Omeprazole

Generic name: Pronounced as (oh me' pray zol)
Brand names
  • Prilosec®
  • Prilosec® OTC
  • Talicia (as a combination product containing Amoxicillin, Omeprazole, Rifabutin)
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 04/15/2022

Prescription omeprazole is used alone or with other medications to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 1 year of age and older. Prescription omeprazole is used to treat damage from GERD in adults and children 1 month of age and older. Prescription omeprazole is used to allow the esophagus to heal and prevent further damage to the esophagus in adults and children 1 year of age and older with GERD. Prescription omeprazole is also used to treat conditions in which the stomach produces too much acid such as Zollinger-Ellison syndrome in adults. Prescription omeprazole is also used to treat ulcers (sores in the lining of the stomach or intestine) and it is also used with other medications to treat and prevent the return of ulcers caused by a certain type of bacteria (H. pylori) in adults. Nonprescription (over-the-counter) omeprazole is used to treat frequent heartburn (heartburn that occurs at least 2 or more days a week) in adults. Omeprazole is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach.

Prescription omeprazole comes as a delayed-release (releases the medication in the intestine to prevent break-down of the medication by stomach acids) capsule, and packets of delayed-release (releases the medication in the intestine to prevent break-down of the medication by stomach acids) granules for suspension (to be mixed with liquid) to take by mouth or give through a feeding tube. Nonprescription (over-the-counter) omeprazole comes as a delayed-release tablet to take by mouth. Prescription omeprazole is usually taken once a day before a meal but may be taken twice a day when used with other medications to eliminate H. pylori, or up to three times a day, before meals when used to treat conditions in which the stomach produces too much acid. The nonprescription delayed-release tablets are usually taken once a day in the morning at least 1 hour before eating for 14 days in a row. If needed, additional 14-day treatments may be repeated, not more often than once every 4 months. To help you remember to take omeprazole, take it at around the same time(s) every day. Follow the directions on your prescription label or the package label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take omeprazole exactly as directed. Do not take more or less of it or take it more often or for a longer period of time than prescribed by your doctor or stated on the package.

If you are taking the delayed-release tablets, swallow them whole with a full glass of water. Do not split, chew, or crush them or crush and mix them into food.

Swallow the delayed-release capsules whole. If you have difficulty swallowing the delayed-release capsules, place one tablespoon of soft, cool applesauce in an empty bowl. Open the delayed-release capsule and carefully empty all the granules inside the capsule onto the applesauce. Mix the granules with the applesauce and swallow the mixture immediately with a glass of cool water. Do not chew or crush the granules. Do not store the applesauce/granule mixture for future use.

If you are taking the granules for oral suspension, you will need to mix it with water before use. If you are using the 2.5-mg packet, place 1 teaspoonful (5 mL) of water in a container. If you are using the 10-mg packet, place 1 tablespoonful (15 mL) of water in a container. Add the contents of the powder packet and stir. Wait 2 to 3 minutes to allow the mixture to thicken, and stir the mixture again. Drink the entire mixture within 30 minutes. If any of the mixture is stuck to the container, pour more water into the container, stir and drink all the mixture immediately.

The granules for oral suspension can be given through a feeding tube. If you have a feeding tube, ask your doctor how you should take the medication. Follow the directions carefully.

Do not take nonprescription omeprazole for immediate relief of heartburn symptoms. It may take 1 to 4 days for you to feel the full benefit of the medication. Call your doctor if your symptoms get worse or do not improve after 14 days or if your symptoms return sooner than 4 months after you finish your treatment. Do not take nonprescription omeprazole for longer than 14 days or treat yourself with omeprazole more often than once every 4 months without talking to your doctor.

Continue to take prescription omeprazole even if you feel well. Do not stop taking prescription omeprazole without talking to your doctor. If your condition does not improve or gets worse, call your doctor.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking omeprazole,

  • tell your doctor and pharmacist if you are allergic to omeprazole, dexlansoprazole (Dexilant), esomeprazole (Nexium), lansoprazole (Prevacid), pantoprazole (Protonix), rabeprazole (Aciphex), any other medications, or any of the ingredients in the omeprazole product you will be taking. Ask your pharmacist or check the package label for a list of the ingredients.

  • tell your doctor if you are taking rilpivirine (Edurant, in Cabenuva, Complera, Odefsey). Your doctor will probably tell you not to take omeprazole if you are taking this medication.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Jantoven), atazanavir (Reyataz, in Evotaz), cilostazol, citalopram (Celexa), clopidogrel (Plavix), cyclosporine (Gengraf, Neoral, Sandimmune), dasatinib (Sprycel), diazepam (Valium, Valtoco), digoxin ( Lanoxin), disulfiram, diuretics ('water pills'), erlotinib (Tarceva), iron supplements, itraconazole (Sporanox, Tolsura), ketoconazole, methotrexate (Trexall, Xatmep), mycophenolate mofetil (Cellcept, Myfortic), nelfinavir (Viracept), nilotinib (Tasigna), phenytoin (Dilantin, Phenytek), rifampin (Rifadin, Rimactane), ritonavir (Norvir, in Kaletra), saquinavir (Invirase), tacrolimus (Astagraf, Envarsus, Prograf), and voriconazole (Vfend). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor what herbal products you are taking, especially St. John's wort. Your doctor may tell you not to take St. John's wort while taking omeprazole.

  • if you plan to take nonprescription omeprazole, tell your doctor if your heartburn has lasted 3 months or longer, if you have taken nonprescription omeprazole for a longer period of time than stated on the package, or if you have experienced any of the following symptoms: lightheadedness, sweating, or dizziness along with your heartburn; chest pain or shoulder pain; shortness of breath or wheezing; pain that spreads to your arms, neck, or shoulders; unexplained weight loss; nausea; vomiting, especially if the vomit is bloody; stomach pain; difficulty swallowing food or pain when you swallow food; or black or bloody stools. You may have a more serious condition that cannot be treated with nonprescription medication.

  • tell your doctor if you are of Asian descent and if you have or have ever had a low level of magnesium, calcium, or potassium in your blood; hypoparathyroidism (condition in which the body does not produce enough parathyroid hormone [PTH; a natural substance needed to control the amount of calcium in the blood]); low levels of vitamin B12 in your body; osteoporosis (a condition in which the bones become thin and weak and break easily); an autoimmune disease (condition in which the body attacks its own organs, causing swelling and loss of function) such as systemic lupus erythematosus; or liver disease.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Omeprazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • constipation

    • gas

    • nausea

    • diarrhea

    • vomiting

    • headache

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately, or get emergency medical help:

    • blisters, peeling, or bleeding skin; sores on the lips, nose, mouth, or genitals; swollen glands; shortness of breath; fever; or flu-like symptoms

    • rash; hives; itching; swelling of the eyes, face, lips, mouth, throat, or tongue; difficulty breathing or swallowing; or hoarseness

    • irregular, fast, or pounding heartbeat; muscle spasms; uncontrollable shaking of a part of the body; excessive tiredness; lightheadedness; dizziness; or seizures

    • severe diarrhea with watery stools, stomach pain, or fever that does not go away

    • new or worsening joint pain; rash on cheeks or arms that is sensitive to sunlight

    • increased or decreased urination, blood in urine, fatigue, nausea, loss of appetite, fever, rash, or joint pain

  • People who take proton pump inhibitors such as omeprazole may be more likely to fracture their wrists, hips, or spine than people who do not take one of these medications. People who take proton pump inhibitors may also develop fundic gland polyps (a type of growth on the stomach lining). These risks are highest in people who take high doses of one of these medications or take them for one year or longer. Talk to your doctor about the risk of taking omeprazole.

  • Omeprazole may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat, and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Symptoms of overdose may include the following:

  • confusion

  • drowsiness

  • blurred vision

  • fast or pounding heartbeat

  • nausea

  • vomiting

  • sweating

  • flushing (feeling of warmth)

  • headache

  • dry mouth

Keep all appointments with your doctor and the laboratory. Your doctor may order certain laboratory tests before and during your treatment.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking omeprazole.

Do not let anyone else take your medication. If you are taking prescription omeprazole, ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • Zegerid® (containing Omeprazole, Sodium Bicarbonate)
  • Zegerid® OTC (containing Omeprazole, Sodium Bicarbonate)

