Atorvastatin

Generic name: Pronounced as (a tore' va sta tin)
Brand names
  • Lipitor®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 08/15/2015

[Posted 07/20/2021]

AUDIENCE: Patient, Health Professional, OBGYN, Cardiology, Endocrinology, Pharmacy

ISSUE: The FDA is requesting revisions to the information about use in pregnancy in the prescribing information of the entire class of statin medicines. These changes include removing the contraindication against using these medicines in all pregnant patients. A contraindication is FDA's strongest warning and is only added when a medicine should not be used because the risk clearly outweighs any possible benefit. Because the benefits of statins may include prevention of serious or potentially fatal events in a small group of very high-risk pregnant patients, contraindicating these drugs in all pregnant women is not appropriate.

FDA expects removing the contraindication will enable health care professionals and patients to make individual decisions about benefit and risk, especially for those at very high risk of heart attack or stroke. This includes patients with homozygous familial hypercholesterolemia and those who have previously had a heart attack or stroke.

BACKGROUND: Statins are a class of prescription medicines that have been used for decades to lower low-density lipoprotein (LDL-C or "bad") cholesterol in the blood. Medicines in the statin class include atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, and simvastatin.

RECOMMENDATIONS:

  • Patients: Patients taking statins should notify their health care professionals if they become pregnant or suspect they are pregnant. Your health care professional will be able to advise whether you should stop taking the medicine during pregnancy and whether you may stop your statin temporarily while breastfeeding. Patients who are at high risk of heart attack or stroke who require statins after giving birth should not breastfeed and should use alternatives such as infant formula.

  • Health Care Professionals: Health care professionals should discontinue statin therapy in most pregnant patients, or they can consider the ongoing therapeutic needs of the individual patient, particularly those at very high risk for cardiovascular events during pregnancy. Because of the chronic nature of cardiovascular disease, treatment of hyperlipidemia is not generally necessary during pregnancy. Discuss with patients whether they may discontinue statins temporarily while breastfeeding. Advise those who require a statin because of their cardiovascular risk that breastfeeding is not recommended because the medicine may pass into breast milk

The FDA hopes the revised language in the prescribing information will help reassure health care professionals that statins are safe to prescribe in patients who can become pregnant, and help them reassure patients with unintended statin exposure in early pregnancy or before pregnancy is recognized that the medicine is unlikely to harm the unborn baby.

For more information visit the FDA website at: http://www.fda.gov/Safety/MedWatch/SafetyInformation and http://www.fda.gov/Drugs/DrugSafety.

Atorvastatin is used together with diet, weight loss, and exercise to reduce the risk of heart attack and stroke and to decrease the chance that heart surgery will be needed in people who have heart disease or who are at risk of developing heart disease. Atorvastatin is also used to decrease the amount of fatty substances such as low-density lipoprotein (LDL) cholesterol ('bad cholesterol') and triglycerides in the blood and to increase the amount of high-density lipoprotein (HDL) cholesterol ('good cholesterol') in the blood. Atorvastatin may also be used to decrease the amount of cholesterol and other fatty substances in the blood in children and teenagers 10 to 17 years of age who have familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally). Atorvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.

Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats with atorvastatin has been shown to prevent heart disease, angina (chest pain), strokes, and heart attacks.

Atorvastatin comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take atorvastatin at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take atorvastatin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may start you on a low dose of atorvastatin and gradually increase your dose, not more than once every 2 to 4 weeks.

Continue to take atorvastatin even if you feel well. Do not stop taking atorvastatin without talking to your doctor.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking atorvastatin,

  • tell your doctor and pharmacist if you are allergic to atorvastatin, any other medications, or any of the ingredients in atorvastatin tablets. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antifungal medications such as itraconazole (Sporanox) and ketoconazole (Nizoral); boceprevir (Victrelis); cimetidine (Tagamet); clarithromycin (Biaxin); cobicistat-containing medications (Stribild); colchicine (Colcrys); digoxin (Lanoxin); efavirenz (Sustiva, in Atripla); oral contraceptives (birth control pills); other cholesterol-lowering medications such as fenofibrate (Tricor), gemfibrozil (Lopid), and niacin (nicotinic acid, Niacor, Niaspan); certain HIV protease inhibitors such as darunavir (Prezista), fosamprenavir (Lexiva), lopinavir (in Kaletra), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), saquinavir (Invirase), and tipranavir (Aptivus); medications that suppress the immune system such as cyclosporine (Neoral, Sandimmune); rifampin (Rifadin, Rimactane); spironolactone (Aldactone); and telaprevir (Incivek). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Other medications may also interact with atorvastatin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you have liver disease. Your doctor will order laboratory tests to see how well your liver is working even if you do not think you have liver disease. Your doctor will probably tell you not to take atorvastatin if you have or have had liver disease or if the tests show you may be developing liver disease.

  • tell your doctor if you drink more than 2 alcoholic beverages daily, if you are 65 years of age or older, if you have ever had liver disease, and if you have or have ever had muscle aches or weakness; diabetes, seizures, low blood pressure, or thyroid or kidney disease.

    • tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are taking atorvastatin. Talk to your doctor about birth control methods that you can use during your treatment. If you become pregnant while taking atorvastatin, stop taking atorvastatin and call your doctor immediately. Atorvastatin may harm the fetus.

    • do not breast-feed while you are taking this medication.

  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking atorvastatin. If you are hospitalized due to serious injury or infection, tell the doctor who treats you that you are taking atorvastatin.

