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Dietary supplement

7-KetoTrim Ingredients & Drug Interactions

by Country Life

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

7-KetoTrim is a dietary supplement by Country Life with 3 active ingredients. Its ingredients are commonly taken for memory and cognitive support, nerve pain (neuropathy), energy and fatigue.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Acetyl L-Carnitine, L-Tyrosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of 7-KetoTrim by Country Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (20 mg) without saying how much of each component you get.

7-KetoTrim contains 3 active ingredients. Acetyl L-Carnitine supports nerve and cognitive function.

L-Tyrosine is an amino acid that helps your body make neurotransmitters and thyroid hormones. 7-Keto is a compound derived from DHEA.

The capsules also contain inactive ingredients—cellulose, magnesium stearate, and silica—that help form and stabilize the product.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Weight loss and fat burning with exercise.
  • We looked for evidence on: Obesity, Dyslipidemia, Aging, Metabolic support, Body composition, Metabolism.
  • The closest evidence on file: Acetyl-l-carnitine is rated "Insufficient Reliable Evidence To Rate" for Aging skin (Natural Medicines).
  • Also on file: Acetyl-l-carnitine is rated "Insufficient Reliable Evidence To Rate" for Dyslipidemia, Obesity.
  • Also on file: 7-keto-dhea is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Obesity.

The evidence varies by ingredient and use. Acetyl L-Carnitine is rated possibly effective for age-related cognitive decline, Alzheimer disease, diabetic nerve pain, and depression.

L-Tyrosine is considered effective for phenylketonuria (PKU), possibly effective for cognitive function and memory, but possibly ineffective for athletic performance. 7-Keto has insufficient evidence for all conditions we hold data on—including obesity, depression, and aging—meaning the evidence isn't established in what we have on file.

If you're considering this for a specific reason, talk with your pharmacist about what the research actually shows for your situation.

The evidence, ingredient by ingredient Acetyl-l-carnitine Tyrosine 7-keto-dhea

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Acetyl L-Carnitine is generally well tolerated short-term, but long-term safety isn't fully established. Common side effects include agitation, dry mouth, headache, insomnia, and reduced appetite; a metabolite can cause a fishy odor in urine, breath, and sweat.

Some people experience nausea, vomiting, diarrhea, or stomach upset, though these don't usually occur more often than with placebo. L-Tyrosine is generally well tolerated in healthy adults and causes fatigue, headache, heartburn, or nausea at typical doses, but safety data is limited.

7-Keto appears tolerated in short-term studies but long-term safety is not well established; nausea and vertigo have been reported occasionally. Data on pregnancy safety is either absent or advises against use; for breastfeeding, safety is unknown or not recommended.

Talk with your doctor or pharmacist before using if you're pregnant or nursing.

Side effects, ingredient by ingredient Acetyl-l-carnitine Tyrosine 7-keto-dhea

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Acetyl-l-carnitine, Tyrosine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; Parkinson's medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product if you take serotonergic drugs (Moderate risk of serotonin syndrome), blood thinners like warfarin or acenocoumarol (Moderate risk of increased bleeding), levodopa for Parkinson's disease (Moderate risk of reduced effectiveness), or thyroid hormone replacement (Moderate risk of reduced effectiveness or added effects).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

7-KetoTrim may be of interest to someone looking to support cognition or nerve function, since Acetyl L-Carnitine has some evidence behind it for those areas. However, if you take any blood thinners, medications for Parkinson's disease, thyroid hormone replacement, or serotonergic drugs (including many antidepressants), you'll need to check this product with your pharmacist first.

Long-term safety data is limited, so talk with us before starting if you plan to use it regularly or have any health conditions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 1, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 7-KetoTrim, straight from the product label.

Brand Country Life
Barcode (UPC) 015794030911
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Oct 1, 2012
DSLD ID 13737
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 7-KetoTrim by Country Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
015794030911
IngredientAmount% DV
Proprietary Blend20 mg--
Acetyl L-Carnitine0 NP--
L-Tyrosine0 NP--
7-Keto100 mg--

Other ingredients: Cellulose, Magnesium Stearate, Silica, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Seals/Symbols

K PARVE

PLEASE RECYCLE (recycle)

Certified Vegan AVA American Vegetarian Association(TM)

Certified GF Gluten-Free(R)

Good Manufacturing Practices GMP CERTIFIED

Our manufacturing supports wind power. renewablechoice.com

Suggested/Recommended/Usage/Directions

Directions: Adults take one (1) capsule twice daily with meals for optimal effect. Use with a low-fat, reduced calorie diet and daily exercise program. As a reminder, discuss your diet and exercise plan and the supplements and medications that you take with your health care providers.

Precautions

WARNING: Not for use by anyone under the age of 18.

Do not use this product if you are pregnant or nursing. If you are under medical care, taking medication or planning a surgery, consult your doctor before using this product.

Do not accept if seal is broken.

Keep out of the reach of children.

If any adverse reactions occur, stop taking the product and consult your doctor.

Storage

Store between 59(0)-86(0)F.

Formulation

NO: Yeast, corn, wheat, soy, gluten, milk, salt, sugar, preservatives or artificial color.

Brand IP Statement(s)

7-Keto(R) is a registered trademark of Humanetics Corporation

General

Product No. 3091 09C10L

See for yourself

7-KetoTrim by Country Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in 7-KetoTrim by Country Life

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

20 mg per serving

7-Keto

No known
interactions
100 mg per serving

7-keto-DHEA is a lab-made metabolite of the hormone DHEA that is marketed mainly for weight loss and a faster metabolism. Unlike DHEA, it is not thoug...

7-Keto monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate, Silica, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

7-KetoTrim by Country Life Drug Interactions

Want to check YOUR meds against 7-KetoTrim?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in 7-KetoTrim with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Acetyl L-Carnitine4 drug types · 203 drugs

Acenocoumarol (Sintrom)

Theoretically, acetyl-L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine, the parent compound of acetyl-L-carnitine, might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant that is similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation when L-carnitine was taken with acenocoumarol. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product. It is unclear if such an interaction would also occur with acetyl-L-carnitine.

Likelihood Possible Evidence D
Serotonergic Drugs

Theoretically, acetyl-L-carnitine might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders, when taken with serotonergic drugs.
Animal research shows that acetyl-L-carnitine can increase levels of serotonin in the brain.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, acetyl-L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism. It is unclear if such an interaction would occur with acetyl-L-carnitine.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, acetyl-L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine, the parent compound of acetyl-L-carnitine, might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with acetyl-L-carnitine and warfarin.

Likelihood Possible Evidence D

L-Tyrosine2 drug types · 21 drugs

Levodopa

Theoretically, tyrosine might decrease the effectiveness of levodopa.
Tyrosine and levodopa compete for absorption in the proximal duodenum by the large neutral amino acid (LNAA) transport system. Advise patients to separate doses of tyrosine and levodopa by at least 2 hours.

Likelihood Probable Evidence D
Thyroid Hormone

Theoretically, tyrosine might have additive effects with thyroid hormone medications.
Tyrosine is a precursor to thyroxine and might increase levels of thyroid hormones.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for 7-KetoTrim, from the product label.

Country Life

See all Country Life products
Name
Country Life
Street Address
101 Corporate Drive
City
Hauppauge
State
NY
ZipCode
11788
Web Address
www.countrylifevitamins.com
Pharmacist Counseling Corner

