Herb & supplement monograph

Suma Drug Interactions, Uses, Safety & More

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Interaction report

Drugs that interact with Suma

0 medications have a known interaction with Suma, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Suma. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Suma combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Suma: Uses, Safety & Side Effects

The bottom line

Suma is a South American root often marketed as a 'Brazilian ginseng' and used as an adaptogen for energy, stamina, and stress. Human evidence is very limited, and most claims come from traditional use and lab or animal studies. Talk with your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or have a hormone-sensitive condition.

Scientific name
Pfaffia paniculata
Family
Amaranthaceae
Part used
Root
Common forms
Capsules, powder, tablets, tincture, tea
People commonly use it for
  • General energy and vitality
  • Adaptogen for stress
  • Sexual health and libido
  • Athletic performance
  • Immune support
  • Hormonal balance

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Generally used in foods and supplements, but human safety data are limited.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Suma is a large, vine-like ground plant native to the rainforests of Central and South America, especially Brazil. The part used in supplements is the root.

It is sometimes called "Brazilian ginseng," but it is not a true ginseng and is not related to Asian or American ginseng. In traditional medicine, the root has long been used as a tonic to boost energy, support sexual health, and help the body handle stress.

Today Suma is sold as capsules, powders, tablets, tinctures, and teas, often labeled as an adaptogen — a term for herbs claimed to help the body resist physical and mental stress.

Uses & effectiveness

People use Suma for many reasons, including energy, stamina, sexual function, hormone balance, immune support, and recovery from illness or exercise. Most of these uses come from traditional practice, not from strong clinical research.

The scientific evidence in humans is very limited. Much of what is known comes from laboratory and animal studies, which cannot reliably predict how the herb works in people. There are no large, high-quality human trials that clearly show Suma is effective for any specific health condition.

Because the evidence is weak, Suma should be viewed as an unproven supplement. If you are considering it for a specific health problem, talk with a healthcare professional rather than relying on it instead of proven treatments.

How it works

Suma root contains a variety of natural compounds, including plant sterols (such as beta-ecdysterone and sitosterol), saponins sometimes called pfaffosides, amino acids, and minerals.

Researchers have suggested these compounds might have antioxidant, hormone-like, or immune-related effects. Ecdysterone, for example, has been studied for possible effects on muscle and performance.

It is important to know that these proposed mechanisms are mostly based on test-tube and animal research. It is not clear whether they produce meaningful effects in the human body at the amounts found in supplements.

Safety & precautions

Suma has a long history of use as a food and tonic, and it is generally considered reasonably well tolerated for short-term use. However, good-quality human safety studies are lacking, so its long-term safety is not well understood.

Because Suma may have hormone-like activity, people with hormone-sensitive conditions (such as certain breast, uterine, ovarian, or prostate conditions) should be cautious and check with a doctor first.

Inhaling Suma root powder has been linked to asthma-like breathing problems in some people, so handling the dust should be avoided by those with respiratory issues.

Pregnancy and breastfeeding: There is not enough reliable safety information, and the herb may have hormonal effects. To be safe, avoid Suma if you are pregnant, trying to become pregnant, or breastfeeding.

As with any supplement, quality varies between brands. Choose products from reputable manufacturers, and tell your pharmacist or doctor about anything you take.

Side effects

Reported side effects are not well documented because of limited research. Some people may experience mild stomach upset or digestive discomfort.

Breathing in the root powder may trigger asthma symptoms or allergic-type respiratory reactions in sensitive individuals. Allergic reactions are possible with any plant product.

If you develop a rash, trouble breathing, swelling, or other concerning symptoms, stop using Suma and seek medical care.

Suma: Reported Adverse Effects

Documented safety reports on Suma from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, suma seems to be well tolerated. No adverse effects have been reported. However, a thorough evaluation of safety outcomes has not been conducted. When inhaled, powdered suma root can cause occupational asthma.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Foster S, Tyler VE. Tyler's Honest Herbal, 4th ed., Binghamton, NY: Haworth Herbal Press, 1999.
  3. Subiza, J., Subiza, J. L., Escribano, P. M., Hinojosa, M., Garcia, R., Jerez, M., and Subiza, E. Occupational asthma caused by Brazil ginseng dust. J Allergy Clin Immunol 1991;88(5):731-736.
Reports by condition
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no well-established standardized dose for Suma. Studies are too limited to recommend a specific amount, and product strengths vary widely.

If you choose to use it, follow the dosing directions on the product label and do not exceed them. A pharmacist can help you review a product and decide whether it is appropriate for you.

Start low, watch for any reactions, and stop if you notice side effects.

