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Dietary supplement

Activated Coconut Shell Charcoal Powder 500 mg Ingredients & Drug Interactions

by Solaray

Powder Category: Non-nutrient/non-botanical
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Activated Coconut Shell Charcoal Powder 500 mg is a dietary supplement by Solaray with 1 active ingredient. Its ingredients are commonly taken for poisoning and drug overdose (in emergency care), gas and bloating, upset stomach.Based on those ingredients, 2,027 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Activated Charcoal. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Activated Coconut Shell Charcoal Powder 500 mg by Solaray

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient, activated charcoal, derived from coconut shell and supplied as a 500 mg powder. Activated charcoal works by adsorbing, or binding to, certain substances in the digestive tract, and that binding is the basis of its documented interactions with other medications.

The product's listed inactive ingredients are not available in our data, so we cannot tell you what else is in it beyond the active ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Cleansing.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The best-supported use in our data is poisoning, which is rated Possibly Effective. For hyperphosphatemia (high phosphate in the blood), wound healing, dyspepsia (indigestion), hangover, and hypercholesterolemia (high cholesterol), our data rates the evidence as Insufficient Reliable Evidence To Rate, so we cannot say whether it helps for those uses.

The evidence, ingredient by ingredient Activated Charcoal

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, activated charcoal is generally well tolerated. The most common side effects are gastrointestinal: constipation, which is usually temporary, along with black stools, abdominal pain, bloating, and gas.

Rarely, it may cause a bowel obstruction, and serious effects such as pulmonary aspiration (breathing material into the lungs) have been reported. For pregnancy and breastfeeding, our data rates safety as Possibly Safe, and the safety notes say it is not well studied for routine use in pregnancy.

Our data also notes that there is little safety data overall. Please talk with your own doctor or pharmacist before using it, especially if you are pregnant or breastfeeding.

Side effects, ingredient by ingredient Activated Charcoal

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Activated Charcoal.
  • The most serious interaction on file is rated Major.
  • For scale: 2,028 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check oral medications first, since activated charcoal is rated Major for reducing their absorption and effect. Oral contraceptives and alcohol are rated Moderate.

Confirm your exact medications with your own doctor or pharmacist, and use the search tool on this page to look up specific names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product may be of interest to adults looking for a charcoal supplement for a use where our data shows some support, such as poisoning under medical guidance. People who take oral medications, use oral contraceptives, or drink alcohol regularly should be especially careful.

Please review the product with your own doctor or pharmacist before you start, particularly if you have any ongoing prescriptions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Activated Coconut Shell Charcoal Powder 500 mg, straight from the product label.

Brand Solaray
Barcode (UPC) 076280426083
Net contents 5.3 Ounce(s); 150 Gram(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 325903
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Activated Coconut Shell Charcoal Powder 500 mg by Solaray, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
300
UPC/BARCODE
076280426083
IngredientAmount% DV
Activated Charcoal500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Solaray Est. 1973 A Brighter Way 1973

Formulation

Cleansing

Vegan

Non GMO Project Verified nongmoproject.org

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Lab Verified Vegan Non GMO Project Verified nongmoproject.org

General Statements

Since 1973, we've scoured the globe for the highest quality ingredients, connecting you with the most efficacious supplements that help you live brighter & embrace the moments that matter most.

Precautions

Warning: Do not use if safety seal is broken of missing.

Keep out of reach of children.

Keep your licensed health care practitioner informed when using this product. A darkening of the stool may result from this product.

This product is highly absorbent and may reduce the effectiveness of some medications or nutritional supplements.

California Residents Only Warning: Reproductive Harm - www.P65Warnings.ca.gov

Suggested/Recommended/Usage/Directions

Directions: Use only as directed. Take 500 mg (approximately 1/4 rounded teaspoon) with a glass of water. Take between meals.

Storage

Store in a cool, dry place.

Packaged by weight, not volume. Some settling of contents may occur.

Formula

Discussion: Activated Charcoal is a fine powder that dates back to 400 BCE., where it was used to purify water. Charcoal may support total body cleansing due to its highly adsorptive properties.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Activated Coconut Shell Charcoal Powder 500 mg by Solaray label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Activated Coconut Shell Charcoal Powder 500 mg by Solaray

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container300 Amounts shown are per serving.

Activated Charcoal

Interacts with
2,027 drugs
500 mg per serving Form: Coconut

Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings...

Activated Charcoal monograph & interactions
Interaction report

Activated Coconut Shell Charcoal Powder 500 mg by Solaray Drug Interactions

Want to check YOUR meds against Activated Coconut Shell Charcoal Powder 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,027Drugs
2,022 Major 5 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Activated Coconut Shell Charcoal Powder 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Activated Charcoal3 drug types · 2,027 drugs

Oral Drugs

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Activated charcoal adsorbs various drugs and may reduce their absorption and/or half-life. Examples of affected drugs include acetaminophen, aminophylline, amiodarone, atenolol, carbamazepine, dapsone, digoxin, disopyramide, fluoxetine, indomethacin, moxifloxacin, nadolol, phenytoin, phenobarbital, piroxicam, quinine, sotalol, theophylline, tricyclic antidepressants, valproate, and verapamil. Avoid co-administration, except after drug overdose.

Likelihood Probable Evidence B
Alcohol (Ethanol)

The binding action of activated charcoal may be reduced by alcohol.
Alcohol may lower the adsorptive capacity of activated charcoal.

Likelihood Probable Evidence D
Contraceptive Drugs

Activated charcoal may reduce the clinical effects of oral contraceptives.
Activated charcoal, taken in a dose of 5 grams four times daily for 3 days, may bind to, and reduce the absorption of, oral contraceptives, thereby limiting their effectiveness and increasing the risk of contraceptive failure. However, some clinical research shows that the risk for this interaction is minimal when activated charcoal is taken either 3 hours after or at least 12 hours before oral contraceptives.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Activated Coconut Shell Charcoal Powder 500 mg, from the product label.

Solaray

See all Solaray products
Name
Nutraceutical Corp.
Web Address
www.nutraceutical.com
Pharmacist Counseling Corner

Activated Coconut Shell Charcoal Powder 500 mg by Solaray: Common Questions

Does Activated Coconut Shell Charcoal Powder 500 mg by Solaray interact with any medications?
Yes. Based on its ingredients, Activated Coconut Shell Charcoal Powder 500 mg has a known interaction with 2,027 medications, including 2022 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Activated Coconut Shell Charcoal Powder 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take this during pregnancy?
Our data rates pregnancy and breastfeeding safety as Possibly Safe, and the safety notes say it is not well studied for routine use in pregnancy. Please talk with your own doctor or pharmacist for advice about your situation.
What side effects can activated charcoal cause?
The most common side effects are constipation, black stools, abdominal pain, bloating, and gas, and these are generally well tolerated. Rarely, it may cause a bowel obstruction.
Does activated charcoal work for poisoning?
Poisoning is the use rated Possibly Effective in our data. It is not a substitute for emergency care, so contact your local emergency services or poison control if you think someone has been poisoned.
What is activated charcoal used for?
Our data lists uses including poisoning, hyperphosphatemia, wound healing, dyspepsia, hangover, and hypercholesterolemia. Only poisoning is rated Possibly Effective, and the other uses are rated Insufficient Reliable Evidence To Rate.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Activated Coconut Shell Charcoal Powder 500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Activated Coconut Shell Charcoal Powder 500 mg label
Go deeper

The Full Monographs Behind Activated Coconut Shell Charcoal Powder 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Activated Coconut Shell Charcoal Powder 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Activated Charcoal 14 references
  1. Kaaja RJ, Kontula KK, Raiha A, Laatikainen T. Treatment of cholestasis of pregnancy with peroral activated charcoal. A preliminary study. Scand J Gastroenterol 1994;29:178-81.
  2. Anon. Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin T
  3. Park GD, Spector R, Kitt TM. Superactivated charcoal versus cholestyramine for cholesterol lowering: a randomized cross-over trial. J Clin Pharmacol 1988;28:416-9. PubMed
  4. Hoegberg LC, Angelo HR, Christophersen AB, Christensen HR. Effect of ethanol and pH on the adsorption of acetaminophen (paracetamol) to high surface activated charcoal, in vitro studies. J Toxicol Clin Toxicol 2002;40:59-67. PubMed
  5. Brahmi N, Kouraichi N, Thabet H, Amamou M. Influence of activated charcoal on the pharmacokinetics and the clinical features of carbamazepine poisoning. Am J Emerg Med 2006;24(4):440-3. PubMed
  6. Gude AB, Hoegberg LC, Angelo HR, Christensen HR. Dose-dependent adsorptive capacity of activated charcoal for gastrointestinal decontamination of a simulated paracetamol overdose in human volunteers. Basic Clin Pharmacol Toxicol 2010;106(5)406-10. PubMed
  7. Wananukul W, Klaikleun S, Sriapha C, Tongpoo A. Effect of activated charcoal in reducing paracetamol absorption at supra-therapeutic dose. J Med Assoc Thai 2010;93(10):1145-9.
  8. Wang Z, Cui M, Tang L, et al. Oral activated charcoal suppresses hyperphosphataemia in haemodialysis patients. Nephrology (Carlton) 2012;17(7):616-20. PubMed
  9. Wang X, Mondal S, Wang J, et al. Effect of activated charcoal on apixaban pharmacokinetics in healthy subjects. Am J Cardiovasc Drugs 2014;14(2):147-54. PubMed
  10. Chyka PA, Seger D, Krenzelok EP, et al. Position paper: single-dose activated charcoal. Clin Toxicol (Phila) 2005;43(2):61-87. PubMed
  11. Chiew AL, Gluud C, Brok J, Buckley NA. Interventions for paracetamol (acetaminophen) overdose. Cochrane Database Syst Rev 2018;2:CD003328. PubMed
  12. Elomaa K, Ranta S, Tuominen J, Lähteenmäki P. Charcoal treatment and risk of escape ovulation in oral contraceptive users. Hum Reprod. 2001;16(1):76-81. PubMed
  13. Gao Y, Wang G, Li Y, Lv C, Wang Z. Effects of oral activated charcoal on hyperphosphatemia and vascular calcification in Chinese patients with stage 3-4 chronic kidney disease. J Nephrol. 2019;32(2):265-72. PubMed
  14. Skov K, Graudal NA, Jürgens G. The effect of activated charcoal on drug exposure following intravenous administration: A meta-analysis. Basic Clin Pharmacol Toxicol 2021;128(4):568-578. PubMed

See these in context on the Activated Charcoal monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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