No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

7-Keto DHEA 25 mg Ingredients & Drug Interactions

by Puritan's Pride

Softgel Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

7-Keto DHEA 25 mg is a dietary supplement by Puritan's Pride with 1 active ingredient. Its ingredients are commonly taken for weight loss and fat burning, boosting metabolism, supporting muscle mass.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of 7-Keto DHEA 25 mg by Puritan's Pride

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: 7-Keto DHEA, a compound derived from DHEA (dehydroepiandrosterone), a hormone your body naturally produces. The remaining ingredients are inactive — soybean oil, gelatin, glycerin, soy lecithin, yellow beeswax, and titanium dioxide — they serve as the capsule and carrier.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see 7-keto-dhea's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Weight loss and fat burning, metabolism support.
  • We looked for evidence on: Obesity, Muscle strength, Athletic performance, Aging, Body composition, Metabolic rate — and 1 related terms.
  • The closest evidence on file: 7-keto-dhea is rated "Insufficient Reliable Evidence To Rate" for Aging skin (Natural Medicines).
  • Also on file: 7-keto-dhea is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Muscle strength, Obesity, Aging.

The evidence for 7-Keto DHEA is not established in the data we hold. Studies have looked at it for post-traumatic stress disorder (PTSD), obesity, depression, Raynaud syndrome (a condition affecting blood flow to your fingers and toes), and aging, but the data we have rates all of these as insufficient to determine whether it actually works.

If you're considering it for one of these reasons, talk with your doctor about what the current research suggests.

The evidence, ingredient by ingredient 7-keto-dhea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use appears generally well tolerated in small studies, but long-term safety hasn't been well studied, so we don't know what happens with extended use. In clinical trials, a small number of people reported nausea and one reported vertigo.

One case describes a man who developed decreased hemoglobin and hematocrit levels (lower red blood cell counts) after taking 25 mg twice daily for a week — though the clinical importance of this isn't clear. 7-Keto DHEA is not recommended during pregnancy or while breastfeeding; the safety data is not sufficient to know either way, and hormone-related supplements are best avoided in these situations.

Side effects, ingredient by ingredient 7-keto-dhea

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for 7-Keto DHEA in our data. That said, because it's a hormone-related supplement, mention it to your pharmacist if you take any hormone-related medications — they can give you personalized advice even if a formal interaction isn't on record.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

7-Keto DHEA is most appropriate for adults looking to explore its potential for PTSD, weight, mood, or aging-related concerns — though the evidence for these uses isn't established yet. If you're pregnant, breastfeeding, or taking any medications that involve hormones or blood cell production, talk with your pharmacist first.

Long-term safety is unclear, so this isn't meant to be taken indefinitely without check-ins.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 7-Keto DHEA 25 mg, straight from the product label.

Brand Puritan's Pride
Barcode (UPC) 025077603695
Net contents 60 Easy to Swallow Rapid Release Softgel(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 286447
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 7-Keto DHEA 25 mg by Puritan's Pride, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
025077603695
IngredientAmount% DV
7-Keto DHEA25 mg--

Other ingredients: Soybean Oil, Gelatin, Glycerin, Soy Lecithin, yellow Beeswax, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: Not for use by individuals under the age of 18.

Do not use if pregnant or nursing.

Consult a physician or licensed qualified health care professional before using this product if you have, or have a family history of prostate cancer, prostate enlargement, heart disease, low "good" cholesterol (HDL), or if you are using any other dietary supplement, prescription drug, or over-the-counter drug or have any other medical condition.

Do not use if seal under cap is broken or missing.

Do not exceed recommended dose.

Contains soy ingredients. Contains bioengineered food ingredients.

Keep out of reach of children.

To report any adverse events call 1-800-332-1088.

Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects. Possible side effects include acne, hair loss, hair growth on the face (in women), aggressiveness, irritability and increased levels of estrogen. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heartbeat, dizziness, blurred vision, or other similar symptoms.

Storage

Store at room temperature.

General Statements

To reorder item # 60369 www.puritan.com 1-800-645-1030

Brand IP Statement(s)

Copyright 2021 Puritan's Pride, Inc.

7-Keto is a registered trademark of Lonza Consumer Health Inc.

Seals/Symbols

QA Quality Assured

Formulation

Naturally occurring metabolite

No artificial flavor or sweetener, no sugar, no starch, no milk, no lactose, no gluten, no wheat, no yeast, no fish. Sodium free.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take one (1) softgel up to four times daily, preferably with a meal.

See for yourself

7-Keto DHEA 25 mg by Puritan's Pride label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in 7-Keto DHEA 25 mg by Puritan's Pride

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

7-Keto DHEA

No known
interactions
25 mg per serving Form: 7-Keto Dehydroepiandrosterone Acetate

7-keto-DHEA is a lab-made metabolite of the hormone DHEA that is marketed mainly for weight loss and a faster metabolism. Unlike DHEA, it is not thoug...

7-Keto DHEA monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Soy Lecithin, Yellow Beeswax, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

7-Keto DHEA 25 mg by Puritan's Pride Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in 7-Keto DHEA 25 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for 7-Keto DHEA 25 mg, from the product label.

Puritan's Pride

See all Puritan's Pride products
Name
Puritan's Pride, Inc.
City
Ronkonkoma
State
NY
ZipCode
11779
Phone Number
1-800-645-1030
Web Address
www.puritan.com
Pharmacist Counseling Corner

7-Keto DHEA 25 mg by Puritan's Pride: Common Questions

Does 7-Keto DHEA 25 mg by Puritan's Pride interact with any medications?
We do not currently list a known interaction for the mapped ingredients in 7-Keto DHEA 25 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
7-Keto DHEA 25 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this affect my blood work or blood cells?
One case report described decreased hemoglobin and hematocrit (red blood cell measures) in someone taking 7-Keto DHEA 25 mg twice daily for a week, though the clinical significance isn't clear. If you're having blood work done or have a history of blood cell issues, mention this supplement to your doctor.
Can I take this while pregnant or breastfeeding?
No. The safety data isn't sufficient to know either way, and because it's a hormone-related supplement, it's best avoided during pregnancy and breastfeeding. Talk with your doctor about your options.
What side effects should I watch for?
In clinical trials, a small number of people reported nausea, and one reported vertigo (dizziness). The most serious concern from case reports is a potential effect on red blood cell counts, though this is rare and the significance isn't well understood. Stop and contact your doctor if you notice unusual tiredness, dizziness, or nausea.
How long can I safely take this?
Short-term use appears well tolerated in small studies, but long-term safety hasn't been established. We don't have good data on what happens if you take it for months or years. Check in with your pharmacist or doctor about how long is appropriate for your situation.
Does 7-Keto DHEA actually work for weight loss or aging?
The evidence isn't established in the data we hold. Studies have looked at it for obesity and aging, but we can't say from the research available whether it actually works. Your doctor can discuss what the current research suggests.
Does this contain soy?
Yes — the inactive ingredients include soybean oil and soy lecithin. If you have a soy allergy, this isn't the product for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 7-Keto DHEA 25 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

7-Keto DHEA 25 mg label
Go deeper

The Full Monographs Behind 7-Keto DHEA 25 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

7-Keto DHEA 25 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

7-keto-dhea 2 references
  1. Davidson M, Marwah A, Sawchuk RJ, et al. Safety and pharmacokinetic study with escalating doses of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy male volunteers. Clin Invest Med 2000;23:300-10..
  2. Zenk JL, Frestedt JL, Kuskowski MA. HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. J Nutr Biochem 2007;18(9):629-34. PubMed

See these in context on the 7-keto-dhea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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