  • ask your doctor about the safe use of alcoholic beverages while you are taking atorvastatin. Alcohol can increase the risk of serious side effects.

Eat a low-fat, low-cholesterol diet. Be sure to follow all exercise and dietary recommendations made by your doctor or dietitian. You can also visit the National Cholesterol Education Program (NCEP) website for additional dietary information at http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Avoid drinking large amounts [more than 1.2 liter (approximately 1 quart) per day] of grapefruit juice while taking atorvastatin.

Take the missed dose as soon as you remember it. However, if it is less than 12 hours until your next scheduled dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Atorvastatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • diarrhea

    • heartburn

    • gas

    • joint pain

    • forgetfulness or memory loss

    • confusion

  • Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor or get emergency medical help immediately:

    • muscle pain, tenderness, or weakness

    • lack of energy

    • fever

    • chest pain

    • nausea

    • extreme tiredness

    • weakness

    • unusual bleeding or bruising

    • loss of appetite

    • pain in the upper right part of the stomach

    • flu-like symptoms

    • dark colored urine

    • yellowing of the skin or eyes

    • rash

    • hives

    • itching

    • difficulty breathing or swallowing

    • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

    • hoarseness

  • Atorvastatin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests during your treatment , especially if you develop symptoms of liver damage.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking atorvastatin.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • Caduet® (containing Amlodipine, Atorvastatin)
  • Liptruzet® (containing Atorvastatin, Ezetimibe)

Drug Interaction
Repaglinide Repaglinide The metabolism of Atorvastatin can be decreased when combined with Repaglinide.
Montelukast Montelukast The metabolism of Atorvastatin can be decreased when combined with Montelukast.
Leflunomide Leflunomide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Atorvastatin is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Atorvastatin can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Atorvastatin can be decreased when combined with Nevirapine.
Alendronate Alendronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Alendronic acid is combined with Atorvastatin.
Candesartan Candesartan The metabolism of Atorvastatin can be decreased when combined with Candesartan.
Cilostazol Cilostazol The metabolism of Cilostazol can be decreased when combined with Atorvastatin.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Atorvastatin.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The serum concentration of Atorvastatin can be increased when it is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The excretion of Atorvastatin can be decreased when combined with Conjugated estrogens.
Fenofibrate Fenofibrate Fenofibrate may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Methylergonovine Methylergonovine The metabolism of Atorvastatin can be decreased when combined with Methylergometrine.
Nafarelin Nafarelin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nafarelin is combined with Atorvastatin.
Paregoric Paregoric The metabolism of Atorvastatin can be decreased when combined with Morphine.
Ranitidine Ranitidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ranitidine is combined with Atorvastatin.
Reserpine Reserpine Reserpine may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Sumatriptan Sumatriptan The excretion of Sumatriptan can be decreased when combined with Atorvastatin.
Tacrolimus Tacrolimus The metabolism of Atorvastatin can be decreased when combined with Tacrolimus.
Triamcinolone Triamcinolone The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Triamcinolone is combined with Atorvastatin.
Fluconazole Injection Fluconazole Injection The metabolism of Atorvastatin can be decreased when combined with Fluconazole.
Metoclopramide Injection Metoclopramide Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Atorvastatin is combined with Metoclopramide.
Metronidazole Injection Metronidazole Injection The metabolism of Atorvastatin can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The metabolism of Atorvastatin can be decreased when combined with Morphine.
Pamidronate Injection Pamidronate Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Pamidronic acid is combined with Atorvastatin.
Zidovudine Injection Zidovudine Injection The metabolism of Atorvastatin can be decreased when combined with Zidovudine.
Cyclosporine Cyclosporine The excretion of Atorvastatin can be decreased when combined with Cyclosporine.
Ondansetron Ondansetron The metabolism of Atorvastatin can be decreased when combined with Ondansetron.
Torsemide Torsemide The metabolism of Atorvastatin can be decreased when combined with Torasemide.
Eprosartan Eprosartan The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Eprosartan is combined with Atorvastatin.
Hydroxychloroquine Hydroxychloroquine The metabolism of Hydroxychloroquine can be decreased when combined with Atorvastatin.
Oxcarbazepine Oxcarbazepine The metabolism of Atorvastatin can be decreased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole The excretion of Atorvastatin can be decreased when combined with Pantoprazole.
Risedronate Risedronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Risedronic acid is combined with Atorvastatin.
Sevelamer Sevelamer Sevelamer can cause a decrease in the absorption of Atorvastatin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Telmisartan Telmisartan Telmisartan may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Zaleplon Zaleplon The metabolism of Atorvastatin can be decreased when combined with Zaleplon.
Anakinra Anakinra The metabolism of Atorvastatin can be increased when combined with Anakinra.
Etanercept Injection Etanercept Injection The metabolism of Atorvastatin can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Atorvastatin can be increased when combined with Modafinil.
Sirolimus Sirolimus The risk or severity of adverse effects can be increased when Sirolimus is combined with Atorvastatin.
Dutasteride Dutasteride The metabolism of Dutasteride can be decreased when combined with Atorvastatin.
Epinephrine Injection Epinephrine Injection The metabolism of Atorvastatin can be decreased when combined with Epinephrine.
Eplerenone Eplerenone The metabolism of Atorvastatin can be decreased when combined with Eplerenone.
Olmesartan Olmesartan Olmesartan may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Zonisamide Zonisamide The metabolism of Atorvastatin can be decreased when combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Atorvastatin can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Atorvastatin.
Atazanavir Atazanavir The serum concentration of Atorvastatin can be increased when it is combined with Atazanavir.
Almotriptan Almotriptan The metabolism of Atorvastatin can be decreased when combined with Almotriptan.
Mefloquine Mefloquine The metabolism of Atorvastatin can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin Atorvastatin may decrease the excretion rate of Rosuvastatin which could result in a higher serum level.
Vardenafil Vardenafil The metabolism of Atorvastatin can be decreased when combined with Vardenafil.
Aprepitant Aprepitant The metabolism of Atorvastatin can be decreased when combined with Aprepitant.
Tegaserod Tegaserod The metabolism of Atorvastatin can be decreased when combined with Tegaserod.
Tadalafil Tadalafil The metabolism of Atorvastatin can be decreased when combined with Tadalafil.
Progesterone Progesterone Progesterone may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Apomorphine Injection Apomorphine Injection The metabolism of Atorvastatin can be decreased when combined with Apomorphine.
Infliximab Injection Infliximab Injection The metabolism of Atorvastatin can be increased when combined with Infliximab.
Rifaximin Rifaximin The metabolism of Atorvastatin can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Atorvastatin can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Atorvastatin can be decreased when combined with Norethisterone.
Tinidazole Tinidazole Tinidazole may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Bosentan Bosentan The serum concentration of Atorvastatin can be decreased when it is combined with Bosentan.
Erlotinib Erlotinib The metabolism of Atorvastatin can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone The metabolism of Atorvastatin can be decreased when combined with Eszopiclone.
Ganciclovir Ganciclovir The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ganciclovir is combined with Atorvastatin.
