Storax Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Storax interacts with medications. The heart of this page is the interaction list — every drug Storax is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Storax is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Storax against your medication
Add one medicationDrugs that interact with Storax
0 medications have a known interaction with Storax, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Storax. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Storax combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Storax: Uses, Safety & Side Effects
Storax is an aromatic balsam (resin) tapped from Liquidambar trees, used traditionally as a topical antiseptic, a remedy for skin parasites, and a respiratory aid. Modern human evidence for its health benefits is very limited, and it can cause skin irritation or allergic reactions, so use it cautiously and check with a pharmacist or doctor first.
- Scientific name
- Liquidambar orientalis
- Family
- Altingiaceae
- Part used
- Balsam (resin) from the trunk bark
- Common forms
- Balsam (resin), tincture, topical ointments and creams, incense, and an ingredient in compound preparations like Friar's Balsam
- Skin wounds and scabies
- Cough and respiratory complaints
- As a topical antiseptic
- Fragrance and incense
- Flavoring agent
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Generally used topically or as a flavoring in small amounts, but it can irritate skin and trigger allergic reactions.
Insufficient reliable information available; avoid using.
Read the full pregnancy detailInsufficient reliable information available; avoid using.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Storax (also spelled styrax) is a sticky, sweet-smelling balsam, or resin, that comes from the trunk of certain Liquidambar trees. The most common source is the Oriental sweetgum tree (Liquidambar orientalis), which grows in parts of Turkey and the eastern Mediterranean. A related American species, Liquidambar styraciflua, is also used.
To collect the balsam, the bark is wounded so the tree releases its resin, which is then processed into a thick liquid or semi-solid material. People have used storax for centuries in perfumes, incense, and traditional medicine.
Today storax is mostly found in topical preparations, in fragrance products, and as a flavoring agent. It is also a key ingredient in compound benzoin tincture ("Friar's Balsam"), which is used on the skin.
How it works
Storax contains a mix of aromatic compounds, including cinnamic acid and its esters (such as cinnamyl cinnamate), styrene-related substances, and various resins and balsamic acids. These give it its characteristic smell and may explain some of its proposed effects.
In laboratory settings, some of these compounds appear to have antiseptic, antimicrobial, and mild irritant or warming properties on the skin. The cinnamic acid components are thought to be responsible for much of its antimicrobial activity.
It is important to know that these mechanisms are mostly based on test-tube and animal research. How well they translate into real benefits in the human body is not well established.
Does Storax work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
For Storax, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.
Also studied for 12 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Abdominal pain
Although there has been interest in using oral storax for abdominal pain, there is insufficient reliable information about the clinical effects of storax for this purpose.
Insufficient Reliable Evidence To Rate Amenorrhea
Although there has been interest in using oral storax for amenorrhea, there is insufficient reliable information about the clinical effects of storax for this purpose.
Insufficient Reliable Evidence To Rate Atopic dermatitis (eczema)
Although there has been interest in using topical storax for atopic dermatitis, there is insufficient reliable information about the clinical effects of storax for this purpose.
Insufficient Reliable Evidence To Rate Bronchitis
Although there has been interest in using oral or inhaled storax for bronchitis, there is insufficient reliable information about the clinical effects of storax for this purpose.
Insufficient Reliable Evidence To Rate Cancer
Although there has been interest in using oral storax for cancer, there is insufficient reliable information about the clinical effects of storax for this purpose.
Insufficient Reliable Evidence To Rate Common cold
Although there has been interest in using oral storax for the common cold, there is insufficient reliable information about the clinical effects of storax for this purpose.
Insufficient Reliable Evidence To Rate Cough
Although there has been interest in using oral or inhaled storax for cough, there is insufficient reliable information about the clinical effects of storax for this purpose.
Insufficient Reliable Evidence To Rate Diarrhea
Although there has been interest in using oral storax for diarrhea, there is insufficient reliable information about the clinical effects of storax for this purpose.
Insufficient Reliable Evidence To Rate Epilepsy
Although there has been interest in using oral storax for epilepsy, there is insufficient reliable information about the clinical effects of storax for this purpose.
Insufficient Reliable Evidence To Rate Pharyngitis
Although there has been interest in using oral storax for pharyngitis, there is insufficient reliable information about the clinical effects of storax for this purpose.
Insufficient Reliable Evidence To Rate Scabies
Although there has been interest in using topical storax for scabies, there is insufficient reliable information about the clinical effects of storax for this purpose.
Insufficient Reliable Evidence To Rate Wound healing
Although there has been interest in using topical storax for wound healing, there is insufficient reliable information about the clinical effects of storax for this purpose.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
When used topically in small amounts or as a flavoring, storax is generally considered relatively low-risk for most people. However, it is a resin that can irritate the skin and cause allergic reactions in sensitive individuals.
People with sensitive skin, eczema, or known allergies to balsams, fragrances, or related resins (such as balsam of Peru or benzoin) should be especially careful, as cross-reactions can occur. Avoid getting it in the eyes or on broken or large areas of skin without guidance.
Because there is not enough safety information, pregnant and breastfeeding people should avoid storax. It is also not recommended for use in young children. As with any supplement or herbal product, talk to a pharmacist or doctor before using storax, especially if you have a medical condition or take other medicines.
Side effects
The most common side effects involve the skin, especially when storax is applied directly. These can include:
- Redness, itching, or a rash
- Skin irritation or a burning sensation
- Allergic contact dermatitis in sensitive people
Allergic reactions to balsams are well known, so a patch test on a small area of skin is sensible before wider use. Rarely, a more serious allergic reaction could occur. If you develop a spreading rash, swelling, trouble breathing, or other severe symptoms, stop using it and seek medical care. Swallowing large amounts is not advised and could cause stomach upset or irritation.
Storax: Reported Adverse Effects
Documented safety reports on Storax from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
There is currently a limited amount of information on the adverse effects of sortax. A thorough evaluation of safety outcomes has not been conducted.
Most Common Adverse Effects:
Orally: Diarrhea.
Topically: Allergic reactions, skin sensitization.
Serious Adverse Effects (Rare):
Topically: Nephrotoxicity.
Albuminuria Renal
When applied to large, open wounds, systemic absorption of storax can cause kidney damage (e.g., albuminuria and hemorrhagic nephritis).
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Allergic rhinitis (hay fever) Dermatologic
Topically, storax can cause skin sensitization and contact allergies.
- Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Diarrhea Gastrointestinal
Orally, storax can cause diarrhea.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no well-established standardized dose for storax, and it has not been studied in the kind of rigorous trials needed to recommend specific amounts. It is most often used topically or as a small flavoring ingredient rather than as an oral supplement.
If you use a product that contains storax, follow the directions on the label and do not exceed the recommended amount. Because strength and purity vary between products, it is best to check with a pharmacist or doctor before using it, especially for any medical purpose.
Storax & Pregnancy
Storax & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 2 references that drive our Storax monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Brands that make products with Storax
8 brands in our database make a supplement containing Storax.
Supplement products with Storax
24 products in our database contain Storax. Open any to see its full ingredient list and every drug interaction we check.
Storax: Common Questions
What is Storax used for, and does it work?
Does Storax interact with prescription medications?
How are Storax interactions rated?
Is it safe to take Storax with my medications?
Where does this Storax interaction information come from?
What is Storax used for?
Is Storax safe to use?
Can I use Storax while pregnant or breastfeeding?
Is Storax the same as benzoin or sweetgum?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Products that contain Storax
A rotating sample of real supplements in our database that list Storax — open any to see its full ingredients and every drug interaction we check.
- Kidney Bladder by New Sun
- Essence Chamber by Health Concerns
- Lower Relief by Pacific BioLogic
- S Spleen by Systemic Formulas Bio Function
- Fu Fang Dan Shen Pian CardioVigor 200 mg by Guang Ci Tang
- Frame Builder by Ron Teeguarden's Dragon Herbs
- KB-C by Nature's Sunshine
- Frame Builder by Ron Teeguarden's Dragon Herbs
- KB-C by Nature's Sunshine
- Urinary System by Nature's Sunshine
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