Herb & supplement monograph

Tormentil Drug Interactions, Uses, Effectiveness, Safety & More

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Interaction report

Drugs that interact with Tormentil

0 medications have a known interaction with Tormentil, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Tormentil. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Tormentil combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Tormentil: Uses, Safety & Side Effects

The bottom line

Tormentil is a traditional herb whose root is rich in tannins and has long been used for diarrhea and as a mouth rinse for sore gums or throat. Some small studies suggest it may help shorten diarrhea, but overall evidence is limited and quality is low. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding because safety is not established.

Scientific name
Potentilla erecta
Family
Rosaceae
Part used
Root and rhizome (underground stem)
Common forms
Tincture, liquid extract, tea, capsules, mouth rinse
People commonly use it for
  • Diarrhea
  • Mouth and throat inflammation
  • Mild digestive upset
  • Sore throat (gargle)
  • Minor wounds and skin irritation

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Generally considered low-risk for short-term use, but human safety data are limited.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Tormentil (Potentilla erecta) is a small flowering plant in the rose family. It grows across Europe and parts of Asia, often in meadows, heaths, and woodlands. It has bright yellow flowers, but the part used in herbal products is the root and underground stem (rhizome), which has a reddish-brown color inside.

The root is very high in tannins, which give it a strong astringent (drying, tightening) taste. Because of this, tormentil has been used in traditional European herbal medicine for hundreds of years, mainly for diarrhea and for soothing irritated mouths and throats. Today it is sold as a tincture, liquid extract, tea, capsule, or mouth rinse.

How it works

Tormentil root is rich in tannins (such as condensed and hydrolyzable tannins), along with other plant compounds like flavonoids. Tannins are astringent, meaning they bind to proteins and tighten tissues. This is thought to form a protective layer on irritated surfaces, which may reduce fluid loss in the gut and calm inflamed tissue in the mouth or throat.

Laboratory studies suggest tormentil extracts may also have antioxidant, antimicrobial, and antiviral activity, and may calm inflammation. It is important to know that most of these findings come from test-tube or animal research, so they do not prove the same effects happen in the human body.

Effectiveness

Does Tormentil work?

Evidence overview · 2 uses evaluated
2 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Tormentil, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 2 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Rotaviral diarrhea
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral tormentil root extract is beneficial in children with rotaviral diarrhea.

Insufficient Reliable Evidence To Rate Ulcerative colitis
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral tormentil extract is beneficial in patients with ulcerative colitis.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

Tormentil is generally considered low-risk for short-term use in adults when used as directed. However, human safety data are limited, so caution is wise. Because the root is high in tannins, large amounts or long-term use could irritate the stomach.

People with stomach or bowel conditions should check with a healthcare provider first. Diarrhea that is severe, bloody, lasts more than a couple of days, or comes with high fever needs medical attention rather than self-treatment with an herb.

Pregnancy and breastfeeding: There is not enough reliable safety information for these situations. To be safe, avoid tormentil if you are pregnant or breastfeeding. Always speak with your pharmacist or doctor before giving any herbal product to children.

Side effects

Tormentil is usually well tolerated for short-term use. The most likely side effects come from its high tannin content and may include stomach upset, nausea, or constipation, especially with larger doses. Some people may find the strong astringent taste unpleasant.

Allergic reactions are possible but uncommon. Stop using it and seek medical care if you notice rash, swelling, or trouble breathing. If symptoms get worse or do not improve, contact a healthcare provider.

Tormentil: Reported Adverse Effects

Documented safety reports on Tormentil from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, tormentil seems to be well tolerated.

Most Common Adverse Effects:

Orally: Abdominal pain, heartburn, and a feeling of fullness.

Reports by condition
Dyspepsia Gastrointestinal

Orally, tormentil has been reported to cause mild abdominal pain, heartburn, and feelings of fullness in one clinical trial. These adverse effects occurred at the same frequency for doses ranging from 1.2 grams daily to 3 grams daily.

  1. Huber, R., Ditfurth, A. V., Amann, F., Guthlin, C., Rostock, M., Trittler, R., Kummerer, K., and Merfort, I. Tormentil for active ulcerative colitis: an open-label, dose-escalating study. J.Clin.Gastroenterol. 2007;41(9):834-838.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no official, standardized dose for tormentil, and products vary widely in strength. Tinctures, extracts, teas, and capsules will each have different recommended amounts.

The safest approach is to follow the directions on the product label and not exceed them. Because doses and product quality differ, check with your pharmacist or doctor before starting, and use it only for a short period. If you are using it as a mouth rinse, do not swallow large amounts.

Pregnancy & Breastfeeding

Tormentil & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Tormentil & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 1 references that drive our Tormentil monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Huber, R., Ditfurth, A. V., Amann, F., Guthlin, C., Rostock, M., Trittler, R., Kummerer, K., and Merfort, I. Tormentil for active ulcerative colitis: an open-label, dose-escalating study. J.Clin.Gastroenterol. 2007;41(9):834-838. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Pharmacist Counseling Corner

Tormentil: Common Questions

What is Tormentil used for, and does it work?
People use Tormentil for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Tormentil interact with prescription medications?
We do not currently list any known drug interactions for Tormentil. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Tormentil interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Tormentil with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Tormentil interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Tormentil used for?
It is most commonly used for diarrhea and as a gargle or rinse for sore, inflamed mouths and throats. It is also used traditionally for minor stomach upset and skin irritation, though strong evidence is limited.
Does Tormentil actually work for diarrhea?
A few small studies suggest a Tormentil root extract may shorten diarrhea, but the evidence is preliminary and not high quality. Severe, bloody, or long-lasting diarrhea should be evaluated by a doctor.
Is Tormentil safe to take?
It is generally considered low-risk for short-term use in adults, but human safety data are limited. Its high tannin content can cause stomach upset, so use it as directed and check with your pharmacist first.
Can I use Tormentil during pregnancy or breastfeeding?
No reliable safety information is available for these situations, so it is best to avoid Tormentil if you are pregnant or breastfeeding.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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