Lansoprazole

Generic name: Pronounced as (lan soe' pra zole)
Brand names
  • Prevacid®
  • Prevacid® 24HR
  • Prevacid® SoluTab®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 01/15/2022

Prescription lansoprazole is used to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube between the throat and stomach) in adults and children 1 year of age and older. Prescription lansoprazole is used to treat the damage from GERD in adults and children 1 year of age and older. Prescription lansoprazole is used to allow the esophagus to heal and prevent further damage to the esophagus in adults with GERD. Prescription lansoprazole is also used to treat ulcers (sores in the lining of the stomach or intestine), to prevent more ulcers from developing in adults whose ulcers have already healed, and to decrease the risk that adults who are taking nonsteroidal anti-inflammatory drugs (NSAIDs) will develop ulcers. Prescription lansoprazole is also used to treat conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome in adults. Prescription lansoprazole is also used in combination with other medications to treat and prevent stomach ulcers caused by a certain type of bacteria (H. pylori) in adults. Nonprescription (over-the-counter) lansoprazole is used to treat frequent heartburn (heartburn that occurs two or more days per week) in adults. Lansoprazole is in a class of medications called proton pump inhibitors. It works by decreasing the amount of acid made in the stomach.

Prescription lansoprazole comes as a delayed-release (releases the medication in the intestine to prevent break-down of the medication by stomach acids) capsule and as a delayed-release orally disintegrating (dissolving) tablet to take by mouth. Nonprescription lansoprazole comes as a delayed-release capsule to take by mouth. Prescription lansoprazole is usually taken once a day, before a meal. When taken in combination with other medications to eliminate H. pylori, prescription lansoprazole is taken twice a day (every 12 hours) or three times a day (every 8 hours), before a meal, for 10 to 14 days. Nonprescription lansoprazole is usually taken once a day, in the morning before eating for 14 days. If needed, additional 14-day treatments may be repeated, not more often than once every 4 months. Take lansoprazole at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lansoprazole exactly as directed. Do not take more or less of it or take it more often or for a longer time than prescribed by your doctor or stated on the package. Tell your doctor if you have taken nonprescription lansoprazole for a longer period of time than stated on the package.

Swallow the prescription capsules whole; do not split, chew, or crush them. If you have difficulty swallowing capsules, you may open the capsule, sprinkle the granules on 1 tablespoon of applesauce, Ensure® pudding, cottage cheese, yogurt, or strained pears and swallow the mixture immediately without chewing. You can also open a capsule and pour the contents into 2 ounces (60 milliliters) of orange juice, apple juice or tomato juice, mix briefly, and swallow immediately. After you swallow the mixture, rinse the glass with some additional juice and drink immediately. Then rinse the glass with juice at least two more times and drink the juice to be sure that you wash all the medication out of the glass.

Swallow the nonprescription capsules whole with a glass of water. Do not split, chew, or crush them.

Do not break, cut or chew the orally disintegrating tablets. Place a tablet on your tongue and wait up to one minute for it to dissolve. After the tablet dissolves, swallow it with or without water. If you cannot swallow the tablet, you may place it in an oral syringe, draw up 4 mL of water for a 15 mg tablet or 10 mL of water for a 30-mg tablet, shake the syringe gently to dissolve the tablet, and squirt the contents into your mouth immediately. Then draw an additional 2 mL of water into the syringe, shake gently, and squirt that water into your mouth. Do not swallow the mixture more than 15 minutes after you dissolve the tablet.

The capsule contents and orally disintegrating tablets can both be given through a feeding tube. If you have a feeding tube, ask your doctor how you should take the medication. Follow these directions carefully.

Do not take nonprescription lansoprazole for immediate relief of heartburn symptoms. It may take 1 to 4 days for you to feel the full benefit of the medication. Call your doctor if your symptoms get worse or do not improve after 14 days or if your symptoms return sooner than 4 months after you finish your treatment. Do not take nonprescription lansoprazole for longer than 14 days or treat yourself with lansoprazole more often than once every 4 months without talking to your doctor.

Continue to take lansoprazole even if you feel well. Do not stop taking prescription lansoprazole without talking to your doctor. If your condition does not improve or gets worse, call your doctor.

Ask your doctor or pharmacist for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking lansoprazole,

  • tell your doctor and pharmacist if you are allergic to lansoprazole, any other medications, or any of the ingredients in lansoprazole capsules or orally disintegrating tablets. Ask your doctor or pharmacist for a list of the ingredients.

  • tell your doctor if you are taking rilpivirine (Edurant, in Cabenuva, Complera, Juluca, Odefsey). Your doctor will probably tell you not to take lansoprazole if you are taking this medication.

  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: certain antibiotics, including anticoagulants (blood thinners) such as warfarin (Jantoven), atazanavir (Reyataz, in Evotaz), dasatinib (Sprycel), digoxin (Lanoxin), diuretics ('water pills'), erlotinib (Tarceva), iron supplements, itraconazole (Sporonox, Tolsura), ketoconazole, methotrexate (Trexall, Xatmep), mycophenolate mofetil (Cellcept, Myfortic), nelfinavir (Viracept), nilotinib (Tasigna), rifampin (Rifadin, Rimactane), ritonavir (Norvir, in Kaletra), saquinavir (Invirase), tacrolimus (Astagraf, Envarsus, Prograf), theophylline (Theo-24), and voriconazole (Vfend). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor what herbal products you are taking, especially St. John's wort. Your doctor may tell you not to take St. John's wort while taking lansoprazole.

  • if you are taking sucralfate (Carafate), take it at least 30 minutes after you take lansoprazole.

  • tell your doctor if you have or have ever had a low level of magnesium, calcium, potassium, or sodium in your blood; hypoparathyroidism (condition in which the body does not produce enough parathyroid hormone [PTH; a natural substance needed to control the amount of calcium in the blood]); low levels of vitamin B12 in your body; osteoporosis (a condition in which the bones become thin and weak and break easily); an autoimmune disease (condition in which the body attacks its own organs, causing swelling and loss of function) such as systemic lupus erythematosus; or liver disease.

  • if you plan to take nonprescription lansoprazole, first tell your doctor if your heartburn has lasted 3 months or longer or if you have experienced any of the following symptoms: lightheadedness, sweating, or dizziness along with your heartburn; chest pain or shoulder pain; shortness of breath or wheezing; pain that spreads to your arms, neck, or shoulders; unexplained weight loss; nausea; vomiting, especially if the vomit is bloody; stomach pain; difficulty swallowing food or pain when you swallow food; or black or bloody stools. You may have a more serious condition that cannot be treated with a nonprescription medication.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking lansoprazole, call your doctor.

  • if you are 70 years of age or older, do not take this medication for a longer period of time than recommended on the product label or by your doctor.

  • if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent damage to your brain that can cause severe intellectual disability), you should know that the orally disintegrating tablets may contain aspartame, which forms phenylalanine.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your dosing schedule. Do not take a double dose to make up for a missed one.

  • Lansoprazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • constipation

    • nausea

    • headache

    • dizziness

    • diarrhea

  • Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

    • rash; hives; itching; swelling of the eyes, face, lips, mouth, throat, or tongue; difficulty breathing or swallowing; hoarseness

    • blistering, peeling, or bleeding skin; sores on the lips, nose, mouth, or genitals; swollen glands; shortness of breath; fever; flu-like symptoms

    • increased or decreased urination, blood in urine, fatigue, nausea, loss of appetite, fever, rash, or joint pain

    • irregular, fast, or pounding heartbeat; muscle spasms; uncontrollable shaking of a part of the body; excessive tiredness; lightheadedness; dizziness; or seizures

    • severe diarrhea with watery stools, stomach pain, or fever that does not go away

    • new or worsening joint pain; rash on cheeks or arms that is sensitive to sunlight

  • Lansoprazole may cause other side effects. Call your doctor if you have any unusual problems while you are taking the medication.

  • People who take proton pump inhibitors such as lansoprazole may be more likely to fracture their wrists, hips, or spine than people who do not take one of these medications. People who take proton pump inhibitors may also develop fundic gland polyps (a type of growth on the stomach lining). These risks are highest in people who take high doses of one of these medications or take them for 1 year or longer. Talk to your doctor about the risk of taking lansoprazole.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain laboratory tests before and during your treatment.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking lansoprazole.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • Prevacid® NapraPAC® (containing Lansoprazole, Naproxen)