Drug Interaction
Repaglinide Repaglinide The metabolism of Repaglinide can be decreased when combined with Omeprazole.
Montelukast Montelukast The metabolism of Omeprazole can be decreased when combined with Montelukast.
Leflunomide Leflunomide Omeprazole may decrease the excretion rate of Leflunomide which could result in a higher serum level.
Delavirdine Delavirdine Delavirdine can cause a decrease in the absorption of Omeprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nevirapine Nevirapine The metabolism of Omeprazole can be decreased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Omeprazole.
Dolasetron Dolasetron The metabolism of Dolasetron can be decreased when combined with Omeprazole.
Alendronate Alendronate The therapeutic efficacy of Alendronic acid can be decreased when used in combination with Omeprazole.
Aminophylline Aminophylline The metabolism of Aminophylline can be increased when combined with Omeprazole.
Anagrelide Anagrelide The metabolism of Anagrelide can be increased when combined with Omeprazole.
Bisacodyl Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Omeprazole.
Candesartan Candesartan The metabolism of Omeprazole can be decreased when combined with Candesartan.
Cilostazol Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Omeprazole.
Clopidogrel Clopidogrel The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Omeprazole resulting in a loss in efficacy.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) Omeprazole may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be increased when combined with Omeprazole.
Mycophenolate Mycophenolate Omeprazole can cause a decrease in the absorption of Mycophenolic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Paregoric Paregoric The metabolism of Omeprazole can be decreased when combined with Morphine.
Penbutolol Penbutolol The metabolism of Acebutolol can be decreased when combined with Omeprazole.
Ranitidine Ranitidine The metabolism of Ranitidine can be increased when combined with Omeprazole.
Sumatriptan Sumatriptan Omeprazole may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus The metabolism of Tacrolimus can be decreased when combined with Omeprazole.
Tiludronate Tiludronate The therapeutic efficacy of Etidronic acid can be decreased when used in combination with Omeprazole.
Tizanidine Tizanidine The metabolism of Tizanidine can be increased when combined with Omeprazole.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Omeprazole.
Fluconazole Injection Fluconazole Injection The metabolism of Omeprazole can be decreased when combined with Fluconazole.
Hydromorphone Injection Hydromorphone Injection The metabolism of Omeprazole can be decreased when combined with Hydromorphone.
Meperidine Injection Meperidine Injection The metabolism of Meperidine can be increased when combined with Omeprazole.
Metoclopramide Injection Metoclopramide Injection The metabolism of Metoclopramide can be increased when combined with Omeprazole.
Metronidazole Injection Metronidazole Injection The metabolism of Omeprazole can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The metabolism of Omeprazole can be decreased when combined with Morphine.
Zidovudine Injection Zidovudine Injection Omeprazole may decrease the excretion rate of Zidovudine which could result in a higher serum level.
Altretamine Altretamine Omeprazole can cause an increase in the absorption of Amphetamine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Cefuroxime Cefuroxime The serum concentration of Cefuroxime can be decreased when it is combined with Omeprazole.
Cyclosporine Cyclosporine The serum concentration of Cyclosporine can be increased when it is combined with Omeprazole.
Ondansetron Ondansetron The metabolism of Ondansetron can be decreased when combined with Omeprazole.
Torsemide Torsemide The metabolism of Omeprazole can be decreased when combined with Torasemide.
Olanzapine Olanzapine The metabolism of Omeprazole can be increased when combined with Olanzapine.
Alosetron Alosetron The metabolism of Alosetron can be increased when combined with Omeprazole.
Dofetilide Dofetilide The metabolism of Dofetilide can be increased when combined with Omeprazole.
Hydroxychloroquine Hydroxychloroquine The metabolism of Hydroxychloroquine can be decreased when combined with Omeprazole.
Meloxicam Meloxicam The metabolism of Meloxicam can be decreased when combined with Omeprazole.
Oxcarbazepine Oxcarbazepine The metabolism of Omeprazole can be decreased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole The metabolism of Omeprazole can be decreased when combined with Pantoprazole.
Risedronate Risedronate Omeprazole can cause an increase in the absorption of Risedronic acid resulting in an increased serum concentration and potentially a worsening of adverse effects.
Telmisartan Telmisartan The metabolism of Omeprazole can be decreased when combined with Telmisartan.
Anakinra Anakinra The metabolism of Omeprazole can be increased when combined with Anakinra.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Omeprazole.
Etanercept Injection Etanercept Injection The metabolism of Omeprazole can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Omeprazole can be decreased when combined with Modafinil.
Tenofovir Tenofovir The metabolism of Tenofovir can be increased when combined with Omeprazole.
Sirolimus Sirolimus The metabolism of Sirolimus can be increased when combined with Omeprazole.
Epinephrine Injection Epinephrine Injection The metabolism of Omeprazole can be decreased when combined with Epinephrine.
Escitalopram Escitalopram The serum concentration of Escitalopram can be increased when it is combined with Omeprazole.
Zonisamide Zonisamide The metabolism of Zonisamide can be decreased when combined with Omeprazole.
Adalimumab Injection Adalimumab Injection The metabolism of Omeprazole can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be increased when combined with Omeprazole.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Omeprazole.
Dexmethylphenidate Dexmethylphenidate Omeprazole can cause an increase in the absorption of Dexmethylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Ezetimibe Ezetimibe Omeprazole may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Atazanavir Atazanavir Atazanavir can cause a decrease in the absorption of Omeprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Omeprazole.
Eletriptan Eletriptan The metabolism of Omeprazole can be decreased when combined with Eletriptan.
Rosuvastatin Rosuvastatin Omeprazole may decrease the excretion rate of Rosuvastatin which could result in a higher serum level.
Vardenafil Vardenafil The metabolism of Vardenafil can be decreased when combined with Omeprazole.
Alfuzosin Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Omeprazole.
Aprepitant Aprepitant The metabolism of Omeprazole can be decreased when combined with Aprepitant.
Memantine Memantine Memantine may decrease the excretion rate of Omeprazole which could result in a higher serum level.
Tegaserod Tegaserod Omeprazole may decrease the excretion rate of Tegaserod which could result in a higher serum level.
Fosamprenavir Fosamprenavir Omeprazole can cause a decrease in the absorption of Fosamprenavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be increased when combined with Omeprazole.
Progesterone Progesterone The metabolism of Omeprazole can be decreased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Omeprazole.
Infliximab Injection Infliximab Injection The metabolism of Omeprazole can be increased when combined with Infliximab.
Oxandrolone Oxandrolone The metabolism of Omeprazole can be decreased when combined with Oxandrolone.
Protriptyline Protriptyline The metabolism of Protriptyline can be decreased when combined with Omeprazole.
Rifaximin Rifaximin The metabolism of Omeprazole can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Duloxetine can be increased when combined with Omeprazole.
Norethindrone Norethindrone The metabolism of Norethisterone can be increased when combined with Omeprazole.
Bosentan Bosentan The metabolism of Omeprazole can be increased when combined with Bosentan.
Cinacalcet Cinacalcet The metabolism of Cinacalcet can be increased when combined with Omeprazole.
Erlotinib Erlotinib Omeprazole can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Eszopiclone Eszopiclone The serum concentration of Eszopiclone can be decreased when it is combined with Omeprazole.
