No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

7-Keto Ingredients & Drug Interactions

by Nature's Sunshine

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

7-Keto is a dietary supplement by Nature's Sunshine with 1 active ingredient. Its ingredients are commonly taken for weight loss and fat burning, boosting metabolism, supporting muscle mass.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of 7-Keto by Nature's Sunshine

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 7-Keto, a compound related to DHEA. It also includes inactive ingredients (cellulose, a vegetable capsule, chickweed aerial parts, and magnesium stearate) that help hold the capsule together and deliver the dose.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see 7-keto-dhea's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: weight management and metabolic support.
  • We looked for evidence on: Obesity, body composition, fat loss, metabolic rate.
  • The closest evidence on file: 7-keto-dhea is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

The evidence for 7-Keto isn't established yet in the data we hold. Studies have looked at its use for obesity, depression, PTSD, Raynaud syndrome, and aging, but the available data isn't reliable enough to say whether it works for any of these.

If you're considering it for a specific reason, talk with your pharmacist or doctor about what the current research actually shows.

The evidence, ingredient by ingredient 7-keto-dhea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use appears generally well tolerated in small studies, but we don't know much about long-term safety. A few people in trials reported nausea or vertigo, and there's one case report of lower red blood cell counts (hemoglobin and hematocrit) — though its real-world significance isn't clear.

Because 7-Keto is hormone-related, it's best avoided during pregnancy and while breastfeeding unless you've talked with your doctor.

Side effects, ingredient by ingredient 7-keto-dhea

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for 7-Keto. That said, because it's a hormone-related supplement, it's still smart to run your medications through the search tool on this page before you begin.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

7-Keto might appeal to you if you're interested in exploring compounds related to DHEA, but the evidence for its benefits isn't solid yet. If you're pregnant, breastfeeding, or have a blood disorder, talk with your pharmacist before starting.

Check your medications against our tool below, especially if you take anything hormone-related.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 7-Keto, straight from the product label.

Brand Nature's Sunshine
Barcode (UPC) 099904029224
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2021
DSLD ID 255152
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 7-Keto by Nature's Sunshine, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
099904029224
IngredientAmount% DV
7-Keto75 mg--

Other ingredients: Cellulose, Capsule, Chickweed aerial parts, Vegetable Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Bottle made from 100% post consumer recycled material. We are committed to you and our planet. Scan to learn more.

New look! Same great product

Herbal experts since 1972

Formula

7-Keto is a safe, natural metabolite of DHEA that does not convert into the sex steroids testosterone or estrogen. 7-Keto may increase the body's resting metabolic rate which makes it easier to maintain a desired weight. 7-Keto also boosts the production of cytokines, which contribute to support immune function.

Precautions

Caution: Those with hyperthyroidism should consult their health care professional prior to using 7-Keto capsules. Do not use if inner seal is missing or damaged.

Formulation

Weight management Immune system support

Guaranteed pure

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommended Use: Take 1 capsule daily with a meal.

See for yourself

7-Keto by Nature's Sunshine label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in 7-Keto by Nature's Sunshine

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

7-Keto

No known
interactions
75 mg per serving

7-keto-DHEA is a lab-made metabolite of the hormone DHEA that is marketed mainly for weight loss and a faster metabolism. Unlike DHEA, it is not thoug...

7-Keto monograph & interactions

Other (inactive) ingredients: Cellulose, Capsule, Chickweed aerial parts, Vegetable Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

7-Keto by Nature's Sunshine Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in 7-Keto. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for 7-Keto, from the product label.

Nature's Sunshine

See all Nature's Sunshine products
Name
Nature's Sunshine Products, Inc.
City
Spanish Fork
State
UT
ZipCode
84660
Phone Number
1-800-223-8225
Web Address
www.naturessunshine.com
Pharmacist Counseling Corner

7-Keto by Nature's Sunshine: Common Questions

Does 7-Keto by Nature's Sunshine interact with any medications?
We do not currently list a known interaction for the mapped ingredients in 7-Keto. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
7-Keto contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is 7-Keto?
7-Keto is a compound derived from DHEA, a hormone your body makes naturally. It's marketed for things like weight management and mood, but the solid evidence for those uses isn't there yet.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data isn't there, and because it's hormone-related, it's best avoided during pregnancy. While breastfeeding, there's no reliable safety information either, so steer clear unless your doctor says otherwise.
What side effects have been reported?
In trials, a small number of people reported nausea or dizziness. There's also one case report of lower red blood cell counts in someone taking it for a week, though we don't know how common or serious that is.
How long can I safely take this?
Short-term use looks okay in the small studies we have, but long-term safety isn't well established. If you're thinking of taking it regularly, check in with your pharmacist about what we actually know.
Does it really work for weight loss or mood?
The evidence isn't reliable enough to say yes. Studies have looked at it for obesity, depression, and other uses, but the data doesn't support a clear benefit yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 7-Keto is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

7-Keto label
Go deeper

The Full Monographs Behind 7-Keto’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

7-Keto's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

7-keto-dhea 2 references
  1. Davidson M, Marwah A, Sawchuk RJ, et al. Safety and pharmacokinetic study with escalating doses of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy male volunteers. Clin Invest Med 2000;23:300-10..
  2. Zenk JL, Frestedt JL, Kuskowski MA. HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. J Nutr Biochem 2007;18(9):629-34. PubMed

See these in context on the 7-keto-dhea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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