Herb & supplement monograph

Monterey Pine Drug Interactions, Uses, Effectiveness, Safety & More

Check Monterey Pine against your medication

Add one medication
Monterey Pine
+
Start typing any prescription or over-the-counter drug name.
Reviewed by licensed pharmacists Sourced from Natural Medicines
Interaction report

Drugs that interact with Monterey Pine

0 medications have a known interaction with Monterey Pine, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Monterey Pine. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Monterey Pine combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Monterey Pine: Uses, Safety & Side Effects

The bottom line

Monterey Pine is mainly a timber tree, and human evidence for its use as a supplement is very limited. Some pine bark extracts are studied for antioxidant effects, but most claims specific to Monterey Pine are not well proven. Talk to a pharmacist or doctor before using any pine-based product.

Monterey Pine
Scientific name
Pinus radiata
Family
Pinaceae
Part used
Bark, needles, and essential oil
Common forms
Bark extract supplements, essential oil, needle tea
People commonly use it for
  • Antioxidant support
  • Skin and aging concerns
  • Circulation support
  • Inflammation
  • Respiratory comfort

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallLimited data

There is little human safety data for Monterey Pine taken as a supplement.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Monterey Pine (Pinus radiata) is a fast-growing evergreen tree that is native to a small part of California's central coast. Because it grows quickly and produces useful wood, it has been planted widely around the world, especially in places like New Zealand, Australia, Chile, and Spain, mostly for timber and paper.

While the tree is best known for forestry, parts of it such as the bark, needles, and essential oil are sometimes used in supplements, skincare, and aromatherapy. Pine bark extracts in general have drawn interest for their natural plant compounds. It is important to know that most research on "pine bark" focuses on other pine species, not specifically on Monterey Pine.

How it works

Pine bark and needles contain plant compounds such as proanthocyanidins (a type of flavonoid), other polyphenols, and aromatic oils made of terpenes. In laboratory and animal studies, these compounds can act as antioxidants, meaning they may help neutralize unstable molecules called free radicals.

Researchers have also looked at whether pine polyphenols affect blood vessels and inflammation. These ideas are mostly based on test-tube and animal research, so it is not clear how well they apply to people taking Monterey Pine products. The essential oil's scent and terpenes are why pine oils are popular in aromatherapy.

Effectiveness

Does Monterey Pine work?

Evidence overview · 5 uses evaluated
5 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Monterey Pine, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 5 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Cardiovascular disease (CVD)
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral Monterey pine for preventing CVD, there is insufficient reliable information about the clinical effects of Monterey pine for this condition.

Insufficient Reliable Evidence To Rate Cognitive function
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral Monterey pine bark extract improves cognition.

Insufficient Reliable Evidence To Rate Migraine headache
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral Monterey pine for preventing migraine headache, there is insufficient reliable information about the clinical effects of Monterey pine for this condition.

Insufficient Reliable Evidence To Rate Neurological trauma
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral Monterey pine bark extract is beneficial in patients with neurological trauma.

Insufficient Reliable Evidence To Rate Traumatic brain injury (TBI)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral Monterey pine bark extract is beneficial in patients with TBI.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

There is not much human safety information about taking Monterey Pine as a supplement. As a general rule, treat it cautiously. People with allergies to pine, conifer pollen, or related plants should be especially careful, since reactions are possible.

The essential oil should never be swallowed unless directed by a qualified professional, as concentrated pine oils can be toxic if taken by mouth. Keep oils away from children and pets. Because safety is not established, women who are pregnant or breastfeeding should avoid Monterey Pine products. Anyone with a chronic health condition or who takes regular medicines should check with a pharmacist or doctor first.

Side effects

Reported side effects for pine-based supplements are usually mild and may include stomach upset, nausea, or headache. Applying pine oil to the skin can cause irritation or allergic skin reactions in some people, so a patch test is wise before wider use.

More serious problems are mainly linked to swallowing essential oil, which can cause poisoning, breathing trouble, or other dangerous effects. Stop use and seek medical care if you have signs of an allergic reaction such as rash, swelling, or difficulty breathing.

Monterey Pine: Reported Adverse Effects

Documented safety reports on Monterey Pine from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Reports by condition
Dermatitis Dermatologic
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no established standard dose for Monterey Pine. Because products vary widely in strength and form, a safe, proven amount has not been set.

If you choose to use a pine-derived product, follow the directions on the label and do not exceed them. Essential oils are for external or aromatherapy use only unless a professional advises otherwise. When in doubt, ask a pharmacist to help you review the product and decide if it is appropriate for you.

Pregnancy & Breastfeeding

Monterey Pine & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Monterey Pine & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 references that drive our Monterey Pine monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Burry, J. N. Environmental dermatitis: contact dermatitis from Pinus radiata. Med J Aust. 7-2-1977;2(1):13-14. DOI
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Product directory

Supplement products with Monterey Pine

43 products in our database contain Monterey Pine. Open any to see its full ingredient list and every drug interaction we check.

Relax & Focus by ENZO Capsule 60 Capsule(s) View ingredients & interactions SkinElixir Acai Flavor by Arbonne Powder 30 Stick Pack(s) · 3.81 Ounce(s) · 108 Gram(s) View ingredients & interactions SkinElixir Acai Flavor by Arbonne Powder 30 Stick Pack(s) · 3.81 Ounce(s) · 108 Gram(s) View ingredients & interactions SkinElixir Collagen Builder Acai Flavor by Arbonne Powder 30 Stick Pack(s) · 3.81 Ounce(s) · 108 Gram(s) View ingredients & interactions SkinElixir Dragon Fruit Flavor by Arbonne Powder 30 Stick Pack(s) · 3.81 Ounce(s) · 108 Gram(s) View ingredients & interactions Animal Pak by Animal Other (e.g. Tea Bag) 44 Pack(s) Off market View ingredients & interactions Corvalen Ribose OPC by Douglas Laboratories Powder 5.8 Oz(s) · 165 Gram(s) Off market View ingredients & interactions CurcumaSorb Mind by Pure Encapsulations Capsule 60 Capsule(s) Off market View ingredients & interactions Fibrinogen Resist With Nattokinase by Life Extension Capsule 30 Vegetarian Capsule(s) Off market View ingredients & interactions Healthy Skin Within Skin Elixir by Arbonne Powder 30 Stick Pack(s) Off market View ingredients & interactions Joint, Tendon, Ligament I by Douglas Laboratories Capsule 90 Vegetarian Capsule(s) Off market View ingredients & interactions Million ORAC Standardized Extracts by ProCaps Laboratories Capsule 360 Easy To Swallow Capsule(s) Off market View ingredients & interactions MM6 For Men by Nugevity Tablet Or Pill 30 Daily Packet(s) Off market View ingredients & interactions MM6 For Men by Nugevity Other (e.g. Tea Bag) 30 Daily Packet(s) Off market View ingredients & interactions PM Pack by Douglas Laboratories Other (e.g. Tea Bag) 60 Pack(s) · 30 PM Pack(s) · 30 AM Pack(s) Off market View ingredients & interactions Professional by ENZO Nutraceuticals Capsule 60 Capsule(s) Off market View ingredients & interactions Relax & Focus by ENZO Capsule 60 Capsule(s) Off market View ingredients & interactions SkinElixir Acai Flavor by Arbonne Powder 30 Stick Pack(s) · 3.81 Ounce(s) · 108 Gram(s) Off market View ingredients & interactions Ultra Benfotiamine by Douglas Laboratories Capsule 60 Vegetarian Capsule(s) Off market View ingredients & interactions
Pharmacist Counseling Corner

Monterey Pine: Common Questions

What is Monterey Pine used for, and does it work?
People use Monterey Pine for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Monterey Pine interact with prescription medications?
We do not currently list any known drug interactions for Monterey Pine. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Monterey Pine interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Monterey Pine with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Monterey Pine interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Monterey Pine used for?
It is mainly a timber tree, but its bark, needles, and oil are sometimes used for antioxidant support, skin care, circulation, and aromatherapy. Most of these uses are traditional and not well proven for this specific species.
Is Monterey Pine safe to take?
There is little human data on taking it as a supplement, so safety is unknown. Be cautious, never swallow the essential oil unless a professional directs it, and check with a pharmacist first.
Can I use Monterey Pine while pregnant or breastfeeding?
No reliable safety information exists, so it is best to avoid it during pregnancy and breastfeeding.
Is Monterey Pine the same as the pine bark extract sold in stores?
Not necessarily. Most studied pine bark extracts come from other pine species, so research on those products may not apply to Monterey Pine.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Have a question about Monterey Pine?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist