Herb & supplement monograph

Yoga Drug Interactions, Uses, Effectiveness, Safety & More

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Interaction report

Drugs that interact with Yoga

0 medications have a known interaction with Yoga, graded by severity. Select any drug for the full evidence-based detail.

We don’t currently list any known drug interactions for Yoga. This doesn’t guarantee none exist — always confirm with your pharmacist before combining supplements with your medications.

Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Yoga combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Monograph

Yoga: Uses, Safety & Side Effects

The bottom line

Yoga is a mind-body practice combining physical postures, breathing techniques, and meditation, not a dietary supplement or herb. Research suggests it may help with stress, back pain, mood, and overall well-being, and it is generally safe for most people when practiced carefully. Beginners and those with health conditions should start gently and talk to a doctor before beginning.

Part used
Not applicable (mind-body practice)
Common forms
Hatha yoga, Vinyasa, Iyengar, restorative yoga, breathing exercises (pranayama), meditation classes, online videos, group or private sessions
People commonly use it for
  • Stress and anxiety
  • Low back pain
  • Flexibility and balance
  • Sleep problems
  • Depression and mood
  • General wellness and fitness

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallLikely safe

Generally safe for most people when practiced appropriately and within personal limits.

PregnancyPossibly Safe

When used appropriately. Some clinical research shows that yoga during pregnancy does not adversely affect birth outcomes. However, some aggressive fo...

Read the full pregnancy detail
BreastfeedingPossibly Safe

When used appropriately. Some clinical research shows that yoga during pregnancy does not adversely affect birth outcomes. However, some aggressive fo...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Yoga is not a herb or dietary supplement. It is a mind-body practice that began thousands of years ago in ancient India. The word "yoga" comes from a term meaning to join or unite, reflecting the idea of connecting the body, breath, and mind.

Modern yoga usually combines three main parts: physical postures (called asanas), breathing exercises (called pranayama), and meditation or relaxation. There are many styles, ranging from gentle and slow (such as restorative or Hatha yoga) to fast and physically demanding (such as Vinyasa or power yoga).

Today, people around the world practice yoga in studios, gyms, homes, and online. Many use it for fitness, stress relief, and overall well-being.

How it works

Yoga is thought to work through several connected pathways rather than a single active ingredient. The physical postures gently stretch and strengthen muscles, which may improve flexibility, balance, and posture.

The breathing and meditation parts may calm the body's stress response. Researchers believe yoga can help shift the nervous system toward a more relaxed state, which may lower heart rate, ease muscle tension, and reduce feelings of stress. Some studies have measured changes in stress hormones and markers of inflammation, though these findings are still being explored.

Much of this is based on smaller studies, and the exact mechanisms are not fully understood. The combination of movement, breath, and focused attention likely contributes to its overall effects.

Effectiveness

Does Yoga work?

Evidence overview · 80 uses evaluated
10 Possibly effective 70 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.
Possibly Effective Asthma
Rating & evidence shown verbatim from Natural Medicines

Yoga appears to slightly improve symptoms and quality of life in patients with asthma. The effectiveness of yogic breathing exercises (pranayama) specifically is less clear.

Possibly Effective Back pain
Rating & evidence shown verbatim from Natural Medicines

Yoga seems to alleviate pain in some patients with chronic low back pain.

Possibly Effective Breast cancer
Rating & evidence shown verbatim from Natural Medicines

Yoga seems to be beneficial in patients with breast cancer, with effects comparable to other exercise regimens.

Possibly Effective Cancer-related fatigue
Rating & evidence shown verbatim from Natural Medicines

Yoga seems to be beneficial in patients with cancer-related fatigue.

Possibly Effective Cardiovascular disease (CVD)
Rating & evidence shown verbatim from Natural Medicines

Yoga, alone or in combination with other lifestyle changes, appears to improve risk factors for CVD. However, evidence in patients with established coronary artery disease (CAD) is mixed.

Possibly Effective Diabetes
Rating & evidence shown verbatim from Natural Medicines

Yoga seems to modestly improve glycemic control in patients with type 2 diabetes.

Possibly Effective Menopausal symptoms
Rating & evidence shown verbatim from Natural Medicines

Yoga seems to help alleviate menopausal symptoms, with beneficial effects comparable to other exercise interventions.

Possibly Effective Neck pain
Rating & evidence shown verbatim from Natural Medicines

Yoga seems to alleviate neck pain and disability due to neck pain.

Possibly Effective Schizophrenia
Rating & evidence shown verbatim from Natural Medicines

Yoga seems to improve symptoms, social functioning, and quality of life in patients with schizophrenia; however, yoga may not be more effective than other forms of exercise.

Possibly Effective Tuberculosis
Rating & evidence shown verbatim from Natural Medicines

When combined with anti-tuberculosis therapy, yoga seems to improve symptoms, weight, and some measures of lung function.

Also studied for 70 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Abdominal pain
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial for abdominal pain in children.

Insufficient Reliable Evidence To Rate Adjustment disorders
Rating & evidence shown verbatim from Natural Medicines

Yoga has only been evaluated in combination with massage in children with adjustment disorder; its effect when used alone is unclear.

Insufficient Reliable Evidence To Rate Age-related cognitive decline
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial for age-related cognitive decline.

Insufficient Reliable Evidence To Rate Alcohol use disorder
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with alcohol use disorder.

Insufficient Reliable Evidence To Rate Altitude sickness
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with altitude sickness.

Insufficient Reliable Evidence To Rate Aromatase inhibitor-induced arthralgia
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in survivors of breast cancer with aromatase-induced arthralgia.

Insufficient Reliable Evidence To Rate Athletic performance
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga improves athletic performance.

Insufficient Reliable Evidence To Rate Attention deficit-hyperactivity disorder (ADHD)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in children with ADHD.

Insufficient Reliable Evidence To Rate Autism spectrum disorder
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in children with autism spectrum disorder.

Insufficient Reliable Evidence To Rate Bronchitis
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with chronic bronchitis.

Insufficient Reliable Evidence To Rate Cancer-related pain
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with cancer-related pain.

Insufficient Reliable Evidence To Rate Carpal tunnel syndrome
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with carpal tunnel syndrome.

Insufficient Reliable Evidence To Rate Cerebral palsy
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in children with cerebral palsy.

Insufficient Reliable Evidence To Rate Chemotherapy-induced nausea and vomiting (CINV)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with CINV.

Insufficient Reliable Evidence To Rate Chemotherapy-induced peripheral neuropathy
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in survivors of cancer with chemotherapy-induced peripheral neuropathy.

Insufficient Reliable Evidence To Rate Chemotherapy-related fatigue
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with chemotherapy-related fatigue.

Insufficient Reliable Evidence To Rate Chest trauma
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with blunt chest trauma.

Insufficient Reliable Evidence To Rate Chronic fatigue syndrome (CFS)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with CFS.

Insufficient Reliable Evidence To Rate Chronic kidney disease (CKD)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with CKD undergoing dialysis.

Insufficient Reliable Evidence To Rate Chronic obstructive pulmonary disease (COPD)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with COPD.

Insufficient Reliable Evidence To Rate Cognitive function
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial for improving cognitive function in healthy children and adults.

Insufficient Reliable Evidence To Rate Cognitive impairment
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with mild cognitive impairment.

Insufficient Reliable Evidence To Rate Coronary artery bypass graft (CABG) surgery
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients undergoing rehabilitation following CABG surgery.

Insufficient Reliable Evidence To Rate Coronavirus disease 2019 (COVID-19)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial for hospitalized patients with COVID-19.

Insufficient Reliable Evidence To Rate Dyslexia
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using yoga for dyslexia, there is insufficient reliable information about the clinical effects of yoga for this purpose.

Insufficient Reliable Evidence To Rate Dysmenorrhea
Rating & evidence shown verbatim from Natural Medicines

Small clinical studies suggest that yoga may improve menstrual pain in patients with primary dysmenorrhea.

Insufficient Reliable Evidence To Rate Epilepsy
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with epilepsy.

Insufficient Reliable Evidence To Rate Fibromyalgia
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with fibromyalgia.

Insufficient Reliable Evidence To Rate Generalized anxiety disorder (GAD)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with GAD.

Insufficient Reliable Evidence To Rate Glaucoma
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with glaucoma.

Insufficient Reliable Evidence To Rate Head and neck cancer
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in survivors of head and neck cancer.

Insufficient Reliable Evidence To Rate Heart failure
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with heart failure.

Insufficient Reliable Evidence To Rate HIV/AIDS
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with HIV/AIDS.

Insufficient Reliable Evidence To Rate Insomnia
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with insomnia.

Insufficient Reliable Evidence To Rate Intellectual disability
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in children with intellectual disability.

Insufficient Reliable Evidence To Rate Irritable bowel syndrome (IBS)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with IBS.

Insufficient Reliable Evidence To Rate Labor pain
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial for labor pain.

Insufficient Reliable Evidence To Rate Lymphedema
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with breast-cancer related lymphedema.

Insufficient Reliable Evidence To Rate Metabolic syndrome
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with metabolic syndrome.

Insufficient Reliable Evidence To Rate Migraine headache
Rating & evidence shown verbatim from Natural Medicines

Small studies suggest that yoga may improve frequency, intensity, and pain in patients with migraine.

Insufficient Reliable Evidence To Rate Multiple sclerosis (MS)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with MS.

Insufficient Reliable Evidence To Rate Muscle soreness
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga improves muscle soreness.

Insufficient Reliable Evidence To Rate Myocardial infarction (MI)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial as part of cardiac rehabilitation in patients receiving conservative medical management for a recent MI.

Insufficient Reliable Evidence To Rate Obesity
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga improves weight loss in adults or children with overweight or obesity.

Insufficient Reliable Evidence To Rate Obsessive-compulsive disorder (OCD)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with OCD.

Insufficient Reliable Evidence To Rate Opioid withdrawal
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with opioid use disorder receiving maintenance therapy.

Insufficient Reliable Evidence To Rate Osteoarthritis
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with osteoarthritis.

Insufficient Reliable Evidence To Rate Osteoporosis
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using yoga for osteoporosis, there is insufficient reliable information about the clinical effects of yoga for this purpose.

Insufficient Reliable Evidence To Rate Pancreatitis
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with chronic pancreatitis.

Insufficient Reliable Evidence To Rate Parkinson disease
Rating & evidence shown verbatim from Natural Medicines

Small meta-analyses suggest that yoga may improve some motor and nonmotor symptoms in patients with Parkinson disease.

Insufficient Reliable Evidence To Rate Physical performance
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial for physical performance in older adults.

Insufficient Reliable Evidence To Rate Polycystic ovary syndrome (PCOS)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with PCOS.

Insufficient Reliable Evidence To Rate Post-traumatic stress disorder (PTSD)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial for patients with PTSD.

Insufficient Reliable Evidence To Rate Postoperative pain
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial for reducing postoperative pain.

Insufficient Reliable Evidence To Rate Postoperative recovery
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial for postoperative recovery following hip surgery.

Insufficient Reliable Evidence To Rate Postpartum depression
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial for patients with postpartum depression.

Insufficient Reliable Evidence To Rate Pre-eclampsia
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial for preventing pre-eclampsia.

Insufficient Reliable Evidence To Rate Pregnancy-induced hypertension
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with third trimester pregnancy-induced mild hypertension.

Insufficient Reliable Evidence To Rate Premature ejaculation
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with premature ejaculation.

Insufficient Reliable Evidence To Rate Premenstrual syndrome (PMS)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with PMS.

Insufficient Reliable Evidence To Rate Preterm labor
Rating & evidence shown verbatim from Natural Medicines

Small studies suggest yoga is beneficial for preventing preterm labor.

Insufficient Reliable Evidence To Rate Psychosis
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with psychosis.

Insufficient Reliable Evidence To Rate Quality of life
Rating & evidence shown verbatim from Natural Medicines

Small clinical studies suggest that yoga improves quality of life.

Insufficient Reliable Evidence To Rate Rheumatoid arthritis (RA)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with RA.

Insufficient Reliable Evidence To Rate Scoliosis
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with scoliosis.

Insufficient Reliable Evidence To Rate Seasonal affective disorder (SAD)
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using yoga for SAD, there is insufficient reliable information about the clinical effects of yoga for this purpose.

Insufficient Reliable Evidence To Rate Stroke
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with stroke.

Insufficient Reliable Evidence To Rate Syncope
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with syncope.

Insufficient Reliable Evidence To Rate Tinnitus
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in patients with chronic idiopathic tinnitus.

Insufficient Reliable Evidence To Rate Urinary incontinence
Rating & evidence shown verbatim from Natural Medicines

It is unclear if yoga is beneficial in older females with stress or mixed urinary incontinence.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

For most healthy people, yoga is considered safe when practiced with proper instruction and within your own limits. Choosing a qualified instructor and starting slowly can lower the risk of injury.

People with certain conditions should be careful or talk to a doctor first. This includes those with glaucoma, uncontrolled high blood pressure, osteoporosis, recent surgery, balance problems, or joint and back injuries. Some intense styles, such as hot yoga, can cause overheating or dehydration and may not be right for everyone.

During pregnancy, prenatal yoga can be beneficial, but certain poses—especially deep twists, lying flat on the back later in pregnancy, and intense abdominal work—should be avoided. Always check with your healthcare provider first. Breastfeeding mothers can generally practice gentle yoga safely.

Side effects

Yoga is generally well tolerated. The most common problems are muscle soreness or strains, especially in beginners or those who push too hard into a pose.

More serious injuries are uncommon but can happen, such as joint, neck, or back injuries from advanced or improper postures. Inversions (poses where the head is below the heart) may not be suitable for people with certain eye, neck, or blood pressure conditions.

To stay safe, move gently, avoid forcing a stretch, and stop if you feel sharp pain, dizziness, or shortness of breath.

Yoga: Reported Adverse Effects

Documented safety reports on Yoga from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Yoga is generally safe and well tolerated.

Most Common Adverse Effects:

Temporary musculoskeletal pain.

Serious Adverse Effects (Rare):

Cerebral hemorrhage, chronic back, neck, shoulder, knee, or hip pain, chronic headache, fractures, sciatica, strains and sprains, and tendon shortening. Hot yoga has been reported to cause heat stroke. Yoga techniques involving aggressive breathing have been associated with pneumothorax and subcutaneous emphysema.

Reports by condition
Cardiac arrest Cardiovascular

A 35-year-old adult at 12 weeks postpartum was admitted to the emergency room for hyperthermia, or heat stroke, from practicing hot yoga. The heat stroke resulted in ventricular fibrillation and cardiac arrest requiring cardiopulmonary resuscitation and supportive care.

  1. Boddu P, Patel S, Shahrrava A. Sudden Cardiac Arrest From Heat Stroke: Hidden Dangers of Hot Yoga. Am J Med. 2016;129(8):e129-30.
Chronic obstructive pulmonary disease (COPD) Pulmonary/Respiratory

A 40-year-old adult experienced subcutaneous emphysema following an aggressive yoga exercise called "pranayam". This exercise involves using the Valsalva maneuver. In another case, a 29-year-old adult experienced pneumothorax following an aggressive yoga breathing technique called "Kapalabhati pranayama", also known as "breath of fire" or "skull shining breath".

  1. Kashyap AS, Anand KP, Kashyap S. Complications of yoga. Emerg Med J 2007;24:231.
  2. Johnson DB, Tierney MJ, Sadighi PJ. Kapalabhati pranayama: breath of fire or cause of pneumothorax? A case report. Chest 2004;125:1951-2.
Cluster headache Neurologic/CNS

Chronic headache, sleep problems, cerebral hemorrhage, tingling, vertigo, and depressive symptoms have all been reported rarely by individuals practicing yoga. A case of acute cervical myelopathy with concurrent cervical arterial dissection is reported in a 63-year-old after performing the Vrischikasana yoga pose. The patient was hospitalized and recovered gradually following surgery and antithrombotic treatment.

  1. Cramer H, Quinker D, Schumann D, Wardle J, Dobos G, Lauche R. Adverse effects of yoga: a national cross-sectional survey. BMC Complement Altern Med. 2019 Jul 29;19(1):190. doi: 10.1186/s12906-019-2612-7.
  2. Simon NM, Hofmann SG, Rosenfield D, et al. Efficacy of yoga vs cognitive behavioral therapy vs stress education for the treatment of generalized anxiety disorder: A randomized clinical trial. JAMA Psychiatry. 2021;78(1):13-20.
  3. Nayar G, Desai A, Agarwal N, Alan N, Moossy JJ. Cervical arterial dissection and traumatic myelopathy following yoga: surgical case report. Spinal Cord Ser Cases 2022;8(1):46.
Fractures Musculoskeletal

Like other physical exercises, yoga can cause or worsen musculoskeletal pain. A retrospective study found that practicing yoga recreationally is associated with worsened musculoskeletal pain in the wrist and hand. Musculoskeletal injuries are most commonly associated with power yoga, the use of props, and employing hand-, shoulder-, and head-stands, as well as forward and backward bends and sitting positions. Chronic back, neck, shoulder, knee, or hip pain, tendon shortening, ligament rupture, strains and sprains, fractures, and sciatica have all been rarely reported.

  1. Wieland LS, Skoetz N, Pilkington K, Vempati R, D'Adamo CR, Berman BM. Yoga treatment for chronic non-specific low back pain. Cochrane Database Syst Rev. 2017;1:CD010671.
  2. Schmid AA, Fruhauf CA, Sharp JL, Van Puymbroeck MV, Bair MJ, Portz JD. Yoga for People With Chronic Pain in a Community-Based Setting: A Feasibility and Pilot RCT. J Evid Based Integr Med. 2019 Jan-Dec;24:2515690X19863763. doi: 10.1177/2515690X19863763.
  3. Simon NM, Hofmann SG, Rosenfield D, et al. Efficacy of yoga vs cognitive behavioral therapy vs stress education for the treatment of generalized anxiety disorder: A randomized clinical trial. JAMA Psychiatry. 2021;78(1):13-20.
  4. Zhu F, Zhang M, Wang D, Hong Q, Zeng C, Chen W. Yoga compared to non-exercise or physical therapy exercise on pain, disability, and quality of life for patients with chronic low back pain: A systematic review and meta-analysis of randomized controlled tri
  5. Campo M, Shiyko MP, Kean MB, Roberts L, Pappas E. Musculoskeletal pain associated with recreational yoga participation: A prospective cohort study with 1-year follow-up, Journal of Bodywork & Movement Therapies (2017).
  6. Cramer H, Quinker D, Schumann D, Wardle J, Dobos G, Lauche R. Adverse effects of yoga: a national cross-sectional survey. BMC Complement Altern Med. 2019 Jul 29;19(1):190. doi: 10.1186/s12906-019-2612-7.
  7. Wiese C, Keil D, Rasmussen AS, Olesen R. Injury in yoga asana practice: Assessment of the risks. J Bodyw Mov Ther. 2019 Jul;23(3):479-488. doi: 10.1016/j.jbmt.2018.09.151. Epub 2018 Oct 24.
  8. Wu T, Yan F, Wei Y, et al. Effect of Exercise Therapy on Cancer-Related Fatigue in Patients With Breast Cancer: A Systematic Review and Network Meta-analysis. Am J Phys Med Rehabil 2023;102(12):1055-1062.
  9. Ko KY, Kwok ZCM, Chan HY. Effects of yoga on physical and psychological health among community-dwelling older adults: A systematic review and meta-analysis. Int J Older People Nurs 2023;18(5):e12562.
  10. El Alam AE, Otayek JN, Ghanimeh JG, El Karaaoui JM, Semaan SF, Pierre Khoury A. An isolated rupture of the anterolateral ligament of the knee: A case report. Medicine (Baltimore) 2023;102(28):e34259.
Glaucoma Ocular/Otic

In patients with glaucoma, intraocular pressure has been reported to increase during the practice of inversion asanas or head-down yoga poses such as headstand, downward facing dog, standing forward bend, plough, and legs up the wall.

  1. Chetry D, Singh J, Chhetri A, Katiyar VK, Singh DS. Effect of yoga on intra-ocular pressure in patients with glaucoma: A systematic review and meta-analysis. Indian J Ophthalmol 2023;71(5):1757-1765.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no standard "dose" for yoga the way there is for a supplement. Benefits often come from regular, ongoing practice rather than a single session.

Many studies use sessions lasting from about 30 to 90 minutes, practiced once or several times per week. A good approach is to start with shorter, gentler sessions and gradually build up as your comfort and ability improve.

If you are new to yoga or have a health condition, consider working with a qualified instructor and checking with your doctor or pharmacist to make sure your chosen style is appropriate for you.

Pregnancy & Breastfeeding
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 19 references that drive our Yoga monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Chuntharapat S, Petpichetchian W, Hatthakit U. Yoga during pregnancy: effects on maternal comfort, labor pain and birth outcomes. Complement Ther Clin Pract 2008;14:105-15. PubMed
  2. Narendran S, Nagarathna R, Narendran V, et al. Efficacy of yoga on pregnancy outcome. J Altern Complement Med 2005;11:237-44. PubMed
  3. Kashyap AS, Anand KP, Kashyap S. Complications of yoga. Emerg Med J 2007;24:231. PubMed
  4. Johnson DB, Tierney MJ, Sadighi PJ. Kapalabhati pranayama: breath of fire or cause of pneumothorax? A case report. Chest 2004;125:1951-2. PubMed
  5. Boddu P, Patel S, Shahrrava A. Sudden Cardiac Arrest From Heat Stroke: Hidden Dangers of Hot Yoga. Am J Med. 2016;129(8):e129-30.
  6. Campo M, Shiyko MP, Kean MB, Roberts L, Pappas E. Musculoskeletal pain associated with recreational yoga participation: A prospective cohort study with 1-year follow-up, Journal of Bodywork & Movement Therapies (2017). PubMed
  7. Wieland LS, Skoetz N, Pilkington K, Vempati R, D'Adamo CR, Berman BM. Yoga treatment for chronic non-specific low back pain. Cochrane Database Syst Rev. 2017;1:CD010671. DOI
  8. Schmid AA, Fruhauf CA, Sharp JL, Van Puymbroeck MV, Bair MJ, Portz JD. Yoga for People With Chronic Pain in a Community-Based Setting: A Feasibility and Pilot RCT. J Evid Based Integr Med. 2019 Jan-Dec;24:2515690X19863763. doi: 10.1177/2515690X19863763. PubMed
  9. Cramer H, Quinker D, Schumann D, Wardle J, Dobos G, Lauche R. Adverse effects of yoga: a national cross-sectional survey. BMC Complement Altern Med. 2019 Jul 29;19(1):190. doi: 10.1186/s12906-019-2612-7. PubMed
  10. Wiese C, Keil D, Rasmussen AS, Olesen R. Injury in yoga asana practice: Assessment of the risks. J Bodyw Mov Ther. 2019 Jul;23(3):479-488. doi: 10.1016/j.jbmt.2018.09.151. Epub 2018 Oct 24. PubMed
  11. Simon NM, Hofmann SG, Rosenfield D, et al. Efficacy of yoga vs cognitive behavioral therapy vs stress education for the treatment of generalized anxiety disorder: A randomized clinical trial. JAMA Psychiatry. 2021;78(1):13-20. PubMed
  12. Zhu F, Zhang M, Wang D, Hong Q, Zeng C, Chen W. Yoga compared to non-exercise or physical therapy exercise on pain, disability, and quality of life for patients with chronic low back pain: A systematic review and meta-analysis of randomized controlled tri
  13. Makhija A, Khatik N, Raghunandan C. A randomized control trial to study the effect of integrated yoga on pregnancy outcome in hypertensive disorder of pregnancy. Complement Ther Clin Pract. 2021;43:101366. PubMed
  14. Pais M, Pai MV, Kamath A, Bhat R, Bhat P, Joisa GH. A Randomized Controlled Trial on the Efficacy of Integrated Yoga on Pregnancy Outcome. Holist Nurs Pract 2021;35(5):273-280. PubMed
  15. Nayar G, Desai A, Agarwal N, Alan N, Moossy JJ. Cervical arterial dissection and traumatic myelopathy following yoga: surgical case report. Spinal Cord Ser Cases 2022;8(1):46. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Pharmacist Counseling Corner

Yoga: Common Questions

What is Yoga used for, and does it work?
People use Yoga for many reasons, but the evidence varies by use. According to the Natural Medicines database, there is at least some clinical evidence supporting Yoga for Asthma, Back pain, Breast cancer and Cancer-related fatigue. For most other uses it has been studied for, the evidence is currently insufficient to rate. See the graded list on this page, and always confirm with your pharmacist or doctor.
Does Yoga interact with prescription medications?
We do not currently list any known drug interactions for Yoga. This does not guarantee that none exist, so always confirm with your pharmacist before combining it with your medications.
How are Yoga interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Yoga with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Yoga interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
Is Yoga a good form of exercise?
Yes. Yoga can improve flexibility, strength, and balance, and may help with stress and overall well-being. The intensity varies a lot by style, so you can choose one that fits your fitness level.
Do I need to be flexible to start Yoga?
No. Flexibility tends to develop over time with practice. Beginners can start with gentle classes and modify poses as needed.
Can Yoga help with stress and anxiety?
Many people find Yoga calming, and research suggests it may help reduce stress, anxiety, and improve mood. It works best alongside, not instead of, other recommended treatments for anxiety or depression.
Is Yoga safe during pregnancy?
Prenatal Yoga can be helpful, but some poses should be avoided and you should check with your doctor or midwife before starting. Look for classes designed specifically for pregnancy.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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