Drug Interaction
Repaglinide Repaglinide The metabolism of Repaglinide can be decreased when combined with Lansoprazole.
Montelukast Montelukast The metabolism of Lansoprazole can be decreased when combined with Montelukast.
Leflunomide Leflunomide Lansoprazole may decrease the excretion rate of Leflunomide which could result in a higher serum level.
Delavirdine Delavirdine Delavirdine can cause a decrease in the absorption of Lansoprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nevirapine Nevirapine The metabolism of Lansoprazole can be decreased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Lansoprazole.
Dolasetron Dolasetron The metabolism of Dolasetron can be decreased when combined with Lansoprazole.
Alendronate Alendronate The therapeutic efficacy of Alendronic acid can be decreased when used in combination with Lansoprazole.
Aminophylline Aminophylline The metabolism of Aminophylline can be increased when combined with Lansoprazole.
Bisacodyl Bisacodyl The therapeutic efficacy of Bisacodyl can be decreased when used in combination with Lansoprazole.
Candesartan Candesartan The metabolism of Lansoprazole can be decreased when combined with Candesartan.
Cilostazol Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Lansoprazole.
Clopidogrel Clopidogrel The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Lansoprazole resulting in a loss in efficacy.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The excretion of Conjugated estrogens can be decreased when combined with Lansoprazole.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be increased when combined with Lansoprazole.
Mycophenolate Mycophenolate Lansoprazole can cause a decrease in the absorption of Mycophenolic acid resulting in a reduced serum concentration and potentially a decrease in efficacy.
Paregoric Paregoric The metabolism of Lansoprazole can be decreased when combined with Morphine.
Penbutolol Penbutolol The metabolism of Acebutolol can be decreased when combined with Lansoprazole.
Ranitidine Ranitidine The excretion of Ranitidine can be decreased when combined with Lansoprazole.
Sumatriptan Sumatriptan Lansoprazole may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Lansoprazole.
Tiludronate Tiludronate The therapeutic efficacy of Etidronic acid can be decreased when used in combination with Lansoprazole.
Famotidine Injection Famotidine Injection The excretion of Famotidine can be decreased when combined with Lansoprazole.
Fluconazole Injection Fluconazole Injection The metabolism of Lansoprazole can be decreased when combined with Fluconazole.
Hydromorphone Injection Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Lansoprazole.
Meperidine Injection Meperidine Injection The metabolism of Meperidine can be increased when combined with Lansoprazole.
Metoclopramide Injection Metoclopramide Injection The metabolism of Metoclopramide can be decreased when combined with Lansoprazole.
Metronidazole Injection Metronidazole Injection The metabolism of Lansoprazole can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The metabolism of Lansoprazole can be decreased when combined with Morphine.
Zidovudine Injection Zidovudine Injection The excretion of Zidovudine can be decreased when combined with Lansoprazole.
Altretamine Altretamine Lansoprazole can cause an increase in the absorption of Amphetamine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Cefuroxime Cefuroxime The serum concentration of Cefuroxime can be decreased when it is combined with Lansoprazole.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be increased when combined with Lansoprazole.
Ondansetron Ondansetron The metabolism of Ondansetron can be decreased when combined with Lansoprazole.
Torsemide Torsemide The metabolism of Lansoprazole can be decreased when combined with Torasemide.
Olanzapine Olanzapine The metabolism of Lansoprazole can be decreased when combined with Olanzapine.
Alosetron Alosetron The metabolism of Alosetron can be decreased when combined with Lansoprazole.
Dofetilide Dofetilide The metabolism of Dofetilide can be increased when combined with Lansoprazole.
Hydroxychloroquine Hydroxychloroquine The metabolism of Hydroxychloroquine can be decreased when combined with Lansoprazole.
Meloxicam Meloxicam The metabolism of Meloxicam can be decreased when combined with Lansoprazole.
Oxcarbazepine Oxcarbazepine The metabolism of Lansoprazole can be decreased when combined with Oxcarbazepine.
Pantoprazole Pantoprazole The metabolism of Pantoprazole can be decreased when combined with Lansoprazole.
Risedronate Risedronate Lansoprazole can cause an increase in the absorption of Risedronic acid resulting in an increased serum concentration and potentially a worsening of adverse effects.
Telmisartan Telmisartan The metabolism of Lansoprazole can be decreased when combined with Telmisartan.
Anakinra Anakinra The metabolism of Lansoprazole can be increased when combined with Anakinra.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Lansoprazole.
Etanercept Injection Etanercept Injection The metabolism of Lansoprazole can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Lansoprazole can be decreased when combined with Modafinil.
Tenofovir Tenofovir The metabolism of Tenofovir can be increased when combined with Lansoprazole.
Sirolimus Sirolimus The metabolism of Sirolimus can be increased when combined with Lansoprazole.
Epinephrine Injection Epinephrine Injection The metabolism of Lansoprazole can be decreased when combined with Epinephrine.
Escitalopram Escitalopram The metabolism of Escitalopram can be decreased when combined with Lansoprazole.
Zonisamide Zonisamide The metabolism of Zonisamide can be decreased when combined with Lansoprazole.
Adalimumab Injection Adalimumab Injection The metabolism of Lansoprazole can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be increased when combined with Lansoprazole.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Lansoprazole.
Dexmethylphenidate Dexmethylphenidate Lansoprazole can cause an increase in the absorption of Dexmethylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Ezetimibe Ezetimibe Lansoprazole may decrease the excretion rate of Ezetimibe which could result in a higher serum level.
Atazanavir Atazanavir The therapeutic efficacy of Atazanavir can be decreased when used in combination with Lansoprazole.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Lansoprazole.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Lansoprazole.
Rosuvastatin Rosuvastatin Lansoprazole may decrease the excretion rate of Rosuvastatin which could result in a higher serum level.
Vardenafil Vardenafil The metabolism of Vardenafil can be decreased when combined with Lansoprazole.
Alfuzosin Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Lansoprazole.
Aprepitant Aprepitant The metabolism of Lansoprazole can be decreased when combined with Aprepitant.
Memantine Memantine Memantine may decrease the excretion rate of Lansoprazole which could result in a higher serum level.
Tegaserod Tegaserod Lansoprazole may decrease the excretion rate of Tegaserod which could result in a higher serum level.
Fosamprenavir Fosamprenavir Lansoprazole can cause a decrease in the absorption of Fosamprenavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Progesterone Progesterone The metabolism of Progesterone can be decreased when combined with Lansoprazole.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Lansoprazole.
Infliximab Injection Infliximab Injection The metabolism of Lansoprazole can be increased when combined with Infliximab.
Oxandrolone Oxandrolone The metabolism of Lansoprazole can be decreased when combined with Oxandrolone.
Protriptyline Protriptyline The metabolism of Protriptyline can be decreased when combined with Lansoprazole.
Rifaximin Rifaximin The metabolism of Lansoprazole can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Duloxetine can be increased when combined with Lansoprazole.
Norethindrone Norethindrone The metabolism of Norethisterone can be increased when combined with Lansoprazole.
Bosentan Bosentan The metabolism of Bosentan can be decreased when combined with Lansoprazole.
Cefditoren Cefditoren The excretion of Cefdinir can be decreased when combined with Lansoprazole.
Erlotinib Erlotinib Lansoprazole can cause a decrease in the absorption of Erlotinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Eszopiclone Eszopiclone The serum concentration of Eszopiclone can be decreased when it is combined with Lansoprazole.
Solifenacin Solifenacin The metabolism of Solifenacin can be decreased when combined with Lansoprazole.
Voriconazole Voriconazole The metabolism of Lansoprazole can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine Lansoprazole can cause an increase in the absorption of Amphetamine resulting in an increased serum concentration and potentially a worsening of adverse effects.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The metabolism of Lansoprazole can be increased when combined with Peginterferon alfa-2b.
Ibandronate Ibandronate The therapeutic efficacy of Ibandronate can be decreased when used in combination with Lansoprazole.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Lansoprazole.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Lansoprazole.
Fentanyl Fentanyl The metabolism of Fentanyl can be decreased when combined with Lansoprazole.
Deferasirox Deferasirox The metabolism of Lansoprazole can be decreased when combined with Deferasirox.
Tipranavir Tipranavir The metabolism of Lansoprazole can be decreased when combined with Tipranavir.
Felbamate Felbamate The metabolism of Lansoprazole can be decreased when combined with Felbamate.
Ranolazine Ranolazine The metabolism of Lansoprazole can be increased when combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Lansoprazole can be increased when combined with Abatacept.
Imatinib Imatinib Lansoprazole may increase the dermatologic adverse activities of Imatinib.
Sitagliptin Sitagliptin The excretion of Sitagliptin can be decreased when combined with Lansoprazole.
Gefitinib Gefitinib Lansoprazole can cause a decrease in the absorption of Gefitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Paliperidone Paliperidone The metabolism of Paliperidone can be decreased when combined with Lansoprazole.
Bortezomib Bortezomib The metabolism of Lansoprazole can be increased when combined with Bortezomib.
Clofarabine Injection Clofarabine Injection The excretion of Clofarabine can be decreased when combined with Lansoprazole.
Oxaliplatin Injection Oxaliplatin Injection Lansoprazole may decrease the excretion rate of Oxaliplatin which could result in a higher serum level.
Posaconazole Posaconazole Lansoprazole can cause a decrease in the absorption of Posaconazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Darunavir Darunavir Lansoprazole can cause a decrease in the absorption of Darunavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pemetrexed Injection Pemetrexed Injection The excretion of Pemetrexed can be decreased when combined with Lansoprazole.
Lisdexamfetamine Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Lansoprazole.
Nabilone Nabilone The metabolism of Lansoprazole can be decreased when combined with Nabilone.
Retapamulin Retapamulin The metabolism of Retapamulin can be decreased when combined with Lansoprazole.
Sorafenib Sorafenib The metabolism of Lansoprazole can be increased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Sunitinib can be increased when combined with Lansoprazole.
Dronabinol Dronabinol The metabolism of Dronabinol can be decreased when combined with Lansoprazole.
Lapatinib Lapatinib The metabolism of Lapatinib can be decreased when combined with Lansoprazole.
Dasatinib Dasatinib Lansoprazole can cause a decrease in the absorption of Dasatinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Mexiletine Mexiletine The metabolism of Mexiletine can be decreased when combined with Lansoprazole.
Armodafinil Armodafinil The metabolism of Lansoprazole can be decreased when combined with Armodafinil.
Ivermectin Ivermectin Lansoprazole may decrease the excretion rate of Ivermectin which could result in a higher serum level.
Temsirolimus Temsirolimus The metabolism of Temsirolimus can be increased when combined with Lansoprazole.
Nilotinib Nilotinib The serum concentration of Lansoprazole can be decreased when it is combined with Nilotinib.
Raltegravir Raltegravir Lansoprazole can cause an increase in the absorption of Raltegravir resulting in an increased serum concentration and potentially a worsening of adverse effects.
Bexarotene Bexarotene The metabolism of Lansoprazole can be decreased when combined with Bexarotene.
Budesonide Budesonide Lansoprazole can cause a decrease in the absorption of Budesonide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Lansoprazole can be decreased when combined with Chloramphenicol.
Doripenem Injection Doripenem Injection The excretion of Doripenem can be decreased when combined with Lansoprazole.
Etravirine Etravirine The metabolism of Etravirine can be decreased when combined with Lansoprazole.
Mitoxantrone Injection Mitoxantrone Injection Lansoprazole may decrease the excretion rate of Mitoxantrone which could result in a higher serum level.
Cevimeline Cevimeline The metabolism of Cevimeline can be decreased when combined with Lansoprazole.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Lansoprazole.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Lansoprazole.
Leucovorin Injection Leucovorin Injection The excretion of Leucovorin can be decreased when combined with Lansoprazole.
Flecainide Flecainide The metabolism of Lansoprazole can be decreased when combined with Flecainide.
Certolizumab Injection Certolizumab Injection The metabolism of Lansoprazole can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be increased when combined with Lansoprazole.
Irinotecan Injection Irinotecan Injection The metabolism of Irinotecan can be increased when combined with Lansoprazole.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Lansoprazole.
Rufinamide Rufinamide The metabolism of Rufinamide can be increased when combined with Lansoprazole.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Lansoprazole.
Eltrombopag Eltrombopag The metabolism of Lansoprazole can be decreased when combined with Eltrombopag.
Milnacipran Milnacipran The metabolism of Milnacipran can be increased when combined with Lansoprazole.
Dexlansoprazole Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Lansoprazole.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Lansoprazole.
Betaxolol Betaxolol The metabolism of Betaxolol can be decreased when combined with Lansoprazole.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Lansoprazole.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Lansoprazole.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Lansoprazole.
Everolimus Everolimus The metabolism of Everolimus can be increased when combined with Lansoprazole.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The metabolism of Tolvaptan can be increased when combined with Lansoprazole.
Dronedarone Dronedarone The metabolism of Dronedarone can be increased when combined with Lansoprazole.
Pralatrexate Injection Pralatrexate Injection Lansoprazole may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Lansoprazole.
Saxagliptin Saxagliptin The excretion of Saxagliptin can be decreased when combined with Lansoprazole.
Romidepsin Injection Romidepsin Injection The metabolism of Romidepsin can be increased when combined with Lansoprazole.
Tapentadol Tapentadol The metabolism of Tapentadol can be decreased when combined with Lansoprazole.
Topotecan Topotecan Lansoprazole may decrease the excretion rate of Topotecan which could result in a higher serum level.
Golimumab Injection Golimumab Injection The metabolism of Lansoprazole can be increased when combined with Golimumab.
Pazopanib Pazopanib Lansoprazole can cause a decrease in the absorption of Pazopanib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pitavastatin Pitavastatin Lansoprazole may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole Albendazole The metabolism of Albendazole can be decreased when combined with Lansoprazole.
Ulipristal Ulipristal The metabolism of Ulipristal can be increased when combined with Lansoprazole.
Levonorgestrel Levonorgestrel The metabolism of Levonorgestrel can be increased when combined with Lansoprazole.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Lansoprazole.
Tocilizumab Injection Tocilizumab Injection The metabolism of Lansoprazole can be increased when combined with Tocilizumab.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be increased when combined with Lansoprazole.
Acetaminophen Injection Acetaminophen Injection The metabolism of Acetaminophen can be decreased when combined with Lansoprazole.
Vilazodone Vilazodone The metabolism of Vilazodone can be decreased when combined with Lansoprazole.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be increased when combined with Lansoprazole.
Roflumilast Roflumilast The metabolism of Roflumilast can be increased when combined with Lansoprazole.
Linagliptin Linagliptin The metabolism of Linagliptin can be increased when combined with Lansoprazole.
Rilpivirine Rilpivirine Lansoprazole can cause a decrease in the absorption of Rilpivirine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Telaprevir Telaprevir Lansoprazole may decrease the excretion rate of Glecaprevir which could result in a higher serum level.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be increased when combined with Lansoprazole.
Abiraterone Abiraterone The metabolism of Lansoprazole can be decreased when combined with Abiraterone.
Rivaroxaban Rivaroxaban Lansoprazole may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ticagrelor Ticagrelor The metabolism of Lansoprazole can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Brentuximab vedotin can be increased when combined with Lansoprazole.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be increased when combined with Lansoprazole.
Vandetanib Vandetanib The metabolism of Vandetanib can be increased when combined with Lansoprazole.
Clobazam Clobazam The metabolism of Clobazam can be decreased when combined with Lansoprazole.
Vemurafenib Vemurafenib The metabolism of Vemurafenib can be increased when combined with Lansoprazole.
Vismodegib Vismodegib The metabolism of Vismodegib can be decreased when combined with Lansoprazole.
Axitinib Axitinib The metabolism of Axitinib can be increased when combined with Lansoprazole.
Crizotinib Crizotinib The metabolism of Crizotinib can be increased when combined with Lansoprazole.
Cabergoline Cabergoline The metabolism of Cabergoline can be increased when combined with Lansoprazole.
Enzalutamide Enzalutamide The metabolism of Lansoprazole can be increased when combined with Enzalutamide.
Mirabegron Mirabegron The metabolism of Mirabegron can be decreased when combined with Lansoprazole.
Regorafenib Regorafenib The metabolism of Lansoprazole can be increased when combined with Regorafenib.
Bosutinib Bosutinib Bosutinib can cause a decrease in the absorption of Lansoprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Teriflunomide Teriflunomide Lansoprazole may decrease the excretion rate of Teriflunomide which could result in a higher serum level.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Lansoprazole.
Tofacitinib Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Lansoprazole.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Lansoprazole.
Ponatinib Ponatinib The metabolism of Ponatinib can be increased when combined with Lansoprazole.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be increased when combined with Lansoprazole.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Trastuzumab emtansine can be increased when combined with Lansoprazole.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Lansoprazole.
Dabrafenib Dabrafenib The serum concentration of Lansoprazole can be decreased when it is combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Lansoprazole.
Trametinib Trametinib The metabolism of Lansoprazole can be decreased when combined with Trametinib.
Dolutegravir Dolutegravir Lansoprazole may decrease the excretion rate of Dolutegravir which could result in a higher serum level.
Afatinib Afatinib Lansoprazole may decrease the excretion rate of Afatinib which could result in a higher serum level.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be increased when combined with Lansoprazole.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Lansoprazole.
Perampanel Perampanel The metabolism of Perampanel can be increased when combined with Lansoprazole.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Lansoprazole.
Lomitapide Lomitapide The metabolism of Lomitapide can be increased when combined with Lansoprazole.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Lansoprazole.
Simeprevir Simeprevir Lansoprazole may decrease the excretion rate of Simeprevir which could result in a higher serum level.
Sofosbuvir Sofosbuvir Lansoprazole may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Lansoprazole.
Iron Sucrose Injection Iron Sucrose Injection Lansoprazole can cause a decrease in the absorption of Iron sucrose resulting in a reduced serum concentration and potentially a decrease in efficacy.
Apremilast Apremilast The metabolism of Lansoprazole can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Ceritinib can be increased when combined with Lansoprazole.
Siltuximab Injection Siltuximab Injection The metabolism of Lansoprazole can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The metabolism of Lansoprazole can be decreased when combined with Eslicarbazepine.
Iron Dextran Injection Iron Dextran Injection Lansoprazole can cause a decrease in the absorption of Iron Dextran resulting in a reduced serum concentration and potentially a decrease in efficacy.
Idelalisib Idelalisib The metabolism of Idelalisib can be increased when combined with Lansoprazole.
Testosterone Injection Testosterone Injection The metabolism of Lansoprazole can be decreased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Lansoprazole can be decreased when combined with Oritavancin.
Vorapaxar Vorapaxar The metabolism of Vorapaxar can be increased when combined with Lansoprazole.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Lansoprazole.
Suvorexant Suvorexant The metabolism of Suvorexant can be increased when combined with Lansoprazole.
Olaparib Olaparib The metabolism of Olaparib can be increased when combined with Lansoprazole.
Methamphetamine Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Lansoprazole.
Tasimelteon Tasimelteon The metabolism of Tasimelteon can be increased when combined with Lansoprazole.
Riociguat Riociguat Lansoprazole can cause a decrease in the absorption of Riociguat resulting in a reduced serum concentration and potentially a decrease in efficacy.
Nintedanib Nintedanib The metabolism of Nintedanib can be increased when combined with Lansoprazole.
Secukinumab Injection Secukinumab Injection The metabolism of Lansoprazole can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Risperidone can be decreased when combined with Lansoprazole.
Palbociclib Palbociclib The absorption of Palbociclib can be decreased when combined with Lansoprazole.
Lenvatinib Lenvatinib Lansoprazole may decrease the excretion rate of Lenvatinib which could result in a higher serum level.
Naloxegol Naloxegol The metabolism of Lansoprazole can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Panobinostat can be increased when combined with Lansoprazole.
Haloperidol Injection Haloperidol Injection The serum concentration of Haloperidol can be increased when it is combined with Lansoprazole.
Sonidegib Sonidegib The metabolism of Sonidegib can be increased when combined with Lansoprazole.
Flibanserin Flibanserin The serum concentration of Flibanserin can be increased when it is combined with Lansoprazole.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Lansoprazole.
Ziprasidone Injection Ziprasidone Injection The metabolism of Ziprasidone can be increased when combined with Lansoprazole.
Cariprazine Cariprazine The metabolism of Cariprazine can be decreased when combined with Lansoprazole.
Eluxadoline Eluxadoline The excretion of Eluxadoline can be decreased when combined with Lansoprazole.
Cobimetinib Cobimetinib The metabolism of Cobimetinib can be increased when combined with Lansoprazole.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be increased when combined with Lansoprazole.
Osimertinib Osimertinib The metabolism of Osimertinib can be increased when combined with Lansoprazole.
Alectinib Alectinib The metabolism of Alectinib can be increased when combined with Lansoprazole.
Ixazomib Ixazomib The metabolism of Ixazomib can be increased when combined with Lansoprazole.
Rifapentine Rifapentine The metabolism of Lansoprazole can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Lansoprazole.
Dexamethasone Injection Dexamethasone Injection The excretion of Dexamethasone can be decreased when combined with Lansoprazole.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Lansoprazole.
Venetoclax Venetoclax The metabolism of Venetoclax can be increased when combined with Lansoprazole.
Selexipag Selexipag The metabolism of Selexipag can be decreased when combined with Lansoprazole.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Lansoprazole.
Rucaparib Rucaparib Lansoprazole may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Ribociclib Ribociclib The metabolism of Ribociclib can be increased when combined with Lansoprazole.
Brigatinib Brigatinib The metabolism of Brigatinib can be increased when combined with Lansoprazole.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Lansoprazole.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Lansoprazole.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Lansoprazole.
Safinamide Safinamide The metabolism of Lansoprazole can be decreased when combined with Safinamide.
Edaravone Injection Edaravone Injection The excretion of Edaravone can be decreased when combined with Lansoprazole.
Midostaurin Midostaurin The metabolism of Lansoprazole can be increased when combined with Midostaurin.
Neratinib Neratinib The metabolism of Neratinib can be increased when combined with Lansoprazole.
Enasidenib Enasidenib The metabolism of Enasidenib can be increased when combined with Lansoprazole.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be increased when combined with Lansoprazole.
Copanlisib Injection Copanlisib Injection The metabolism of Copanlisib can be increased when combined with Lansoprazole.
Delafloxacin Delafloxacin Lansoprazole may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be increased when combined with Lansoprazole.
Acalabrutinib Acalabrutinib The metabolism of Acalabrutinib can be increased when combined with Lansoprazole.
Letermovir Letermovir The metabolism of Lansoprazole can be decreased when combined with Letermovir.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Lansoprazole.
Ertugliflozin Ertugliflozin Lansoprazole may decrease the excretion rate of Ertugliflozin which could result in a higher serum level.
Buprenorphine Injection Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Lansoprazole.
Apalutamide Apalutamide The serum concentration of Lansoprazole can be increased when it is combined with Apalutamide.
Avatrombopag Avatrombopag The metabolism of Lansoprazole can be increased when combined with Avatrombopag.
Baricitinib Baricitinib The metabolism of Baricitinib can be increased when combined with Lansoprazole.
Lofexidine Lofexidine The metabolism of Lofexidine can be decreased when combined with Lansoprazole.
Eliglustat Eliglustat The metabolism of Eliglustat can be decreased when combined with Lansoprazole.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Lansoprazole.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be increased when combined with Lansoprazole.
Lusutrombopag Lusutrombopag Lansoprazole may decrease the excretion rate of Lusutrombopag which could result in a higher serum level.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Lansoprazole.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Lansoprazole.
Cannabidiol Cannabidiol The metabolism of Cannabidiol can be decreased when combined with Lansoprazole.
Dacomitinib Dacomitinib Lansoprazole can cause a decrease in the absorption of Dacomitinib resulting in a reduced serum concentration and potentially a decrease in efficacy.
Duvelisib Duvelisib Lansoprazole may decrease the excretion rate of Duvelisib which could result in a higher serum level.
Stiripentol Stiripentol The metabolism of Lansoprazole can be decreased when combined with Stiripentol.
Talazoparib Talazoparib Lansoprazole may decrease the excretion rate of Talazoparib which could result in a higher serum level.
Gilteritinib Gilteritinib The metabolism of Gilteritinib can be increased when combined with Lansoprazole.
Glasdegib Glasdegib Lansoprazole may decrease the excretion rate of Glasdegib which could result in a higher serum level.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Lansoprazole.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be increased when combined with Lansoprazole.
Rifamycin Rifamycin The metabolism of Rifamycin can be increased when combined with Lansoprazole.
Prucalopride Prucalopride The metabolism of Prucalopride can be decreased when combined with Lansoprazole.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Lansoprazole can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be increased when combined with Lansoprazole.
Acyclovir Ophthalmic Acyclovir Ophthalmic The excretion of Acyclovir can be decreased when combined with Lansoprazole.
Erdafitinib Erdafitinib The metabolism of Erdafitinib can be increased when combined with Lansoprazole.
Esomeprazole Injection Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Lansoprazole.
Alpelisib Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Lansoprazole.
Cladribine Cladribine Lansoprazole may decrease the excretion rate of Cladribine which could result in a higher serum level.
Darolutamide Darolutamide Lansoprazole may decrease the excretion rate of Darolutamide which could result in a higher serum level.
Triclabendazole Triclabendazole The metabolism of Lansoprazole can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The metabolism of Entrectinib can be increased when combined with Lansoprazole.
Pexidartinib Pexidartinib The serum concentration of Pexidartinib can be decreased when it is combined with Lansoprazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Lansoprazole.
Pitolisant Pitolisant The serum concentration of Lansoprazole can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Fedratinib can be decreased when combined with Lansoprazole.
Lefamulin Lefamulin The metabolism of Lefamulin can be decreased when combined with Lansoprazole.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Lansoprazole.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Lansoprazole.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be increased when combined with Lansoprazole.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Lansoprazole.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Lansoprazole.
Lumateperone Lumateperone The serum concentration of Lumateperone can be decreased when it is combined with Lansoprazole.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Lansoprazole.
Tazemetostat Tazemetostat Lansoprazole may decrease the excretion rate of Tazemetostat which could result in a higher serum level.
Cenobamate Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Lansoprazole.
Ozanimod Ozanimod Lansoprazole may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Lansoprazole.
Rimegepant Rimegepant The metabolism of Rimegepant can be increased when combined with Lansoprazole.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Lansoprazole.
Ripretinib Ripretinib Lansoprazole may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Selpercatinib Selpercatinib The serum concentration of Lansoprazole can be decreased when it is combined with Selpercatinib.
Capmatinib Capmatinib The serum concentration of Capmatinib can be decreased when it is combined with Lansoprazole.
Lemborexant Lemborexant The serum concentration of Lemborexant can be decreased when it is combined with Lansoprazole.
Fostemsavir Fostemsavir Lansoprazole may decrease the excretion rate of Fostemsavir which could result in a higher serum level.
Octreotide Octreotide Lansoprazole can cause a decrease in the absorption of Octreotide resulting in a reduced serum concentration and potentially a decrease in efficacy.
Pralsetinib Pralsetinib Lansoprazole may decrease the excretion rate of Pralsetinib which could result in a higher serum level.
Opicapone Opicapone The metabolism of Lansoprazole can be decreased when combined with Opicapone.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Lansoprazole can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be increased when combined with Lansoprazole.
Theophylline Theophylline Lansoprazole may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Indomethacin Indomethacin The excretion of Indomethacin can be decreased when combined with Lansoprazole.
Mefenamic Acid Mefenamic Acid The metabolism of Lansoprazole can be decreased when combined with Mefenamic acid.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Lansoprazole.
Trazodone Trazodone The metabolism of Trazodone can be decreased when combined with Lansoprazole.
Floxuridine Floxuridine The metabolism of Lansoprazole can be decreased when combined with Floxuridine.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Lansoprazole.
Methotrexate Injection Methotrexate Injection The serum concentration of Methotrexate can be increased when it is combined with Lansoprazole.
Primidone Primidone The metabolism of Primidone can be decreased when combined with Lansoprazole.
Methsuximide Methsuximide The metabolism of Methsuximide can be decreased when combined with Lansoprazole.
Chlorpromazine Chlorpromazine The metabolism of Chlorpromazine can be increased when combined with Lansoprazole.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Lansoprazole.
Lorazepam Lorazepam The metabolism of Lorazepam can be increased when combined with Lansoprazole.
Codeine Codeine The metabolism of Codeine can be decreased when combined with Lansoprazole.
Tranylcypromine Tranylcypromine The metabolism of Lansoprazole can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Lansoprazole can be decreased when combined with Phenelzine.
Tetracycline Tetracycline The excretion of Tetracycline can be decreased when combined with Lansoprazole.
Prochlorperazine Prochlorperazine The metabolism of Prochlorperazine can be increased when combined with Lansoprazole.
Thioridazine Thioridazine The metabolism of Thioridazine can be decreased when combined with Lansoprazole.
Dapsone Dapsone The metabolism of Dapsone can be decreased when combined with Lansoprazole.
Sulfadiazine Sulfadiazine The metabolism of Lansoprazole can be decreased when combined with Sulfadiazine.
Oxycodone Oxycodone The metabolism of Oxycodone can be decreased when combined with Lansoprazole.
Methadone Methadone The metabolism of Methadone can be decreased when combined with Lansoprazole.
Oxybutynin Oxybutynin The metabolism of Lansoprazole can be decreased when combined with Oxybutynin.
Benztropine Benztropine The metabolism of Benzatropine can be decreased when combined with Lansoprazole.
Maprotiline Maprotiline The metabolism of Maprotiline can be decreased when combined with Lansoprazole.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Lansoprazole.
Perphenazine Perphenazine The metabolism of Perphenazine can be decreased when combined with Lansoprazole.
Phentermine Phentermine The metabolism of Phentermine can be increased when combined with Lansoprazole.
Methylphenidate Methylphenidate Lansoprazole can cause an increase in the absorption of Methylphenidate resulting in an increased serum concentration and potentially a worsening of adverse effects.
Amoxapine Amoxapine The metabolism of Amoxapine can be decreased when combined with Lansoprazole.
Sulfasalazine Sulfasalazine Lansoprazole may decrease the excretion rate of Sulfasalazine which could result in a higher serum level.
Hydrocortisone Hydrocortisone The excretion of Hydrocortisone can be decreased when combined with Lansoprazole.
Doxorubicin Doxorubicin The metabolism of Doxorubicin can be increased when combined with Lansoprazole.
Dactinomycin Dactinomycin Lansoprazole may decrease the excretion rate of Dactinomycin which could result in a higher serum level.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be increased when combined with Lansoprazole.
Clonidine Clonidine The metabolism of Clonidine can be increased when combined with Lansoprazole.
Prazosin Prazosin Lansoprazole may decrease the excretion rate of Prazosin which could result in a higher serum level.
Cimetidine Cimetidine The excretion of Cimetidine can be decreased when combined with Lansoprazole.
Warfarin Warfarin The therapeutic efficacy of Warfarin can be increased when used in combination with Lansoprazole.
Clonazepam Clonazepam The metabolism of Clonazepam can be increased when combined with Lansoprazole.
Loperamide Loperamide The metabolism of Loperamide can be decreased when combined with Lansoprazole.
Promethazine Promethazine The metabolism of Lansoprazole can be decreased when combined with Promethazine.
Daunorubicin Daunorubicin Lansoprazole may decrease the excretion rate of Daunorubicin which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Lansoprazole may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin Griseofulvin The metabolism of Lansoprazole can be increased when combined with Griseofulvin.
Methenamine Methenamine The therapeutic efficacy of Methenamine can be decreased when used in combination with Lansoprazole.
Digoxin Digoxin The serum concentration of Digoxin can be increased when it is combined with Lansoprazole.
Chloroquine Chloroquine The metabolism of Chloroquine can be decreased when combined with Lansoprazole.
Quinine Quinine The metabolism of Quinine can be decreased when combined with Lansoprazole.
Sulfinpyrazone Sulfinpyrazone The metabolism of Lansoprazole can be decreased when combined with Sulfinpyrazone.
Isosorbide Isosorbide The metabolism of Isosorbide can be increased when combined with Lansoprazole.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be increased when combined with Lansoprazole.
Secobarbital Secobarbital The metabolism of Lansoprazole can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Lansoprazole.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Lansoprazole.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Lansoprazole.
Probenecid Probenecid The metabolism of Lansoprazole can be decreased when combined with Probenecid.
Quinidine Quinidine The metabolism of Quinidine can be increased when combined with Lansoprazole.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Lansoprazole.
Isoniazid Isoniazid The metabolism of Lansoprazole can be decreased when combined with Isoniazid.
Rifampin Rifampin Lansoprazole can cause a decrease in the absorption of Rifampicin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Valproic Acid Valproic Acid The metabolism of Valproic acid can be decreased when combined with Lansoprazole.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be increased when combined with Lansoprazole.
Levothyroxine Levothyroxine Lansoprazole can cause a decrease in the absorption of Levothyroxine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Methimazole Methimazole The metabolism of Lansoprazole can be decreased when combined with Methimazole.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Lansoprazole.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Lansoprazole.
Tolazamide Tolazamide The metabolism of Tolazamide can be decreased when combined with Lansoprazole.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Lansoprazole.
Dinoprostone Dinoprostone The excretion of Dinoprostone can be decreased when combined with Lansoprazole.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Lansoprazole.
Meclizine Meclizine The metabolism of Meclizine can be decreased when combined with Lansoprazole.
Hydrochlorothiazide Hydrochlorothiazide The excretion of Hydrochlorothiazide can be decreased when combined with Lansoprazole.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Lansoprazole.
Carisoprodol Carisoprodol The metabolism of Carisoprodol can be decreased when combined with Lansoprazole.
Folic Acid Folic Acid Lansoprazole may decrease the excretion rate of Folic acid which could result in a higher serum level.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Lansoprazole.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be increased when combined with Lansoprazole.
Spironolactone Spironolactone The metabolism of Lansoprazole can be decreased when combined with Spironolactone.
Mercaptopurine Mercaptopurine The excretion of Mercaptopurine can be decreased when combined with Lansoprazole.
Nadolol Nadolol The metabolism of Nadolol can be decreased when combined with Lansoprazole.
Allopurinol Allopurinol Lansoprazole may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Lansoprazole.
Colchicine Colchicine The metabolism of Colchicine can be decreased when combined with Lansoprazole.
Cefaclor Cefaclor The excretion of Cefaclor can be decreased when combined with Lansoprazole.
Cefazolin Injection Cefazolin Injection The excretion of Cefazolin can be decreased when combined with Lansoprazole.
Cephalexin Cephalexin The excretion of Cephalexin can be decreased when combined with Lansoprazole.
Iron Supplements Iron Supplements Lansoprazole can cause a decrease in the absorption of Iron resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ketoconazole Ketoconazole Ketoconazole can cause a decrease in the absorption of Lansoprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be increased when combined with Lansoprazole.
Vincristine Injection Vincristine Injection The metabolism of Vincristine can be increased when combined with Lansoprazole.
Captopril Captopril Lansoprazole can cause a decrease in the absorption of Captopril resulting in a reduced serum concentration and potentially a decrease in efficacy.
Vinblastine Vinblastine The metabolism of Vinblastine can be increased when combined with Lansoprazole.
Metoprolol Metoprolol The metabolism of Metoprolol can be increased when combined with Lansoprazole.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Lansoprazole.
Alprazolam Alprazolam The metabolism of Alprazolam can be decreased when combined with Lansoprazole.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Lansoprazole.
Diltiazem Diltiazem The metabolism of Lansoprazole can be decreased when combined with Diltiazem.
Nifedipine Nifedipine The metabolism of Lansoprazole can be decreased when combined with Nifedipine.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Lansoprazole.
Verapamil Verapamil The metabolism of Verapamil can be decreased when combined with Lansoprazole.
Atenolol Atenolol The metabolism of Atenolol can be decreased when combined with Lansoprazole.
Pindolol Pindolol The metabolism of Pindolol can be decreased when combined with Lansoprazole.
Cisplatin Injection Cisplatin Injection The metabolism of Lansoprazole can be decreased when combined with Cisplatin.
Piroxicam Piroxicam The metabolism of Lansoprazole can be decreased when combined with Piroxicam.
Bumetanide Bumetanide The excretion of Bumetanide can be decreased when combined with Lansoprazole.
Etoposide Etoposide The metabolism of Etoposide can be increased when combined with Lansoprazole.
Glyburide Glyburide The metabolism of Lansoprazole can be decreased when combined with Glyburide.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Lansoprazole.
Pentamidine Injection Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Lansoprazole.
Labetalol Labetalol The metabolism of Labetalol can be decreased when combined with Lansoprazole.
Gemfibrozil Gemfibrozil The metabolism of Lansoprazole can be decreased when combined with Gemfibrozil.
Ketoprofen Ketoprofen The metabolism of Ketoprofen can be decreased when combined with Lansoprazole.
Pimozide Pimozide The metabolism of Pimozide can be increased when combined with Lansoprazole.
Flurbiprofen Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Lansoprazole.
Amiodarone Amiodarone The metabolism of Amiodarone can be increased when combined with Lansoprazole.
Buspirone Buspirone The metabolism of Buspirone can be decreased when combined with Lansoprazole.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Lansoprazole.
Mesalamine Mesalamine Lansoprazole can cause a decrease in the absorption of Mesalazine resulting in a reduced serum concentration and potentially a decrease in efficacy.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Lansoprazole.
Fluoxetine Fluoxetine The metabolism of Fluoxetine can be decreased when combined with Lansoprazole.
Clozapine Clozapine The metabolism of Lansoprazole can be decreased when combined with Clozapine.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Lansoprazole.
Etodolac Etodolac The metabolism of Etodolac can be decreased when combined with Lansoprazole.
Felodipine Felodipine The metabolism of Lansoprazole can be decreased when combined with Felodipine.
Nabumetone Nabumetone The metabolism of Nabumetone can be decreased when combined with Lansoprazole.
Pravastatin Pravastatin The excretion of Pravastatin can be decreased when combined with Lansoprazole.
Quinapril Quinapril The excretion of Quinapril can be decreased when combined with Lansoprazole.
Simvastatin Simvastatin The metabolism of Lansoprazole can be decreased when combined with Simvastatin.
Amlodipine Amlodipine The metabolism of Amlodipine can be increased when combined with Lansoprazole.
Teniposide Injection Teniposide Injection The metabolism of Teniposide can be increased when combined with Lansoprazole.
Itraconazole Itraconazole Itraconazole can cause a decrease in the absorption of Lansoprazole resulting in a reduced serum concentration and potentially a decrease in efficacy.
Atovaquone Atovaquone The metabolism of Lansoprazole can be decreased when combined with Atovaquone.
Rifabutin Rifabutin The metabolism of Lansoprazole can be increased when combined with Rifabutin.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Lansoprazole.
Zolpidem Zolpidem The metabolism of Zolpidem can be increased when combined with Lansoprazole.
Doxazosin Doxazosin The metabolism of Doxazosin can be decreased when combined with Lansoprazole.
Omeprazole Omeprazole The metabolism of Omeprazole can be decreased when combined with Lansoprazole.
Cisapride Cisapride The metabolism of Cisapride can be increased when combined with Lansoprazole.
Fluvastatin Fluvastatin The metabolism of Lansoprazole can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Lansoprazole.
Famciclovir Famciclovir The metabolism of Famciclovir can be increased when combined with Lansoprazole.
Fluvoxamine Fluvoxamine The metabolism of Lansoprazole can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Nefazodone can be decreased when combined with Lansoprazole.
Losartan Losartan The metabolism of Losartan can be decreased when combined with Lansoprazole.
Valacyclovir Valacyclovir The excretion of Valaciclovir can be decreased when combined with Lansoprazole.
Tramadol Tramadol The metabolism of Tramadol can be decreased when combined with Lansoprazole.
Vinorelbine Injection Vinorelbine Injection The metabolism of Vinorelbine can be increased when combined with Lansoprazole.
Alprostadil Urogenital Alprostadil Urogenital The excretion of Alprostadil can be decreased when combined with Lansoprazole.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be increased when combined with Lansoprazole.
Nicardipine Nicardipine The metabolism of Lansoprazole can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Bupropion can be decreased when combined with Lansoprazole.
Ticlopidine Ticlopidine The metabolism of Lansoprazole can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The serum concentration of Saquinavir can be increased when it is combined with Lansoprazole.
Lamivudine Lamivudine Lansoprazole may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole Lansoprazole may decrease the excretion rate of Riluzole which could result in a higher serum level.
Glimepiride Glimepiride The metabolism of Glimepiride can be decreased when combined with Lansoprazole.
Anastrozole Anastrozole The metabolism of Anastrozole can be decreased when combined with Lansoprazole.
Indinavir Indinavir Lansoprazole can cause a decrease in the absorption of Indinavir resulting in a reduced serum concentration and potentially a decrease in efficacy.
Ritonavir Ritonavir The serum concentration of Lansoprazole can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be increased when combined with Lansoprazole.
Clomipramine Clomipramine The metabolism of Clomipramine can be increased when combined with Lansoprazole.
Zafirlukast Zafirlukast The metabolism of Lansoprazole can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine The metabolism of Mirtazapine can be decreased when combined with Lansoprazole.
Topiramate Topiramate The metabolism of Lansoprazole can be decreased when combined with Topiramate.
Zileuton Zileuton The metabolism of Zileuton can be decreased when combined with Lansoprazole.
Valsartan Valsartan The metabolism of Lansoprazole can be decreased when combined with Valsartan.
Donepezil Donepezil Lansoprazole may decrease the excretion rate of Donepezil which could result in a higher serum level.
Nelfinavir Nelfinavir The serum concentration of Nelfinavir can be decreased when it is combined with Lansoprazole.
Fexofenadine Fexofenadine The excretion of Fexofenadine can be decreased when combined with Lansoprazole.
Azithromycin Azithromycin The metabolism of Azithromycin can be increased when combined with Lansoprazole.
Loratadine Loratadine The metabolism of Lansoprazole can be decreased when combined with Loratadine.
Carvedilol Carvedilol The metabolism of Carvedilol can be decreased when combined with Lansoprazole.
Nilutamide Nilutamide The metabolism of Lansoprazole can be decreased when combined with Nilutamide.
Selegiline Selegiline The metabolism of Selegiline can be decreased when combined with Lansoprazole.
Bicalutamide Bicalutamide The metabolism of Lansoprazole can be increased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Lansoprazole can be decreased when combined with Sertraline.
Propafenone Propafenone The metabolism of Propafenone can be decreased when combined with Lansoprazole.
Letrozole Letrozole The metabolism of Lansoprazole can be decreased when combined with Letrozole.
Raloxifene Raloxifene Lansoprazole may decrease the excretion rate of Raloxifene which could result in a higher serum level.
Irbesartan Irbesartan The metabolism of Lansoprazole can be decreased when combined with Irbesartan.
Tamsulosin Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Lansoprazole.
Quetiapine Quetiapine The metabolism of Quetiapine can be decreased when combined with Lansoprazole.
Paroxetine Paroxetine The metabolism of Lansoprazole can be decreased when combined with Paroxetine.
Tolcapone Tolcapone The metabolism of Lansoprazole can be decreased when combined with Tolcapone.
Citalopram Citalopram The serum concentration of Citalopram can be increased when it is combined with Lansoprazole.
Capecitabine Capecitabine The metabolism of Lansoprazole can be decreased when combined with Capecitabine.
Efavirenz Efavirenz The metabolism of Lansoprazole can be decreased when combined with Efavirenz.
Sildenafil Sildenafil The metabolism of Sildenafil can be decreased when combined with Lansoprazole.
Pioglitazone Pioglitazone The metabolism of Lansoprazole can be decreased when combined with Pioglitazone.
Celecoxib Celecoxib Lansoprazole may decrease the excretion rate of Celecoxib which could result in a higher serum level.
Rosiglitazone Rosiglitazone The metabolism of Lansoprazole can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Lansoprazole.
Thalidomide Thalidomide The metabolism of Lansoprazole can be decreased when combined with Thalidomide.
Oseltamivir Oseltamivir The excretion of Oseltamivir can be decreased when combined with Lansoprazole.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Lansoprazole.
Galantamine Galantamine The metabolism of Galantamine can be decreased when combined with Lansoprazole.
Rabeprazole Rabeprazole The metabolism of Rabeprazole can be decreased when combined with Lansoprazole.
Terbinafine Terbinafine The metabolism of Terbinafine can be decreased when combined with Lansoprazole.

* This branded product is no longer on the market. Generic alternatives may be available.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists