Tormentil Drug Interactions, Uses, Effectiveness, Safety & More
What is this page for?
First and foremost: how Tormentil interacts with medications. The heart of this page is the interaction list — every drug Tormentil is known to interact with, and how serious each one is.
But these pages have grown well beyond that into a full monograph — what Tormentil is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy
Check Tormentil against your medication
Add one medicationDrugs that interact with Tormentil
0 medications have a known interaction with Tormentil, graded by severity. Select any drug for the full evidence-based detail.
We don’t currently list any known drug interactions for Tormentil. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.
What Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each drug listed above links to the full report for that exact Tormentil combination — clinical detail, likelihood, evidence level, and citations.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Tormentil: Uses, Safety & Side Effects
Tormentil is a traditional herb whose root is rich in tannins and has long been used for diarrhea and as a mouth rinse for sore gums or throat. Some small studies suggest it may help shorten diarrhea, but overall evidence is limited and quality is low. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding because safety is not established.
- Scientific name
- Potentilla erecta
- Family
- Rosaceae
- Part used
- Root and rhizome (underground stem)
- Common forms
- Tincture, liquid extract, tea, capsules, mouth rinse
- Diarrhea
- Mouth and throat inflammation
- Mild digestive upset
- Sore throat (gargle)
- Minor wounds and skin irritation
Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.
Generally considered low-risk for short-term use, but human safety data are limited.
Insufficient reliable information available; avoid using.
Read the full pregnancy detailInsufficient reliable information available; avoid using.
Read the full breastfeeding detailPregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Overview
Tormentil (Potentilla erecta) is a small flowering plant in the rose family. It grows across Europe and parts of Asia, often in meadows, heaths, and woodlands. It has bright yellow flowers, but the part used in herbal products is the root and underground stem (rhizome), which has a reddish-brown color inside.
The root is very high in tannins, which give it a strong astringent (drying, tightening) taste. Because of this, tormentil has been used in traditional European herbal medicine for hundreds of years, mainly for diarrhea and for soothing irritated mouths and throats. Today it is sold as a tincture, liquid extract, tea, capsule, or mouth rinse.
How it works
Tormentil root is rich in tannins (such as condensed and hydrolyzable tannins), along with other plant compounds like flavonoids. Tannins are astringent, meaning they bind to proteins and tighten tissues. This is thought to form a protective layer on irritated surfaces, which may reduce fluid loss in the gut and calm inflamed tissue in the mouth or throat.
Laboratory studies suggest tormentil extracts may also have antioxidant, antimicrobial, and antiviral activity, and may calm inflammation. It is important to know that most of these findings come from test-tube or animal research, so they do not prove the same effects happen in the human body.
Does Tormentil work?
How to read these evidence grades
Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.
For Tormentil, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.
Also studied for 2 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Rotaviral diarrhea
It is unclear if oral tormentil root extract is beneficial in children with rotaviral diarrhea.
Insufficient Reliable Evidence To Rate Ulcerative colitis
It is unclear if oral tormentil extract is beneficial in patients with ulcerative colitis.
Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.
Safety & precautions
Tormentil is generally considered low-risk for short-term use in adults when used as directed. However, human safety data are limited, so caution is wise. Because the root is high in tannins, large amounts or long-term use could irritate the stomach.
People with stomach or bowel conditions should check with a healthcare provider first. Diarrhea that is severe, bloody, lasts more than a couple of days, or comes with high fever needs medical attention rather than self-treatment with an herb.
Pregnancy and breastfeeding: There is not enough reliable safety information for these situations. To be safe, avoid tormentil if you are pregnant or breastfeeding. Always speak with your pharmacist or doctor before giving any herbal product to children.
Side effects
Tormentil is usually well tolerated for short-term use. The most likely side effects come from its high tannin content and may include stomach upset, nausea, or constipation, especially with larger doses. Some people may find the strong astringent taste unpleasant.
Allergic reactions are possible but uncommon. Stop using it and seek medical care if you notice rash, swelling, or trouble breathing. If symptoms get worse or do not improve, contact a healthcare provider.
Tormentil: Reported Adverse Effects
Documented safety reports on Tormentil from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.
Orally, tormentil seems to be well tolerated.
Most Common Adverse Effects:
Orally: Abdominal pain, heartburn, and a feeling of fullness.
Dyspepsia Gastrointestinal
Orally, tormentil has been reported to cause mild abdominal pain, heartburn, and feelings of fullness in one clinical trial. These adverse effects occurred at the same frequency for doses ranging from 1.2 grams daily to 3 grams daily.
Adverse-effects data: Natural Medicines, Therapeutic Research Center
Dosing
There is no official, standardized dose for tormentil, and products vary widely in strength. Tinctures, extracts, teas, and capsules will each have different recommended amounts.
The safest approach is to follow the directions on the product label and not exceed them. Because doses and product quality differ, check with your pharmacist or doctor before starting, and use it only for a short period. If you are using it as a mouth rinse, do not swallow large amounts.
Tormentil & Pregnancy
Tormentil & Breastfeeding
© 2026 Therapeutic Research Center
Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center
References & further reading
The 1 references that drive our Tormentil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Huber, R., Ditfurth, A. V., Amann, F., Guthlin, C., Rostock, M., Trittler, R., Kummerer, K., and Merfort, I. Tormentil for active ulcerative colitis: an open-label, dose-escalating study. J.Clin.Gastroenterol. 2007;41(9):834-838. PubMed
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Tormentil: Common Questions
What is Tormentil used for, and does it work?
Does Tormentil interact with prescription medications?
How are Tormentil interactions rated?
Is it safe to take Tormentil with my medications?
Where does this Tormentil interaction information come from?
What is Tormentil used for?
Does Tormentil actually work for diarrhea?
Is Tormentil safe to take?
Can I use Tormentil during pregnancy or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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