Solifenacin Solifenacin The metabolism of Solifenacin can be decreased when combined with Omeprazole.
Voriconazole Voriconazole The metabolism of Omeprazole can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine Omeprazole can cause an increase in the absorption of Amphetamine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Entecavir Entecavir The metabolism of Entecavir can be increased when combined with Omeprazole.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Omeprazole can be increased when combined with Peginterferon alfa-2b.
Ibandronate Ibandronate The therapeutic efficacy of Ibandronate can be decreased when used in combination with Omeprazole.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Omeprazole.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Omeprazole.
Fentanyl Fentanyl The metabolism of Fentanyl can be decreased when combined with Omeprazole.
Deferasirox Deferasirox The metabolism of Omeprazole can be decreased when combined with Deferasirox.
Tipranavir Tipranavir The metabolism of Omeprazole can be increased when combined with Tipranavir.
Felbamate Felbamate The metabolism of Omeprazole can be decreased when combined with Felbamate.
Ranolazine Ranolazine The metabolism of Omeprazole can be increased when combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Omeprazole can be increased when combined with Abatacept.
Rasagiline Rasagiline The metabolism of Rasagiline can be increased when combined with Omeprazole.
Imatinib Imatinib The metabolism of Omeprazole can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Omeprazole.
Gefitinib Gefitinib Omeprazole can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Paliperidone Paliperidone The metabolism of Paliperidone can be decreased when combined with Omeprazole.
Bortezomib Bortezomib The metabolism of Omeprazole can be increased when combined with Bortezomib.
Clofarabine Injection Clofarabine Injection Omeprazole may decrease the excretion rate of Clofarabine which could result in a higher serum level.
Oxaliplatin Injection Oxaliplatin Injection Omeprazole may decrease the excretion rate of Oxaliplatin which could result in a higher serum level.
Posaconazole Posaconazole Omeprazole can cause a decrease in the absorption of Posaconazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Primaquine Primaquine The metabolism of Primaquine can be increased when combined with Omeprazole.
Darunavir Darunavir Omeprazole can cause a decrease in the absorption of Darunavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pemetrexed Injection Pemetrexed Injection The metabolism of Pemetrexed can be increased when combined with Omeprazole.
Lisdexamfetamine Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Omeprazole.
Nabilone Nabilone The metabolism of Omeprazole can be decreased when combined with Nabilone.
Retapamulin Retapamulin The metabolism of Retapamulin can be decreased when combined with Omeprazole.
Sorafenib Sorafenib The metabolism of Omeprazole can be increased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Sunitinib can be increased when combined with Omeprazole.
Dronabinol Dronabinol The metabolism of Dronabinol can be decreased when combined with Omeprazole.
Lapatinib Lapatinib The metabolism of Omeprazole can be decreased when combined with Lapatinib.
Dasatinib Dasatinib Omeprazole can cause a decrease in the absorption of Dasatinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Mexiletine Mexiletine The metabolism of Mexiletine can be increased when combined with Omeprazole.
Armodafinil Armodafinil The metabolism of Omeprazole can be decreased when combined with Armodafinil.
Ivermectin Ivermectin Omeprazole may decrease the excretion rate of Ivermectin which could result in a higher serum level.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be increased when combined with Omeprazole.
Nilotinib Nilotinib The serum concentration of Omeprazole can be decreased when it is combined with Nilotinib.
Raltegravir Raltegravir Omeprazole can cause an increase in the absorption of Raltegravir resulting in an increased serum concentration and potentially a worsening of adverse effects.
Bexarotene Bexarotene The metabolism of Omeprazole can be decreased when combined with Bexarotene.
Budesonide Budesonide Omeprazole can cause a decrease in the absorption of Budesonide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Omeprazole can be decreased when combined with Chloramphenicol.
Etravirine Etravirine The metabolism of Etravirine can be decreased when combined with Omeprazole.
Mitoxantrone Injection Mitoxantrone Injection Omeprazole may decrease the excretion rate of Mitoxantrone which could result in a higher serum level.
Cevimeline Cevimeline The metabolism of Cevimeline can be decreased when combined with Omeprazole.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Omeprazole.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Omeprazole.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be increased when combined with Omeprazole.
Flecainide Flecainide The metabolism of Omeprazole can be decreased when combined with Flecainide.
Certolizumab Injection Certolizumab Injection The metabolism of Omeprazole can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Omeprazole.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Omeprazole.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Omeprazole.
Rufinamide Rufinamide The metabolism of Rufinamide can be increased when combined with Omeprazole.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Omeprazole.
Eltrombopag Eltrombopag The metabolism of Omeprazole can be decreased when combined with Eltrombopag.
Milnacipran Milnacipran The metabolism of Milnacipran can be increased when combined with Omeprazole.
Dexlansoprazole Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Omeprazole.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Omeprazole.
Betaxolol Betaxolol The metabolism of Betaxolol can be increased when combined with Omeprazole.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Omeprazole.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Omeprazole.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Omeprazole.
Everolimus Everolimus The metabolism of Everolimus can be increased when combined with Omeprazole.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be increased when combined with Omeprazole.
Dronedarone Dronedarone The metabolism of Dronedarone can be increased when combined with Omeprazole.
Pralatrexate Injection Pralatrexate Injection Omeprazole may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Omeprazole.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be increased when combined with Omeprazole.
Tapentadol Tapentadol The metabolism of Tapentadol can be decreased when combined with Omeprazole.
Topotecan Topotecan Omeprazole may decrease the excretion rate of Topotecan which could result in a higher serum level.
Golimumab Injection Golimumab Injection The metabolism of Omeprazole can be increased when combined with Golimumab.
Pazopanib Pazopanib Omeprazole can cause a decrease in the absorption of Pazopanib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Asenapine Asenapine The metabolism of Asenapine can be increased when combined with Omeprazole.
Pitavastatin Pitavastatin Omeprazole may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole Albendazole The metabolism of Albendazole can be increased when combined with Omeprazole.
Ulipristal Ulipristal The metabolism of Ulipristal can be increased when combined with Omeprazole.
Levonorgestrel Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Omeprazole.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Omeprazole.
Tocilizumab Injection Tocilizumab Injection The metabolism of Omeprazole can be increased when combined with Tocilizumab.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be increased when combined with Omeprazole.
Acetaminophen Injection Acetaminophen Injection The metabolism of Acetaminophen can be increased when combined with Omeprazole.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Omeprazole.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be increased when combined with Omeprazole.
Roflumilast Roflumilast The metabolism of Roflumilast can be increased when combined with Omeprazole.
Linagliptin Linagliptin The metabolism of Linagliptin can be increased when combined with Omeprazole.
Rilpivirine Rilpivirine Omeprazole can cause a decrease in the absorption of Rilpivirine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Telaprevir Telaprevir Omeprazole may decrease the excretion rate of Glecaprevir which could result in a higher serum level.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Omeprazole can be increased when combined with Cyclophosphamide.
Abiraterone Abiraterone The metabolism of Omeprazole can be decreased when combined with Abiraterone.
Rivaroxaban Rivaroxaban Omeprazole may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ticagrelor Ticagrelor The metabolism of Omeprazole can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Omeprazole.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Omeprazole.
Vandetanib Vandetanib The metabolism of Vandetanib can be increased when combined with Omeprazole.
Clobazam Clobazam The metabolism of Clobazam can be decreased when combined with Omeprazole.
Vemurafenib Vemurafenib The metabolism of Vemurafenib can be increased when combined with Omeprazole.
Vismodegib Vismodegib The metabolism of Omeprazole can be decreased when combined with Vismodegib.
Axitinib Axitinib The metabolism of Axitinib can be increased when combined with Omeprazole.
Crizotinib Crizotinib The metabolism of Crizotinib can be increased when combined with Omeprazole.
Cabergoline Cabergoline The metabolism of Cabergoline can be increased when combined with Omeprazole.
Enzalutamide Enzalutamide The metabolism of Omeprazole can be increased when combined with Enzalutamide.
Mirabegron Mirabegron The metabolism of Mirabegron can be decreased when combined with Omeprazole.
Regorafenib Regorafenib The metabolism of Omeprazole can be increased when combined with Regorafenib.
Bosutinib Bosutinib Bosutinib can cause a decrease in the absorption of Omeprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Teriflunomide Teriflunomide Omeprazole may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Omeprazole.
Tofacitinib Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Omeprazole.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Omeprazole.
Ponatinib Ponatinib The metabolism of Ponatinib can be increased when combined with Omeprazole.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be increased when combined with Omeprazole.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be increased when combined with Omeprazole.
Apixaban Apixaban Omeprazole may decrease the excretion rate of Apixaban which could result in a higher serum level.
Dabrafenib Dabrafenib The serum concentration of Omeprazole can be decreased when it is combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Omeprazole.
Trametinib Trametinib The metabolism of Omeprazole can be decreased when combined with Trametinib.
Dolutegravir Dolutegravir Omeprazole may decrease the excretion rate of Dolutegravir which could result in a higher serum level.
Afatinib Afatinib Omeprazole may decrease the excretion rate of Afatinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Omeprazole.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Omeprazole.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Omeprazole.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Omeprazole.
Lomitapide Lomitapide The metabolism of Lomitapide can be increased when combined with Omeprazole.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Omeprazole.
Simeprevir Simeprevir Omeprazole may decrease the excretion rate of Simeprevir which could result in a higher serum level.
Sofosbuvir Sofosbuvir Omeprazole may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be increased when combined with Omeprazole.
Iron Sucrose Injection Iron Sucrose Injection The absorption of Iron sucrose can be decreased when combined with Omeprazole.
Apremilast Apremilast The metabolism of Omeprazole can be increased when combined with Apremilast.
Ferumoxytol Injection Ferumoxytol Injection The absorption of Ferumoxytol can be decreased when combined with Omeprazole.
Ceritinib Ceritinib The metabolism of Ceritinib can be increased when combined with Omeprazole.
Siltuximab Injection Siltuximab Injection The metabolism of Omeprazole can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The metabolism of Omeprazole can be decreased when combined with Eslicarbazepine.
Iron Dextran Injection Iron Dextran Injection The absorption of Iron Dextran can be decreased when combined with Omeprazole.
Ferric Carboxymaltose Injection Ferric Carboxymaltose Injection The absorption of Ferric carboxymaltose can be decreased when combined with Omeprazole.
Idelalisib Idelalisib The metabolism of Idelalisib can be increased when combined with Omeprazole.
Testosterone Injection Testosterone Injection Omeprazole may decrease the excretion rate of Testosterone which could result in a higher serum level.
Oritavancin Injection Oritavancin Injection The metabolism of Omeprazole can be decreased when combined with Oritavancin.
Vorapaxar Vorapaxar The metabolism of Vorapaxar can be increased when combined with Omeprazole.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Omeprazole.
Suvorexant Suvorexant The metabolism of Suvorexant can be increased when combined with Omeprazole.
Olaparib Olaparib The metabolism of Olaparib can be increased when combined with Omeprazole.
Methamphetamine Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Omeprazole.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be increased when combined with Omeprazole.
Riociguat Riociguat Omeprazole can cause a decrease in the absorption of Riociguat resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pirfenidone Pirfenidone The metabolism of Pirfenidone can be increased when combined with Omeprazole.
Nintedanib Nintedanib The metabolism of Nintedanib can be increased when combined with Omeprazole.
Secukinumab Injection Secukinumab Injection The metabolism of Omeprazole can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Risperidone can be decreased when combined with Omeprazole.
Palbociclib Palbociclib The absorption of Palbociclib can be decreased when combined with Omeprazole.
Lenvatinib Lenvatinib Omeprazole may decrease the excretion rate of Lenvatinib which could result in a higher serum level.
Naloxegol Naloxegol The metabolism of Omeprazole can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Panobinostat can be increased when combined with Omeprazole.
Haloperidol Injection Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Omeprazole.
Sonidegib Sonidegib The metabolism of Sonidegib can be increased when combined with Omeprazole.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Omeprazole.
Ziprasidone Injection Ziprasidone Injection The metabolism of Ziprasidone can be decreased when combined with Omeprazole.
Cariprazine Cariprazine The metabolism of Cariprazine can be decreased when combined with Omeprazole.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be increased when combined with Omeprazole.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Omeprazole.
Osimertinib Osimertinib The metabolism of Osimertinib can be increased when combined with Omeprazole.
Alectinib Alectinib The metabolism of Alectinib can be increased when combined with Omeprazole.
Ixazomib Ixazomib The metabolism of Ixazomib can be increased when combined with Omeprazole.
Rifapentine Rifapentine The metabolism of Omeprazole can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Omeprazole.
Dexamethasone Injection Dexamethasone Injection The metabolism of Omeprazole can be increased when combined with Dexamethasone.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Omeprazole.
Venetoclax Venetoclax The metabolism of Venetoclax can be increased when combined with Omeprazole.
Selexipag Selexipag The metabolism of Selexipag can be decreased when combined with Omeprazole.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Omeprazole.
Rucaparib Rucaparib Omeprazole may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Ribociclib Ribociclib The metabolism of Ribociclib can be increased when combined with Omeprazole.
Brigatinib Brigatinib The metabolism of Brigatinib can be increased when combined with Omeprazole.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be increased when combined with Omeprazole.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Omeprazole.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Omeprazole.