7-KetoTrim by Country Life: Common Questions

Does 7-KetoTrim by Country Life interact with any medications?
Yes. Based on its ingredients, 7-KetoTrim has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
7-KetoTrim contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does 7-KetoTrim work?
That depends on what you're using it for. Acetyl L-Carnitine is possibly effective for cognitive decline, Alzheimer disease, nerve pain from diabetes, and depression. L-Tyrosine works for PKU and is possibly effective for memory and cognition. 7-Keto has insufficient evidence on file for any of the conditions we track. Your pharmacist can give you a clearer picture for your specific goal.
What are the most common side effects?
From Acetyl L-Carnitine: agitation, dry mouth, headache, insomnia, and reduced appetite. From L-Tyrosine: fatigue, headache, heartburn, and nausea. Some people also report stomach upset or a fishy odor in urine and breath (from Acetyl L-Carnitine). Most people tolerate it, but if side effects bother you, mention it to your pharmacist.
Is it safe during pregnancy?
The safety data advises against use during pregnancy for all three ingredients. If you're pregnant or planning to become pregnant, talk with your doctor before taking this product.
Is it safe while breastfeeding?
Safety while breastfeeding is unknown for Acetyl L-Carnitine and 7-Keto, and not recommended for L-Tyrosine. Talk with your doctor or pharmacist if you're breastfeeding and considering this product.
Why are there warnings about blood thinners and thyroid medication?
Acetyl L-Carnitine may increase how well blood thinners work, raising your bleeding risk. L-Tyrosine is a precursor to thyroid hormone and might add to the effects of thyroid medication. Both are moderate-level concerns, so your pharmacist or doctor needs to know if you take either type of drug.
What's the difference between this and other energy or cognition supplements?
We only have data on this product's three ingredients. The evidence for each is different—Acetyl L-Carnitine has the strongest support, L-Tyrosine has mixed evidence depending on the use, and 7-Keto doesn't have established evidence in our files. Your pharmacist can compare it with other options if you'd like.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if 7-KetoTrim is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

7-KetoTrim label
Sources

Sources & How We Checked

7-KetoTrim's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Acetyl-l-carnitine 22 references
  1. Thal LJ, Carta A, Clarke WR, et al. A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's Disease. Neurology 1996;47:705-11. PubMed
  2. Sano M, Bell K, Cote L, et al. Double-blind parallel design pilot study of acetyl levocarnitine in patients with Alzheimer's Disease. Arch Neurol 1992;49:1137-41. PubMed
  3. Spagnoli A, Lucca U, Menasce G, et al. Long-term acetyl-L-carnitine treatment in Alzheimer's Disease. Neurology 1991;41:1726-32. PubMed
  4. Brooks JO 3rd, Yesavage JA, Carta A, Bravi D. Acetyl L-carnitine slows decline in younger patients with Alzheimer's disease: a reanalysis of a double-blind, placebo-controlled study using the trilinear approach. Int Psychoger 1998;10:193-203. PubMed
  5. Pettegrew JW, Klunk WE, Panchalingam K, et al. Clinical and neurochemical effects of acetyl-L-carnitine in Alzheimer's disease. Neurobiol Aging 1995;16:1-4. PubMed
  6. Rai G, Wright G, Scott L, et al. Double-blind, placebo controlled study of acetyl-l-carnitine in patients with Alzheimer's dementia. Curr Med Res Opin 1990;11:638-47. PubMed
  7. Benvenga S, Ruggeri RM, Russo A, et al. Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. J Clin Endocrinol Meta
  8. Montgomery SA, Thal LJ, Amrein R. Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease. Int Clin Psychopharmacol 2003;18:61-71.. PubMed
  9. Martinez E, Domingo P, Roca-Cusachs A. Potentiation of acenocoumarol action by L-carnitine. J Intern Med 1993;233:94.
  10. Hudson S, Tabet N. Acetyl-L-carnitine for dementia. Cochrane Database Syst Rev 2003;2:CD003158.. PubMed
  11. Bachmann HU, Hoffmann A. Interaction of food supplement L-carnitine with oral anticoagulant acenocoumarol. Swiss Med Wkly 2004;134:385. PubMed
  12. De Grandis D, Minardi C. Acetyl-L-carnitine (levacecarnine) in the treatment of diabetic neuropathy. A long-term, randomised, double-blind, placebo-controlled study. Drugs R D 2002;3:223-31. PubMed
  13. 12761 Benvenga S, Amato A, Calvani M, Trimarchi F. Effects of carnitine on thyroid hormone action. Ann N Y Acad Sci 2004;1033:158-67. PubMed
  14. Sima AAF, Calvani M, Mehra M, et al. Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: An analysis of two randomized, placebo-controlled trials. Diabetes Care 2005;28:89-94.
  15. Youle, M. and Osio, M. A double-blind, parallel-group, placebo-controlled, multicentre study of acetyl L-carnitine in the symptomatic treatment of antiretroviral toxic neuropathy in patients with HIV-1 infection. HIV.Med. 2007;8(4):241-250.
  16. Brennan BP, Jensen JE, Hudson JI, Coit CE, Beaulieu A, Pope HG Jr, Renshaw PF, Cohen BM. A placebo-controlled trial of acetyl-L-carnitine and a-lipoic acid in the treatment of bipolar depression. J Clin Psychopharmacol. 2013 Oct;33(5):627-35.
  17. Ledinek AH, Sajko MC, Rot U. Evaluating the effects of amantadin, modafinil and acetyl-L-carnitine on fatigue in multiple sclerosis--result of a pilot randomized, blind study. Clin Neurol Neurosurg. 2013 Dec;115 Suppl 1:S86-9. PubMed
  18. Martinotti G, Andreoli S, Reina D, Di Nicola M, Ortolani I, Tedeschi D, Fanella F, Pozzi G, Iannoni E, D'Iddio S, Prof LJ. Acetyl-l-Carnitine in the treatment of anhedonia, melancholic and negative symptoms in alcohol dependent subjects. Prog Neuropsychop PubMed
  19. Baek SM, Zheng R, Seo EJ, Hwang DY, Kim BH. Pharmacokinetic comparisons of two acetyl-L-carnitine formulations in healthy Korean volunteers. Int J Clin Pharmacol Ther. 2015;53(11):980-6. PubMed
  20. Goodison G, Overeem K, de Monte V, Siskind D. Mania associated with self-prescribed acetyl-l-carnitine in a man with bipolar I disorder. Australas Psychiatry. 2017;25(1):13-4.
  21. Bruno A, Pandolfo G, Crucitti M, Lorusso S, Zoccali RA, Muscatello MR. Acetyl-L-Carnitine Augmentation of Clozapine in Partial-Responder Schizophrenia: A 12-Week, Open-Label Uncontrolled Preliminary Study. Clin Neuropharmacol. 2016;39(6):277-80. PubMed
  22. Veronese N, Stubbs B, Solmi M, Ajnakina O, Carvalho AF, Maggi S. Acetyl-L-Carnitine Supplementation and the Treatment of Depressive Symptoms: A Systematic Review and Meta-Analysis. Psychosom Med. 2018;80(2):154-9. PubMed

See these in context on the Acetyl-l-carnitine monograph →

Tyrosine 4 references
  1. Meyer JS, Welch KM, Deshmukh VD, et al. Neurotransmitter precursor amino acids in the treatment of multi-infarct dementia and Alzheimer's disease. J Amer Geriat Soc 1977;25:289-98.
  2. DiPiro JT, Talbert RL, Yee GC, et al; eds. Pharmacotherapy: A pathophysiologic approach. 4th ed. Stamford, CT: Appleton & Lange, 1999.
  3. Wood DR, Reimherr FW, Wender PH. Amino acid precursors for the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 1985;21:146-9.
  4. van Spronsen FJ, van Rijn M, Bekhof J. Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets. Am J Clin Nutr 2001;73:153-7. PubMed

See these in context on the Tyrosine monograph →

7-keto-dhea 2 references
  1. Davidson M, Marwah A, Sawchuk RJ, et al. Safety and pharmacokinetic study with escalating doses of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy male volunteers. Clin Invest Med 2000;23:300-10..
  2. Zenk JL, Frestedt JL, Kuskowski MA. HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults. J Nutr Biochem 2007;18(9):629-34. PubMed

See these in context on the 7-keto-dhea monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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