Mouse-ear Hawkweed Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Mouse-ear Hawkweed interacts with medications. The heart of this page is the interaction list — every drug Mouse-ear Hawkweed is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Mouse-ear Hawkweed is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Mouse-ear Hawkweed against your medication
Add one medicationDrugs that interact with Mouse-ear Hawkweed
0 medications have a known interaction with Mouse-ear Hawkweed, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Mouse-ear Hawkweed. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Mouse-ear Hawkweed combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Mouse-ear Hawkweed: Uses, Safety & Side Effects
Mouse-ear hawkweed is a traditional European herb used mainly for urinary, digestive, and respiratory complaints, but modern human studies are very limited. Because good safety and effectiveness data are lacking, it is best used cautiously and avoided in pregnancy and breastfeeding. Talk with your pharmacist or doctor before trying it, especially if you have a health condition or take medications.

- Scientific name
- Pilosella officinarum
- Family
- Asteraceae
- Part used
- Aerial parts (leaves, flowers, and stems), usually the whole flowering herb
- Common forms
- Tea (infusion), liquid extract or tincture, dried herb, capsules
- Urinary tract and kidney support
- Mild diuretic (increasing urine flow)
- Digestive complaints
- Coughs and respiratory irritation
- Wound and skin care (astringent)
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Traditionally used but lacking modern human safety and effectiveness data, so use cautiously.
Insufficient reliable information available; avoid using.
Read the full pregnancy detailInsufficient reliable information available; avoid using.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Mouse-ear hawkweed (Pilosella officinarum, also known as Hieracium pilosella) is a small perennial plant in the daisy family (Asteraceae). It grows low to the ground in a rosette of soft, hairy leaves and produces slender stems topped with small yellow, dandelion-like flowers.
The plant is native to Europe and parts of Asia and is also found in North America, often growing in dry fields, grassy areas, and along roadsides. The aerial parts (leaves, stems, and flowers) have a long history of use in traditional European herbal medicine.
People have traditionally taken it as a tea, tincture, or extract for urinary, digestive, and respiratory complaints. It is sometimes applied to the skin as an astringent. Today it is found mostly in herbal product blends rather than as a mainstream supplement.
How it works
Mouse-ear hawkweed contains several plant compounds that may explain its traditional uses. These include flavonoids and other polyphenols (antioxidants), coumarins such as umbelliferone, and tannins, which have an astringent (tightening) effect on tissues.
The tannins may account for its traditional use on minor wounds and for digestive complaints, while certain compounds are thought to have mild diuretic and antimicrobial properties. Laboratory studies have reported antioxidant and antibacterial activity for plant extracts.
It is important to know that this information is based mostly on test-tube and animal research. How these compounds behave in the human body, and at what doses they might matter, is not well understood.
Does Mouse-ear Hawkweed work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
For Mouse-ear Hawkweed, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.
Also studied for 2 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Flatulence
Although there has been interest in using oral mouse-ear hawkweed for flatulence, there is insufficient reliable information about the clinical effects of mouse-ear hawkweed for this purpose.
Insufficient Reliable Evidence To Rate Wound healing
Although there has been interest in using topical mouse-ear hawkweed for wound healing, there is insufficient reliable information about the clinical effects of mouse-ear hawkweed for this purpose.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
There is not much modern safety data on mouse-ear hawkweed. Because it belongs to the daisy (Asteraceae) family, people who are allergic to ragweed, marigolds, daisies, chrysanthemums, or related plants may be more likely to have an allergic reaction.
People with kidney disease or who are prone to dehydration should be cautious because of its possible diuretic (water-losing) effect. If you have an ongoing health condition or take prescription medicines, check with a pharmacist or doctor first.
Pregnancy and breastfeeding: There is no reliable safety information for these situations. To be safe, mouse-ear hawkweed should be avoided during pregnancy and while breastfeeding.
Do not use it as a substitute for proper medical care, especially for a suspected infection or kidney stones.
Side effects
Reported side effects are not well documented because the herb has not been studied closely in people. Based on its makeup and how similar herbs behave, possible effects include stomach upset and increased urination from its diuretic action.
The biggest concern is allergic reaction, particularly in people sensitive to plants in the daisy family. Stop using it and seek medical care if you develop a rash, itching, swelling, or trouble breathing.
Because real-world safety information is limited, start with caution and watch for any unusual reactions.
Dosing
There is no established standard dose for mouse-ear hawkweed. Traditional use has involved teas made from the dried herb and liquid extracts or tinctures, but reliable, science-based dosing is not available.
If you choose to use a product, follow the directions on the label and do not exceed the suggested amount. Because product strength and quality can vary widely between brands, choose products from reputable manufacturers.
The safest approach is to talk with a pharmacist or doctor before starting, so they can review your health history and current medications.
Mouse-ear Hawkweed & Pregnancy
Mouse-ear Hawkweed & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 3 sources that drive our Mouse-ear Hawkweed monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing.
- Hawkweed (Hieracium) information — MedlinePlus Source
- Using Dietary Supplements Wisely — NIH NCCIH Source
- Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Mouse-ear Hawkweed: Common Questions
What is Mouse-ear Hawkweed used for, and does it work?
Does Mouse-ear Hawkweed interact with prescription medications?
How are Mouse-ear Hawkweed interactions rated?
Is it safe to take Mouse-ear Hawkweed with my medications?
Where does this Mouse-ear Hawkweed interaction information come from?
What is Mouse-ear Hawkweed used for?
Is Mouse-ear Hawkweed safe?
Can I take it during pregnancy or breastfeeding?
How is Mouse-ear Hawkweed usually taken?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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