Safinamide Safinamide The metabolism of Omeprazole can be decreased when combined with Safinamide.
Midostaurin Midostaurin The metabolism of Omeprazole can be increased when combined with Midostaurin.
Neratinib Neratinib The metabolism of Neratinib can be increased when combined with Omeprazole.
Enasidenib Enasidenib The metabolism of Enasidenib can be increased when combined with Omeprazole.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Omeprazole.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Omeprazole.
Delafloxacin Delafloxacin Omeprazole may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be increased when combined with Omeprazole.
Acalabrutinib Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Omeprazole.
Letermovir Letermovir The metabolism of Omeprazole can be decreased when combined with Letermovir.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Omeprazole.
Ertugliflozin Ertugliflozin Omeprazole may decrease the excretion rate of Ertugliflozin which could result in a higher serum level.
Buprenorphine Injection Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Omeprazole.
Apalutamide Apalutamide The serum concentration of Omeprazole can be increased when it is combined with Apalutamide.
Avatrombopag Avatrombopag The metabolism of Omeprazole can be increased when combined with Avatrombopag.
Baricitinib Baricitinib The metabolism of Baricitinib can be increased when combined with Omeprazole.
Lofexidine Lofexidine The metabolism of Lofexidine can be increased when combined with Omeprazole.
Eliglustat Eliglustat The metabolism of Eliglustat can be decreased when combined with Omeprazole.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Omeprazole.
Binimetinib Binimetinib The metabolism of Binimetinib can be increased when combined with Omeprazole.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be increased when combined with Omeprazole.
Lusutrombopag Lusutrombopag Omeprazole may decrease the excretion rate of Lusutrombopag which could result in a higher serum level.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Omeprazole.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Omeprazole.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Omeprazole.
Dacomitinib Dacomitinib Omeprazole can cause a decrease in the absorption of Dacomitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Duvelisib Duvelisib Omeprazole may decrease the excretion rate of Duvelisib which could result in a higher serum level.
Stiripentol Stiripentol The metabolism of Omeprazole can be decreased when combined with Stiripentol.
Talazoparib Talazoparib Omeprazole may decrease the excretion rate of Talazoparib which could result in a higher serum level.
Gilteritinib Gilteritinib The metabolism of Gilteritinib can be increased when combined with Omeprazole.
Glasdegib Glasdegib Omeprazole may decrease the excretion rate of Glasdegib which could result in a higher serum level.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Omeprazole.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Omeprazole.
Rifamycin Rifamycin The metabolism of Rifamycin can be increased when combined with Omeprazole.
Prucalopride Prucalopride The metabolism of Prucalopride can be decreased when combined with Omeprazole.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Omeprazole can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be increased when combined with Omeprazole.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be increased when combined with Omeprazole.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be increased when combined with Omeprazole.
Esomeprazole Injection Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Omeprazole.
Alpelisib Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Omeprazole.
Cladribine Cladribine Omeprazole may decrease the excretion rate of Cladribine which could result in a higher serum level.
Darolutamide Darolutamide Omeprazole may decrease the excretion rate of Darolutamide which could result in a higher serum level.
Triclabendazole Triclabendazole The metabolism of Omeprazole can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The metabolism of Entrectinib can be increased when combined with Omeprazole.
Pexidartinib Pexidartinib The serum concentration of Pexidartinib can be decreased when it is combined with Omeprazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Omeprazole.
Pitolisant Pitolisant The serum concentration of Omeprazole can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Fedratinib can be decreased when combined with Omeprazole.
Lefamulin Lefamulin The metabolism of Lefamulin can be decreased when combined with Omeprazole.
Phenytoin Injection Phenytoin Injection The serum concentration of Phenytoin can be increased when it is combined with Omeprazole.
Fosphenytoin Injection Fosphenytoin Injection The serum concentration of Fosphenytoin can be increased when it is combined with Omeprazole.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Omeprazole.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Omeprazole.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Omeprazole.
Lumateperone Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Omeprazole.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Omeprazole.
Tazemetostat Tazemetostat Omeprazole may decrease the excretion rate of Tazemetostat which could result in a higher serum level.
Cenobamate Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Omeprazole.
Ozanimod Ozanimod Omeprazole may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib Selumetinib Omeprazole may decrease the excretion rate of Selumetinib which could result in a higher serum level.
Rimegepant Rimegepant The metabolism of Rimegepant can be increased when combined with Omeprazole.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Omeprazole.
Ripretinib Ripretinib Omeprazole may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Selpercatinib Selpercatinib The serum concentration of Omeprazole can be decreased when it is combined with Selpercatinib.
Capmatinib Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Omeprazole.
Lemborexant Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Omeprazole.
Fostemsavir Fostemsavir Omeprazole may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Octreotide Octreotide Omeprazole can cause a decrease in the absorption of Octreotide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pralsetinib Pralsetinib Omeprazole may decrease the excretion rate of Pralsetinib which could result in a higher serum level.
Opicapone Opicapone The metabolism of Omeprazole can be decreased when combined with Opicapone.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Omeprazole can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Omeprazole.
Theophylline Theophylline The metabolism of Theophylline can be increased when combined with Omeprazole.
Indomethacin Indomethacin The metabolism of Omeprazole can be decreased when combined with Indomethacin.
Mefenamic Acid Mefenamic Acid The metabolism of Omeprazole can be decreased when combined with Mefenamic acid.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Omeprazole.
Trazodone Trazodone The metabolism of Trazodone can be decreased when combined with Omeprazole.
Floxuridine Floxuridine The metabolism of Omeprazole can be decreased when combined with Floxuridine.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Omeprazole.
Methotrexate Injection Methotrexate Injection The serum concentration of Methotrexate can be increased when it is combined with Omeprazole.
Primidone Primidone The metabolism of Primidone can be decreased when combined with Omeprazole.
Methsuximide Methsuximide The metabolism of Methsuximide can be decreased when combined with Omeprazole.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Omeprazole.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Omeprazole.
Lorazepam Lorazepam The metabolism of Lorazepam can be increased when combined with Omeprazole.
Carmustine Carmustine The metabolism of Carmustine can be increased when combined with Omeprazole.
Codeine Codeine The metabolism of Codeine can be decreased when combined with Omeprazole.
Tranylcypromine Tranylcypromine The metabolism of Omeprazole can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Omeprazole can be decreased when combined with Phenelzine.
Prochlorperazine Prochlorperazine The metabolism of Prochlorperazine can be increased when combined with Omeprazole.
Thioridazine Thioridazine The metabolism of Thioridazine can be decreased when combined with Omeprazole.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be increased when combined with Omeprazole.
Dapsone Dapsone The metabolism of Omeprazole can be decreased when combined with Dapsone.
Sulfadiazine Sulfadiazine The metabolism of Omeprazole can be decreased when combined with Sulfadiazine.
Oxycodone Oxycodone The metabolism of Oxycodone can be decreased when combined with Omeprazole.
Methadone Methadone The metabolism of Omeprazole can be decreased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Omeprazole can be decreased when combined with Oxybutynin.
Benztropine Benztropine The metabolism of Benzatropine can be decreased when combined with Omeprazole.
Maprotiline Maprotiline The metabolism of Maprotiline can be increased when combined with Omeprazole.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Omeprazole.
Perphenazine Perphenazine The metabolism of Perphenazine can be increased when combined with Omeprazole.
Azathioprine Azathioprine The metabolism of Azathioprine can be increased when combined with Omeprazole.
Phentermine Phentermine The metabolism of Phentermine can be increased when combined with Omeprazole.
Methylphenidate Methylphenidate Omeprazole can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Amoxapine Amoxapine The metabolism of Amoxapine can be decreased when combined with Omeprazole.
Sulfasalazine Sulfasalazine Omeprazole may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Hydrocortisone Hydrocortisone The metabolism of Omeprazole can be increased when combined with Hydrocortisone.
Doxorubicin Doxorubicin The metabolism of Doxorubicin can be increased when combined with Omeprazole.
Dactinomycin Dactinomycin Omeprazole may decrease the excretion rate of Dactinomycin which could result in a higher serum level.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be increased when combined with Omeprazole.
Clonidine Clonidine The metabolism of Clonidine can be increased when combined with Omeprazole.
Prazosin Prazosin Omeprazole may decrease the excretion rate of Prazosin which could result in a higher serum level.
Cimetidine Cimetidine The metabolism of Omeprazole can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Warfarin can be increased when combined with Omeprazole.
Clonazepam Clonazepam The metabolism of Clonazepam can be increased when combined with Omeprazole.
Loperamide Loperamide The metabolism of Loperamide can be decreased when combined with Omeprazole.
Promethazine Promethazine The metabolism of Omeprazole can be decreased when combined with Promethazine.
Daunorubicin Daunorubicin Omeprazole may decrease the excretion rate of Daunorubicin which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Omeprazole may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin Griseofulvin The metabolism of Omeprazole can be increased when combined with Griseofulvin.
Methenamine Methenamine The therapeutic efficacy of Methenamine can be decreased when used in combination with Omeprazole.
Digoxin Digoxin The serum concentration of Digoxin can be increased when it is combined with Omeprazole.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Omeprazole.
Quinine Quinine The metabolism of Quinine can be decreased when combined with Omeprazole.
Triamterene Triamterene The metabolism of Triamterene can be increased when combined with Omeprazole.
Sulfinpyrazone Sulfinpyrazone The metabolism of Omeprazole can be decreased when combined with Sulfinpyrazone.
Isosorbide Isosorbide The metabolism of Isosorbide can be increased when combined with Omeprazole.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Omeprazole.
Secobarbital Secobarbital The metabolism of Omeprazole can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Omeprazole.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Omeprazole.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Omeprazole.
Probenecid Probenecid The metabolism of Omeprazole can be decreased when combined with Probenecid.
Quinidine Quinidine The metabolism of Quinidine can be increased when combined with Omeprazole.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Omeprazole.
Isoniazid Isoniazid The metabolism of Omeprazole can be decreased when combined with Isoniazid.
Rifampin Rifampin The serum concentration of Omeprazole can be decreased when it is combined with Rifampicin.
Disopyramide Disopyramide The metabolism of Disopyramide can be increased when combined with Omeprazole.
Valproic Acid Valproic Acid The metabolism of Omeprazole can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be increased when combined with Omeprazole.
Levothyroxine Levothyroxine Omeprazole can cause a decrease in the absorption of Levothyroxine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Methimazole Methimazole The metabolism of Omeprazole can be decreased when combined with Methimazole.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Omeprazole.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Omeprazole.
Tolazamide Tolazamide The metabolism of Tolazamide can be decreased when combined with Omeprazole.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Omeprazole.
Cyclobenzaprine Cyclobenzaprine The metabolism of Cyclobenzaprine can be increased when combined with Omeprazole.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Omeprazole.
Meclizine Meclizine The metabolism of Meclizine can be decreased when combined with Omeprazole.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be increased when combined with Omeprazole.
Carisoprodol Carisoprodol The metabolism of Carisoprodol can be decreased when combined with Omeprazole.
Folic Acid Folic Acid Omeprazole may decrease the excretion rate of Folic acid which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Omeprazole.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be increased when combined with Omeprazole.
Spironolactone Spironolactone The metabolism of Omeprazole can be decreased when combined with Spironolactone.
Nadolol Nadolol The metabolism of Nadolol can be decreased when combined with Omeprazole.
Allopurinol Allopurinol Omeprazole may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Omeprazole.
Colchicine Colchicine The metabolism of Colchicine can be decreased when combined with Omeprazole.
Cephalexin Cephalexin The metabolism of Cephalexin can be increased when combined with Omeprazole.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be increased when combined with Omeprazole.
Iron Supplements Iron Supplements The absorption of Iron can be decreased when combined with Omeprazole.
Ketoconazole Ketoconazole Ketoconazole can cause a decrease in the absorption of Omeprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be increased when combined with Omeprazole.
Vincristine Injection Vincristine Injection The metabolism of Vincristine can be increased when combined with Omeprazole.
Captopril Captopril Captopril can cause a decrease in the absorption of Omeprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Vinblastine Vinblastine The metabolism of Vinblastine can be increased when combined with Omeprazole.
Metoprolol Metoprolol The metabolism of Metoprolol can be increased when combined with Omeprazole.
Thiothixene Thiothixene The metabolism of Thiothixene can be increased when combined with Omeprazole.
Alprazolam Alprazolam The metabolism of Alprazolam can be decreased when combined with Omeprazole.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Omeprazole.
Diltiazem Diltiazem The metabolism of Omeprazole can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Omeprazole can be decreased when combined with Nifedipine.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Omeprazole.
Verapamil Verapamil The metabolism of Omeprazole can be decreased when combined with Verapamil.
Atenolol Atenolol The metabolism of Atenolol can be decreased when combined with Omeprazole.
Pindolol Pindolol The metabolism of Pindolol can be decreased when combined with Omeprazole.
Cisplatin Injection Cisplatin Injection The metabolism of Omeprazole can be decreased when combined with Cisplatin.
Piroxicam Piroxicam The metabolism of Omeprazole can be decreased when combined with Piroxicam.
Etoposide Etoposide The metabolism of Etoposide can be increased when combined with Omeprazole.
Glyburide Glyburide Omeprazole may decrease the excretion rate of Glyburide which could result in a higher serum level.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Omeprazole.
Pentoxifylline Pentoxifylline The metabolism of Pentoxifylline can be increased when combined with Omeprazole.
Pentamidine Injection Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Omeprazole.
Labetalol Labetalol The metabolism of Labetalol can be decreased when combined with Omeprazole.
Gemfibrozil Gemfibrozil The metabolism of Omeprazole can be decreased when combined with Gemfibrozil.
Guanabenz Guanabenz The metabolism of Guanabenz can be increased when combined with Omeprazole.
Ketoprofen Ketoprofen The metabolism of Omeprazole can be decreased when combined with Ketoprofen.
Pimozide Pimozide The metabolism of Pimozide can be increased when combined with Omeprazole.
Flurbiprofen Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Omeprazole.
Amiodarone Amiodarone The metabolism of Amiodarone can be increased when combined with Omeprazole.
Buspirone Buspirone The metabolism of Buspirone can be decreased when combined with Omeprazole.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Omeprazole.
Mesalamine Mesalamine Omeprazole can cause a decrease in the absorption of Mesalazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Omeprazole.
Fluoxetine Fluoxetine The metabolism of Omeprazole can be decreased when combined with Fluoxetine.
Clozapine Clozapine The metabolism of Omeprazole can be decreased when combined with Clozapine.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Omeprazole.
Etodolac Etodolac The metabolism of Etodolac can be decreased when combined with Omeprazole.
Felodipine Felodipine The metabolism of Omeprazole can be decreased when combined with Felodipine.
Nabumetone Nabumetone The metabolism of Nabumetone can be increased when combined with Omeprazole.
Pravastatin Pravastatin Omeprazole may decrease the excretion rate of Pravastatin which could result in a higher serum level.
Simvastatin Simvastatin The metabolism of Omeprazole can be decreased when combined with Simvastatin.
Amlodipine Amlodipine The metabolism of Amlodipine can be increased when combined with Omeprazole.
Teniposide Injection Teniposide Injection The metabolism of Teniposide can be increased when combined with Omeprazole.
Itraconazole Itraconazole Itraconazole can cause a decrease in the absorption of Omeprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Atovaquone Atovaquone The metabolism of Omeprazole can be decreased when combined with Atovaquone.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Omeprazole.
Zolpidem Zolpidem The metabolism of Zolpidem can be increased when combined with Omeprazole.
Doxazosin Doxazosin The metabolism of Doxazosin can be increased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Cisapride can be increased when combined with Omeprazole.
Fluvastatin Fluvastatin The metabolism of Omeprazole can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The metabolism of Omeprazole can be decreased when combined with Venlafaxine.
Famciclovir Famciclovir The metabolism of Famciclovir can be increased when combined with Omeprazole.
Fluvoxamine Fluvoxamine The metabolism of Omeprazole can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Nefazodone can be decreased when combined with Omeprazole.
Losartan Losartan The metabolism of Losartan can be decreased when combined with Omeprazole.
Tramadol Tramadol The metabolism of Tramadol can be decreased when combined with Omeprazole.
Vinorelbine Injection Vinorelbine Injection The metabolism of Vinorelbine can be increased when combined with Omeprazole.
Lansoprazole Lansoprazole The metabolism of Omeprazole can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Omeprazole.
Nicardipine Nicardipine The metabolism of Omeprazole can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Bupropion can be decreased when combined with Omeprazole.
Ticlopidine Ticlopidine The metabolism of Omeprazole can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Omeprazole.
Lamivudine Lamivudine Omeprazole may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole Omeprazole may decrease the excretion rate of Riluzole which could result in a higher serum level.
Glimepiride Glimepiride The metabolism of Omeprazole can be decreased when combined with Glimepiride.
Anastrozole Anastrozole The metabolism of Anastrozole can be decreased when combined with Omeprazole.
Indinavir Indinavir Omeprazole can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ritonavir Ritonavir The serum concentration of Omeprazole can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Omeprazole.
Clomipramine Clomipramine The metabolism of Omeprazole can be increased when combined with Clomipramine.
Zafirlukast Zafirlukast The metabolism of Omeprazole can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine The metabolism of Mirtazapine can be increased when combined with Omeprazole.
Topiramate Topiramate The metabolism of Omeprazole can be decreased when combined with Topiramate.
Zileuton Zileuton The metabolism of Zileuton can be increased when combined with Omeprazole.
Valsartan Valsartan The metabolism of Omeprazole can be decreased when combined with Valsartan.
Donepezil Donepezil Omeprazole may decrease the excretion rate of Donepezil which could result in a higher serum level.
Nelfinavir Nelfinavir The serum concentration of Nelfinavir can be decreased when it is combined with Omeprazole.
Azithromycin Azithromycin The metabolism of Azithromycin can be increased when combined with Omeprazole.
Loratadine Loratadine The metabolism of Omeprazole can be decreased when combined with Loratadine.
Carvedilol Carvedilol The metabolism of Carvedilol can be increased when combined with Omeprazole.
Nilutamide Nilutamide The metabolism of Omeprazole can be decreased when combined with Nilutamide.
Flutamide Flutamide The metabolism of Flutamide can be increased when combined with Omeprazole.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Omeprazole.
Bicalutamide Bicalutamide The metabolism of Omeprazole can be increased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Omeprazole can be decreased when combined with Sertraline.
Propafenone Propafenone The metabolism of Propafenone can be increased when combined with Omeprazole.
Letrozole Letrozole The metabolism of Omeprazole can be decreased when combined with Letrozole.
Raloxifene Raloxifene Omeprazole may decrease the excretion rate of Raloxifene which could result in a higher serum level.
Irbesartan Irbesartan The metabolism of Omeprazole can be decreased when combined with Irbesartan.
Tamsulosin Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Omeprazole.
Ropinirole Ropinirole The risk or severity of adverse effects can be increased when Omeprazole is combined with Ropinirole.
Quetiapine Quetiapine The metabolism of Quetiapine can be decreased when combined with Omeprazole.
Paroxetine Paroxetine The metabolism of Omeprazole can be decreased when combined with Paroxetine.
Tolcapone Tolcapone The metabolism of Omeprazole can be decreased when combined with Tolcapone.
Citalopram Citalopram The risk or severity of QTc prolongation can be increased when Omeprazole is combined with Citalopram.
Capecitabine Capecitabine The metabolism of Omeprazole can be decreased when combined with Capecitabine.
Efavirenz Efavirenz The metabolism of Omeprazole can be increased when combined with Efavirenz.
Sildenafil Sildenafil The metabolism of Omeprazole can be decreased when combined with Sildenafil.
Pioglitazone Pioglitazone The metabolism of Omeprazole can be decreased when combined with Pioglitazone.
Celecoxib Celecoxib Omeprazole may decrease the excretion rate of Celecoxib which could result in a higher serum level.
Rosiglitazone Rosiglitazone The metabolism of Omeprazole can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Omeprazole.
Thalidomide Thalidomide The metabolism of Omeprazole can be decreased when combined with Thalidomide.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Omeprazole.
Galantamine Galantamine The metabolism of Galantamine can be decreased when combined with Omeprazole.
Rabeprazole Rabeprazole The metabolism of Omeprazole can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Terbinafine can be decreased when combined with Omeprazole.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists