Rose Geranium Oil Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Rose Geranium Oil interacts with medications. The heart of this page is the interaction list — every drug Rose Geranium Oil is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Rose Geranium Oil is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Rose Geranium Oil against your medication
Add one medicationDrugs that interact with Rose Geranium Oil
0 medications have a known interaction with Rose Geranium Oil, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Rose Geranium Oil. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Rose Geranium Oil combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Rose Geranium Oil: Uses, Safety & Side Effects
Rose geranium oil is an essential oil distilled from the leaves of Pelargonium graveolens, used mainly in aromatherapy, skincare, and as a natural fragrance. High-quality human evidence for medical benefits is limited, and like all essential oils it must be diluted before skin use and never swallowed. Talk to a pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have sensitive skin.
- Scientific name
- Pelargonium graveolens
- Family
- Geraniaceae
- Part used
- Leaves and stems (steam-distilled essential oil)
- Common forms
- Essential oil, diluted topical blends, aromatherapy products, soaps and skincare items
- Skin care and complexion
- Aromatherapy for stress and mood
- Insect and tick repellent
- Minor wound and skin soothing
- Fragrance
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Generally considered safe for diluted topical or aromatherapy use, but it can irritate skin and should not be swallowed.
Insufficient reliable information available; avoid amounts greater than those found in foods.
Read the full pregnancy detailInsufficient reliable information available; avoid amounts greater than those found in foods.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Rose geranium oil is an essential oil made by steam-distilling the leaves and stems of Pelargonium graveolens, a flowering plant in the geranium family. It is called "rose" geranium because the oil has a sweet, rose-like scent. The plant is native to southern Africa and is now grown in many warm regions, including parts of Europe, North Africa, and the islands of Réunion and Madagascar.
People most often use rose geranium oil in aromatherapy, perfumes, soaps, lotions, and other skincare products. In folk and traditional practices it has also been applied to the skin (always diluted) for minor irritation or used as a natural insect repellent. It is a fragrance and topical product, not something meant to be eaten.
How it works
Rose geranium oil contains a mix of aromatic compounds, with citronellol and geraniol usually among the main ones, along with smaller amounts of others like linalool. These are the compounds that give the oil its rose-like smell.
In laboratory studies, these compounds have shown antioxidant, anti-inflammatory, and germ-slowing activity, and the scent may affect mood through the sense of smell. However, most of this research is from test tubes or animals. It is not clear how well these effects carry over to real-world use in people, so the proposed mechanisms should be viewed as preliminary.
Does Rose Geranium Oil work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
For Rose Geranium Oil, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.
Also studied for 4 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Hereditary hemorrhagic telangiectasia (HHT)
It is unclear if topical rose geranium oil is beneficial for epistaxis in patients with HHT.
Insufficient Reliable Evidence To Rate Neuropathic pain
Although there has been interest in using oral and topical rose geranium oil for neuropathic pain, there is insufficient reliable information about the clinical effects of rose geranium oil for this purpose.
Insufficient Reliable Evidence To Rate Postherpetic neuralgia
It is unclear if topical rose geranium oil is beneficial in patients with postherpetic neuralgia.
Insufficient Reliable Evidence To Rate Wound healing
Although there has been interest in using topical rose geranium oil for wound healing, there is insufficient reliable information about the clinical effects of rose geranium oil for this purpose.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
For most healthy adults, rose geranium oil is considered reasonably safe when properly diluted and used on the skin or smelled in aromatherapy. Like all essential oils, it is highly concentrated and should never be swallowed unless directed by a qualified professional.
Always dilute it in a carrier oil (such as jojoba or coconut oil) before applying to skin, and do a small patch test first. People with sensitive skin, eczema, allergies, or a history of reacting to fragrances should be especially cautious. Keep it away from the eyes and out of reach of children and pets.
Pregnancy and breastfeeding: Because its safety has not been well studied in these situations, it is best to avoid medicinal use during pregnancy and while breastfeeding. Casual exposure to the scent in a finished cosmetic product is less of a concern, but check with your doctor or pharmacist if you have questions.
Side effects
The most common problems are skin-related, such as redness, itching, rash, or irritation, especially if the oil is used undiluted or on sensitive skin. Some people can develop an allergic skin reaction (contact dermatitis) to fragrance components.
If swallowed, essential oils can cause more serious effects, including stomach upset and, in larger amounts, more dangerous reactions. If a child swallows essential oil, seek medical help or contact poison control right away. Stop using the oil and see a healthcare provider if you develop a significant rash, swelling, or trouble breathing.
Rose Geranium Oil: Reported Adverse Effects
Documented safety reports on Rose Geranium Oil from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
Reports by conditionDermatitis Dermatologic
Topically, rose geranium oil has been associated with reports of dermatitis in hypersensitive individuals and burning sensations when applied to the face.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no established standardized medical dose for rose geranium oil. It is used mainly topically (in diluted form) or by inhaling its scent, not by mouth.
For skin use, essential oils are typically mixed at a low concentration in a carrier oil, but you should follow the specific instructions on your product label. Because products vary in strength and quality, it is wise to start with the smallest amount, patch test first, and check with a pharmacist or doctor before regular use.
Rose Geranium Oil & Pregnancy
Rose Geranium Oil & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 1 references that drive our Rose Geranium Oil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Greenway FL, Frome BM, Engels TM. Temporary relief of postherpetic neuralgia pain with topical geranium oil. Am J Med 2003;115:586-7. PubMed
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Rose Geranium Oil
3 brands in our database make a supplement containing Rose Geranium Oil.
Supplement products with Rose Geranium Oil
5 products in our database contain Rose Geranium Oil. Open any to see its full ingredient list and every drug interaction we check.
Rose Geranium Oil: Common Questions
What is Rose Geranium Oil used for, and does it work?
Does Rose Geranium Oil interact with prescription medications?
How are Rose Geranium Oil interactions rated?
Is it safe to take Rose Geranium Oil with my medications?
Where does this Rose Geranium Oil interaction information come from?
What is Rose Geranium Oil used for?
Can I put Rose Geranium Oil directly on my skin?
Is Rose Geranium Oil safe to swallow?
Is it safe during pregnancy or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Rose Geranium Oil
A rotating sample of real supplements in our database that list Rose Geranium Oil — open any to see its full ingredients and every drug interaction we check.
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