Interaction Question: Omeprazole, Spironolactone And Phentermine

Answer

Thank you for your question! I'm glad to help.

There is no known interaction between phentermine, spironolactone, and omeprazole. However, there are a few important things to consider:

• Omeprazole has specific administration instructions for optimal effects.
• Phentermine and spironolactone may have opposing actions on blood pressure.

Details

First and foremost, it is important to take omeprazole correctly to get the best effects from it.

Generally, it should be taken 30-60 minutes before a meal and other medications. This allows it to get into your system and inhibit the proton pumps before food or other medications enter your system.

Secondly, I don't know why you are taking spironolactone, but if it is for blood pressure, it is important to note that phentermine, being a stimulant and similar to amphetamines, can increase blood pressure. Amphetamines are known to cause modest increases in average blood pressure (BP) and heart rate (HR).

For example, one review of amphetamines in adults noted that amphetamines increased systolic blood pressure (the top number on a blood pressure reading) by 8.4 mm Hg and diastolic blood pressure (the lower number) by 4.9 mm Hg. Additionally, the study found that heart rate increased an average of 10.6 beats per minute.

If you are taking spironolactone for something else, like acne, this opposing effect on blood pressure likely isn't a clinically significant concern for you.

I looked up 'Cellcore' supplements and it looks like there are quite a few available. I am unsure of which you are referring to, so feel free to submit another question with specifics. Additionally, you can take a look at the ingredients in these supplements and look them up individually on our interaction checker (Drug-Herb Interactions).

Final Words

Thanks again for reaching out, and please feel free to do so again anytime!