Ondansetron

Generic name: Pronounced as (on dan' se tron)
Brand names
  • Zofran®
  • Zofran® ODT
  • Zuplenz®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 01/15/2022

Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.

Ondansetron comes as a tablet, a rapidly disintegrating (dissolving) tablet, film, and an oral solution (liquid) to take by mouth. The first dose of ondansetron is usually taken 30 minutes before the start of chemotherapy, 1 to 2 hours before the start of radiation therapy, or 1 hour before surgery. Additional doses are sometimes taken one to three times a day during chemotherapy or radiation therapy and for 1 to 2 days after the end of treatment. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ondansetron exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Do not chew the film.

If you are taking the rapidly disintegrating tablet, remove the tablet from the package just before you take your dose. To open the package, do not try to push the tablet through the foil backing of the blister. Instead, use dry hands to peel back the foil backing. Gently remove the tablet and immediately place the tablet on the top of your tongue. The tablet will dissolve in a few seconds and can be swallowed with saliva.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Before taking ondansetron,

  • tell your doctor and pharmacist if you are allergic to ondansetron, alosetron (Lotronex), dolasetron (Anzemet), granisetron (Kytril), palonosetron (Aloxi, in Akynzeo), any other medications, or any of the ingredients in ondansetron products. Ask your pharmacist for a list of the ingredients.

  • tell your doctor if you are receiving apomorphine (Apokyn). Your doctor will probably tell you not to take ondansetron if you are receiving this medication.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: certain medications for seizures such as carbamazepine (Carbatrol, Epitol, Equetro, Tegretol) or phenytoin (Dilantin); clarithromycin (Biaxin, in Prevpac); erythromycin (E.E.S., Erythrocin, others); fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Onsolis, Subsys); lithium (Lithobid); medications for irregular heart beat; medications for mental illness; medications to treat migraines such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); methylene blue; mirtazapine (Remeron); monoamine oxidase (MAO) inhibitors including isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); moxifloxacin (Avelox); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft); and tramadol (Conzip, Ultram, in Ultracet). Your doctor may need to change the doses of your medications or monitor you more carefully for side effects. Many other medications may also interact with ondansetron, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you or anyone in your family has or has ever had long QT syndrome (condition that increases the risk of developing an irregular heartbeat that may cause fainting or sudden death), or another type of irregular heart beat or heart rhythm problem, or if you have or have ever had low blood levels of magnesium or potassium in your blood, heart failure (HF; condition in which the heart cannot pump enough blood to other parts of the body), or liver disease.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking ondansetron, call your doctor.

  • if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that the orally disintegrating tablets contain aspartame that forms phenylalanine.

Unless your doctor tells you otherwise, continue your usual diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Ondansetron may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • headache

    • constipation

    • weakness

    • tiredness

    • chills

    • drowsiness

  • Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or seek emergency medical treatment:

    • blurred vision or vision loss

    • rash

    • hives

    • itching

    • swelling of the eyes, face, lips, tongue, throat, hands, feet, ankles, or lower legs

    • hoarseness

    • difficulty breathing or swallowing

    • chest pain

    • shortness of breath

    • dizziness, light-headedness, or fainting

    • fast, slow or irregular heartbeat

    • agitation

    • hallucinations (seeing things or hearing voices that do not exist)

    • fever

    • excessive sweating

    • confusion

    • nausea, vomiting, or diarrhea

    • loss of coordination

    • stiff or twitching muscles

    • seizures

    • coma (loss of consciousness)

  • Ondansetron may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets and rapidly disintegrating tablets away from light, at room temperature or in the refrigerator. Store the solution in the bottle upright at room temperature and away from light, excess heat, and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include:

  • sudden loss of vision for a short time

  • dizziness or lightheadedness

  • fainting

  • constipation

  • irregular heart beat

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The risk or severity of QTc prolongation can be increased when Moxifloxacin is combined with Ondansetron.
Montelukast Montelukast The metabolism of Ondansetron can be decreased when combined with Montelukast.
Leflunomide Leflunomide The metabolism of Leflunomide can be decreased when combined with Ondansetron.
Delavirdine Delavirdine The metabolism of Ondansetron can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Ondansetron can be decreased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Ondansetron.
Dolasetron Dolasetron The risk or severity of adverse effects can be increased when Dolasetron is combined with Ondansetron.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Ondansetron.
Anagrelide Anagrelide The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Anagrelide.
Candesartan Candesartan The metabolism of Ondansetron can be decreased when combined with Candesartan.
Cilostazol Cilostazol The risk or severity of QTc prolongation can be increased when Cilostazol is combined with Ondansetron.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Ondansetron.
Diphenoxylate Diphenoxylate The risk or severity of adverse effects can be increased when Ondansetron is combined with Diphenoxylate.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The metabolism of Ondansetron can be decreased when combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Conjugated estrogens can be decreased when combined with Ondansetron.
Fenofibrate Fenofibrate The metabolism of Ondansetron can be decreased when combined with Fenofibrate.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Ondansetron is combined with Guanfacine.
Naratriptan Naratriptan The risk or severity of adverse effects can be increased when Ondansetron is combined with Naratriptan.
Paregoric Paregoric The risk or severity of adverse effects can be increased when Morphine is combined with Ondansetron.
Penbutolol Penbutolol The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Acebutolol.
Pentazocine Pentazocine The risk or severity of adverse effects can be increased when Pentazocine is combined with Ondansetron.
Ranitidine Ranitidine The metabolism of Ranitidine can be decreased when combined with Ondansetron.
Reserpine Reserpine The risk or severity of adverse effects can be increased when Reserpine is combined with Ondansetron.
Rizatriptan Rizatriptan The risk or severity of adverse effects can be increased when Ondansetron is combined with Rizatriptan.
Sumatriptan Sumatriptan The risk or severity of adverse effects can be increased when Sumatriptan is combined with Ondansetron.
Tacrolimus Tacrolimus The metabolism of Tacrolimus can be decreased when combined with Ondansetron.
Tizanidine Tizanidine The metabolism of Tizanidine can be decreased when combined with Ondansetron.
Triamcinolone Triamcinolone The metabolism of Ondansetron can be increased when combined with Triamcinolone.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Ondansetron.
Famotidine Injection Famotidine Injection The risk or severity of QTc prolongation can be increased when Famotidine is combined with Ondansetron.
Fluconazole Injection Fluconazole Injection The metabolism of Ondansetron can be decreased when combined with Fluconazole.
Foscarnet Injection Foscarnet Injection The risk or severity of QTc prolongation can be increased when Foscarnet is combined with Ondansetron.
Hydromorphone Injection Hydromorphone Injection The risk or severity of adverse effects can be increased when Hydromorphone is combined with Ondansetron.
Levofloxacin Injection Levofloxacin Injection The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Levofloxacin.
Meperidine Injection Meperidine Injection The risk or severity of adverse effects can be increased when Meperidine is combined with Ondansetron.
Metoclopramide Injection Metoclopramide Injection The risk or severity of sedation can be increased when Metoclopramide is combined with Ondansetron.
Metronidazole Injection Metronidazole Injection The metabolism of Ondansetron can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The risk or severity of adverse effects can be increased when Morphine is combined with Ondansetron.
Zidovudine Injection Zidovudine Injection The metabolism of Ondansetron can be decreased when combined with Zidovudine.
Altretamine Altretamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Ondansetron.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Ondansetron.
Granisetron Granisetron The risk or severity of adverse effects can be increased when Granisetron is combined with Ondansetron.
Torsemide Torsemide The metabolism of Ondansetron can be decreased when combined with Torasemide.
Olanzapine Olanzapine The risk or severity of adverse effects can be increased when Olanzapine is combined with Ondansetron.
Alosetron Alosetron The metabolism of Alosetron can be decreased when combined with Ondansetron.
Dofetilide Dofetilide The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Dofetilide.
Entacapone Entacapone The risk or severity of adverse effects can be increased when Entacapone is combined with Ondansetron.
Hydroxychloroquine Hydroxychloroquine The metabolism of Ondansetron can be decreased when combined with Hydroxychloroquine.
Meloxicam Meloxicam The metabolism of Ondansetron can be decreased when combined with Meloxicam.
Oxcarbazepine Oxcarbazepine The metabolism of Ondansetron can be increased when combined with Oxcarbazepine.
Zaleplon Zaleplon The risk or severity of adverse effects can be increased when Ondansetron is combined with Zaleplon.
Anakinra Anakinra The metabolism of Ondansetron can be increased when combined with Anakinra.
Desloratadine Desloratadine The risk or severity of adverse effects can be increased when Ondansetron is combined with Desloratadine.
Linezolid Linezolid The risk or severity of serotonin syndrome can be increased when Linezolid is combined with Ondansetron.
Trimipramine Trimipramine The metabolism of Ondansetron can be decreased when combined with Trimipramine.
Etanercept Injection Etanercept Injection The metabolism of Ondansetron can be increased when combined with Etanercept.
Glycopyrrolate Glycopyrrolate Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
Modafinil Modafinil The metabolism of Ondansetron can be increased when combined with Modafinil.
Sirolimus Sirolimus The metabolism of Sirolimus can be decreased when combined with Ondansetron.
Dutasteride Dutasteride The metabolism of Dutasteride can be decreased when combined with Ondansetron.
Epinephrine Injection Epinephrine Injection The metabolism of Ondansetron can be decreased when combined with Epinephrine.
Eplerenone Eplerenone The metabolism of Ondansetron can be decreased when combined with Eplerenone.
Escitalopram Escitalopram The risk or severity of serotonin syndrome can be increased when Ondansetron is combined with Escitalopram.
Zonisamide Zonisamide The risk or severity of adverse effects can be increased when Ondansetron is combined with Zonisamide.
Adalimumab Injection Adalimumab Injection The metabolism of Ondansetron can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The risk or severity of adverse effects can be increased when Ondansetron is combined with Aripiprazole.
Atomoxetine Atomoxetine The risk or severity of adverse effects can be increased when Atomoxetine is combined with Ondansetron.
Dexmethylphenidate Dexmethylphenidate The risk or severity of adverse effects can be increased when Ondansetron is combined with Dexmethylphenidate.
Atazanavir Atazanavir The metabolism of Ondansetron can be decreased when combined with Atazanavir.
Almotriptan Almotriptan The risk or severity of adverse effects can be increased when Ondansetron is combined with Almotriptan.
Eletriptan Eletriptan The risk or severity of adverse effects can be increased when Eletriptan is combined with Ondansetron.
Mefloquine Mefloquine The risk or severity of QTc prolongation can be increased when Mefloquine is combined with Ondansetron.
Rosuvastatin Rosuvastatin The metabolism of Rosuvastatin can be decreased when combined with Ondansetron.