Pregnancy & Breastfeeding

Suma & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Suma & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 3 references that drive our Suma monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Foster S, Tyler VE. Tyler's Honest Herbal, 4th ed., Binghamton, NY: Haworth Herbal Press, 1999. DOI
  3. Subiza, J., Subiza, J. L., Escribano, P. M., Hinojosa, M., Garcia, R., Jerez, M., and Subiza, E. Occupational asthma caused by Brazil ginseng dust. J Allergy Clin Immunol 1991;88(5):731-736. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Product directory

Supplement products with Suma

449 products in our database contain Suma. Open any to see its full ingredient list and every drug interaction we check.

Cleanse For Life Natural Rich Berry by Isagenix Powder 96 Gram(s) · 3.4 oz. View ingredients & interactions CLNZ Chelator by Systemic Formulas Bio Challenge Capsule 60 Capsule(s) View ingredients & interactions Collagen Protein Shake Vanilla flavor by youtheory mens Powder 24 Oz(s) · 680 Gram(s) View ingredients & interactions Complete Multiple Natural Berry Flavor by Liquid Health Liquid 32 fl. Oz. · 946 mL View ingredients & interactions Core Myrrh Blend by Energetix Liquid 2 Fluid Ounce(s) · 59.1 mL View ingredients & interactions Core Myrrh Blend by Energetix Liquid 2 Fluid Ounce(s) · 59.1 mL View ingredients & interactions D-Bal by CrazyBulk Capsule 90 Capsule(s) View ingredients & interactions Daily Start by IVL Capsule 90 Capsule(s) View ingredients & interactions East Star Tincture by Barlow Herbal Liquid 2 Fluid Ounce(s) · 60 mL View ingredients & interactions Echinacea Defense Force 784 mg by Planetary Herbals Tablet Or Pill 90 Tablet(s) View ingredients & interactions Echincea Defense Force by Planetary Herbals Tablet Or Pill 42 Tablet(s) View ingredients & interactions Endo Supreme by Supreme Nutrition Products Capsule 90 Vegetable Capsule(s) View ingredients & interactions Endocrine Daily Tincture by Doctor Morse's Healing Herbs Liquid 2 Ounce(s) · 59 mL View ingredients & interactions Endocrine Glands Capsules by Dr. Morse's Cellular Botanicals Capsule 90 Veggie Cap(s) View ingredients & interactions Endocrine Glands Glycerin by Dr. Morse's Cellular Botanicals Liquid 2 Ounce(s) · 59 Milliliter(s) View ingredients & interactions Endocrine Glands Tincture by Dr. Morse's Cellular Botanicals Liquid 2 Ounce(s) · 59 mL View ingredients & interactions Energize Greens by Holistic Labs Ltd. Powder 253.5 Gram(s) · 0.56 lbs View ingredients & interactions Evotest Grape by BSN Powder 9.41 oz. · 267 Gram(s) View ingredients & interactions Evotest Orange by BSN Powder 9.31 oz. · 264 Gram(s) View ingredients & interactions Eyesight Rx by Advance Physician Formulas Tablet Or Pill 30 Tablet(s) View ingredients & interactions F+ Female Plus by Systemic Formulas Bio Function Capsule 60 Capsule(s) View ingredients & interactions Female Balance Tonic Tincture by Doctor Morse's Healing Herbs Liquid 2 Ounce(s) · 59 mL View ingredients & interactions Female Reproductive Tonic Capsules by Dr. Morse's Cellular Botanicals Capsule 90 Veggiecap(s) View ingredients & interactions Female Reproductive Tonic Tincture by Doctor Morse's Healing Herbs Liquid 2 Ounce(s) · 59 mL View ingredients & interactions
Pharmacist Counseling Corner

Suma: Common Questions

Does Suma interact with prescription medications?
We do not currently list any known drug interactions for Suma. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Suma interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Suma with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Suma interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Suma used for?
Suma is traditionally used as a tonic for energy, stamina, stress, sexual health, and immune support. These are popular uses based on tradition, not proof that it works.
Is Suma the same as ginseng?
No. Suma is sometimes called "Brazilian ginseng," but it is a different plant and is not related to true Asian or American ginseng.
Is Suma safe to take?
It is generally considered reasonably well tolerated for short-term use, but human safety data are limited. People with hormone-sensitive conditions and those who are pregnant or breastfeeding should avoid it or check with a doctor.
Can I take Suma while pregnant or breastfeeding?
It is best to avoid it. There is not enough safety information, and it may have hormone-like effects, so the safe choice is to skip it during pregnancy and breastfeeding.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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