs Capsule 60 Capsule(s) Off market View ingredients & interactions Reaper DNA Resurrection by Xcel Sports Nutrition Capsule 60 Capsule(s) Off market View ingredients & interactions Reaper Resurrection by Axxcelerated Sports Nutrition Capsule 60 Capsule(s) Off market View ingredients & interactions Super Epi Tren6 by Warrior Labz Capsule 60 Capsule(s) Off market View ingredients & interactions Tren Devastation by Xcel Sports Nutrition Liquid 40 Serving(s) Off market View ingredients & interactions Yetti Resurrection by Axxcelerated Sports Nutrition Capsule 60 Capsule(s) Off market View ingredients & interactions
Pharmacist Counseling Corner

Hexadrone: Common Questions

Does Hexadrone interact with prescription medications?
We do not currently list any known drug interactions for Hexadrone. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Hexadrone interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Hexadrone with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Hexadrone interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
Is Hexadrone a natural herb or supplement?
No. Despite being sold as a 'dietary supplement,' Hexadrone is a man-made anabolic steroid-type compound, not a plant or natural remedy.
Is Hexadrone safe to take?
We do not consider it safe. It can stress the liver, harm cholesterol and heart health, and disrupt your natural hormones, and it has not been properly tested in humans.
Can I use Hexadrone while pregnant or breastfeeding?
No. Anabolic steroid compounds can seriously harm a developing baby or nursing infant, so it must be avoided during pregnancy and breastfeeding.
Will Hexadrone make me fail a drug test?
Very likely yes. Steroid-type compounds like this are banned by most sports organizations and can cause a positive doping test.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Products that contain Hexadrone

A rotating sample of real supplements in our database that list Hexadrone — open any to see its full ingredients and every drug interaction we check.

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