Voriconazole Voriconazole The risk or severity of myopathy can be increased when Voriconazole is combined with Atorvastatin.
Ibandronate Ibandronate The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ibandronate is combined with Atorvastatin.
Fentanyl Fentanyl The metabolism of Atorvastatin can be decreased when combined with Fentanyl.
Deferasirox Deferasirox The metabolism of Atorvastatin can be decreased when combined with Deferasirox.
Tipranavir Tipranavir The serum concentration of Atorvastatin can be increased when it is combined with Tipranavir.
Ranolazine Ranolazine The serum concentration of Atorvastatin can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Atorvastatin can be increased when combined with Abatacept.
Imatinib Imatinib The metabolism of Atorvastatin can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Atorvastatin.
Gefitinib Gefitinib The metabolism of Atorvastatin can be decreased when combined with Gefitinib.
Paliperidone Paliperidone The metabolism of Paliperidone can be decreased when combined with Atorvastatin.
Posaconazole Posaconazole The serum concentration of Atorvastatin can be increased when it is combined with Posaconazole.
Primaquine Primaquine The metabolism of Atorvastatin can be decreased when combined with Primaquine.
Darunavir Darunavir The metabolism of Atorvastatin can be decreased when combined with Darunavir.
Nabilone Nabilone The metabolism of Atorvastatin can be decreased when combined with Nabilone.
Sorafenib Sorafenib The metabolism of Atorvastatin can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Atorvastatin can be decreased when combined with Sunitinib.
Lapatinib Lapatinib The metabolism of Atorvastatin can be decreased when combined with Lapatinib.
Dasatinib Dasatinib The metabolism of Atorvastatin can be decreased when combined with Dasatinib.
Armodafinil Armodafinil The metabolism of Atorvastatin can be increased when combined with Armodafinil.
Ivermectin Ivermectin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Ivermectin is combined with Atorvastatin.
Temsirolimus Temsirolimus The risk or severity of adverse effects can be increased when Temsirolimus is combined with Atorvastatin.
Nilotinib Nilotinib The metabolism of Atorvastatin can be decreased when combined with Nilotinib.
Raltegravir Raltegravir The risk or severity of myopathy and rhabdomyolysis can be increased when Raltegravir is combined with Atorvastatin.
Bexarotene Bexarotene The serum concentration of Atorvastatin can be decreased when it is combined with Bexarotene.
Budesonide Budesonide The metabolism of Atorvastatin can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Atorvastatin can be decreased when combined with Chloramphenicol.
Etravirine Etravirine The serum concentration of Atorvastatin can be decreased when it is combined with Etravirine.
Mitoxantrone Injection Mitoxantrone Injection The metabolism of Atorvastatin can be decreased when combined with Mitoxantrone.
Desvenlafaxine Desvenlafaxine The metabolism of Atorvastatin can be decreased when combined with Desvenlafaxine.
Tretinoin Tretinoin The metabolism of Atorvastatin can be decreased when combined with Tretinoin.
Pilocarpine Pilocarpine The metabolism of Atorvastatin can be decreased when combined with Pilocarpine.
Certolizumab Injection Certolizumab Injection The metabolism of Atorvastatin can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The risk or severity of adverse effects can be increased when Ixabepilone is combined with Atorvastatin.
Irinotecan Injection Irinotecan Injection The excretion of Atorvastatin can be decreased when combined with Irinotecan.
Daptomycin Injection Daptomycin Injection The risk or severity of myopathy can be increased when Atorvastatin is combined with Daptomycin.
Praziquantel Praziquantel The metabolism of Atorvastatin can be decreased when combined with Praziquantel.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Atorvastatin.
Naltrexone Injection Naltrexone Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Naltrexone is combined with Atorvastatin.
Eltrombopag Eltrombopag The metabolism of Atorvastatin can be decreased when combined with Eltrombopag.
Milnacipran Milnacipran The metabolism of Atorvastatin can be decreased when combined with Milnacipran.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Atorvastatin.
Everolimus Everolimus The risk or severity of adverse effects can be increased when Everolimus is combined with Atorvastatin.
Dronedarone Dronedarone The metabolism of Atorvastatin can be decreased when combined with Dronedarone.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Atorvastatin.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be decreased when combined with Atorvastatin.
Topotecan Topotecan The metabolism of Atorvastatin can be decreased when combined with Topotecan.
Golimumab Injection Golimumab Injection The metabolism of Atorvastatin can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Atorvastatin can be decreased when combined with Pazopanib.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Atorvastatin.
Levonorgestrel Levonorgestrel The metabolism of Atorvastatin can be decreased when combined with Levonorgestrel.
Tocilizumab Injection Tocilizumab Injection The metabolism of Atorvastatin can be increased when combined with Tocilizumab.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Atorvastatin.
Acetaminophen Injection Acetaminophen Injection The metabolism of Atorvastatin can be decreased when combined with Acetaminophen.
Denileukin Diftitox Injection Denileukin Diftitox Injection The metabolism of Atorvastatin can be decreased when combined with Aldesleukin.
Linagliptin Linagliptin The metabolism of Atorvastatin can be decreased when combined with Linagliptin.
Rilpivirine Rilpivirine The serum concentration of Atorvastatin can be increased when it is combined with Rilpivirine.
Telaprevir Telaprevir The metabolism of Atorvastatin can be decreased when combined with Glecaprevir.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Atorvastatin can be decreased when combined with Cyclophosphamide.
Abiraterone Abiraterone The metabolism of Atorvastatin can be decreased when combined with Abiraterone.
Rivaroxaban Rivaroxaban The metabolism of Rivaroxaban can be decreased when combined with Atorvastatin.
Ticagrelor Ticagrelor The serum concentration of Atorvastatin can be increased when it is combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Atorvastatin can be decreased when combined with Brentuximab vedotin.
Vemurafenib Vemurafenib The metabolism of Atorvastatin can be decreased when combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Atorvastatin can be decreased when combined with Vismodegib.
Ivacaftor Ivacaftor The metabolism of Atorvastatin can be decreased when combined with Ivacaftor.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Atorvastatin.
Crizotinib Crizotinib The metabolism of Atorvastatin can be decreased when combined with Crizotinib.
Cabergoline Cabergoline The metabolism of Atorvastatin can be decreased when combined with Cabergoline.
Naloxone Injection Naloxone Injection The metabolism of Atorvastatin can be decreased when combined with Naloxone.
Ambrisentan Ambrisentan The excretion of Ambrisentan can be decreased when combined with Atorvastatin.
Iloprost Iloprost The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Atorvastatin is combined with Iloprost.
Enzalutamide Enzalutamide The metabolism of Atorvastatin can be decreased when combined with Enzalutamide.
Regorafenib Regorafenib The metabolism of Atorvastatin can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The metabolism of Atorvastatin can be decreased when combined with Bosutinib.
Teriflunomide Teriflunomide The metabolism of Atorvastatin can be decreased when combined with Teriflunomide.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Atorvastatin can be decreased when combined with Cabozantinib.
Ponatinib Ponatinib The metabolism of Atorvastatin can be decreased when combined with Ponatinib.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Atorvastatin can be decreased when combined with Trastuzumab emtansine.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Atorvastatin.
Dabrafenib Dabrafenib The metabolism of Atorvastatin can be decreased when combined with Dabrafenib.
Trametinib Trametinib The metabolism of Atorvastatin can be decreased when combined with Trametinib.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Atorvastatin.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Atorvastatin.
Perampanel Perampanel The metabolism of Perampanel can be decreased when combined with Atorvastatin.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Atorvastatin.
Lomitapide Lomitapide The metabolism of Atorvastatin can be decreased when combined with Lomitapide.
Ketorolac Injection Ketorolac Injection The metabolism of Atorvastatin can be decreased when combined with Ketorolac.
Simeprevir Simeprevir The serum concentration of Atorvastatin can be increased when it is combined with Simeprevir.
Apremilast Apremilast The metabolism of Atorvastatin can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Atorvastatin can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Atorvastatin can be decreased when combined with Siltuximab.
Idelalisib Idelalisib The metabolism of Atorvastatin can be decreased when combined with Idelalisib.
Testosterone Injection Testosterone Injection The metabolism of Atorvastatin can be decreased when combined with Testosterone.
Olaparib Olaparib The metabolism of Atorvastatin can be decreased when combined with Olaparib.
Caspofungin Injection Caspofungin Injection The excretion of Atorvastatin can be decreased when combined with Caspofungin.
Riociguat Riociguat The metabolism of Riociguat can be decreased when combined with Atorvastatin.
Lanreotide Injection Lanreotide Injection The metabolism of Atorvastatin can be decreased when combined with Lanreotide.
Secukinumab Injection Secukinumab Injection The metabolism of Atorvastatin can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Atorvastatin can be decreased when combined with Risperidone.
Palbociclib Palbociclib The metabolism of Atorvastatin can be decreased when combined with Palbociclib.
Lenvatinib Lenvatinib The metabolism of Atorvastatin can be decreased when combined with Lenvatinib.
Haloperidol Injection Haloperidol Injection The metabolism of Atorvastatin can be decreased when combined with Haloperidol.
Deoxycholic Acid Injection Deoxycholic Acid Injection Deoxycholic acid may increase the excretion rate of Atorvastatin which could result in a lower serum level and potentially a reduction in efficacy.
Isavuconazonium Injection Isavuconazonium Injection The risk or severity of myopathy can be increased when Isavuconazonium is combined with Atorvastatin.
Daclatasvir Daclatasvir The serum concentration of Atorvastatin can be increased when it is combined with Daclatasvir.
Ziprasidone Injection Ziprasidone Injection The metabolism of Atorvastatin can be decreased when combined with Ziprasidone.
Eluxadoline Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Atorvastatin.
Cobimetinib Cobimetinib The excretion of Cobimetinib can be decreased when combined with Atorvastatin.
Trabectedin Injection Trabectedin Injection The risk or severity of myopathy and rhabdomyolysis can be increased when Atorvastatin is combined with Trabectedin.
Osimertinib Osimertinib The metabolism of Atorvastatin can be decreased when combined with Osimertinib.
Rifapentine Rifapentine The metabolism of Atorvastatin can be increased when combined with Rifapentine.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The metabolism of Atorvastatin can be decreased when combined with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The metabolism of Atorvastatin can be decreased when combined with Dexamethasone.
Venetoclax Venetoclax The metabolism of Atorvastatin can be decreased when combined with Venetoclax.
Cobicistat Cobicistat The serum concentration of Atorvastatin can be increased when it is combined with Cobicistat.
Selexipag Selexipag The metabolism of Selexipag can be decreased when combined with Atorvastatin.
Rucaparib Rucaparib The metabolism of Atorvastatin can be decreased when combined with Rucaparib.
Ribociclib Ribociclib The metabolism of Atorvastatin can be decreased when combined with Ribociclib.
Brigatinib Brigatinib The metabolism of Brigatinib can be decreased when combined with Atorvastatin.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Atorvastatin.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Atorvastatin.
Deflazacort Deflazacort The metabolism of Atorvastatin can be increased when combined with Deflazacort.
Safinamide Safinamide The metabolism of Safinamide can be decreased when combined with Atorvastatin.
Sarilumab Injection Sarilumab Injection The metabolism of Atorvastatin can be decreased when combined with Sarilumab.
Midostaurin Midostaurin The metabolism of Atorvastatin can be decreased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Atorvastatin can be decreased when combined with Enasidenib.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Atorvastatin can be decreased when combined with Fosaprepitant.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Atorvastatin.
Acalabrutinib Acalabrutinib The metabolism of Atorvastatin can be decreased when combined with Acalabrutinib.
Letermovir Letermovir The metabolism of Atorvastatin can be decreased when combined with Letermovir.
Ertugliflozin Ertugliflozin The metabolism of Atorvastatin can be decreased when combined with Ertugliflozin.
Buprenorphine Injection Buprenorphine Injection The metabolism of Atorvastatin can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide The metabolism of Apalutamide can be decreased when combined with Atorvastatin.
Penicillamine Penicillamine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Penicillamine is combined with Atorvastatin.
Fostamatinib Fostamatinib The metabolism of Atorvastatin can be decreased when combined with Fostamatinib.
Avatrombopag Avatrombopag The metabolism of Atorvastatin can be increased when combined with Avatrombopag.
Baricitinib Baricitinib The excretion of Atorvastatin can be decreased when combined with Baricitinib.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Atorvastatin.
Doravirine Doravirine The metabolism of Doravirine can be decreased when combined with Atorvastatin.
Cannabidiol Cannabidiol The metabolism of Atorvastatin can be decreased when combined with Cannabidiol.
Dacomitinib Dacomitinib The metabolism of Atorvastatin can be decreased when combined with Dacomitinib.
Stiripentol Stiripentol The metabolism of Atorvastatin can be decreased when combined with Stiripentol.
Glasdegib Glasdegib The metabolism of Glasdegib can be decreased when combined with Atorvastatin.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Atorvastatin.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Atorvastatin.
Rifamycin Rifamycin The metabolism of Atorvastatin can be decreased when combined with Rifamycin.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Atorvastatin can be increased when combined with Emapalumab.
Alpelisib Alpelisib The metabolism of Atorvastatin can be decreased when combined with Alpelisib.
Cladribine Cladribine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cladribine is combined with Atorvastatin.
Selinexor Selinexor The excretion of Atorvastatin can be decreased when combined with Selinexor.
Triclabendazole Triclabendazole The metabolism of Atorvastatin can be decreased when combined with Triclabendazole.
Pexidartinib Pexidartinib The metabolism of Atorvastatin can be decreased when combined with Pexidartinib.
Istradefylline Istradefylline The serum concentration of Istradefylline can be increased when it is combined with Atorvastatin.
Pitolisant Pitolisant The serum concentration of Atorvastatin can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The excretion of Atorvastatin can be decreased when combined with Fedratinib.
Phenytoin Injection Phenytoin Injection The serum concentration of Atorvastatin can be decreased when it is combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The serum concentration of Atorvastatin can be decreased when it is combined with Fosphenytoin.
Bempedoic Acid Bempedoic Acid The excretion of Atorvastatin can be decreased when combined with Bempedoic acid.
Cenobamate Cenobamate The metabolism of Cenobamate can be decreased when combined with Atorvastatin.
Ozanimod Ozanimod The metabolism of Ozanimod can be decreased when combined with Atorvastatin.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Atorvastatin.
Rimegepant Rimegepant The metabolism of Rimegepant can be increased when combined with Atorvastatin.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Atorvastatin.
Remdesivir Injection Remdesivir Injection The metabolism of Remdesivir can be decreased when combined with Atorvastatin.
Selpercatinib Selpercatinib The serum concentration of Atorvastatin can be decreased when it is combined with Selpercatinib.
Capmatinib Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Atorvastatin.
Lemborexant Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Atorvastatin.
Fostemsavir Fostemsavir The serum concentration of Atorvastatin can be increased when it is combined with Fostemsavir.
Octreotide Octreotide The metabolism of Atorvastatin can be decreased when combined with Octreotide.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection Atorvastatin may decrease the excretion rate of Belantamab mafodotin which could result in a higher serum level.
Pralsetinib Pralsetinib The metabolism of Atorvastatin can be decreased when combined with Pralsetinib.
Opicapone Opicapone The metabolism of Atorvastatin can be decreased when combined with Opicapone.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Atorvastatin can be decreased when it is combined with Satralizumab.
Theophylline Theophylline The metabolism of Atorvastatin can be decreased when combined with Theophylline.
Indomethacin Indomethacin Indomethacin may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Mefenamic Acid Mefenamic Acid The metabolism of Atorvastatin can be decreased when combined with Mefenamic acid.
Naproxen Naproxen The metabolism of Atorvastatin can be decreased when combined with Naproxen.
Trazodone Trazodone The metabolism of Atorvastatin can be decreased when combined with Trazodone.
Isotretinoin Isotretinoin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Isotretinoin is combined with Atorvastatin.
Phenobarbital Phenobarbital The metabolism of Atorvastatin can be increased when combined with Phenobarbital.
Methotrexate Injection Methotrexate Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Atorvastatin is combined with Methotrexate.
Primidone Primidone The metabolism of Atorvastatin can be increased when combined with Primidone.
Chlorpromazine Chlorpromazine Chlorpromazine may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Diazepam Diazepam The metabolism of Atorvastatin can be decreased when combined with Diazepam.
Bromocriptine Bromocriptine The metabolism of Atorvastatin can be decreased when combined with Bromocriptine.
Tranylcypromine Tranylcypromine The metabolism of Atorvastatin can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Atorvastatin can be decreased when combined with Phenelzine.
Procarbazine Procarbazine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Atorvastatin is combined with Procarbazine.
Tetracycline Tetracycline The metabolism of Atorvastatin can be decreased when combined with Tetracycline.
Minocycline Minocycline The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Minocycline is combined with Atorvastatin.
Dapsone Dapsone The metabolism of Atorvastatin can be decreased when combined with Dapsone.
Sulfadiazine Sulfadiazine The metabolism of Atorvastatin can be decreased when combined with Sulfadiazine.
Oxycodone Oxycodone The metabolism of Atorvastatin can be decreased when combined with Oxycodone.
Methadone Methadone The metabolism of Atorvastatin can be decreased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Atorvastatin can be decreased when combined with Oxybutynin.
Colestipol Colestipol Colestipol can cause a decrease in the absorption of Atorvastatin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ibuprofen Ibuprofen The metabolism of Atorvastatin can be decreased when combined with Ibuprofen.
Orphenadrine Orphenadrine The metabolism of Atorvastatin can be decreased when combined with Orphenadrine.
Sulfasalazine Sulfasalazine The excretion of Atorvastatin can be decreased when combined with Sulfasalazine.
Hydrocortisone Hydrocortisone The metabolism of Atorvastatin can be increased when combined with Hydrocortisone.
Doxorubicin Doxorubicin The metabolism of Atorvastatin can be decreased when combined with Doxorubicin.
Cytarabine Cytarabine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Cytarabine is combined with Atorvastatin.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Atorvastatin.
Methyldopa Methyldopa The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Methyldopa is combined with Atorvastatin.
Clonidine Clonidine The metabolism of Atorvastatin can be decreased when combined with Clonidine.
Hydralazine Hydralazine The metabolism of Atorvastatin can be decreased when combined with Hydralazine.
Cimetidine Cimetidine The metabolism of Atorvastatin can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Warfarin can be decreased when combined with Atorvastatin.
Loperamide Loperamide The metabolism of Atorvastatin can be decreased when combined with Loperamide.
Daunorubicin Daunorubicin The metabolism of Atorvastatin can be decreased when combined with Daunorubicin.
Nitrofurantoin Nitrofurantoin Nitrofurantoin may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Griseofulvin Griseofulvin The metabolism of Atorvastatin can be increased when combined with Griseofulvin.
Digoxin Digoxin The serum concentration of Digoxin can be increased when it is combined with Atorvastatin.
Chloroquine Chloroquine The metabolism of Atorvastatin can be decreased when combined with Chloroquine.
Quinine Quinine The risk or severity of myopathy and rhabdomyolysis can be increased when Quinine is combined with Atorvastatin.
Sulfinpyrazone Sulfinpyrazone The metabolism of Atorvastatin can be decreased when combined with Sulfinpyrazone.
Clindamycin Injection Clindamycin Injection The risk or severity of adverse effects can be increased when Atorvastatin is combined with Clindamycin.
Secobarbital Secobarbital The metabolism of Atorvastatin can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Atorvastatin can be decreased when combined with Desipramine.
Amitriptyline Amitriptyline The metabolism of Atorvastatin can be decreased when combined with Amitriptyline.
Imipramine Imipramine The metabolism of Atorvastatin can be decreased when combined with Imipramine.
Probenecid Probenecid The metabolism of Atorvastatin can be increased when combined with Probenecid.
Quinidine Quinidine The risk or severity of myopathy and rhabdomyolysis can be increased when Quinidine is combined with Atorvastatin.
Procainamide Procainamide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Procainamide is combined with Atorvastatin.
Isoniazid Isoniazid The metabolism of Atorvastatin can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Atorvastatin can be increased when combined with Rifampicin.
Valproic Acid Valproic Acid The metabolism of Atorvastatin can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Atorvastatin can be decreased when combined with Tamoxifen.
Levothyroxine Levothyroxine The metabolism of Levothyroxine can be decreased when combined with Atorvastatin.
Liothyronine Liothyronine The excretion of Liothyronine can be decreased when combined with Atorvastatin.
Methimazole Methimazole The metabolism of Atorvastatin can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Propylthiouracil is combined with Atorvastatin.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Atorvastatin.
Dextromethorphan Dextromethorphan The metabolism of Atorvastatin can be decreased when combined with Dextromethorphan.
Dinoprostone Dinoprostone The excretion of Dinoprostone can be decreased when combined with Atorvastatin.
Niacin Niacin The risk or severity of myopathy and rhabdomyolysis can be increased when Niacin is combined with Atorvastatin.
Baclofen Baclofen The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Atorvastatin.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Atorvastatin.
Danazol Danazol The serum concentration of Atorvastatin can be increased when it is combined with Danazol.
Disulfiram Disulfiram Disulfiram may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Atorvastatin can be decreased when combined with Propranolol.
Spironolactone Spironolactone The metabolism of Atorvastatin can be decreased when combined with Spironolactone.
Amphotericin B Injection Amphotericin B Injection The metabolism of Atorvastatin can be decreased when combined with Amphotericin B.
Cholestyramine Resin Cholestyramine Resin Cholestyramine can cause a decrease in the absorption of Atorvastatin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Fluorouracil Injection Fluorouracil Injection The metabolism of Atorvastatin can be decreased when combined with Fluorouracil.
Colchicine Colchicine The metabolism of Atorvastatin can be decreased when combined with Colchicine.
Cefaclor Cefaclor Cefaclor may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Acetazolamide Acetazolamide The metabolism of Atorvastatin can be decreased when combined with Acetazolamide.
Nystatin Nystatin The excretion of Atorvastatin can be decreased when combined with Nystatin.
Ketoconazole Ketoconazole The serum concentration of Atorvastatin can be increased when it is combined with Ketoconazole.
Vincristine Injection Vincristine Injection The metabolism of Atorvastatin can be decreased when combined with Vincristine.
Captopril Captopril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Atorvastatin is combined with Captopril.
Dipyridamole Dipyridamole Dipyridamole may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Vinblastine Vinblastine The metabolism of Atorvastatin can be decreased when combined with Vinblastine.
Hydroxyzine Hydroxyzine The metabolism of Atorvastatin can be decreased when combined with Hydroxyzine.
Alprazolam Alprazolam The metabolism of Atorvastatin can be decreased when combined with Alprazolam.
Triazolam Triazolam The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Triazolam is combined with Atorvastatin.
Trimethoprim Trimethoprim The metabolism of Atorvastatin can be decreased when combined with Trimethoprim.
Diltiazem Diltiazem The serum concentration of Diltiazem can be increased when it is combined with Atorvastatin.
Nifedipine Nifedipine Nifedipine may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Verapamil Verapamil The serum concentration of Verapamil can be increased when it is combined with Atorvastatin.
Atenolol Atenolol Atenolol may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Piroxicam Piroxicam The metabolism of Atorvastatin can be decreased when combined with Piroxicam.
Bumetanide Bumetanide The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Bumetanide is combined with Atorvastatin.
Etoposide Etoposide The metabolism of Atorvastatin can be decreased when combined with Etoposide.
Glyburide Glyburide The metabolism of Atorvastatin can be decreased when combined with Glyburide.
Glipizide Glipizide Glipizide may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Pentamidine Injection Pentamidine Injection The metabolism of Atorvastatin can be decreased when combined with Pentamidine.
Leuprolide Injection Leuprolide Injection The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Atorvastatin.
Gemfibrozil Gemfibrozil The risk or severity of rhabdomyolysis, myoglobinuria, and elevated creatine kinase (CPK) can be increased when Gemfibrozil is combined with Atorvastatin.
Ketoprofen Ketoprofen The metabolism of Ketoprofen can be decreased when combined with Atorvastatin.
