100% Pure Glycine Ingredients & Drug Interactions
by NutraBio
What is this page for?
First and foremost: checking 100% Pure Glycine against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
100% Pure Glycine is a dietary supplement by NutraBio with 1 active ingredient. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against 100% Pure Glycine by NutraBio
Ask about any prescription or over-the-counter medication and we check it for interactions with 100% Pure Glycine by NutraBio — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of 100% Pure Glycine by NutraBio
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product is straightforward: it's a single active ingredient, glycine, in powder form with no fillers or other inactive ingredients. Glycine is an amino acid your body makes naturally and uses in protein synthesis and nervous system function.
The supplement provides pure glycine in a simple, no-nonsense format.
Does it work?
Moderate evidence
The evidence for glycine is mixed depending on what you're using it for. For schizophrenia, it's rated possibly effective — meaning there's some clinical support, though it's not a first-line treatment and works best as an add-on to other medications under medical supervision.
For 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency, attention deficit-hyperactivity disorder (ADHD), benign prostatic hyperplasia (BPH), and cystic fibrosis, the evidence isn't established well enough for us to rate it. If you're considering glycine for one of those conditions, your doctor can help weigh what we know.
How safe is it?
Well-documented data
Glycine is generally well tolerated at typical doses, though long-term safety data are limited. The most common side effects are mild and rare — a small number of people report mild sedation, soft stools, nausea, vomiting, or upper stomach discomfort that goes away quickly when you stop taking it.
Irritability, insomnia, fatigue, memory problems, headache, dry mouth, and sensory changes have been reported, but we're not certain they're caused by glycine itself. For pregnancy and breastfeeding, we don't hold enough safety data to say either way — talk with your doctor or pharmacist for personalized guidance on whether it's right for you.
Meds to double-check
Moderate interaction found
If you take clozapine (Clozaril) for schizophrenia, don't add glycine without checking with your doctor or pharmacist first — it may make the medication less effective. That's the only medication-type interaction we have documented for this ingredient.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This is a simple, single-ingredient supplement. If you take clozapine for schizophrenia, check with your pharmacist or doctor before starting — glycine may interfere with how well it works.
For other uses, the evidence is limited or still being studied. A pharmacist can help you figure out if it's the right fit.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about 100% Pure Glycine, straight from the product label.
| Brand | NutraBio |
|---|---|
| Barcode (UPC) | 649908232108 |
| Net contents | 500 Gram(s); 1.1 lbs |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2015 |
| DSLD ID | 50838 |
| Product type | Amino Acid/protein |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Kosher, No Allergies, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for 100% Pure Glycine by NutraBio, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 1 scoop (1000mg) mixed into your favorite beverage between meals 1-3 times daily, or as recommended by your physician.
1 serving -Mixed with 8-16 oz - Favorite Beverage 1-3x daily
General Statements
Powder
Manufactured in a GMP & FDA Inspected Facility
Pharmaceutical Grade. HPLC Lab Tested for Potency.
Serving Scoop Included (May Settle To The Bottom During Shipping.)
FDA Statement of Identity
Dietary Supplement
Quality and purity since 1996. NutraBio manufactures in our own FDA registered & inspected GMP facility complying with FDA 21 CFR Part 111 regulations.
Formulation
Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten Free & BSE/TSE Free. No added sugars, salt, preservatives, salicylates, or artificial color, flavor or fragrance.
Vegetarian -Allergen Free - Non GMO -Gluten Free -BSE/TSE Free
Vegetarian
Allergen Free
No fillers - No excipients -No additives
Free of Harmful Impurities.
Zero Fillers or Excipients Inferior Ingredients Banned Substances - Added Sugars Proprietary Blends Hidden Ingredients
Precautions
Warning: Not intended for the use by persons under the age of 18. Keep out of reach of children.
If you are pregnant, breastfeeding, have known medical conditions (including kidney or liver disease) or are taking prescription or OTC medication(s) consult with your health care practitioner before using this product.
Brand IP Statement(s)
Amino Therapy
NutraBio Since 1996
Formula
Free Form Amino Acid
Kosher, Vegetarian, Hypoallergenic, Non-GMO, Gluten Free & BSE/TSE Free
Seals/Symbols
OU
Storage
Store in cool dry place.
FDA Disclaimer Statement
+These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
23210-006 B20203-002
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
100% Pure Glycine by NutraBio label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in 100% Pure Glycine by NutraBio
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Gram(s) Dosage formPowder Servings per container500 Amounts shown are per serving.
Glycine
Interacts with1 drug
Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...
Glycine monograph & interactionsOther (inactive) ingredients: Absolutely None. These complete the product’s ingredient list but are not active constituents.
100% Pure Glycine by NutraBio Drug Interactions
HelloPharmacist Interaction Report
NutraBio's 100% Pure Glycine has one documented interaction we need to flag.
Glycine may decrease how well clozapine (Clozaril) works for schizophrenia. A small clinical study in people taking clozapine showed their schizophrenia symptoms worsened when glycine was added — though we don't yet understand exactly why this happens.
Read the full breakdown — every affected drug type, severity by severity
If you're taking clozapine, don't add this supplement without talking to your doctor or pharmacist first. We have interaction data for the one active ingredient here, and this is the only medication-type interaction documented in our records.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against 100% Pure Glycine?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in 100% Pure Glycine interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in 100% Pure Glycine interact with drugs. Each result below shows which ingredient is responsible. Glycine
ClozapineClozaril, Versacloz
How Clozapine interacts with 100% Pure Glycine — through 1 ingredient. Tap an ingredient for the detail:
GlycineClozapine (clozaril) Moderate
Interaction Summary
Theoretically, glycine might decrease the effectiveness of clozapine.
Read the full Glycine + Clozapine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in 100% Pure Glycine with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Glycine
Clozapine (Clozaril)
Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.
Brand information
Manufacturer and brand details for 100% Pure Glycine, from the product label.
NutraBio
See all NutraBio products- Name
- NutraBio Labs, Inc.
- Street Address
- 564 Lincoln Blvd.
- City
- Middlesex
- State
- NJ
- ZipCode
- 08846
- Phone Number
- 732-748-8606
- Web Address
- www.nutrabio.com
100% Pure Glycine by NutraBio: Common Questions
Does 100% Pure Glycine by NutraBio interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What exactly is glycine and what does it do in the body?
Can I take this if I'm pregnant or breastfeeding?
What side effects should I watch for?
Does glycine really work for schizophrenia?
Is this supplement just glycine with nothing else in it?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if 100% Pure Glycine is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind 100% Pure Glycine’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
100% Pure Glycine's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Glycine 5 references
- Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
- Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
- Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
- Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
- Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC