Lansoprazole

Prescription lansoprazole is used to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 1 year of age and older. Prescription lansoprazole is used to treat the damage from GERD in adults and children 1 year of age and older. Prescription lansoprazole is used to allow the esophagus to heal and prevent further damage to the esophagus in adults with GERD. Prescription lansoprazole is also used to treat ulcers (sores in the lining of the stomach or intestine), to prevent more ulcers from developing in adults whose ulcers have already healed, and to decrease the risk that adults who are taking nonsteroidal anti-inflammatory drugs (NSAIDs) will develop ulcers. Prescription lansoprazole is also used to treat conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome in adults. Prescription lansoprazole is also used in combination with other medications to treat and prevent stomach ulcers caused by a certain type of bacteria (H. pylori) in adults. Nonprescription (over-the-counter) lansoprazole is used to treat frequent heartburn (heartburn that occurs two or more days per week) in adults. Lansoprazole is in a class of medications called proton pump inhibitors. It works by decreasing the amount of acid made in the stomach.

Prescription lansoprazole comes as a delayed-release (releases the medication in the intestine to prevent break-down of the medication by stomach acids) capsule and as a delayed-release orally disintegrating (dissolving) tablet to take by mouth. Nonprescription lansoprazole comes as a delayed-release capsule to take by mouth. Prescription lansoprazole is usually taken once a day, before a meal. When taken in combination with other medications to eliminate H. pylori, prescription lansoprazole is taken twice a day (every 12 hours) or three times a day (every 8 hours), before a meal, for 10 to 14 days. Nonprescription lansoprazole is usually taken once a day, in the morning before eating for 14 days. If needed, additional 14-day treatments may be repeated, not more often than once every 4 months. Take lansoprazole at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lansoprazole exactly as directed. Do not take more or less of it or take it more often or for a longer time than prescribed by your doctor or stated on the package. Tell your doctor if you have taken nonprescription lansoprazole for a longer period of time than stated on the package.

Swallow the prescription capsules whole; do not split, chew, or crush them. If you have difficulty swallowing capsules, you may open the capsule, sprinkle the granules on 1 tablespoon of applesauce, Ensure^® pudding, cottage cheese, yogurt, or strained pears and swallow the mixture immediately without chewing. You can also open a capsule and pour the contents into 2 ounces (60 milliliters) of orange juice, apple juice or tomato juice, mix briefly, and swallow immediately. After you swallow the mixture, rinse the glass with some additional juice and drink immediately. Then rinse the glass with juice at least two more times and drink the juice to be sure that you wash all the medication out of the glass.

Swallow the nonprescription capsules whole with a glass of water. Do not split, chew, or crush them.

Do not break, cut or chew the orally disintegrating tablets. Place a tablet on your tongue and wait up to one minute for it to dissolve. After the tablet dissolves, swallow it with or without water. If you cannot swallow the tablet, you may place it in an oral syringe, draw up 4 mL of water for a 15 mg tablet or 10 mL of water for a 30-mg tablet, shake the syringe gently to dissolve the tablet, and squirt the contents into your mouth immediately. Then draw an additional 2 mL of water into the syringe, shake gently, and squirt that water into your mouth. Do not swallow the mixture more than 15 minutes after you dissolve the tablet.

The capsule contents and orally disintegrating tablets can both be given through a feeding tube. If you have a feeding tube, ask your doctor how you should take the medication. Follow these directions carefully.

Do not take nonprescription lansoprazole for immediate relief of heartburn symptoms. It may take 1 to 4 days for you to feel the full benefit of the medication. Call your doctor if your symptoms get worse or do not improve after 14 days or if your symptoms return sooner than 4 months after you finish your treatment. Do not take nonprescription lansoprazole for longer than 14 days or treat yourself with lansoprazole more often than once every 4 months without talking to your doctor.

Continue to take lansoprazole even if you feel well. Do not stop taking prescription lansoprazole without talking to your doctor. If your condition does not improve or gets worse, call your doctor.

Ask your doctor or pharmacist for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking lansoprazole,

• tell your doctor and pharmacist if you are allergic to lansoprazole, any other medications, or any of the ingredients in lansoprazole capsules or orally disintegrating tablets. Ask your doctor or pharmacist for a list of the ingredients.

• tell your doctor if you are taking rilpivirine (Edurant, in Cabenuva, Complera, Juluca, Odefsey). Your doctor will probably tell you not to take lansoprazole if you are taking this medication.

• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: certain antibiotics, including anticoagulants (blood thinners) such as warfarin (Jantoven), atazanavir (Reyataz, in Evotaz), dasatinib (Sprycel), digoxin (Lanoxin), diuretics ('water pills'), erlotinib (Tarceva), iron supplements, itraconazole (Sporonox, Tolsura), ketoconazole, methotrexate (Trexall, Xatmep), mycophenolate mofetil (Cellcept, Myfortic), nelfinavir (Viracept), nilotinib (Tasigna), rifampin (Rifadin, Rimactane), ritonavir (Norvir, in Kaletra), saquinavir (Invirase), tacrolimus (Astagraf, Envarsus, Prograf), theophylline (Theo-24), and voriconazole (Vfend). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

• tell your doctor what herbal products you are taking, especially St. John's wort. Your doctor may tell you not to take St. John's wort while taking lansoprazole.

• if you are taking sucralfate (Carafate), take it at least 30 minutes after you take lansoprazole.

• tell your doctor if you have or have ever had a low level of magnesium, calcium, potassium, or sodium in your blood; hypoparathyroidism (condition in which the body does not produce enough parathyroid hormone [PTH; a natural substance needed to control the amount of calcium in the blood]); low levels of vitamin B12 in your body; osteoporosis (a condition in which the bones become thin and weak and break easily); an autoimmune disease (condition in which the body attacks its own organs, causing swelling and loss of function) such as systemic lupus erythematosus; or liver disease.

• if you plan to take nonprescription lansoprazole, first tell your doctor if your heartburn has lasted 3 months or longer or if you have experienced any of the following symptoms: lightheadedness, sweating, or dizziness along with your heartburn; chest pain or shoulder pain; shortness of breath or wheezing; pain that spreads to your arms, neck, or shoulders; unexplained weight loss; nausea; vomiting, especially if the vomit is bloody; stomach pain; difficulty swallowing food or pain when you swallow food; or black or bloody stools. You may have a more serious condition that cannot be treated with a nonprescription medication.

• tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking lansoprazole, call your doctor.

• if you are 70 years of age or older, do not take this medication for a longer period of time than recommended on the product label or by your doctor.

• if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that the orally disintegrating tablets may contain aspartame, which forms phenylalanine.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your dosing schedule. Do not take a double dose to make up for a missed one.

• Lansoprazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • constipation

  • nausea

  • headache

  • dizziness

  • diarrhea

• Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

  • rash; hives; itching; swelling of the eyes, face, lips, mouth, throat, or tongue; difficulty breathing or swallowing; hoarseness

  • blistering, peeling, or bleeding skin; sores on the lips, nose, mouth, or genitals; swollen glands; shortness of breath; fever; flu-like symptoms

  • increased or decreased urination, blood in urine, fatigue, nausea, loss of appetite, fever, rash, or joint pain

  • irregular, fast, or pounding heartbeat; muscle spasms; uncontrollable shaking of a part of the body; excessive tiredness; lightheadedness; dizziness; or seizures

  • severe diarrhea with watery stools, stomach pain, or fever that does not go away

  • new or worsening joint pain; rash on cheeks or arms that is sensitive to sunlight

• Lansoprazole may cause other side effects. Call your doctor if you have any unusual problems while you are taking the medication.

• People who take proton pump inhibitors such as lansoprazole may be more likely to fracture their wrists, hips, or spine than people who do not take one of these medications. People who take proton pump inhibitors may also develop fundic gland polyps (a type of growth on the stomach lining). These risks are highest in people who take high doses of one of these medications or take them for 1 year or longer. Talk to your doctor about the risk of taking lansoprazole.

• If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain laboratory tests before and during your treatment.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking lansoprazole.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

• Prevacid^® NapraPAC^® (containing Lansoprazole, Naproxen)

Drug	Interaction
Repaglinide	Repaglinide The metabolism of Repaglinide can be decreased when combined with Lansoprazole.
Montelukast	Montelukast The metabolism of Lansoprazole can be decreased when combined with Montelukast.
Leflunomide	Leflunomide Lansoprazole may decrease the excretion rate of Leflunomide which could result in a higher serum level.
Delavirdine	Delavirdine Delavirdine can cause a decrease in the absorption of Lansoprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nevirapine	Nevirapine The metabolism of Lansoprazole can be decreased when combined with Nevirapine.
Atorvastatin	Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Lansoprazole.
Dolasetron	Dolasetron The metabolism of Dolasetron can be decreased when combined with Lansoprazole.
Alendronate	Alendronate The therapeutic efficacy of Alendronic acid can be decreased when used in combination with Lansoprazole.
Aminophylline	Aminophylline The metabolism of Aminophylline can be increased when combined with Lansoprazole.
Bisacodyl	Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Lansoprazole.
Candesartan	Candesartan The metabolism of Lansoprazole can be decreased when combined with Candesartan.
Cilostazol	Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Lansoprazole.
Clopidogrel	Clopidogrel The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Lansoprazole resulting in a loss in efficacy.
Estrogen and Progestin (Oral Contraceptives)	Estrogen and Progestin (Oral Contraceptives) The excretion of Conjugated estrogens can be decreased when combined with Lansoprazole.
Fenofibrate	Fenofibrate The metabolism of Fenofibrate can be increased when combined with Lansoprazole.
Mycophenolate	Mycophenolate Lansoprazole can cause a decrease in the absorption of Mycophenolic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Paregoric	Paregoric The metabolism of Lansoprazole can be decreased when combined with Morphine.
Penbutolol	Penbutolol The metabolism of Acebutolol can be decreased when combined with Lansoprazole.
Ranitidine	Ranitidine The excretion of Ranitidine can be decreased when combined with Lansoprazole.
Sumatriptan	Sumatriptan Lansoprazole may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus	Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Lansoprazole.
Tiludronate	Tiludronate The therapeutic efficacy of Etidronic acid can be decreased when used in combination with Lansoprazole.
Famotidine Injection	Famotidine Injection The excretion of Famotidine can be decreased when combined with Lansoprazole.
Fluconazole Injection	Fluconazole Injection The metabolism of Lansoprazole can be decreased when combined with Fluconazole.
Hydromorphone Injection	Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Lansoprazole.
Meperidine Injection	Meperidine Injection The metabolism of Meperidine can be increased when combined with Lansoprazole.
Metoclopramide Injection	Metoclopramide Injection The metabolism of Metoclopramide can be decreased when combined with Lansoprazole.
Metronidazole Injection	Metronidazole Injection The metabolism of Lansoprazole can be decreased when combined with Metronidazole.
Morphine Injection	Morphine Injection The metabolism of Lansoprazole can be decreased when combined with Morphine.
Zidovudine Injection	Zidovudine Injection The excretion of Zidovudine can be decreased when combined with Lansoprazole.
Altretamine	Altretamine Lansoprazole can cause an increase in the absorption of Amphetamine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Cefuroxime	Cefuroxime The serum concentration of Cefuroxime can be decreased when it is combined with Lansoprazole.
Cyclosporine	Cyclosporine The metabolism of Cyclosporine can be increased when combined with Lansoprazole.
Ondansetron	Ondansetron The metabolism of Ondansetron can be decreased when combined with Lansoprazole.
Torsemide	Torsemide The metabolism of Lansoprazole can be decreased when combined with Torasemide.
Olanzapine	Olanzapine The metabolism of Lansoprazole can be decreased when combined with Olanzapine.
Alosetron	Alosetron The metabolism of Alosetron can be decreased when combined with Lansoprazole.
Dofetilide	Dofetilide The metabolism of Dofetilide can be increased when combined with Lansoprazole.
Hydroxychloroquine	Hydroxychloroquine The metabolism of Hydroxychloroquine can be decreased when combined with Lansoprazole.
Meloxicam	Meloxicam The metabolism of Meloxicam can be decreased when combined with Lansoprazole.
Oxcarbazepine	Oxcarbazepine The metabolism of Lansoprazole can be decreased when combined with Oxcarbazepine.
Pantoprazole	Pantoprazole The metabolism of Pantoprazole can be decreased when combined with Lansoprazole.
Risedronate	Risedronate Lansoprazole can cause an increase in the absorption of Risedronic acid resulting in an increased serum concentration and potentially a worsening of adverse effects.
Telmisartan	Telmisartan The metabolism of Lansoprazole can be decreased when combined with Telmisartan.
Anakinra	Anakinra The metabolism of Lansoprazole can be increased when combined with Anakinra.
Trimipramine	Trimipramine The metabolism of Trimipramine can be decreased when combined with Lansoprazole.
Etanercept Injection	Etanercept Injection The metabolism of Lansoprazole can be increased when combined with Etanercept.
Modafinil	Modafinil The metabolism of Lansoprazole can be decreased when combined with Modafinil.
Tenofovir	Tenofovir The metabolism of Tenofovir can be increased when combined with Lansoprazole.
Sirolimus	Sirolimus The metabolism of Sirolimus can be increased when combined with Lansoprazole.
Epinephrine Injection	Epinephrine Injection The metabolism of Lansoprazole can be decreased when combined with Epinephrine.
Escitalopram	Escitalopram The metabolism of Escitalopram can be decreased when combined with Lansoprazole.
Zonisamide	Zonisamide The metabolism of Zonisamide can be decreased when combined with Lansoprazole.
Adalimumab Injection	Adalimumab Injection The metabolism of Lansoprazole can be increased when combined with Adalimumab.
Aripiprazole	Aripiprazole The metabolism of Aripiprazole can be increased when combined with Lansoprazole.
Atomoxetine	Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Lansoprazole.
Dexmethylphenidate	Dexmethylphenidate Lansoprazole can cause an increase in the absorption of Dexmethylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Ezetimibe	Ezetimibe Lansoprazole may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Atazanavir	Atazanavir The therapeutic efficacy of Atazanavir can be decreased when used in combination with Lansoprazole.
Almotriptan	Almotriptan The metabolism of Almotriptan can be decreased when combined with Lansoprazole.
Eletriptan	Eletriptan The metabolism of Eletriptan can be decreased when combined with Lansoprazole.
Rosuvastatin	Rosuvastatin Lansoprazole may decrease the excretion rate of Rosuvastatin which could result in a higher serum level.
Vardenafil	Vardenafil The metabolism of Vardenafil can be decreased when combined with Lansoprazole.
Alfuzosin	Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Lansoprazole.
Aprepitant	Aprepitant The metabolism of Lansoprazole can be decreased when combined with Aprepitant.
Memantine	Memantine Memantine may decrease the excretion rate of Lansoprazole which could result in a higher serum level.
Tegaserod	Tegaserod Lansoprazole may decrease the excretion rate of Tegaserod which could result in a higher serum level.
Fosamprenavir	Fosamprenavir Lansoprazole can cause a decrease in the absorption of Fosamprenavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Progesterone	Progesterone The metabolism of Progesterone can be decreased when combined with Lansoprazole.
Apomorphine Injection	Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Lansoprazole.
Infliximab Injection	Infliximab Injection The metabolism of Lansoprazole can be increased when combined with Infliximab.
Oxandrolone	Oxandrolone The metabolism of Lansoprazole can be decreased when combined with Oxandrolone.
Protriptyline	Protriptyline The metabolism of Protriptyline can be decreased when combined with Lansoprazole.
Rifaximin	Rifaximin The metabolism of Lansoprazole can be increased when combined with Rifaximin.
Duloxetine	Duloxetine The metabolism of Duloxetine can be increased when combined with Lansoprazole.
Norethindrone	Norethindrone The metabolism of Norethisterone can be increased when combined with Lansoprazole.
Bosentan	Bosentan The metabolism of Bosentan can be decreased when combined with Lansoprazole.
Cefditoren	Cefditoren The excretion of Cefdinir can be decreased when combined with Lansoprazole.
Erlotinib	Erlotinib Lansoprazole can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Eszopiclone	Eszopiclone The serum concentration of Eszopiclone can be decreased when it is combined with Lansoprazole.
Solifenacin	Solifenacin The metabolism of Solifenacin can be decreased when combined with Lansoprazole.
Voriconazole	Voriconazole The metabolism of Lansoprazole can be decreased when combined with Voriconazole.
Dextroamphetamine	Dextroamphetamine Lansoprazole can cause an increase in the absorption of Amphetamine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Peginterferon Alfa-2b (PEG-Intron)	Peginterferon Alfa-2b (PEG-Intron) The metabolism of Lansoprazole can be increased when combined with Peginterferon alfa-2b.
Ibandronate	Ibandronate The therapeutic efficacy of Ibandronate can be decreased when used in combination with Lansoprazole.
Ramelteon	Ramelteon The metabolism of Ramelteon can be decreased when combined with Lansoprazole.
Darifenacin	Darifenacin The metabolism of Darifenacin can be decreased when combined with Lansoprazole.
Fentanyl	Fentanyl The metabolism of Fentanyl can be decreased when combined with Lansoprazole.
Deferasirox	Deferasirox The metabolism of Lansoprazole can be decreased when combined with Deferasirox.
Tipranavir	Tipranavir The metabolism of Lansoprazole can be decreased when combined with Tipranavir.
Felbamate	Felbamate The metabolism of Lansoprazole can be decreased when combined with Felbamate.
Ranolazine	Ranolazine The metabolism of Lansoprazole can be increased when combined with Ranolazine.
Abatacept Injection	Abatacept Injection The metabolism of Lansoprazole can be increased when combined with Abatacept.
Imatinib	Imatinib Lansoprazole may increase the dermatologic adverse activities of Imatinib.
Sitagliptin	Sitagliptin The excretion of Sitagliptin can be decreased when combined with Lansoprazole.
Gefitinib	Gefitinib Lansoprazole can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Paliperidone	Paliperidone The metabolism of Paliperidone can be decreased when combined with Lansoprazole.
Bortezomib	Bortezomib The metabolism of Lansoprazole can be increased when combined with Bortezomib.
Clofarabine Injection	Clofarabine Injection The excretion of Clofarabine can be decreased when combined with Lansoprazole.
Oxaliplatin Injection	Oxaliplatin Injection Lansoprazole may decrease the excretion rate of Oxaliplatin which could result in a higher serum level.
Posaconazole	Posaconazole Lansoprazole can cause a decrease in the absorption of Posaconazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Darunavir	Darunavir Lansoprazole can cause a decrease in the absorption of Darunavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pemetrexed Injection	Pemetrexed Injection The excretion of Pemetrexed can be decreased when combined with Lansoprazole.
Lisdexamfetamine	Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Lansoprazole.
Nabilone	Nabilone The metabolism of Lansoprazole can be decreased when combined with Nabilone.
Retapamulin	Retapamulin The metabolism of Retapamulin can be decreased when combined with Lansoprazole.
Sorafenib	Sorafenib The metabolism of Lansoprazole can be increased when combined with Sorafenib.
Sunitinib	Sunitinib The metabolism of Sunitinib can be increased when combined with Lansoprazole.
Dronabinol	Dronabinol The metabolism of Dronabinol can be decreased when combined with Lansoprazole.
Lapatinib	Lapatinib The metabolism of Lapatinib can be decreased when combined with Lansoprazole.
Dasatinib	Dasatinib Lansoprazole can cause a decrease in the absorption of Dasatinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Mexiletine	Mexiletine The metabolism of Mexiletine can be decreased when combined with Lansoprazole.
Armodafinil	Armodafinil The metabolism of Lansoprazole can be decreased when combined with Armodafinil.
Ivermectin	Ivermectin Lansoprazole may decrease the excretion rate of Ivermectin which could result in a higher serum level.
Temsirolimus	Temsirolimus The metabolism of Temsirolimus can be increased when combined with Lansoprazole.
Nilotinib	Nilotinib The serum concentration of Lansoprazole can be decreased when it is combined with Nilotinib.
Raltegravir	Raltegravir Lansoprazole can cause an increase in the absorption of Raltegravir resulting in an increased serum concentration and potentially a worsening of adverse effects.
Bexarotene	Bexarotene The metabolism of Lansoprazole can be decreased when combined with Bexarotene.
Budesonide	Budesonide Lansoprazole can cause a decrease in the absorption of Budesonide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Chloramphenicol Injection	Chloramphenicol Injection The metabolism of Lansoprazole can be decreased when combined with Chloramphenicol.
Doripenem Injection	Doripenem Injection The excretion of Doripenem can be decreased when combined with Lansoprazole.
Etravirine	Etravirine The metabolism of Etravirine can be decreased when combined with Lansoprazole.
Mitoxantrone Injection	Mitoxantrone Injection Lansoprazole may decrease the excretion rate of Mitoxantrone which could result in a higher serum level.
Cevimeline	Cevimeline The metabolism of Cevimeline can be decreased when combined with Lansoprazole.
Nebivolol	Nebivolol The metabolism of Nebivolol can be decreased when combined with Lansoprazole.
Tretinoin	Tretinoin The metabolism of Tretinoin can be decreased when combined with Lansoprazole.
Leucovorin Injection	Leucovorin Injection The excretion of Leucovorin can be decreased when combined with Lansoprazole.
Flecainide	Flecainide The metabolism of Lansoprazole can be decreased when combined with Flecainide.
Certolizumab Injection	Certolizumab Injection The metabolism of Lansoprazole can be increased when combined with Certolizumab pegol.
Ixabepilone Injection	Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Lansoprazole.
Irinotecan Injection	Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Lansoprazole.
Praziquantel	Praziquantel The metabolism of Praziquantel can be decreased when combined with Lansoprazole.
Rufinamide	Rufinamide The metabolism of Rufinamide can be increased when combined with Lansoprazole.
Midazolam	Midazolam The serum concentration of Midazolam can be increased when it is combined with Lansoprazole.
Eltrombopag	Eltrombopag The metabolism of Lansoprazole can be decreased when combined with Eltrombopag.
Milnacipran	Milnacipran The metabolism of Milnacipran can be increased when combined with Lansoprazole.
Dexlansoprazole	Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Lansoprazole.
Fesoterodine	Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Lansoprazole.
Betaxolol	Betaxolol The metabolism of Betaxolol can be decreased when combined with Lansoprazole.
Iloperidone	Iloperidone The metabolism of Iloperidone can be decreased when combined with Lansoprazole.
Prasugrel	Prasugrel The metabolism of Prasugrel can be decreased when combined with Lansoprazole.
Lacosamide	Lacosamide The metabolism of Lacosamide can be decreased when combined with Lansoprazole.
Everolimus	Everolimus The metabolism of Everolimus can be increased when combined with Lansoprazole.
Tolvaptan (low blood sodium)	Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be increased when combined with Lansoprazole.
Dronedarone	Dronedarone The metabolism of Dronedarone can be increased when combined with Lansoprazole.
Pralatrexate Injection	Pralatrexate Injection Lansoprazole may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection	Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Lansoprazole.
Saxagliptin	Saxagliptin The excretion of Saxagliptin can be decreased when combined with Lansoprazole.
Romidepsin Injection	Romidepsin Injection The metabolism of Romidepsin can be increased when combined with Lansoprazole.
Tapentadol	Tapentadol The metabolism of Tapentadol can be decreased when combined with Lansoprazole.
Topotecan	Topotecan Lansoprazole may decrease the excretion rate of Topotecan which could result in a higher serum level.
Golimumab Injection	Golimumab Injection The metabolism of Lansoprazole can be increased when combined with Golimumab.
Pazopanib	Pazopanib Lansoprazole can cause a decrease in the absorption of Pazopanib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pitavastatin	Pitavastatin Lansoprazole may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole	Albendazole The metabolism of Albendazole can be decreased when combined with Lansoprazole.
Ulipristal	Ulipristal The metabolism of Ulipristal can be increased when combined with Lansoprazole.
Levonorgestrel	Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Lansoprazole.
Oxymorphone	Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Lansoprazole.
Tocilizumab Injection	Tocilizumab Injection The metabolism of Lansoprazole can be increased when combined with Tocilizumab.
Cabazitaxel Injection	Cabazitaxel Injection The metabolism of Cabazitaxel can be increased when combined with Lansoprazole.
Acetaminophen Injection	Acetaminophen Injection The metabolism of Acetaminophen can be decreased when combined with Lansoprazole.
Vilazodone	Vilazodone The metabolism of Vilazodone can be decreased when combined with Lansoprazole.
Busulfan Injection	Busulfan Injection The metabolism of Busulfan can be increased when combined with Lansoprazole.
Roflumilast	Roflumilast The metabolism of Roflumilast can be increased when combined with Lansoprazole.
Linagliptin	Linagliptin The metabolism of Linagliptin can be increased when combined with Lansoprazole.
Rilpivirine	Rilpivirine Lansoprazole can cause a decrease in the absorption of Rilpivirine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Telaprevir	Telaprevir Lansoprazole may decrease the excretion rate of Glecaprevir which could result in a higher serum level.
Cyclophosphamide Injection	Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Lansoprazole.
Abiraterone	Abiraterone The metabolism of Lansoprazole can be decreased when combined with Abiraterone.
Rivaroxaban	Rivaroxaban Lansoprazole may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ticagrelor	Ticagrelor The metabolism of Lansoprazole can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection	Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Lansoprazole.
Ruxolitinib	Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Lansoprazole.
Vandetanib	Vandetanib The metabolism of Vandetanib can be increased when combined with Lansoprazole.
Clobazam	Clobazam The metabolism of Clobazam can be decreased when combined with Lansoprazole.
Vemurafenib	Vemurafenib The metabolism of Vemurafenib can be increased when combined with Lansoprazole.
Vismodegib	Vismodegib The metabolism of Vismodegib can be decreased when combined with Lansoprazole.
Axitinib	Axitinib The metabolism of Axitinib can be increased when combined with Lansoprazole.
Crizotinib	Crizotinib The metabolism of Crizotinib can be increased when combined with Lansoprazole.
Cabergoline	Cabergoline The metabolism of Cabergoline can be increased when combined with Lansoprazole.
Enzalutamide	Enzalutamide The metabolism of Lansoprazole can be increased when combined with Enzalutamide.
Mirabegron	Mirabegron The metabolism of Mirabegron can be decreased when combined with Lansoprazole.
Regorafenib	Regorafenib The metabolism of Lansoprazole can be increased when combined with Regorafenib.
Bosutinib	Bosutinib Bosutinib can cause a decrease in the absorption of Lansoprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Teriflunomide	Teriflunomide Lansoprazole may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Cabozantinib (thyroid cancer)	Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Lansoprazole.
Tofacitinib	Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Lansoprazole.
Alogliptin	Alogliptin The metabolism of Alogliptin can be decreased when combined with Lansoprazole.
Ponatinib	Ponatinib The metabolism of Ponatinib can be increased when combined with Lansoprazole.
Pomalidomide	Pomalidomide The metabolism of Pomalidomide can be increased when combined with Lansoprazole.
Ado-trastuzumab Emtansine Injection	Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be increased when combined with Lansoprazole.
Apixaban	Apixaban The metabolism of Apixaban can be decreased when combined with Lansoprazole.
Dabrafenib	Dabrafenib The serum concentration of Lansoprazole can be decreased when it is combined with Dabrafenib.
Ospemifene	Ospemifene The metabolism of Ospemifene can be decreased when combined with Lansoprazole.
Trametinib	Trametinib The metabolism of Lansoprazole can be decreased when combined with Trametinib.
Dolutegravir	Dolutegravir Lansoprazole may decrease the excretion rate of Dolutegravir which could result in a higher serum level.
Afatinib	Afatinib Lansoprazole may decrease the excretion rate of Afatinib which could result in a higher serum level.
Levomilnacipran	Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Lansoprazole.
Vortioxetine	Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Lansoprazole.
Perampanel	Perampanel The metabolism of Perampanel can be increased when combined with Lansoprazole.
Ibrutinib	Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Lansoprazole.
Lomitapide	Lomitapide The metabolism of Lomitapide can be increased when combined with Lansoprazole.
Ketorolac Injection	Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Lansoprazole.
Simeprevir	Simeprevir Lansoprazole may decrease the excretion rate of Simeprevir which could result in a higher serum level.
Sofosbuvir	Sofosbuvir Lansoprazole may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin	Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Lansoprazole.
Iron Sucrose Injection	Iron Sucrose Injection Lansoprazole can cause a decrease in the absorption of Iron sucrose resulting in a reduced serum concentration and potentially a decrease in efficacy.
Apremilast	Apremilast The metabolism of Lansoprazole can be increased when combined with Apremilast.
Ceritinib	Ceritinib The metabolism of Ceritinib can be increased when combined with Lansoprazole.
Siltuximab Injection	Siltuximab Injection The metabolism of Lansoprazole can be increased when combined with Siltuximab.
Eslicarbazepine	Eslicarbazepine The metabolism of Lansoprazole can be decreased when combined with Eslicarbazepine.
Iron Dextran Injection	Iron Dextran Injection Lansoprazole can cause a decrease in the absorption of Iron Dextran resulting in a reduced serum concentration and potentially a decrease in efficacy.
Idelalisib	Idelalisib The metabolism of Idelalisib can be increased when combined with Lansoprazole.
Testosterone Injection	Testosterone Injection The metabolism of Lansoprazole can be decreased when combined with Testosterone.
Oritavancin Injection	Oritavancin Injection The metabolism of Lansoprazole can be decreased when combined with Oritavancin.
Vorapaxar	Vorapaxar The metabolism of Vorapaxar can be increased when combined with Lansoprazole.
Hydrocodone	Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Lansoprazole.
Suvorexant	Suvorexant The metabolism of Suvorexant can be increased when combined with Lansoprazole.
Olaparib	Olaparib The metabolism of Olaparib can be increased when combined with Lansoprazole.
Methamphetamine	Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Lansoprazole.
Tasimelteon	Tasimelteon The metabolism of Tasimelteon can be increased when combined with Lansoprazole.
Riociguat	Riociguat Lansoprazole can cause a decrease in the absorption of Riociguat resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nintedanib	Nintedanib The metabolism of Nintedanib can be increased when combined with Lansoprazole.
Secukinumab Injection	Secukinumab Injection The metabolism of Lansoprazole can be increased when combined with Secukinumab.
Risperidone Injection	Risperidone Injection The metabolism of Risperidone can be decreased when combined with Lansoprazole.
Palbociclib	Palbociclib The absorption of Palbociclib can be decreased when combined with Lansoprazole.
Lenvatinib	Lenvatinib Lansoprazole may decrease the excretion rate of Lenvatinib which could result in a higher serum level.
Naloxegol	Naloxegol The metabolism of Lansoprazole can be decreased when combined with Naloxegol.
Panobinostat	Panobinostat The metabolism of Panobinostat can be increased when combined with Lansoprazole.
Haloperidol Injection	Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Lansoprazole.
Sonidegib	Sonidegib The metabolism of Sonidegib can be increased when combined with Lansoprazole.
Flibanserin	Flibanserin The serum concentration of Flibanserin can be increased when it is combined with Lansoprazole.
Brexpiprazole	Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Lansoprazole.
Ziprasidone Injection	Ziprasidone Injection The metabolism of Ziprasidone can be increased when combined with Lansoprazole.
Cariprazine	Cariprazine The metabolism of Cariprazine can be decreased when combined with Lansoprazole.
Eluxadoline	Eluxadoline The excretion of Eluxadoline can be decreased when combined with Lansoprazole.
Cobimetinib	Cobimetinib The metabolism of Cobimetinib can be increased when combined with Lansoprazole.
Trabectedin Injection	Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Lansoprazole.
Osimertinib	Osimertinib The metabolism of Osimertinib can be increased when combined with Lansoprazole.
Alectinib	Alectinib The metabolism of Alectinib can be increased when combined with Lansoprazole.
Ixazomib	Ixazomib The metabolism of Ixazomib can be increased when combined with Lansoprazole.
Rifapentine	Rifapentine The metabolism of Lansoprazole can be increased when combined with Rifapentine.
Lesinurad	Lesinurad The metabolism of Lesinurad can be decreased when combined with Lansoprazole.
Dexamethasone Injection	Dexamethasone Injection The excretion of Dexamethasone can be decreased when combined with Lansoprazole.
Brivaracetam Injection	Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Lansoprazole.
Venetoclax	Venetoclax The metabolism of Venetoclax can be increased when combined with Lansoprazole.
Selexipag	Selexipag The metabolism of Selexipag can be decreased when combined with Lansoprazole.
Diphenhydramine Injection	Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Lansoprazole.
Rucaparib	Rucaparib Lansoprazole may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Ribociclib	Ribociclib The metabolism of Ribociclib can be increased when combined with Lansoprazole.
Brigatinib	Brigatinib The metabolism of Brigatinib can be increased when combined with Lansoprazole.
Doxepin (Insomnia)	Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Lansoprazole.
Deutetrabenazine	Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Lansoprazole.
Valbenazine	Valbenazine The metabolism of Valbenazine can be decreased when combined with Lansoprazole.
Safinamide	Safinamide The metabolism of Lansoprazole can be decreased when combined with Safinamide.
Edaravone Injection	Edaravone Injection The excretion of Edaravone can be decreased when combined with Lansoprazole.
Midostaurin	Midostaurin The metabolism of Lansoprazole can be increased when combined with Midostaurin.
Neratinib	Neratinib The metabolism of Neratinib can be increased when combined with Lansoprazole.
Enasidenib	Enasidenib The metabolism of Enasidenib can be increased when combined with Lansoprazole.
Aprepitant/Fosaprepitant Injection	Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Lansoprazole.
Copanlisib Injection	Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Lansoprazole.
Delafloxacin	Delafloxacin Lansoprazole may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib	Abemaciclib The metabolism of Abemaciclib can be increased when combined with Lansoprazole.
Acalabrutinib	Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Lansoprazole.
Letermovir	Letermovir The metabolism of Lansoprazole can be decreased when combined with Letermovir.
Tetrabenazine	Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Lansoprazole.
Ertugliflozin	Ertugliflozin Lansoprazole may decrease the excretion rate of Ertugliflozin which could result in a higher serum level.
Buprenorphine Injection	Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Lansoprazole.
Apalutamide	Apalutamide The serum concentration of Lansoprazole can be increased when it is combined with Apalutamide.
Avatrombopag	Avatrombopag The metabolism of Lansoprazole can be increased when combined with Avatrombopag.
Baricitinib	Baricitinib The metabolism of Baricitinib can be increased when combined with Lansoprazole.
Lofexidine	Lofexidine The metabolism of Lofexidine can be decreased when combined with Lansoprazole.
Eliglustat	Eliglustat The metabolism of Eliglustat can be decreased when combined with Lansoprazole.
Encorafenib	Encorafenib The metabolism of Encorafenib can be decreased when combined with Lansoprazole.
Ivosidenib	Ivosidenib The metabolism of Ivosidenib can be increased when combined with Lansoprazole.
Lusutrombopag	Lusutrombopag Lansoprazole may decrease the excretion rate of Lusutrombopag which could result in a higher serum level.
Elagolix	Elagolix The metabolism of Elagolix can be decreased when combined with Lansoprazole.
Tafenoquine	Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Lansoprazole.
Cannabidiol	Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Lansoprazole.
Dacomitinib	Dacomitinib Lansoprazole can cause a decrease in the absorption of Dacomitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Duvelisib	Duvelisib Lansoprazole may decrease the excretion rate of Duvelisib which could result in a higher serum level.
Stiripentol	Stiripentol The metabolism of Lansoprazole can be decreased when combined with Stiripentol.
Talazoparib	Talazoparib Lansoprazole may decrease the excretion rate of Talazoparib which could result in a higher serum level.
Gilteritinib	Gilteritinib The metabolism of Gilteritinib can be increased when combined with Lansoprazole.
Glasdegib	Glasdegib Lansoprazole may decrease the excretion rate of Glasdegib which could result in a higher serum level.
Lorlatinib	Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Lansoprazole.
Paclitaxel (with albumin) Injection	Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Lansoprazole.
Rifamycin	Rifamycin The metabolism of Rifamycin can be increased when combined with Lansoprazole.
Prucalopride	Prucalopride The metabolism of Prucalopride can be decreased when combined with Lansoprazole.
Emapalumab-lzsg Injection	Emapalumab-lzsg Injection The metabolism of Lansoprazole can be increased when combined with Emapalumab.
Siponimod	Siponimod The metabolism of Siponimod can be increased when combined with Lansoprazole.
Acyclovir Ophthalmic	Acyclovir Ophthalmic The excretion of Acyclovir can be decreased when combined with Lansoprazole.
Erdafitinib	Erdafitinib The metabolism of Erdafitinib can be increased when combined with Lansoprazole.
Esomeprazole Injection	Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Lansoprazole.
Alpelisib	Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Lansoprazole.
Cladribine	Cladribine Lansoprazole may decrease the excretion rate of Cladribine which could result in a higher serum level.
Darolutamide	Darolutamide Lansoprazole may decrease the excretion rate of Darolutamide which could result in a higher serum level.
Triclabendazole	Triclabendazole The metabolism of Lansoprazole can be decreased when combined with Triclabendazole.
Entrectinib	Entrectinib The metabolism of Entrectinib can be increased when combined with Lansoprazole.
Pexidartinib	Pexidartinib The serum concentration of Pexidartinib can be decreased when it is combined with Lansoprazole.
Istradefylline	Istradefylline The metabolism of Istradefylline can be decreased when combined with Lansoprazole.
Pitolisant	Pitolisant The serum concentration of Lansoprazole can be decreased when it is combined with Pitolisant.
Fedratinib	Fedratinib The metabolism of Fedratinib can be decreased when combined with Lansoprazole.
Lefamulin	Lefamulin The metabolism of Lefamulin can be decreased when combined with Lansoprazole.
Phenytoin Injection	Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Lansoprazole.
Fosphenytoin Injection	Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Lansoprazole.
Zanubrutinib	Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Lansoprazole.
Voxelotor	Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Lansoprazole.
Avapritinib	Avapritinib The metabolism of Avapritinib can be decreased when combined with Lansoprazole.
Lumateperone	Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Lansoprazole.
Ubrogepant	Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Lansoprazole.
Tazemetostat	Tazemetostat Lansoprazole may decrease the excretion rate of Tazemetostat which could result in a higher serum level.
Cenobamate	Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Lansoprazole.
Ozanimod	Ozanimod Lansoprazole may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib	Selumetinib The metabolism of Selumetinib can be decreased when combined with Lansoprazole.
Rimegepant	Rimegepant The metabolism of Rimegepant can be increased when combined with Lansoprazole.
Tucatinib	Tucatinib The metabolism of Tucatinib can be decreased when combined with Lansoprazole.
Ripretinib	Ripretinib Lansoprazole may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Selpercatinib	Selpercatinib The serum concentration of Lansoprazole can be decreased when it is combined with Selpercatinib.
Capmatinib	Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Lansoprazole.
Lemborexant	Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Lansoprazole.
Fostemsavir	Fostemsavir Lansoprazole may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Octreotide	Octreotide Lansoprazole can cause a decrease in the absorption of Octreotide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pralsetinib	Pralsetinib Lansoprazole may decrease the excretion rate of Pralsetinib which could result in a higher serum level.
Opicapone	Opicapone The metabolism of Lansoprazole can be decreased when combined with Opicapone.
Satralizumab-mwge Injection	Satralizumab-mwge Injection The serum concentration of Lansoprazole can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives	Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Lansoprazole.
Theophylline	Theophylline Lansoprazole may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Indomethacin	Indomethacin The excretion of Indomethacin can be decreased when combined with Lansoprazole.
Mefenamic Acid	Mefenamic Acid The metabolism of Lansoprazole can be decreased when combined with Mefenamic acid.
Naproxen	Naproxen The metabolism of Naproxen can be decreased when combined with Lansoprazole.
Trazodone	Trazodone The metabolism of Trazodone can be decreased when combined with Lansoprazole.
Floxuridine	Floxuridine The metabolism of Lansoprazole can be decreased when combined with Floxuridine.
Phenobarbital	Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Lansoprazole.
Methotrexate Injection	Methotrexate Injection The serum concentration of Methotrexate can be increased when it is combined with Lansoprazole.
Primidone	Primidone The metabolism of Primidone can be decreased when combined with Lansoprazole.
Methsuximide	Methsuximide The metabolism of Methsuximide can be decreased when combined with Lansoprazole.
Chlorpromazine	Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Lansoprazole.
Diazepam	Diazepam The metabolism of Diazepam can be decreased when combined with Lansoprazole.
Lorazepam	Lorazepam The metabolism of Lorazepam can be increased when combined with Lansoprazole.
Codeine	Codeine The metabolism of Codeine can be decreased when combined with Lansoprazole.
Tranylcypromine	Tranylcypromine The metabolism of Lansoprazole can be decreased when combined with Tranylcypromine.
Phenelzine	Phenelzine The metabolism of Lansoprazole can be decreased when combined with Phenelzine.
Tetracycline	Tetracycline The excretion of Tetracycline can be decreased when combined with Lansoprazole.
Prochlorperazine	Prochlorperazine The metabolism of Prochlorperazine can be increased when combined with Lansoprazole.
Thioridazine	Thioridazine The metabolism of Thioridazine can be decreased when combined with Lansoprazole.
Dapsone	Dapsone The metabolism of Dapsone can be decreased when combined with Lansoprazole.
Sulfadiazine	Sulfadiazine The metabolism of Lansoprazole can be decreased when combined with Sulfadiazine.
Oxycodone	Oxycodone The metabolism of Oxycodone can be decreased when combined with Lansoprazole.
Methadone	Methadone The metabolism of Methadone can be decreased when combined with Lansoprazole.
Oxybutynin	Oxybutynin The metabolism of Lansoprazole can be decreased when combined with Oxybutynin.
Benztropine	Benztropine The metabolism of Benzatropine can be decreased when combined with Lansoprazole.
Maprotiline	Maprotiline The metabolism of Maprotiline can be decreased when combined with Lansoprazole.
Ibuprofen	Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Lansoprazole.
Perphenazine	Perphenazine The metabolism of Perphenazine can be decreased when combined with Lansoprazole.
Phentermine	Phentermine The metabolism of Phentermine can be increased when combined with Lansoprazole.
Methylphenidate	Methylphenidate Lansoprazole can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Amoxapine	Amoxapine The metabolism of Amoxapine can be decreased when combined with Lansoprazole.
Sulfasalazine	Sulfasalazine Lansoprazole may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Hydrocortisone	Hydrocortisone The excretion of Hydrocortisone can be decreased when combined with Lansoprazole.
Doxorubicin	Doxorubicin The metabolism of Doxorubicin can be increased when combined with Lansoprazole.
Dactinomycin	Dactinomycin Lansoprazole may decrease the excretion rate of Dactinomycin which could result in a higher serum level.
Carbamazepine	Carbamazepine The metabolism of Carbamazepine can be increased when combined with Lansoprazole.
Clonidine	Clonidine The metabolism of Clonidine can be increased when combined with Lansoprazole.
Prazosin	Prazosin Lansoprazole may decrease the excretion rate of Prazosin which could result in a higher serum level.
Cimetidine	Cimetidine The excretion of Cimetidine can be decreased when combined with Lansoprazole.
Warfarin	Warfarin The therapeutic efficacy of Warfarin can be increased when used in combination with Lansoprazole.
Clonazepam	Clonazepam The metabolism of Clonazepam can be increased when combined with Lansoprazole.
Loperamide	Loperamide The metabolism of Loperamide can be decreased when combined with Lansoprazole.
Promethazine	Promethazine The metabolism of Lansoprazole can be decreased when combined with Promethazine.
Daunorubicin	Daunorubicin Lansoprazole may decrease the excretion rate of Daunorubicin which could result in a higher serum level.
Nitrofurantoin	Nitrofurantoin Lansoprazole may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin	Griseofulvin The metabolism of Lansoprazole can be increased when combined with Griseofulvin.
Methenamine	Methenamine The therapeutic efficacy of Methenamine can be decreased when used in combination with Lansoprazole.
Digoxin	Digoxin The serum concentration of Digoxin can be increased when it is combined with Lansoprazole.
Chloroquine	Chloroquine The metabolism of Chloroquine can be decreased when combined with Lansoprazole.
Quinine	Quinine The metabolism of Quinine can be decreased when combined with Lansoprazole.
Sulfinpyrazone	Sulfinpyrazone The metabolism of Lansoprazole can be decreased when combined with Sulfinpyrazone.
Isosorbide	Isosorbide The metabolism of Isosorbide can be increased when combined with Lansoprazole.
Clindamycin Injection	Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Lansoprazole.
Secobarbital	Secobarbital The metabolism of Lansoprazole can be increased when combined with Secobarbital.
Desipramine	Desipramine The metabolism of Desipramine can be decreased when combined with Lansoprazole.
Amitriptyline	Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Lansoprazole.
Imipramine	Imipramine The metabolism of Imipramine can be decreased when combined with Lansoprazole.
Probenecid	Probenecid The metabolism of Lansoprazole can be decreased when combined with Probenecid.
Quinidine	Quinidine The metabolism of Quinidine can be increased when combined with Lansoprazole.
Procainamide	Procainamide The metabolism of Procainamide can be decreased when combined with Lansoprazole.
Isoniazid	Isoniazid The metabolism of Lansoprazole can be decreased when combined with Isoniazid.
Rifampin	Rifampin Lansoprazole can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Valproic Acid	Valproic Acid The metabolism of Valproic acid can be decreased when combined with Lansoprazole.
Tamoxifen	Tamoxifen The metabolism of Tamoxifen can be increased when combined with Lansoprazole.
Levothyroxine	Levothyroxine Lansoprazole can cause a decrease in the absorption of Levothyroxine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Methimazole	Methimazole The metabolism of Lansoprazole can be decreased when combined with Methimazole.
Chlorpropamide	Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Lansoprazole.
Tolbutamide	Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Lansoprazole.
Tolazamide	Tolazamide The metabolism of Tolazamide can be decreased when combined with Lansoprazole.
Dextromethorphan	Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Lansoprazole.
Dinoprostone	Dinoprostone The excretion of Dinoprostone can be decreased when combined with Lansoprazole.
Chlorpheniramine	Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Lansoprazole.
Meclizine	Meclizine The metabolism of Meclizine can be decreased when combined with Lansoprazole.
Hydrochlorothiazide	Hydrochlorothiazide The excretion of Hydrochlorothiazide can be decreased when combined with Lansoprazole.
Chlorzoxazone	Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Lansoprazole.
Carisoprodol	Carisoprodol The metabolism of Carisoprodol can be decreased when combined with Lansoprazole.
Folic Acid	Folic Acid Lansoprazole may decrease the excretion rate of Folic acid which could result in a higher serum level.
Propranolol (Cardiovascular)	Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Lansoprazole.
Nortriptyline	Nortriptyline The metabolism of Nortriptyline can be increased when combined with Lansoprazole.
Spironolactone	Spironolactone The metabolism of Lansoprazole can be decreased when combined with Spironolactone.
Mercaptopurine	Mercaptopurine The excretion of Mercaptopurine can be decreased when combined with Lansoprazole.
Nadolol	Nadolol The metabolism of Nadolol can be decreased when combined with Lansoprazole.
Allopurinol	Allopurinol Lansoprazole may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Fluorouracil Injection	Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Lansoprazole.
Colchicine	Colchicine The metabolism of Colchicine can be decreased when combined with Lansoprazole.
Cefaclor	Cefaclor The excretion of Cefaclor can be decreased when combined with Lansoprazole.
Cefazolin Injection	Cefazolin Injection The excretion of Cefazolin can be decreased when combined with Lansoprazole.
Cephalexin	Cephalexin The excretion of Cephalexin can be decreased when combined with Lansoprazole.
Iron Supplements	Iron Supplements Lansoprazole can cause a decrease in the absorption of Iron resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ketoconazole	Ketoconazole Ketoconazole can cause a decrease in the absorption of Lansoprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Thiotepa Injection	Thiotepa Injection The metabolism of Thiotepa can be increased when combined with Lansoprazole.
Vincristine Injection	Vincristine Injection The metabolism of Vincristine can be increased when combined with Lansoprazole.
Captopril	Captopril Lansoprazole can cause a decrease in the absorption of Captopril resulting in a reduced serum concentration and potentially a decrease in efficacy.
Vinblastine	Vinblastine The metabolism of Vinblastine can be increased when combined with Lansoprazole.
Metoprolol	Metoprolol The metabolism of Metoprolol can be increased when combined with Lansoprazole.
Aspirin	Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Lansoprazole.
Alprazolam	Alprazolam The metabolism of Alprazolam can be decreased when combined with Lansoprazole.
Trimethoprim	Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Lansoprazole.
Diltiazem	Diltiazem The metabolism of Lansoprazole can be decreased when combined with Diltiazem.
Nifedipine	Nifedipine The metabolism of Lansoprazole can be decreased when combined with Nifedipine.
Timolol	Timolol The metabolism of Timolol can be decreased when combined with Lansoprazole.
Verapamil	Verapamil The metabolism of Verapamil can be decreased when combined with Lansoprazole.
Atenolol	Atenolol The metabolism of Atenolol can be decreased when combined with Lansoprazole.
Pindolol	Pindolol The metabolism of Pindolol can be decreased when combined with Lansoprazole.
Cisplatin Injection	Cisplatin Injection The metabolism of Lansoprazole can be decreased when combined with Cisplatin.
Piroxicam	Piroxicam The metabolism of Lansoprazole can be decreased when combined with Piroxicam.
Bumetanide	Bumetanide The excretion of Bumetanide can be decreased when combined with Lansoprazole.
Etoposide	Etoposide The metabolism of Etoposide can be increased when combined with Lansoprazole.
Glyburide	Glyburide The metabolism of Lansoprazole can be decreased when combined with Glyburide.
Glipizide	Glipizide The metabolism of Glipizide can be decreased when combined with Lansoprazole.
Pentamidine Injection	Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Lansoprazole.
Labetalol	Labetalol The metabolism of Labetalol can be decreased when combined with Lansoprazole.
Gemfibrozil	Gemfibrozil The metabolism of Lansoprazole can be decreased when combined with Gemfibrozil.
Ketoprofen	Ketoprofen The metabolism of Ketoprofen can be decreased when combined with Lansoprazole.
Pimozide	Pimozide The metabolism of Pimozide can be increased when combined with Lansoprazole.
Flurbiprofen	Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Lansoprazole.
Amiodarone	Amiodarone The metabolism of Amiodarone can be increased when combined with Lansoprazole.
Buspirone	Buspirone The metabolism of Buspirone can be decreased when combined with Lansoprazole.
Lovastatin	Lovastatin The metabolism of Lovastatin can be decreased when combined with Lansoprazole.
Mesalamine	Mesalamine Lansoprazole can cause a decrease in the absorption of Mesalazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Diclofenac	Diclofenac The metabolism of Diclofenac can be decreased when combined with Lansoprazole.
Fluoxetine	Fluoxetine The metabolism of Fluoxetine can be decreased when combined with Lansoprazole.
Clozapine	Clozapine The metabolism of Lansoprazole can be decreased when combined with Clozapine.
Idarubicin	Idarubicin The metabolism of Idarubicin can be decreased when combined with Lansoprazole.
Etodolac	Etodolac The metabolism of Etodolac can be decreased when combined with Lansoprazole.
Felodipine	Felodipine The metabolism of Lansoprazole can be decreased when combined with Felodipine.
Nabumetone	Nabumetone The metabolism of Nabumetone can be decreased when combined with Lansoprazole.
Pravastatin	Pravastatin The excretion of Pravastatin can be decreased when combined with Lansoprazole.
Quinapril	Quinapril The excretion of Quinapril can be decreased when combined with Lansoprazole.
Simvastatin	Simvastatin The metabolism of Lansoprazole can be decreased when combined with Simvastatin.
Amlodipine	Amlodipine The metabolism of Amlodipine can be increased when combined with Lansoprazole.
Teniposide Injection	Teniposide Injection The metabolism of Teniposide can be increased when combined with Lansoprazole.
Itraconazole	Itraconazole Itraconazole can cause a decrease in the absorption of Lansoprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Atovaquone	Atovaquone The metabolism of Lansoprazole can be decreased when combined with Atovaquone.
Rifabutin	Rifabutin The metabolism of Lansoprazole can be increased when combined with Rifabutin.
Sotalol	Sotalol The metabolism of Sotalol can be decreased when combined with Lansoprazole.
Zolpidem	Zolpidem The metabolism of Zolpidem can be increased when combined with Lansoprazole.
Doxazosin	Doxazosin The metabolism of Doxazosin can be decreased when combined with Lansoprazole.
Omeprazole	Omeprazole The metabolism of Omeprazole can be decreased when combined with Lansoprazole.
Cisapride	Cisapride The metabolism of Cisapride can be increased when combined with Lansoprazole.
Fluvastatin	Fluvastatin The metabolism of Lansoprazole can be decreased when combined with Fluvastatin.
Venlafaxine	Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Lansoprazole.
Famciclovir	Famciclovir The metabolism of Famciclovir can be increased when combined with Lansoprazole.
Fluvoxamine	Fluvoxamine The metabolism of Lansoprazole can be decreased when combined with Fluvoxamine.
Nefazodone	Nefazodone The metabolism of Nefazodone can be decreased when combined with Lansoprazole.
Losartan	Losartan The metabolism of Losartan can be decreased when combined with Lansoprazole.
Valacyclovir	Valacyclovir The excretion of Valaciclovir can be decreased when combined with Lansoprazole.
Tramadol	Tramadol The metabolism of Tramadol can be decreased when combined with Lansoprazole.
Vinorelbine Injection	Vinorelbine Injection The metabolism of Vinorelbine can be increased when combined with Lansoprazole.
Alprostadil Urogenital	Alprostadil Urogenital The excretion of Alprostadil can be decreased when combined with Lansoprazole.
Ifosfamide Injection	Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Lansoprazole.
Nicardipine	Nicardipine The metabolism of Lansoprazole can be decreased when combined with Nicardipine.
Bupropion	Bupropion The metabolism of Bupropion can be decreased when combined with Lansoprazole.
Ticlopidine	Ticlopidine The metabolism of Lansoprazole can be decreased when combined with Ticlopidine.
Saquinavir	Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Lansoprazole.
Lamivudine	Lamivudine Lansoprazole may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole	Riluzole Lansoprazole may decrease the excretion rate of Riluzole which could result in a higher serum level.
Glimepiride	Glimepiride The metabolism of Glimepiride can be decreased when combined with Lansoprazole.
Anastrozole	Anastrozole The metabolism of Anastrozole can be decreased when combined with Lansoprazole.
Indinavir	Indinavir Lansoprazole can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ritonavir	Ritonavir The serum concentration of Lansoprazole can be increased when it is combined with Ritonavir.
Docetaxel Injection	Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Lansoprazole.
Clomipramine	Clomipramine The metabolism of Clomipramine can be increased when combined with Lansoprazole.
Zafirlukast	Zafirlukast The metabolism of Lansoprazole can be decreased when combined with Zafirlukast.
Mirtazapine	Mirtazapine The metabolism of Mirtazapine can be decreased when combined with Lansoprazole.
Topiramate	Topiramate The metabolism of Lansoprazole can be decreased when combined with Topiramate.
Zileuton	Zileuton The metabolism of Zileuton can be decreased when combined with Lansoprazole.
Valsartan	Valsartan The metabolism of Lansoprazole can be decreased when combined with Valsartan.
Donepezil	Donepezil Lansoprazole may decrease the excretion rate of Donepezil which could result in a higher serum level.
Nelfinavir	Nelfinavir The serum concentration of Nelfinavir can be decreased when it is combined with Lansoprazole.
Fexofenadine	Fexofenadine The excretion of Fexofenadine can be decreased when combined with Lansoprazole.
Azithromycin	Azithromycin The metabolism of Azithromycin can be increased when combined with Lansoprazole.
Loratadine	Loratadine The metabolism of Lansoprazole can be decreased when combined with Loratadine.
Carvedilol	Carvedilol The metabolism of Carvedilol can be decreased when combined with Lansoprazole.
Nilutamide	Nilutamide The metabolism of Lansoprazole can be decreased when combined with Nilutamide.
Selegiline	Selegiline The metabolism of Selegiline can be decreased when combined with Lansoprazole.
Bicalutamide	Bicalutamide The metabolism of Lansoprazole can be increased when combined with Bicalutamide.
Sertraline	Sertraline The metabolism of Lansoprazole can be decreased when combined with Sertraline.
Propafenone	Propafenone The metabolism of Propafenone can be decreased when combined with Lansoprazole.
Letrozole	Letrozole The metabolism of Lansoprazole can be decreased when combined with Letrozole.
Raloxifene	Raloxifene Lansoprazole may decrease the excretion rate of Raloxifene which could result in a higher serum level.
Irbesartan	Irbesartan The metabolism of Lansoprazole can be decreased when combined with Irbesartan.
Tamsulosin	Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Lansoprazole.
Quetiapine	Quetiapine The metabolism of Quetiapine can be decreased when combined with Lansoprazole.
Paroxetine	Paroxetine The metabolism of Lansoprazole can be decreased when combined with Paroxetine.
Tolcapone	Tolcapone The metabolism of Lansoprazole can be decreased when combined with Tolcapone.
Citalopram	Citalopram The serum concentration of Citalopram can be increased when it is combined with Lansoprazole.
Capecitabine	Capecitabine The metabolism of Lansoprazole can be decreased when combined with Capecitabine.
Efavirenz	Efavirenz The metabolism of Lansoprazole can be decreased when combined with Efavirenz.
Sildenafil	Sildenafil The metabolism of Sildenafil can be decreased when combined with Lansoprazole.
Pioglitazone	Pioglitazone The metabolism of Lansoprazole can be decreased when combined with Pioglitazone.
Celecoxib	Celecoxib Lansoprazole may decrease the excretion rate of Celecoxib which could result in a higher serum level.
Rosiglitazone	Rosiglitazone The metabolism of Lansoprazole can be decreased when combined with Rosiglitazone.
Tolterodine	Tolterodine The metabolism of Tolterodine can be decreased when combined with Lansoprazole.
Thalidomide	Thalidomide The metabolism of Lansoprazole can be decreased when combined with Thalidomide.
Oseltamivir	Oseltamivir The excretion of Oseltamivir can be decreased when combined with Lansoprazole.
Nateglinide	Nateglinide The metabolism of Nateglinide can be decreased when combined with Lansoprazole.
Galantamine	Galantamine The metabolism of Galantamine can be decreased when combined with Lansoprazole.
Rabeprazole	Rabeprazole The metabolism of Rabeprazole can be decreased when combined with Lansoprazole.
Terbinafine	Terbinafine The metabolism of Terbinafine can be decreased when combined with Lansoprazole.