No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

5M Trace Minerals Ingredients & Drug Interactions

by True Botanica

Liquid Category: Mineral
No known interaction
The interaction bottom line No known interaction

5M Trace Minerals is a dietary supplement by True Botanica with 5 active ingredients. Its ingredients are commonly taken for acne and oily skin, rosacea, seborrheic dermatitis and dandruff.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of 5M Trace Minerals by True Botanica

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 5 active ingredients.
  • “5M Trace Minerals” is listed as a grouped ingredient — the label gives one combined amount (1 mL) without saying how much of each component you get.

This product contains 5 active ingredients: sulfur, trace minerals, slate, porphyry, and apatite. Of these, sulfur is the one we have safety and effectiveness data for; it's been studied for skin conditions and some respiratory concerns.

The other four components — trace minerals (a general category), slate, porphyry, and apatite — are mineral sources, though we hold limited monograph data on them. The liquid also contains water, citric acid, and potassium sorbate as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Sulfur's overall clinical evidence instead.

Moderate

Some clinical evidence supports Sulfur for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Scabies — rated "Possibly Effective" (Natural Medicines).
  • On file: Dandruff — rated "Possibly Effective" (Natural Medicines).

Sulfur shows possibly effective evidence for scabies and dandruff. For acne, hay fever, chronic obstructive pulmonary disease (COPD), and the common cold, the evidence is insufficient to rate whether it works.

We don't have effectiveness ratings on file for the trace minerals, slate, porphyry, or apatite in this blend.

The evidence, ingredient by ingredient Sulfur

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Topical sulfur is generally well tolerated, though it can cause skin dryness, irritation, and itching. Taken by mouth, sulfur is less studied.

Oral forms have been reported to cause diarrhea and, in rare cases, metabolic acidosis (a shift in blood pH) — one case report involved very high doses over several days, and underlying kidney or blood-sugar problems may have played a role. Because this is a liquid oral supplement containing sulfur, talk with your healthcare provider before starting, especially if you have kidney disease or diabetes.

Pregnancy and lactation data suggest sulfur is possibly safe, but safety data on the other four ingredients isn't on file — discuss this product with your doctor or pharmacist if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Sulfur

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. We hold no interaction data for trace minerals, slate, porphyry, or apatite.

Use the medication checker below with your exact drugs to be sure.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

This mineral blend may interest you if you're looking for trace mineral support, though effectiveness claims for most of its ingredients aren't established in our data. If you have kidney disease, diabetes, or skin sensitivity, or if you're pregnant or breastfeeding, check with your pharmacist or doctor first.

Run your medications through the checker on this page to be certain.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 5M Trace Minerals, straight from the product label.

Brand True Botanica
Net contents 55 mL; 1.86 Fluid Ounce(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336197
Product type Mineral
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 5M Trace Minerals by True Botanica, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
55
IngredientAmount% DV
Sulfur0 NP--
Trace Minerals10 mg--
5M Trace Minerals1 mL--
Slate0 NP--
Porphyry0 NP--
Apatite0 NP--

Other ingredients: Water, Distilled, Citric Acid, Potassium Sorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before using.

Suggested Usage: 20 drops (1 ml, 1/5 tsp) one to three times daily or as suggested by your health care provider.

Formulation

Made with alcohol free, rhythmical proprietary processes. Contains no milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, sesame, soy, wheat, or gluten.

Made with alcohol free, rhythmical proprietary processes.

Precautions

Consult your health care provider before using this product if you are pregnant, lactating or have other medical concerns or compatibility issues.

FDA Statement of Identity

A Dietary Supplement

See for yourself

5M Trace Minerals by True Botanica label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in 5M Trace Minerals by True Botanica

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container55 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Trace Minerals

10 mg per serving

5M Trace Minerals

1 mL per serving
  • Sulfur
  • › Slate
  • › Porphyry
  • › Apatite

Other (inactive) ingredients: Water, Distilled, Citric Acid, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

5M Trace Minerals by True Botanica Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in 5M Trace Minerals. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for 5M Trace Minerals, from the product label.

True Botanica

See all True Botanica products
Name
True Botanica
Pharmacist Counseling Corner

5M Trace Minerals by True Botanica: Common Questions

Does 5M Trace Minerals by True Botanica interact with any medications?
We do not currently list a known interaction for the mapped ingredients in 5M Trace Minerals. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
5M Trace Minerals contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does sulfur in this product cause diarrhea?
Diarrhea has been reported with oral sulfur supplements. It happens because sulfur is converted to sulfide in your gut, which can irritate the intestines. If you develop loose stools after starting this product, stop and talk to your pharmacist.
Is this safe if I'm pregnant or breastfeeding?
Sulfur is rated possibly safe in pregnancy and lactation, but we don't have safety data on file for the trace minerals, slate, porphyry, or apatite in this blend. Talk with your doctor or pharmacist before taking it during pregnancy or while breastfeeding — they can weigh the risks and benefits for you personally.
Can sulfur help with acne?
The evidence for sulfur and acne is insufficient to rate — meaning we don't have enough reliable data to say whether it works. It may be worth discussing with your dermatologist if you're considering it for that use.
What are the inactive ingredients in this liquid?
This product contains water, citric acid, and potassium sorbate as inactive ingredients — fillers and a preservative to keep the liquid stable.
Is this product safe if I have kidney disease?
Oral sulfur can be converted by your body in ways that may stress your kidneys, especially if you already have kidney disease. Check with your doctor or pharmacist before starting — they'll know your kidney function and can advise you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 5M Trace Minerals is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

5M Trace Minerals label
Go deeper

The Full Monographs Behind 5M Trace Minerals’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

5M Trace Minerals's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sulfur 17 references
  1. Blum, J. E. and Coe, F. L. Metabolic acidosis after sulfur ingestion. N Engl J Med 1977;297(16):869-70. PubMed
  2. Roos, T. C., Alam, M., Roos, S., Merk, H. F., and Bickers, D. R. Pharmacotherapy of ectoparasitic infections. Drugs 2001;61(8):1067-88. PubMed
  3. Diaz, M., Cazorla, D., and Acosta, M. [Efficacy, safety and acceptability of precipitated sulphur petrolatum for topical treatment of scabies at the city of Coro, Falcon State, Venezuela]. Rev Invest Clin 2004;56(5):615-22.
  4. Schmiedel, V. and Klein, P. A complex homeopathic preparation for the symptomatic treatment of upper respiratory infections associated with the common cold: An observational study. Explore (NY) 2006;2(2):109-14. PubMed
  5. Weiser, M., Gegenheimer, L. H., and Klein, P. A randomized equivalence trial comparing the efficacy and safety of Luffa comp.-Heel nasal spray with cromolyn sodium spray in the treatment of seasonal allergic rhinitis. Forsch Komplementarmed 1999;6(3):142- PubMed
  6. FDA OTC ingredients list, April 2010. Available at: www.fda.gov/downloads/AboutFDA/CentersOffices/CDER/UCM135691.pdf (accessed 2/7/15).
  7. Leyden, J. J., McGinley, K. J., Mills, O. H., Kyriakopoulos, A. A., and Kligman, A. M. Effects of sulfur and salicylic acid in a shampoo base in the treatment of dandruff: a double-blind study using corneocyte counts and clinical grading. Cutis 1987;39(6)
  8. Trumbore, M. W., Goldstein, J. A., and Gurge, R. M. Treatment of papulopustular rosacea with sodium sulfacetamide 10%/sulfur 5% emollient foam. J Drugs Dermatol 2009;8(3):299-304.
  9. Pelle, M. T., Crawford, G. H., and James, W. D. Rosacea: II. Therapy. J Am Acad Dermatol 2004;51:499-512.
  10. Blom I, Hornmark AM. Topical treatment with sulfur 10 per cent for rosacea. Acta Derm Venereol 1984;64:358-9. DOI
  11. Gupta, A. K. and Nicol, K. The use of sulfur in dermatology. J Drugs Dermatol 2004;3(4):427-31.
  12. Akhavan, A. and Bershad, S. Topical acne drugs: review of clinical properties, systemic exposure, and safety. Am J Clin Dermatol 2003;4(7):473-92.
  13. Wilkinson RD, Adam JE, Murray JJ, Craig GE. Benzoyl peroxide and sulfur: foundation for acne management. Can Med Assoc J 1966;95(1):28-9.
  14. Food and Drug Administration. Classification of benzoyl peroxide as safe and effective and revision of labeling to drug facts format; topical acne drug products for over-the-counter human use; final rule. Federal Register 2010;75(42):9767-77.
  15. Lin, A. N., Reimer, R. J., and Carter, D. M. Sulfur revisited. J Am Acad Dermatol 1988;18(3):553-8.
  16. Goszcz, A., Kostka-Trabka, E., Grodzinska, L., et al. [The effect of treatment with sulphur water from the spring in Wieslaw in Busko-Solec on levels of lipids, the fibrinolytic system and thrombogenic platelet function in patients with arteriosclerosis].
  17. Contoli M, Gnesini G, Forini G, et al. Reducing agents decrease the oxidative burst and improve clinical outcomes in COPD patients: a randomised controlled trial on the effects of sulphurous thermal water inhalation. ScientificWorldJournal. 2013 Dec 23;20 PubMed

See these in context on the Sulfur monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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