Vardenafil Vardenafil The risk or severity of QTc prolongation can be increased when Vardenafil is combined with Ondansetron.
Alfuzosin Alfuzosin The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Ondansetron.
Aprepitant Aprepitant The metabolism of Ondansetron can be decreased when combined with Aprepitant.
Tegaserod Tegaserod The metabolism of Tegaserod can be decreased when combined with Ondansetron.
Tadalafil Tadalafil The metabolism of Ondansetron can be decreased when combined with Tadalafil.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be decreased when combined with Ondansetron.
Gemifloxacin Gemifloxacin The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Gemifloxacin.
Progesterone Progesterone The metabolism of Ondansetron can be decreased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The risk or severity of adverse effects can be increased when Ondansetron is combined with Apomorphine.
Infliximab Injection Infliximab Injection The metabolism of Ondansetron can be increased when combined with Infliximab.
Oxandrolone Oxandrolone The metabolism of Ondansetron can be decreased when combined with Oxandrolone.
Protriptyline Protriptyline The risk or severity of adverse effects can be increased when Protriptyline is combined with Ondansetron.
Duloxetine Duloxetine The metabolism of Ondansetron can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Ondansetron can be decreased when combined with Norethisterone.
Trospium Trospium Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Trospium.
Bosentan Bosentan The metabolism of Ondansetron can be increased when combined with Bosentan.
Cinacalcet Cinacalcet The metabolism of Ondansetron can be decreased when combined with Cinacalcet.
Erlotinib Erlotinib The metabolism of Erlotinib can be decreased when combined with Ondansetron.
Eszopiclone Eszopiclone The risk or severity of CNS depression can be increased when Ondansetron is combined with Eszopiclone.
Solifenacin Solifenacin The risk or severity of QTc prolongation can be increased when Solifenacin is combined with Ondansetron.
Voriconazole Voriconazole The metabolism of Ondansetron can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine The risk or severity of adverse effects can be increased when Amphetamine is combined with Ondansetron.
Entecavir Entecavir The metabolism of Entecavir can be decreased when combined with Ondansetron.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Ondansetron can be increased when combined with Peginterferon alfa-2b.
Sodium Oxybate Sodium Oxybate Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Ondansetron.
Ibandronate Ibandronate The risk or severity of QTc prolongation can be increased when Ibandronate is combined with Ondansetron.
Isocarboxazid Isocarboxazid The risk or severity of adverse effects can be increased when Ondansetron is combined with Isocarboxazid.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Ondansetron.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Ondansetron.
Fentanyl Fentanyl The risk or severity of adverse effects can be increased when Fentanyl is combined with Ondansetron.
Pregabalin Pregabalin The therapeutic efficacy of Ondansetron can be increased when used in combination with Pregabalin.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Ondansetron.
Felbamate Felbamate The risk or severity of QTc prolongation can be increased when Felbamate is combined with Ondansetron.
Ranolazine Ranolazine The serum concentration of Ondansetron can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Ondansetron can be increased when combined with Abatacept.
Rasagiline Rasagiline The metabolism of Rasagiline can be decreased when combined with Ondansetron.
Imatinib Imatinib The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Imatinib.
Gefitinib Gefitinib The metabolism of Ondansetron can be decreased when combined with Gefitinib.
Albuterol Albuterol The risk or severity of QTc prolongation can be increased when Salbutamol is combined with Ondansetron.
Paliperidone Paliperidone The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Paliperidone.
Bortezomib Bortezomib The risk or severity of QTc prolongation can be increased when Bortezomib is combined with Ondansetron.
Oxaliplatin Injection Oxaliplatin Injection The risk or severity of QTc prolongation can be increased when Oxaliplatin is combined with Ondansetron.
Posaconazole Posaconazole The risk or severity of QTc prolongation can be increased when Posaconazole is combined with Ondansetron.
Primaquine Primaquine The metabolism of Ondansetron can be decreased when combined with Primaquine.
Pemetrexed Injection Pemetrexed Injection The metabolism of Pemetrexed can be decreased when combined with Ondansetron.
Dimenhydrinate Dimenhydrinate The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Dimenhydrinate.
Lisdexamfetamine Lisdexamfetamine The risk or severity of serotonin syndrome can be increased when Ondansetron is combined with Lisdexamfetamine.
Nabilone Nabilone Nabilone may increase the central nervous system depressant (CNS depressant) activities of Ondansetron.
Vorinostat Vorinostat The risk or severity of QTc prolongation can be increased when Vorinostat is combined with Ondansetron.
Sorafenib Sorafenib The metabolism of Ondansetron can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The risk or severity of QTc prolongation and torsade de pointes can be increased when Sunitinib is combined with Ondansetron.
Dronabinol Dronabinol Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Ondansetron.
Lapatinib Lapatinib The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Lapatinib.
Levocetirizine Levocetirizine The risk or severity of QTc prolongation can be increased when Levocetirizine is combined with Ondansetron.
Dasatinib Dasatinib The metabolism of Dasatinib can be decreased when combined with Ondansetron.
Mexiletine Mexiletine The metabolism of Mexiletine can be decreased when combined with Ondansetron.
Armodafinil Armodafinil The metabolism of Ondansetron can be increased when combined with Armodafinil.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be decreased when combined with Ondansetron.
Nilotinib Nilotinib The metabolism of Nilotinib can be decreased when combined with Ondansetron.
Toremifene Toremifene The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Toremifene.
Bexarotene Bexarotene The metabolism of Ondansetron can be decreased when combined with Bexarotene.
Budesonide Budesonide The metabolism of Ondansetron can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Ondansetron can be decreased when combined with Chloramphenicol.
OnabotulinumtoxinA Injection OnabotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Ondansetron.
RimabotulinumtoxinB Injection RimabotulinumtoxinB Injection The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Ondansetron.
Etravirine Etravirine The metabolism of Ondansetron can be decreased when combined with Etravirine.
Arsenic Trioxide Injection Arsenic Trioxide Injection The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Arsenic trioxide.
Desvenlafaxine Desvenlafaxine The risk or severity of adverse effects can be increased when Ondansetron is combined with Desvenlafaxine.
Cevimeline Cevimeline The metabolism of Ondansetron can be decreased when combined with Cevimeline.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Ondansetron.
Tretinoin Tretinoin The metabolism of Ondansetron can be decreased when combined with Tretinoin.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Ondansetron.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Ondansetron.
Certolizumab Injection Certolizumab Injection The metabolism of Ondansetron can be increased when combined with Certolizumab pegol.
Irinotecan Injection Irinotecan Injection The metabolism of Ondansetron can be decreased when combined with Irinotecan.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Ondansetron.
Rufinamide Rufinamide The risk or severity of adverse effects can be increased when Rufinamide is combined with Ondansetron.
Midazolam Midazolam The risk or severity of adverse effects can be increased when Midazolam is combined with Ondansetron.
Naltrexone Injection Naltrexone Injection The risk or severity of serotonin syndrome can be increased when Naltrexone is combined with Ondansetron.
Eltrombopag Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Ondansetron.
Milnacipran Milnacipran The risk or severity of adverse effects can be increased when Ondansetron is combined with Milnacipran.
Fesoterodine Fesoterodine Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
Degarelix Injection Degarelix Injection The risk or severity of QTc prolongation can be increased when Degarelix is combined with Ondansetron.
Betaxolol Betaxolol The risk or severity of QTc prolongation can be increased when Betaxolol is combined with Ondansetron.
Iloperidone Iloperidone The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Iloperidone.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Ondansetron.
Lacosamide Lacosamide The risk or severity of adverse effects can be increased when Ondansetron is combined with Lacosamide.
Everolimus Everolimus The metabolism of Everolimus can be decreased when combined with Ondansetron.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Ondansetron.
AbobotulinumtoxinA Injection AbobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Ondansetron.
Palonosetron Injection Palonosetron Injection The risk or severity of adverse effects can be increased when Palonosetron is combined with Ondansetron.
Saxagliptin Saxagliptin The metabolism of Saxagliptin can be decreased when combined with Ondansetron.
Telavancin Injection Telavancin Injection The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Telavancin.
Romidepsin Injection Romidepsin Injection The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Romidepsin.
Tapentadol Tapentadol Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Ondansetron.
Golimumab Injection Golimumab Injection The metabolism of Ondansetron can be increased when combined with Golimumab.
Pazopanib Pazopanib The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Pazopanib.
Asenapine Asenapine The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Asenapine.
Vigabatrin Vigabatrin The risk or severity of adverse effects can be increased when Ondansetron is combined with Vigabatrin.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Ondansetron.
Albendazole Albendazole The metabolism of Albendazole can be decreased when combined with Ondansetron.
Levonorgestrel Levonorgestrel The metabolism of Ondansetron can be decreased when combined with Levonorgestrel.
Oxymorphone Oxymorphone The risk or severity of adverse effects can be increased when Ondansetron is combined with Oxymorphone.
Tocilizumab Injection Tocilizumab Injection The metabolism of Ondansetron can be increased when combined with Tocilizumab.
Eribulin Injection Eribulin Injection The risk or severity of QTc prolongation can be increased when Eribulin is combined with Ondansetron.
IncobotulinumtoxinA Injection IncobotulinumtoxinA Injection The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Ondansetron.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Ondansetron.
Lurasidone Lurasidone The risk or severity of adverse effects can be increased when Ondansetron is combined with Lurasidone.
Acetaminophen Injection Acetaminophen Injection The metabolism of Acetaminophen can be decreased when combined with Ondansetron.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Ondansetron.
Terbutaline Injection Terbutaline Injection The risk or severity of QTc prolongation can be increased when Terbutaline is combined with Ondansetron.
Rilpivirine Rilpivirine The metabolism of Rilpivirine can be decreased when combined with Ondansetron.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Ondansetron can be decreased when combined with Cyclophosphamide.
Abiraterone Abiraterone The metabolism of Ondansetron can be decreased when combined with Abiraterone.
Triptorelin Injection Triptorelin Injection The risk or severity of QTc prolongation can be increased when Triptorelin is combined with Ondansetron.
Rivaroxaban Rivaroxaban The metabolism of Rivaroxaban can be decreased when combined with Ondansetron.
Ticagrelor Ticagrelor The metabolism of Ondansetron can be decreased when combined with Ticagrelor.
Vandetanib Vandetanib The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Vandetanib.
Clobazam Clobazam The metabolism of Ondansetron can be decreased when combined with Clobazam.
Vemurafenib Vemurafenib The risk or severity of QTc prolongation can be increased when Vemurafenib is combined with Ondansetron.
Vismodegib Vismodegib The metabolism of Ondansetron can be decreased when combined with Vismodegib.
Ivacaftor Ivacaftor The metabolism of Ivacaftor can be decreased when combined with Ondansetron.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Ondansetron.
Crizotinib Crizotinib The metabolism of Ondansetron can be decreased when combined with Crizotinib.
Cabergoline Cabergoline The risk or severity of adverse effects can be increased when Cabergoline is combined with Ondansetron.
Ambrisentan Ambrisentan The metabolism of Ambrisentan can be decreased when combined with Ondansetron.
Ezogabine Ezogabine The risk or severity of adverse effects can be increased when Ondansetron is combined with Tiagabine.
Enzalutamide Enzalutamide The metabolism of Ondansetron can be increased when combined with Enzalutamide.
Mirabegron Mirabegron The metabolism of Ondansetron can be decreased when combined with Mirabegron.
Regorafenib Regorafenib The metabolism of Ondansetron can be decreased when combined with Regorafenib.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Ondansetron.
Bedaquiline Bedaquiline The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Bedaquiline.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Ondansetron.
Ponatinib Ponatinib The metabolism of Ponatinib can be decreased when combined with Ondansetron.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Ondansetron.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be decreased when combined with Ondansetron.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Ondansetron.
Dabrafenib Dabrafenib The metabolism of Ondansetron can be increased when combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Ondansetron.
Levomilnacipran Levomilnacipran The risk or severity of adverse effects can be increased when Ondansetron is combined with Levomilnacipran.
Vortioxetine Vortioxetine The risk or severity of adverse effects can be increased when Ondansetron is combined with Vortioxetine.
Perampanel Perampanel Perampanel may increase the central nervous system depressant (CNS depressant) activities of Ondansetron.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Ondansetron.
Ketorolac Injection Ketorolac Injection The metabolism of Ondansetron can be decreased when combined with Ketorolac.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Ondansetron.
Apremilast Apremilast The metabolism of Ondansetron can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Ondansetron can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Ondansetron can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The risk or severity of adverse effects can be increased when Ondansetron is combined with Eslicarbazepine.
Testosterone Injection Testosterone Injection The metabolism of Ondansetron can be decreased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Ondansetron can be decreased when combined with Oritavancin.
Hydrocodone Hydrocodone Hydrocodone may increase the central nervous system depressant (CNS depressant) activities of Ondansetron.
Suvorexant Suvorexant Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
Olaparib Olaparib The metabolism of Olaparib can be decreased when combined with Ondansetron.
Methamphetamine Methamphetamine The risk or severity of adverse effects can be increased when Ondansetron is combined with Metamfetamine.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be decreased when combined with Ondansetron.
Pirfenidone Pirfenidone The metabolism of Pirfenidone can be decreased when combined with Ondansetron.
Secukinumab Injection Secukinumab Injection The metabolism of Ondansetron can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The risk or severity of adverse effects can be increased when Risperidone is combined with Ondansetron.
Lenvatinib Lenvatinib The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Ondansetron can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Panobinostat can be decreased when combined with Ondansetron.
Haloperidol Injection Haloperidol Injection The risk or severity of QTc prolongation can be increased when Haloperidol is combined with Ondansetron.
Ivabradine Ivabradine Ivabradine may increase the QTc-prolonging activities of Ondansetron.
Flibanserin Flibanserin The risk or severity of adverse effects can be increased when Ondansetron is combined with Flibanserin.
Rolapitant Rolapitant The metabolism of Ondansetron can be decreased when combined with Rolapitant.
Daclatasvir Daclatasvir The metabolism of Daclatasvir can be decreased when combined with Ondansetron.
Brexpiprazole Brexpiprazole The risk or severity of adverse effects can be increased when Ondansetron is combined with Brexpiprazole.
Ziprasidone Injection Ziprasidone Injection The risk or severity of QTc prolongation can be increased when Ziprasidone is combined with Ondansetron.
Cariprazine Cariprazine The risk or severity of adverse effects can be increased when Ondansetron is combined with Cariprazine.
Eluxadoline Eluxadoline The risk or severity of serotonin syndrome can be increased when Ondansetron is combined with Eluxadoline.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Ondansetron.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Ondansetron.
Dexamethasone Injection Dexamethasone Injection The metabolism of Ondansetron can be increased when combined with Dexamethasone.
Brivaracetam Injection Brivaracetam Injection The risk or severity of adverse effects can be increased when Ondansetron is combined with Brivaracetam.
Cobicistat Cobicistat The metabolism of Ondansetron can be decreased when combined with Cobicistat.
Pimavanserin Pimavanserin The risk or severity of adverse effects can be increased when Ondansetron is combined with Pimavanserin.
Diphenhydramine Injection Diphenhydramine Injection The risk or severity of adverse effects can be increased when Ondansetron is combined with Diphenhydramine.
Rucaparib Rucaparib The metabolism of Ondansetron can be decreased when combined with Rucaparib.
Ribociclib Ribociclib The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Ribociclib.
Doxepin (Insomnia) Doxepin (Insomnia) Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Doxepin.
Deutetrabenazine Deutetrabenazine The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Deutetrabenazine.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Ondansetron.
Deflazacort Deflazacort The metabolism of Ondansetron can be increased when combined with Deflazacort.
Safinamide Safinamide The metabolism of Ondansetron can be decreased when combined with Safinamide.
Midostaurin Midostaurin The metabolism of Ondansetron can be decreased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Ondansetron can be decreased when combined with Enasidenib.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be decreased when combined with Ondansetron.
Delafloxacin Delafloxacin The risk or severity of QTc prolongation can be increased when Delafloxacin is combined with Ondansetron.
Acalabrutinib Acalabrutinib The metabolism of Ondansetron can be decreased when combined with Acalabrutinib.
Letermovir Letermovir The metabolism of Ondansetron can be decreased when combined with Letermovir.
Tetrabenazine Tetrabenazine The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Tetrabenazine.
Buprenorphine Injection Buprenorphine Injection Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
Apalutamide Apalutamide The metabolism of Ondansetron can be increased when combined with Apalutamide.
Avatrombopag Avatrombopag The metabolism of Ondansetron can be increased when combined with Avatrombopag.
Lofexidine Lofexidine The therapeutic efficacy of Ondansetron can be increased when used in combination with Lofexidine.
Eliglustat Eliglustat The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Eliglustat.
Encorafenib Encorafenib The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Encorafenib.
Binimetinib Binimetinib The metabolism of Binimetinib can be decreased when combined with Ondansetron.
Ivosidenib Ivosidenib The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Ivosidenib.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Ondansetron.
Doravirine Doravirine The metabolism of Doravirine can be decreased when combined with Ondansetron.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Ondansetron.
Cannabidiol Cannabidiol The risk or severity of adverse effects can be increased when Cannabidiol is combined with Ondansetron.
Dacomitinib Dacomitinib The metabolism of Ondansetron can be decreased when combined with Dacomitinib.
Stiripentol Stiripentol The metabolism of Ondansetron can be decreased when combined with Stiripentol.
Gilteritinib Gilteritinib The therapeutic efficacy of Ondansetron can be decreased when used in combination with Gilteritinib.
Glasdegib Glasdegib The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Glasdegib.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Ondansetron.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Ondansetron.
Rifamycin Rifamycin The metabolism of Ondansetron can be decreased when combined with Rifamycin.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Ondansetron can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be decreased when combined with Ondansetron.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Ondansetron.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be decreased when combined with Ondansetron.
Alpelisib Alpelisib The serum concentration of Ondansetron can be decreased when it is combined with Alpelisib.
Brexanolone Injection Brexanolone Injection The risk or severity of adverse effects can be increased when Ondansetron is combined with Brexanolone.
Solriamfetol Solriamfetol The risk or severity of adverse effects can be increased when Ondansetron is combined with Solriamfetol.
Triclabendazole Triclabendazole The risk or severity of QTc prolongation can be increased when Triclabendazole is combined with Ondansetron.
Entrectinib Entrectinib The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Entrectinib.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Ondansetron.
Pitolisant Pitolisant The serum concentration of Ondansetron can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Ondansetron can be decreased when combined with Fedratinib.
Lefamulin Lefamulin Lefamulin may increase the QTc-prolonging activities of Ondansetron.
Phenytoin Injection Phenytoin Injection The metabolism of Ondansetron can be decreased when combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Ondansetron.
Voxelotor Voxelotor The metabolism of Voxelotor can be decreased when combined with Ondansetron.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Ondansetron.
Lumateperone Lumateperone The risk or severity of adverse effects can be increased when Ondansetron is combined with Lumateperone.
Lasmiditan Lasmiditan The risk or severity of serotonin syndrome can be increased when Ondansetron is combined with Lasmiditan.
Cenobamate Cenobamate The serum concentration of Ondansetron can be decreased when it is combined with Cenobamate.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Ondansetron.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Ondansetron.
Lemborexant Lemborexant The risk or severity of adverse effects can be increased when Ondansetron is combined with Lemborexant.
Fenfluramine Fenfluramine The risk or severity of serotonin syndrome can be increased when Fenfluramine is combined with Ondansetron.
Fostemsavir Fostemsavir The risk or severity of QTc prolongation can be increased when Fostemsavir is combined with Ondansetron.
Octreotide Octreotide The risk or severity of QTc prolongation can be increased when Octreotide is combined with Ondansetron.
Pralsetinib Pralsetinib The metabolism of Ondansetron can be decreased when combined with Pralsetinib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Ondansetron can be decreased when it is combined with Satralizumab.
Relugolix Relugolix The risk or severity of QTc prolongation can be increased when Relugolix is combined with Ondansetron.
Viloxazine Viloxazine The risk or severity of adverse effects can be increased when Ondansetron is combined with Viloxazine.
Theophylline Theophylline The metabolism of Theophylline can be decreased when combined with Ondansetron.
Indomethacin Indomethacin The metabolism of Ondansetron can be decreased when combined with Indomethacin.
Mefenamic Acid Mefenamic Acid The metabolism of Ondansetron can be decreased when combined with Mefenamic acid.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Ondansetron.
Trazodone Trazodone The risk or severity of QTc prolongation can be increased when Trazodone is combined with Ondansetron.
Hydroxyurea Hydroxyurea The metabolism of Ondansetron can be decreased when combined with Hydroxyurea.
Floxuridine Floxuridine The metabolism of Ondansetron can be decreased when combined with Floxuridine.
Phenobarbital Phenobarbital The metabolism of Ondansetron can be decreased when combined with Phenobarbital.
Metaxalone Metaxalone The risk or severity of adverse effects can be increased when Metaxalone is combined with Ondansetron.
Levorphanol Levorphanol The risk or severity of adverse effects can be increased when Levorphanol is combined with Ondansetron.
Primidone Primidone The risk or severity of adverse effects can be increased when Primidone is combined with Ondansetron.
Methsuximide Methsuximide The risk or severity of QTc prolongation can be increased when Methsuximide is combined with Ondansetron.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Ondansetron is combined with Diethylpropion.
Chlorpromazine Chlorpromazine The metabolism of Ondansetron can be decreased when combined with Chlorpromazine.
Diazepam Diazepam The risk or severity of adverse effects can be increased when Diazepam is combined with Ondansetron.
Oxazepam Oxazepam The risk or severity of adverse effects can be increased when Oxazepam is combined with Ondansetron.
Flurazepam Flurazepam The risk or severity of adverse effects can be increased when Flurazepam is combined with Ondansetron.
Clorazepate Clorazepate The risk or severity of adverse effects can be increased when Clorazepic acid is combined with Ondansetron.
Lorazepam Lorazepam The risk or severity of adverse effects can be increased when Lorazepam is combined with Ondansetron.
Carmustine Carmustine The metabolism of Carmustine can be decreased when combined with Ondansetron.
Amantadine Amantadine The risk or severity of serotonin syndrome can be increased when Ondansetron is combined with Amantadine.
Codeine Codeine The risk or severity of adverse effects can be increased when Codeine is combined with Ondansetron.
Meprobamate Meprobamate The risk or severity of adverse effects can be increased when Meprobamate is combined with Ondansetron.
Chlordiazepoxide Chlordiazepoxide The risk or severity of adverse effects can be increased when Chlordiazepoxide is combined with Ondansetron.
Bromocriptine Bromocriptine The risk or severity of adverse effects can be increased when Ondansetron is combined with Bromocriptine.
Tranylcypromine Tranylcypromine The metabolism of Ondansetron can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The risk or severity of adverse effects can be increased when Phenelzine is combined with Ondansetron.
Procarbazine Procarbazine The risk or severity of adverse effects can be increased when Ondansetron is combined with Procarbazine.
Ergoloid Mesylates Ergoloid Mesylates The risk or severity of adverse effects can be increased when Ondansetron is combined with Ergoloid mesylate.
Minocycline Minocycline Minocycline may increase the central nervous system depressant (CNS depressant) activities of Ondansetron.
Prochlorperazine Prochlorperazine The risk or severity of adverse effects can be increased when Prochlorperazine is combined with Ondansetron.
Thioridazine Thioridazine The risk or severity of QTc prolongation can be increased when Thioridazine is combined with Ondansetron.
Trifluoperazine Trifluoperazine The risk or severity of adverse effects can be increased when Trifluoperazine is combined with Ondansetron.
Dapsone Dapsone The metabolism of Ondansetron can be decreased when combined with Dapsone.
Sulfadiazine Sulfadiazine The metabolism of Ondansetron can be decreased when combined with Sulfadiazine.
Oxycodone Oxycodone The risk or severity of adverse effects can be increased when Oxycodone is combined with Ondansetron.
Methadone Methadone The risk or severity of adverse effects can be increased when Methadone is combined with Ondansetron.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Ondansetron.
Benztropine Benztropine The risk or severity of QTc prolongation can be increased when Benzatropine is combined with Ondansetron.
Maprotiline Maprotiline The risk or severity of adverse effects can be increased when Ondansetron is combined with Maprotiline.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Ondansetron.
Trihexyphenidyl Trihexyphenidyl Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
Orphenadrine Orphenadrine Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
Perphenazine Perphenazine The risk or severity of adverse effects can be increased when Perphenazine is combined with Ondansetron.
Azathioprine Azathioprine The metabolism of Azathioprine can be decreased when combined with Ondansetron.
Fluphenazine Fluphenazine The risk or severity of adverse effects can be increased when Fluphenazine is combined with Ondansetron.
Phentermine Phentermine The risk or severity of serotonin syndrome can be increased when Phentermine is combined with Ondansetron.
Amoxapine Amoxapine The metabolism of Amoxapine can be decreased when combined with Ondansetron.
Hydrocortisone Hydrocortisone The metabolism of Ondansetron can be decreased when combined with Hydrocortisone.
Doxorubicin Doxorubicin The metabolism of Ondansetron can be decreased when combined with Doxorubicin.
Carbamazepine Carbamazepine The metabolism of Ondansetron can be decreased when combined with Carbamazepine.
Molindone Molindone The risk or severity of adverse effects can be increased when Ondansetron is combined with Molindone.
Clonidine Clonidine The risk or severity of sedation can be increased when Clonidine is combined with Ondansetron.
Cimetidine Cimetidine The metabolism of Ondansetron can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Warfarin can be decreased when combined with Ondansetron.
Clonazepam Clonazepam The risk or severity of adverse effects can be increased when Ondansetron is combined with Clonazepam.
Loperamide Loperamide The risk or severity of QTc prolongation can be increased when Loperamide is combined with Ondansetron.
Promethazine Promethazine The metabolism of Ondansetron can be decreased when combined with Promethazine.
Daunorubicin Daunorubicin The metabolism of Ondansetron can be increased when combined with Daunorubicin.
Digoxin Digoxin The risk or severity of QTc prolongation can be increased when Digoxin is combined with Ondansetron.
Loxapine Loxapine The risk or severity of adverse effects can be increased when Loxapine is combined with Ondansetron.
Chloroquine Chloroquine The metabolism of Ondansetron can be decreased when combined with Chloroquine.
Quinine Quinine The metabolism of Quinine can be decreased when combined with Ondansetron.
Ethosuximide Ethosuximide The risk or severity of QTc prolongation can be increased when Ethosuximide is combined with Ondansetron.
Triamterene Triamterene The metabolism of Triamterene can be decreased when combined with Ondansetron.
Sulfinpyrazone Sulfinpyrazone The metabolism of Ondansetron can be decreased when combined with Sulfinpyrazone.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Ondansetron.
Secobarbital Secobarbital The risk or severity of adverse effects can be increased when Secobarbital is combined with Ondansetron.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Ondansetron.
Amitriptyline Amitriptyline The metabolism of Ondansetron can be decreased when combined with Amitriptyline.
Imipramine Imipramine The metabolism of Ondansetron can be decreased when combined with Imipramine.
Probenecid Probenecid The metabolism of Ondansetron can be decreased when combined with Probenecid.
Quinidine Quinidine The metabolism of Quinidine can be decreased when combined with Ondansetron.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Ondansetron.
Isoniazid Isoniazid The metabolism of Ondansetron can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Ondansetron can be increased when combined with Rifampicin.
Disopyramide Disopyramide The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Disopyramide.
Valproic Acid Valproic Acid The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Ondansetron can be decreased when combined with Tamoxifen.
Butabarbital Butabarbital The risk or severity of adverse effects can be increased when Butabarbital is combined with Ondansetron.
Methimazole Methimazole The metabolism of Ondansetron can be decreased when combined with Methimazole.
Chlorpropamide Chlorpropamide The metabolism of Ondansetron can be decreased when combined with Chlorpropamide.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Ondansetron.
Tolazamide Tolazamide The metabolism of Ondansetron can be decreased when combined with Tolazamide.
Dextromethorphan Dextromethorphan The risk or severity of adverse effects can be increased when Dextromethorphan is combined with Ondansetron.
Cyclobenzaprine Cyclobenzaprine The risk or severity of CNS depression can be increased when Ondansetron is combined with Cyclobenzaprine.
Niacin Niacin The metabolism of Ondansetron can be decreased when combined with Niacin.
Baclofen Baclofen The risk or severity of adverse effects can be increased when Baclofen is combined with Ondansetron.
Doxylamine Doxylamine Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Ondansetron.
Cyproheptadine Cyproheptadine The risk or severity of QTc prolongation can be increased when Cyproheptadine is combined with Ondansetron.
Clemastine Clemastine The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Clemastine.
Chlorpheniramine Chlorpheniramine The risk or severity of adverse effects can be increased when Ondansetron is combined with Chlorpheniramine.
Brompheniramine Brompheniramine The risk or severity of QTc prolongation can be increased when Dexbrompheniramine is combined with Ondansetron.
Meclizine Meclizine The risk or severity of adverse effects can be increased when Meclizine is combined with Ondansetron.
Hydrochlorothiazide Hydrochlorothiazide The risk or severity of QTc prolongation can be increased when Hydrochlorothiazide is combined with Ondansetron.
Dantrolene Dantrolene The risk or severity of adverse effects can be increased when Ondansetron is combined with Dantrolene.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Ondansetron.
Carisoprodol Carisoprodol The risk or severity of adverse effects can be increased when Carisoprodol is combined with Ondansetron.
Methocarbamol Methocarbamol The risk or severity of adverse effects can be increased when Methocarbamol is combined with Ondansetron.
Disulfiram Disulfiram The risk or severity of QTc prolongation can be increased when Disulfiram is combined with Ondansetron.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The risk or severity of QTc prolongation can be increased when Propranolol is combined with Ondansetron.
Pseudoephedrine Pseudoephedrine The risk or severity of serotonin syndrome can be increased when Pseudoephedrine is combined with Ondansetron.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Ondansetron.
Nadolol Nadolol The metabolism of Nadolol can be decreased when combined with Ondansetron.
Butorphanol Injection Butorphanol Injection The risk or severity of adverse effects can be increased when Butorphanol is combined with Ondansetron.
Nalbuphine Injection Nalbuphine Injection The risk or severity of adverse effects can be increased when Nalbuphine is combined with Ondansetron.
Oxytocin Injection Oxytocin Injection The risk or severity of QTc prolongation can be increased when Oxytocin is combined with Ondansetron.
Trimethobenzamide Trimethobenzamide The risk or severity of adverse effects can be increased when Trimethobenzamide is combined with Ondansetron.
Flavoxate Flavoxate Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
Papaverine Papaverine The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Papaverine.
Fluorouracil Injection Fluorouracil Injection The metabolism of Ondansetron can be decreased when combined with Fluorouracil.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Ondansetron.
Acetazolamide Acetazolamide The risk or severity of adverse effects can be increased when Acetazolamide is combined with Ondansetron.
Ketoconazole Ketoconazole The metabolism of Ondansetron can be decreased when combined with Ketoconazole.
Pyrantel Pyrantel The risk or severity of adverse effects can be increased when Ondansetron is combined with Pyrantel.
Vincristine Injection Vincristine Injection The metabolism of Ondansetron can be decreased when combined with Vincristine.
Vinblastine Vinblastine The metabolism of Ondansetron can be decreased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Ondansetron can be decreased when combined with Metoprolol.
Hydroxyzine Hydroxyzine The risk or severity of QTc prolongation can be increased when Hydroxyzine is combined with Ondansetron.
Thiothixene Thiothixene The risk or severity of adverse effects can be increased when Ondansetron is combined with Thiothixene.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Ondansetron.
Alprazolam Alprazolam The risk or severity of adverse effects can be increased when Alprazolam is combined with Ondansetron.
Temazepam Temazepam The risk or severity of adverse effects can be increased when Temazepam is combined with Ondansetron.
Triazolam Triazolam The risk or severity of adverse effects can be increased when Triazolam is combined with Ondansetron.
Dicyclomine Dicyclomine Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
Hyoscyamine Hyoscyamine The risk or severity of QTc prolongation can be increased when Hyoscyamine is combined with Ondansetron.
Propantheline Propantheline Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
Trimethoprim Trimethoprim The metabolism of Ondansetron can be decreased when combined with Trimethoprim.
Diltiazem Diltiazem The metabolism of Ondansetron can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Nifedipine.
Timolol Timolol The risk or severity of QTc prolongation can be increased when Timolol is combined with Ondansetron.
Verapamil Verapamil The metabolism of Ondansetron can be decreased when combined with Verapamil.
Atenolol Atenolol The metabolism of Ondansetron can be decreased when combined with Atenolol.
Pindolol Pindolol The risk or severity of adverse effects can be increased when Ondansetron is combined with Pindolol.
Cisplatin Injection Cisplatin Injection The metabolism of Ondansetron can be decreased when combined with Cisplatin.
Piroxicam Piroxicam The metabolism of Ondansetron can be decreased when combined with Piroxicam.
Etoposide Etoposide The metabolism of Etoposide can be decreased when combined with Ondansetron.
Glyburide Glyburide The metabolism of Ondansetron can be decreased when combined with Glyburide.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Ondansetron.
Indapamide Indapamide The risk or severity of QTc prolongation can be increased when Indapamide is combined with Ondansetron.
Pentoxifylline Pentoxifylline The metabolism of Pentoxifylline can be decreased when combined with Ondansetron.
Pentamidine Injection Pentamidine Injection The risk or severity of QTc prolongation can be increased when Pentamidine is combined with Ondansetron.
Labetalol Labetalol The metabolism of Ondansetron can be decreased when combined with Labetalol.
Leuprolide Injection Leuprolide Injection The risk or severity of QTc prolongation can be increased when Leuprolide is combined with Ondansetron.
Gemfibrozil Gemfibrozil The metabolism of Ondansetron can be decreased when combined with Gemfibrozil.
Guanabenz Guanabenz The metabolism of Guanabenz can be decreased when combined with Ondansetron.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Ondansetron.
Flurbiprofen Flurbiprofen The metabolism of Ondansetron can be decreased when combined with Flurbiprofen.
Amiodarone Amiodarone The risk or severity of QTc prolongation can be increased when Amiodarone is combined with Ondansetron.
Buspirone Buspirone The risk or severity of serotonin syndrome can be increased when Buspirone is combined with Ondansetron.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Ondansetron.
Ciprofloxacin Ciprofloxacin The risk or severity of QTc prolongation can be increased when Ciprofloxacin is combined with Ondansetron.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Ondansetron.
Fluoxetine Fluoxetine The serum concentration of Ondansetron can be increased when it is combined with Fluoxetine.
Nimodipine Nimodipine The risk or severity of QTc prolongation can be increased when Nimodipine is combined with Ondansetron.
Clozapine Clozapine The metabolism of Ondansetron can be decreased when combined with Clozapine.
Estazolam Estazolam The risk or severity of adverse effects can be increased when Ondansetron is combined with Estazolam.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Ondansetron.
Ofloxacin Ofloxacin The risk or severity of QTc prolongation can be increased when Ondansetron is combined with Ofloxacin.
Clarithromycin Clarithromycin The metabolism of Ondansetron can be decreased when combined with Clarithromycin.
Etodolac Etodolac The metabolism of Ondansetron can be decreased when combined with Etodolac.
Felodipine Felodipine The metabolism of Felodipine can be decreased when combined with Ondansetron.
Nabumetone Nabumetone The metabolism of Nabumetone can be decreased when combined with Ondansetron.
Simvastatin Simvastatin The metabolism of Ondansetron can be decreased when combined with Simvastatin.
Teniposide Injection Teniposide Injection The metabolism of Ondansetron can be decreased when combined with Teniposide.
Itraconazole Itraconazole The metabolism of Ondansetron can be decreased when combined with Itraconazole.
Atovaquone Atovaquone The metabolism of Ondansetron can be decreased when combined with Atovaquone.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Ondansetron.
Zolpidem Zolpidem Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
Doxazosin Doxazosin The metabolism of Ondansetron can be decreased when combined with Doxazosin.
Isradipine Isradipine The risk or severity of QTc prolongation can be increased when Isradipine is combined with Ondansetron.
Omeprazole Omeprazole The metabolism of Ondansetron can be decreased when combined with Omeprazole.
Cisapride Cisapride The risk or severity of QTc prolongation can be increased when Cisapride is combined with Ondansetron.
Gabapentin Gabapentin The risk or severity of adverse effects can be increased when Ondansetron is combined with Gabapentin.
Fluvastatin Fluvastatin The metabolism of Ondansetron can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The metabolism of Ondansetron can be decreased when combined with Venlafaxine.
Fluvoxamine Fluvoxamine The metabolism of Ondansetron can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The risk or severity of adverse effects can be increased when Ondansetron is combined with Nefazodone.
Lamotrigine Lamotrigine The risk or severity of adverse effects can be increased when Lamotrigine is combined with Ondansetron.
Losartan Losartan The risk or severity of QTc prolongation can be increased when Losartan is combined with Ondansetron.
Tramadol Tramadol The risk or severity of serotonin syndrome can be increased when Tramadol is combined with Ondansetron.
Vinorelbine Injection Vinorelbine Injection The metabolism of Ondansetron can be decreased when combined with Vinorelbine.
Moexipril Moexipril The risk or severity of QTc prolongation can be increased when Moexipril is combined with Ondansetron.
Lansoprazole Lansoprazole The metabolism of Ondansetron can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Ondansetron.
Nicardipine Nicardipine The metabolism of Ondansetron can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Bupropion can be decreased when combined with Ondansetron.
Ticlopidine Ticlopidine The metabolism of Ondansetron can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The metabolism of Saquinavir can be decreased when combined with Ondansetron.
Nisoldipine Nisoldipine The metabolism of Ondansetron can be decreased when combined with Nisoldipine.
Riluzole Riluzole The metabolism of Riluzole can be decreased when combined with Ondansetron.
Glimepiride Glimepiride The metabolism of Ondansetron can be decreased when combined with Glimepiride.
Indinavir Indinavir The metabolism of Ondansetron can be decreased when combined with Indinavir.
Ritonavir Ritonavir The serum concentration of Ondansetron can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Ondansetron.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Ondansetron.
Zafirlukast Zafirlukast The metabolism of Ondansetron can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine Ondansetron may increase the serotonergic activities of Mirtazapine.
Topiramate Topiramate The risk or severity of adverse effects can be increased when Topiramate is combined with Ondansetron.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Ondansetron.
Valsartan Valsartan The metabolism of Ondansetron can be decreased when combined with Valsartan.
Pramipexole Pramipexole Ondansetron may increase the sedative activities of Pramipexole.
Donepezil Donepezil The risk or severity of adverse effects can be increased when Donepezil is combined with Ondansetron.
Nelfinavir Nelfinavir The metabolism of Ondansetron can be decreased when combined with Nelfinavir.
Azithromycin Azithromycin The risk or severity of QTc prolongation can be increased when Azithromycin is combined with Ondansetron.
Carvedilol Carvedilol The metabolism of Carvedilol can be decreased when combined with Ondansetron.
Nilutamide Nilutamide The metabolism of Ondansetron can be decreased when combined with Nilutamide.
Flutamide Flutamide The metabolism of Flutamide can be decreased when combined with Ondansetron.
Selegiline Selegiline The risk or severity of adverse effects can be increased when Ondansetron is combined with Selegiline.
Bicalutamide Bicalutamide The metabolism of Ondansetron can be decreased when combined with Bicalutamide.
Sertraline Sertraline The risk or severity of adverse effects can be increased when Ondansetron is combined with Sertraline.
Propafenone Propafenone The metabolism of Ondansetron can be decreased when combined with Propafenone.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Ondansetron.
Tamsulosin Tamsulosin The metabolism of Ondansetron can be decreased when combined with Tamsulosin.
Ropinirole Ropinirole The risk or severity of adverse effects can be increased when Ondansetron is combined with Ropinirole.
Finasteride Finasteride The metabolism of Finasteride can be decreased when combined with Ondansetron.
Quetiapine Quetiapine The risk or severity of adverse effects can be increased when Ondansetron is combined with Quetiapine.
Cetirizine Cetirizine The risk or severity of QTc prolongation can be increased when Cetirizine is combined with Ondansetron.
Paroxetine Paroxetine The metabolism of Ondansetron can be decreased when combined with Paroxetine.
Tolcapone Tolcapone The metabolism of Ondansetron can be decreased when combined with Tolcapone.
Citalopram Citalopram The risk or severity of QTc prolongation can be increased when Citalopram is combined with Ondansetron.
Capecitabine Capecitabine The metabolism of Ondansetron can be decreased when combined with Capecitabine.
Efavirenz Efavirenz The metabolism of Ondansetron can be increased when combined with Efavirenz.
Sildenafil Sildenafil The metabolism of Ondansetron can be decreased when combined with Sildenafil.
Celecoxib Celecoxib The metabolism of Ondansetron can be decreased when combined with Celecoxib.
Rosiglitazone Rosiglitazone The metabolism of Ondansetron can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine The risk or severity of QTc prolongation can be increased when Tolterodine is combined with Ondansetron.
Thalidomide Thalidomide Ondansetron may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
Nateglinide Nateglinide The metabolism of Ondansetron can be decreased when combined with Nateglinide.
Galantamine Galantamine The risk or severity of QTc prolongation can be increased when Galantamine is combined with Ondansetron.
Levetiracetam Levetiracetam The risk or severity of adverse effects can be increased when Ondansetron is combined with Levetiracetam.
Rabeprazole Rabeprazole The metabolism of Ondansetron can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Ondansetron can be decreased when combined with Terbinafine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists

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