Pimozide Pimozide The metabolism of Atorvastatin can be decreased when combined with Pimozide.
Enalapril Enalapril The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Atorvastatin is combined with Enalapril.
Flurbiprofen Flurbiprofen The metabolism of Atorvastatin can be decreased when combined with Flurbiprofen.
Amiodarone Amiodarone The serum concentration of Atorvastatin can be increased when it is combined with Amiodarone.
Buspirone Buspirone The metabolism of Atorvastatin can be decreased when combined with Buspirone.
Lovastatin Lovastatin The metabolism of Atorvastatin can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The metabolism of Atorvastatin can be decreased when combined with Ciprofloxacin.
Diclofenac Diclofenac The metabolism of Atorvastatin can be decreased when combined with Diclofenac.
Clozapine Clozapine The metabolism of Atorvastatin can be decreased when combined with Clozapine.
Ofloxacin Ofloxacin The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Atorvastatin is combined with Ofloxacin.
Clarithromycin Clarithromycin The risk or severity of rhabdomyolysis can be increased when Clarithromycin is combined with Atorvastatin.
Felodipine Felodipine The metabolism of Atorvastatin can be decreased when combined with Felodipine.
Pravastatin Pravastatin Atorvastatin may decrease the excretion rate of Pravastatin which could result in a higher serum level.
Simvastatin Simvastatin The metabolism of Atorvastatin can be decreased when combined with Simvastatin.
Teniposide Injection Teniposide Injection The metabolism of Atorvastatin can be decreased when combined with Teniposide.
Itraconazole Itraconazole The serum concentration of Atorvastatin can be increased when it is combined with Itraconazole.
Rifabutin Rifabutin The metabolism of Atorvastatin can be increased when combined with Rifabutin.
Isradipine Isradipine The metabolism of Atorvastatin can be decreased when combined with Isradipine.
Omeprazole Omeprazole The metabolism of Atorvastatin can be decreased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Atorvastatin can be decreased when combined with Cisapride.
Fluvastatin Fluvastatin The metabolism of Atorvastatin can be decreased when combined with Fluvastatin.
Nizatidine Nizatidine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Nizatidine is combined with Atorvastatin.
Stavudine Stavudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Stavudine is combined with Atorvastatin.
Fluvoxamine Fluvoxamine The metabolism of Atorvastatin can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Atorvastatin can be decreased when combined with Nefazodone.
Lamotrigine Lamotrigine The metabolism of Atorvastatin can be increased when combined with Lamotrigine.
Losartan Losartan The metabolism of Atorvastatin can be decreased when combined with Losartan.
Lansoprazole Lansoprazole The metabolism of Atorvastatin can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Atorvastatin can be decreased when combined with Ifosfamide.
Nicardipine Nicardipine The metabolism of Atorvastatin can be decreased when combined with Nicardipine.
Ticlopidine Ticlopidine The metabolism of Atorvastatin can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The metabolism of Atorvastatin can be decreased when combined with Saquinavir.
Metformin Metformin Metformin may increase the hypolipidaemic activities of Atorvastatin.
Nisoldipine Nisoldipine The metabolism of Atorvastatin can be decreased when combined with Nisoldipine.
Lamivudine Lamivudine The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Lamivudine is combined with Atorvastatin.
Glimepiride Glimepiride Glimepiride may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Anastrozole Anastrozole The metabolism of Anastrozole can be decreased when combined with Atorvastatin.
Indinavir Indinavir The metabolism of Atorvastatin can be decreased when combined with Indinavir.
Ritonavir Ritonavir The metabolism of Atorvastatin can be decreased when combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Atorvastatin can be decreased when combined with Docetaxel.
Zafirlukast Zafirlukast The metabolism of Atorvastatin can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine The metabolism of Atorvastatin can be decreased when combined with Mirtazapine.
Valsartan Valsartan The excretion of Atorvastatin can be decreased when combined with Valsartan.
Nelfinavir Nelfinavir The metabolism of Atorvastatin can be decreased when combined with Nelfinavir.
Fexofenadine Fexofenadine The excretion of Fexofenadine can be decreased when combined with Atorvastatin.
Azithromycin Azithromycin The risk or severity of myopathy and rhabdomyolysis can be increased when Azithromycin is combined with Atorvastatin.
Loratadine Loratadine The metabolism of Atorvastatin can be decreased when combined with Loratadine.
Nilutamide Nilutamide The metabolism of Atorvastatin can be decreased when combined with Nilutamide.
Flutamide Flutamide The metabolism of Atorvastatin can be decreased when combined with Flutamide.
Selegiline Selegiline The metabolism of Atorvastatin can be decreased when combined with Selegiline.
Bicalutamide Bicalutamide The metabolism of Atorvastatin can be decreased when combined with Bicalutamide.
Letrozole Letrozole The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Letrozole is combined with Atorvastatin.
Raloxifene Raloxifene The metabolism of Atorvastatin can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Atorvastatin can be decreased when combined with Irbesartan.
Finasteride Finasteride The metabolism of Finasteride can be decreased when combined with Atorvastatin.
Quetiapine Quetiapine The metabolism of Quetiapine can be decreased when combined with Atorvastatin.
Paroxetine Paroxetine The metabolism of Atorvastatin can be decreased when combined with Paroxetine.
Citalopram Citalopram The metabolism of Atorvastatin can be decreased when combined with Citalopram.
Efavirenz Efavirenz The serum concentration of Atorvastatin can be decreased when it is combined with Efavirenz.
Sildenafil Sildenafil The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Sildenafil is combined with Atorvastatin.
Pioglitazone Pioglitazone The metabolism of Pioglitazone can be decreased when combined with Atorvastatin.
Celecoxib Celecoxib Celecoxib may decrease the excretion rate of Atorvastatin which could result in a higher serum level.
Rosiglitazone Rosiglitazone The metabolism of Atorvastatin can be decreased when combined with Rosiglitazone.
Thalidomide Thalidomide The metabolism of Atorvastatin can be increased when combined with Thalidomide.
Colesevelam Colesevelam Colesevelam can cause a decrease in the absorption of Atorvastatin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nateglinide Nateglinide The metabolism of Atorvastatin can be decreased when combined with Nateglinide.
Rabeprazole Rabeprazole The metabolism of Atorvastatin can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Atorvastatin can be decreased when combined with Terbinafine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists