Theophylline

Generic name: Pronounced as (the off'' i lin)
Brand names
  • Accurbron®
  • Aerolate®
  • Aquaphyllin®
  • Asbron®
  • Bronkodyl®
  • Duraphyl®
  • Elixicon®
  • Elixomin®
  • Elixophyllin®
  • Labid®
  • Lanophyllin®
  • Quibron-T®
  • Slo-Bid®
  • Slo-Phyllin®
  • Somophyllin®
  • Sustaire®
  • Synophylate®
  • T-Phyll®
  • Theo-24®
  • Theo-Dur®
  • Theobid®
  • Theochron®
  • Theoclear®
  • Theolair®
  • Theolixir®
  • Theophyl®
  • Theovent®
  • Uni-dur®
  • Uniphyl®
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Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 11/15/2019

Theophylline is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe.

Theophylline comes as an extended-release (long-acting) tablet, extended-release capsule, and a solution (liquid) to take by mouth. It usually is taken every 6, 8, 12, or 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take theophylline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Take this medication with a full glass of water on an empty stomach, at least 1 hour before or 2 hours after a meal. Extended-release capsules (e.g., Theo-Dur Sprinkles) may be swallowed whole or opened and the contents mixed with soft food and swallowed without chewing.

Swallow the extended-release tablets whole; do not chew or crush them.

Theophylline controls symptoms of asthma and other lung diseases but does not cure them. Continue to take theophylline even if you feel well. Do not stop taking theophylline without talking to your doctor.

Theophylline is sometimes used to treat breathing problems in premature infants. Talk to your doctor about the possible risks of using this drug for your baby's condition.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking theophylline,

  • tell your doctor and pharmacist if you are allergic to theophylline, any other medications, or any of the ingredients in theophylline preparations. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what prescription medications you are taking, especially allopurinol (Zyloprim), azithromycin (Zithromax), carbamazepine (Tegretol), cimetidine (Tagamet), ciprofloxacin (Cipro), clarithromycin (Biaxin), diuretics ('water pills'), erythromycin, lithium (Eskalith, Lithobid), oral contraceptives, phenytoin (Dilantin), prednisone (Deltasone), propranolol (Inderal), rifampin (Rifadin), tetracycline (Sumycin), and other medications for infections or heart disease.

  • tell your doctor and pharmacist what prescription, nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: ephedrine, epinephrine, phenylephrine, phenylpropanolamine, or pseudoephedrine. Many other medications may also interact with theophylline, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

  • tell your doctor if you have or have ever had seizures, ulcers, heart disease, an overactive or underactive thyroid gland, high blood pressure, or liver disease or if you have a history of alcohol abuse.

  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking theophylline, call your doctor.

  • tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of theophylline.

Drinking or eating foods high in caffeine, like coffee, tea, cocoa, and chocolate, may increase the side effects caused by theophylline. Avoid large amounts of these substances while you are taking theophylline.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. If you become severely short of breath, call your doctor.

  • Theophylline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away.

    • upset stomach

    • stomach pain

    • diarrhea

    • headache

    • restlessness

    • difficulty falling asleep or staying asleep

    • irritability

  • Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

    • vomiting

    • increased or rapid heart rate

    • irregular heartbeat

    • seizures

    • rash

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to theophylline.

Do not change from one brand of theophylline to another without talking to your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The metabolism of Theophylline can be decreased when combined with Moxifloxacin.
Repaglinide Repaglinide The metabolism of Repaglinide can be decreased when combined with Theophylline.
Montelukast Montelukast The metabolism of Theophylline can be decreased when combined with Montelukast.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The metabolism of Theophylline can be increased when combined with Insulin glargine.
Leflunomide Leflunomide The serum concentration of Theophylline can be decreased when it is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Theophylline can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Theophylline can be decreased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Theophylline.
Dolasetron Dolasetron The metabolism of Dolasetron can be decreased when combined with Theophylline.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Theophylline.
Anagrelide Anagrelide The metabolism of Theophylline can be decreased when combined with Anagrelide.
Candesartan Candesartan The metabolism of Theophylline can be decreased when combined with Candesartan.
Cilostazol Cilostazol The metabolism of Cilostazol can be decreased when combined with Theophylline.
Clopidogrel Clopidogrel The metabolism of Theophylline can be decreased when combined with Clopidogrel.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The therapeutic efficacy of Erythromycin can be decreased when used in combination with Theophylline.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The metabolism of Theophylline can be decreased when combined with Conjugated estrogens.
Fenofibrate Fenofibrate The metabolism of Theophylline can be decreased when combined with Fenofibrate.
Methylergonovine Methylergonovine The metabolism of Theophylline can be decreased when combined with Methylergometrine.
Paregoric Paregoric The metabolism of Morphine can be decreased when combined with Theophylline.
Penbutolol Penbutolol The metabolism of Theophylline can be decreased when combined with Acebutolol.
Ranitidine Ranitidine The metabolism of Theophylline can be decreased when combined with Ranitidine.
Tacrolimus Tacrolimus The metabolism of Theophylline can be decreased when combined with Tacrolimus.
Tizanidine Tizanidine The metabolism of Tizanidine can be decreased when combined with Theophylline.
Triamcinolone Triamcinolone The metabolism of Theophylline can be increased when combined with Triamcinolone.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Theophylline.
Doxycycline Injection Doxycycline Injection The metabolism of Theophylline can be decreased when combined with Doxycycline.
Famotidine Injection Famotidine Injection The metabolism of Theophylline can be decreased when combined with Famotidine.
Fluconazole Injection Fluconazole Injection The serum concentration of Theophylline can be increased when it is combined with Fluconazole.
Interferon Beta-1b Injection Interferon Beta-1b Injection The metabolism of Theophylline can be decreased when combined with Interferon beta-1b.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The metabolism of Theophylline can be decreased when combined with Interferon gamma-1b.
Levofloxacin Injection Levofloxacin Injection The metabolism of Theophylline can be decreased when combined with Levofloxacin.
Meperidine Injection Meperidine Injection The metabolism of Theophylline can be increased when combined with Meperidine.
Methylprednisolone Injection Methylprednisolone Injection The metabolism of Theophylline can be increased when combined with Methylprednisolone.
Metoclopramide Injection Metoclopramide Injection The metabolism of Theophylline can be decreased when combined with Metoclopramide.
Metronidazole Injection Metronidazole Injection The metabolism of Theophylline can be decreased when combined with Metronidazole.
Morphine Injection Morphine Injection The metabolism of Morphine can be decreased when combined with Theophylline.
Zidovudine Injection Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Theophylline.
Altretamine Altretamine The metabolism of Theophylline can be decreased when combined with Amphetamine.
Cyclosporine Cyclosporine The metabolism of Theophylline can be decreased when combined with Cyclosporine.
Ondansetron Ondansetron The metabolism of Theophylline can be decreased when combined with Ondansetron.
Torsemide Torsemide The metabolism of Theophylline can be decreased when combined with Torasemide.
Alosetron Alosetron The metabolism of Theophylline can be decreased when combined with Alosetron.
Entacapone Entacapone The metabolism of Theophylline can be decreased when combined with Entacapone.
Hydroxychloroquine Hydroxychloroquine The metabolism of Theophylline can be decreased when combined with Hydroxychloroquine.
Orlistat Orlistat The metabolism of Theophylline can be increased when combined with Orlistat.
Oxcarbazepine Oxcarbazepine The metabolism of Theophylline can be increased when combined with Oxcarbazepine.
Zaleplon Zaleplon Zaleplon may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Anakinra Anakinra The metabolism of Theophylline can be increased when combined with Anakinra.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Theophylline.
Etanercept Injection Etanercept Injection The metabolism of Theophylline can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Theophylline can be increased when combined with Modafinil.
Tenofovir Tenofovir The metabolism of Theophylline can be decreased when combined with Tenofovir.
Sirolimus Sirolimus The metabolism of Theophylline can be decreased when combined with Sirolimus.
Epinephrine Injection Epinephrine Injection The metabolism of Theophylline can be decreased when combined with Epinephrine.
Escitalopram Escitalopram The serum concentration of Theophylline can be increased when it is combined with Escitalopram.
Zonisamide Zonisamide Zonisamide may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Adalimumab Injection Adalimumab Injection The serum concentration of Theophylline can be decreased when it is combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Theophylline.
Atomoxetine Atomoxetine The metabolism of Theophylline can be decreased when combined with Atomoxetine.
Atazanavir Atazanavir The metabolism of Theophylline can be decreased when combined with Atazanavir.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Theophylline.
Eletriptan Eletriptan The metabolism of Theophylline can be decreased when combined with Eletriptan.
Mefloquine Mefloquine The metabolism of Theophylline can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin The metabolism of Theophylline can be decreased when combined with Rosuvastatin.
Aprepitant Aprepitant The metabolism of Theophylline can be decreased when combined with Aprepitant.
Interferon Beta-1a Subcutaneous Injection Interferon Beta-1a Subcutaneous Injection The metabolism of Theophylline can be decreased when combined with Interferon beta-1a.
Tegaserod Tegaserod The metabolism of Theophylline can be decreased when combined with Tegaserod.
Frovatriptan Frovatriptan The metabolism of Frovatriptan can be decreased when combined with Theophylline.
Gemifloxacin Gemifloxacin The metabolism of Theophylline can be decreased when combined with Gemifloxacin.
Progesterone Progesterone The metabolism of Theophylline can be increased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Theophylline.
Infliximab Injection Infliximab Injection The metabolism of Theophylline can be increased when combined with Infliximab.
Protriptyline Protriptyline The metabolism of Protriptyline can be decreased when combined with Theophylline.
Rifaximin Rifaximin The metabolism of Theophylline can be increased when combined with Rifaximin.
Duloxetine Duloxetine The metabolism of Theophylline can be decreased when combined with Duloxetine.
Norethindrone Norethindrone Norethisterone may decrease the excretion rate of Theophylline which could result in a higher serum level.
Trospium Trospium The metabolism of Theophylline can be decreased when combined with Trospium.
Bosentan Bosentan The metabolism of Theophylline can be increased when combined with Bosentan.
Cinacalcet Cinacalcet The metabolism of Cinacalcet can be decreased when combined with Theophylline.
Erlotinib Erlotinib The metabolism of Theophylline can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Theophylline.
Solifenacin Solifenacin The metabolism of Solifenacin can be decreased when combined with Theophylline.
Voriconazole Voriconazole The metabolism of Theophylline can be decreased when combined with Voriconazole.
Dextroamphetamine Dextroamphetamine The metabolism of Theophylline can be decreased when combined with Amphetamine.
Entecavir Entecavir The metabolism of Entecavir can be decreased when combined with Theophylline.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The metabolism of Theophylline can be decreased when combined with Peginterferon alfa-2a.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The serum concentration of Theophylline can be increased when it is combined with Peginterferon alfa-2b.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Theophylline.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Theophylline.
Pregabalin Pregabalin The therapeutic efficacy of Theophylline can be decreased when used in combination with Pregabalin.
Deferasirox Deferasirox The serum concentration of Theophylline can be increased when it is combined with Deferasirox.
Phenylephrine Phenylephrine The metabolism of Theophylline can be increased when combined with Phenylephrine.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Theophylline.
Felbamate Felbamate The metabolism of Theophylline can be increased when combined with Felbamate.
Ranolazine Ranolazine The serum concentration of Theophylline can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Theophylline can be increased when combined with Abatacept.
Rasagiline Rasagiline The metabolism of Rasagiline can be decreased when combined with Theophylline.
Imatinib Imatinib The metabolism of Theophylline can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin The metabolism of Sitagliptin can be decreased when combined with Theophylline.
Gefitinib Gefitinib The metabolism of Theophylline can be decreased when combined with Gefitinib.
Paliperidone Paliperidone The metabolism of Paliperidone can be decreased when combined with Theophylline.
Bortezomib Bortezomib The metabolism of Theophylline can be decreased when combined with Bortezomib.
Hepatitis B Vaccine Hepatitis B Vaccine The serum concentration of Theophylline can be increased when it is combined with Hepatitis B Vaccine (Recombinant).
Influenza Vaccine, Inactivated or Recombinant Influenza Vaccine, Inactivated or Recombinant The serum concentration of Theophylline can be increased when it is combined with Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated).
Influenza Vaccine, Live Intranasal Influenza Vaccine, Live Intranasal The serum concentration of Theophylline can be increased when it is combined with Typhoid Vaccine Live.
Live Shingles (Zoster) Vaccine (ZVL) Live Shingles (Zoster) Vaccine (ZVL) The serum concentration of Theophylline can be increased when it is combined with Varicella Zoster Vaccine (Live/attenuated).
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The metabolism of Theophylline can be increased when combined with Insulin glulisine.
Posaconazole Posaconazole The metabolism of Theophylline can be decreased when combined with Posaconazole.
Primaquine Primaquine The metabolism of Theophylline can be decreased when combined with Primaquine.
Darunavir Darunavir The serum concentration of Theophylline can be increased when it is combined with Darunavir.
Pemetrexed Injection Pemetrexed Injection The metabolism of Pemetrexed can be decreased when combined with Theophylline.
Lisdexamfetamine Lisdexamfetamine The metabolism of Theophylline can be decreased when combined with Lisdexamfetamine.
Nabilone Nabilone The metabolism of Theophylline can be decreased when combined with Nabilone.
Sorafenib Sorafenib The metabolism of Theophylline can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Theophylline can be decreased when combined with Sunitinib.
Lapatinib Lapatinib The metabolism of Theophylline can be decreased when combined with Lapatinib.
Dasatinib Dasatinib The metabolism of Theophylline can be decreased when combined with Dasatinib.
Mexiletine Mexiletine The metabolism of Theophylline can be decreased when combined with Mexiletine.
Armodafinil Armodafinil The metabolism of Theophylline can be increased when combined with Armodafinil.
Ivermectin Ivermectin The metabolism of Theophylline can be increased when combined with Ivermectin.
Temsirolimus Temsirolimus The metabolism of Theophylline can be decreased when combined with Temsirolimus.
Nilotinib Nilotinib The metabolism of Theophylline can be decreased when combined with Nilotinib.
Bexarotene Bexarotene The metabolism of Theophylline can be increased when combined with Bexarotene.
Budesonide Budesonide The metabolism of Theophylline can be increased when combined with Budesonide.
Chloramphenicol Injection Chloramphenicol Injection The metabolism of Theophylline can be decreased when combined with Chloramphenicol.
Etravirine Etravirine The metabolism of Theophylline can be increased when combined with Etravirine.
Mitoxantrone Injection Mitoxantrone Injection The metabolism of Theophylline can be decreased when combined with Mitoxantrone.
Desvenlafaxine Desvenlafaxine The metabolism of Theophylline can be decreased when combined with Desvenlafaxine.
Cevimeline Cevimeline The metabolism of Theophylline can be decreased when combined with Cevimeline.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Theophylline.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Theophylline.
Bendamustine Injection Bendamustine Injection The metabolism of Bendamustine can be decreased when combined with Theophylline.
Pilocarpine Pilocarpine The metabolism of Theophylline can be decreased when combined with Pilocarpine.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Theophylline.
Certolizumab Injection Certolizumab Injection The metabolism of Theophylline can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The metabolism of Theophylline can be decreased when combined with Ixabepilone.
Praziquantel Praziquantel The metabolism of Praziquantel can be decreased when combined with Theophylline.
Mitotane Mitotane The metabolism of Theophylline can be increased when combined with Mitotane.
Rufinamide Rufinamide The metabolism of Theophylline can be increased when combined with Rufinamide.
Midazolam Midazolam The metabolism of Midazolam can be decreased when combined with Theophylline.
Eltrombopag Eltrombopag The metabolism of Theophylline can be decreased when combined with Eltrombopag.
Milnacipran Milnacipran The metabolism of Theophylline can be decreased when combined with Milnacipran.
Febuxostat Febuxostat The serum concentration of the active metabolites of Theophylline can be increased when Theophylline is used in combination with Febuxostat.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Theophylline.
Betaxolol Betaxolol The metabolism of Theophylline can be decreased when combined with Betaxolol.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Theophylline.
Lacosamide Lacosamide The metabolism of Theophylline can be decreased when combined with Lacosamide.
Everolimus Everolimus The metabolism of Theophylline can be decreased when combined with Everolimus.
Dronedarone Dronedarone The serum concentration of Dronedarone can be decreased when it is combined with Theophylline.
Palonosetron Injection Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Theophylline.
Tapentadol Tapentadol The metabolism of Theophylline can be decreased when combined with Tapentadol.
Topotecan Topotecan The metabolism of Theophylline can be increased when combined with Topotecan.
Golimumab Injection Golimumab Injection The metabolism of Theophylline can be increased when combined with Golimumab.
Pazopanib Pazopanib The metabolism of Theophylline can be decreased when combined with Pazopanib.
Asenapine Asenapine The metabolism of Asenapine can be decreased when combined with Theophylline.
Vigabatrin Vigabatrin Vigabatrin may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Pitavastatin Pitavastatin The metabolism of Pitavastatin can be decreased when combined with Theophylline.
Albendazole Albendazole The metabolism of Theophylline can be decreased when combined with Albendazole.
Levonorgestrel Levonorgestrel Levonorgestrel may decrease the excretion rate of Theophylline which could result in a higher serum level.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Theophylline.
Tocilizumab Injection Tocilizumab Injection The metabolism of Theophylline can be increased when combined with Tocilizumab.
Dalfampridine Dalfampridine The risk or severity of seizure can be increased when Theophylline is combined with Dalfampridine.
Fingolimod Fingolimod The metabolism of Fingolimod can be decreased when combined with Theophylline.
Cabazitaxel Injection Cabazitaxel Injection The metabolism of Cabazitaxel can be decreased when combined with Theophylline.
Acetaminophen Injection Acetaminophen Injection Acetaminophen may increase the hepatotoxic activities of Theophylline.
Vilazodone Vilazodone The metabolism of Theophylline can be decreased when combined with Vilazodone.
Denileukin Diftitox Injection Denileukin Diftitox Injection The metabolism of Theophylline can be decreased when combined with Aldesleukin.
Terbutaline Injection Terbutaline Injection The risk or severity of adverse effects can be increased when Terbutaline is combined with Theophylline.
Roflumilast Roflumilast The metabolism of Theophylline can be decreased when combined with Roflumilast.
Linagliptin Linagliptin The metabolism of Theophylline can be decreased when combined with Linagliptin.
Rilpivirine Rilpivirine The metabolism of Theophylline can be decreased when combined with Rilpivirine.
Telaprevir Telaprevir The metabolism of Theophylline can be decreased when combined with Glecaprevir.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Theophylline can be increased when combined with Cyclophosphamide.
Abiraterone Abiraterone The serum concentration of Theophylline can be increased when it is combined with Abiraterone.
Ticagrelor Ticagrelor The metabolism of Theophylline can be decreased when combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The metabolism of Theophylline can be decreased when combined with Brentuximab vedotin.
Clobazam Clobazam The metabolism of Theophylline can be decreased when combined with Clobazam.
Vemurafenib Vemurafenib The serum concentration of Theophylline can be increased when it is combined with Vemurafenib.
Vismodegib Vismodegib The metabolism of Theophylline can be decreased when combined with Vismodegib.
Ivacaftor Ivacaftor The metabolism of Theophylline can be decreased when combined with Ivacaftor.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Theophylline.
Crizotinib Crizotinib The metabolism of Theophylline can be decreased when combined with Crizotinib.
Cabergoline Cabergoline The metabolism of Theophylline can be decreased when combined with Cabergoline.
Naloxone Injection Naloxone Injection The metabolism of Theophylline can be decreased when combined with Naloxone.
Ezogabine Ezogabine Tiagabine may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Enzalutamide Enzalutamide The metabolism of Theophylline can be increased when combined with Enzalutamide.
Mirabegron Mirabegron The serum concentration of Theophylline can be increased when it is combined with Mirabegron.
Regorafenib Regorafenib The metabolism of Theophylline can be decreased when combined with Regorafenib.
Bosutinib Bosutinib The metabolism of Theophylline can be decreased when combined with Bosutinib.
Corticotropin, Repository Injection Corticotropin, Repository Injection The metabolism of Theophylline can be increased when combined with Corticotropin.
Teriflunomide Teriflunomide The serum concentration of Theophylline can be decreased when it is combined with Teriflunomide.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Theophylline can be decreased when combined with Cabozantinib.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Theophylline.
Ponatinib Ponatinib The metabolism of Theophylline can be decreased when combined with Ponatinib.
Pomalidomide Pomalidomide The metabolism of Pomalidomide can be decreased when combined with Theophylline.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The metabolism of Theophylline can be decreased when combined with Trastuzumab emtansine.
Apixaban Apixaban The metabolism of Apixaban can be decreased when combined with Theophylline.
Dabrafenib Dabrafenib The metabolism of Theophylline can be increased when combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Theophylline can be decreased when combined with Ospemifene.
Trametinib Trametinib The metabolism of Theophylline can be increased when combined with Trametinib.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Theophylline.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Theophylline.
Perampanel Perampanel The metabolism of Theophylline can be increased when combined with Perampanel.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Theophylline.
Lomitapide Lomitapide The metabolism of Lomitapide can be decreased when combined with Theophylline.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Theophylline.
Simeprevir Simeprevir The metabolism of Theophylline can be decreased when combined with Simeprevir.
Dapagliflozin Dapagliflozin The metabolism of Theophylline can be decreased when combined with Dapagliflozin.
Apremilast Apremilast The metabolism of Theophylline can be increased when combined with Apremilast.
Ceritinib Ceritinib The metabolism of Theophylline can be decreased when combined with Ceritinib.
Siltuximab Injection Siltuximab Injection The metabolism of Theophylline can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The metabolism of Theophylline can be increased when combined with Eslicarbazepine.
Belinostat Injection Belinostat Injection The metabolism of Theophylline can be increased when combined with Belinostat.
Idelalisib Idelalisib The metabolism of Theophylline can be decreased when combined with Idelalisib.
Testosterone Injection Testosterone Injection The metabolism of Theophylline can be increased when combined with Testosterone.
Oritavancin Injection Oritavancin Injection The metabolism of Theophylline can be increased when combined with Oritavancin.
Vorapaxar Vorapaxar The metabolism of Theophylline can be decreased when combined with Vorapaxar.
Hydrocodone Hydrocodone The metabolism of Theophylline can be decreased when combined with Hydrocodone.
Suvorexant Suvorexant The metabolism of Theophylline can be decreased when combined with Suvorexant.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The metabolism of Theophylline can be decreased when combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Theophylline can be decreased when combined with Olaparib.
Methamphetamine Methamphetamine The metabolism of Theophylline can be decreased when combined with Metamfetamine.
Tasimelteon Tasimelteon The metabolism of Theophylline can be decreased when combined with Tasimelteon.
Riociguat Riociguat Theophylline may increase the hypotensive activities of Riociguat.
Lanreotide Injection Lanreotide Injection The metabolism of Theophylline can be decreased when combined with Lanreotide.
Pirfenidone Pirfenidone The metabolism of Pirfenidone can be decreased when combined with Theophylline.
Nintedanib Nintedanib The metabolism of Theophylline can be decreased when combined with Nintedanib.
Secukinumab Injection Secukinumab Injection The metabolism of Theophylline can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Risperidone can be decreased when combined with Theophylline.
Palbociclib Palbociclib The metabolism of Theophylline can be decreased when combined with Palbociclib.
Insulin Human Inhalation Insulin Human Inhalation The metabolism of Theophylline can be increased when combined with Insulin human.
Lenvatinib Lenvatinib The metabolism of Theophylline can be increased when combined with Lenvatinib.
Naloxegol Naloxegol The metabolism of Theophylline can be decreased when combined with Naloxegol.
Panobinostat Panobinostat The metabolism of Theophylline can be decreased when combined with Panobinostat.
Haloperidol Injection Haloperidol Injection The serum concentration of Theophylline can be increased when it is combined with Haloperidol.
Isavuconazonium Injection Isavuconazonium Injection The metabolism of Theophylline can be increased when combined with Isavuconazonium.
Rolapitant Rolapitant The metabolism of Theophylline can be decreased when combined with Rolapitant.
Prednisolone Prednisolone The metabolism of Theophylline can be increased when combined with Prednisolone.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Theophylline.
Ziprasidone Injection Ziprasidone Injection The metabolism of Theophylline can be decreased when combined with Ziprasidone.
Cariprazine Cariprazine The metabolism of Cariprazine can be decreased when combined with Theophylline.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The metabolism of Theophylline can be increased when combined with Insulin degludec.
Cobimetinib Cobimetinib The metabolism of Theophylline can be decreased when combined with Cobimetinib.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Theophylline.
Osimertinib Osimertinib The serum concentration of Theophylline can be decreased when it is combined with Osimertinib.
Rifapentine Rifapentine The metabolism of Theophylline can be increased when combined with Rifapentine.
Lesinurad Lesinurad The metabolism of Theophylline can be increased when combined with Lesinurad.
Amphotericin B Liposomal Injection Amphotericin B Liposomal Injection The metabolism of Theophylline can be decreased when combined with Amphotericin B.
Dexamethasone Injection Dexamethasone Injection The metabolism of Theophylline can be increased when combined with Dexamethasone.
Brivaracetam Injection Brivaracetam Injection Brivaracetam may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Venetoclax Venetoclax The metabolism of Theophylline can be decreased when combined with Venetoclax.
Cobicistat Cobicistat The metabolism of Theophylline can be decreased when combined with Cobicistat.
Midodrine Midodrine The risk or severity of adverse effects can be increased when Midodrine is combined with Theophylline.
Selexipag Selexipag The metabolism of Selexipag can be decreased when combined with Theophylline.
Obeticholic Acid Obeticholic Acid The risk or severity of adverse effects can be increased when Obeticholic acid is combined with Theophylline.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Theophylline can be decreased when combined with Diphenhydramine.
Rucaparib Rucaparib The metabolism of Theophylline can be decreased when combined with Rucaparib.
Ribociclib Ribociclib The metabolism of Theophylline can be decreased when combined with Ribociclib.
Brigatinib Brigatinib The metabolism of Theophylline can be increased when combined with Brigatinib.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Theophylline can be decreased when combined with Doxepin.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Theophylline.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Theophylline.
Deflazacort Deflazacort The metabolism of Theophylline can be increased when combined with Deflazacort.
Safinamide Safinamide The metabolism of Theophylline can be decreased when combined with Safinamide.
Sarilumab Injection Sarilumab Injection The metabolism of Theophylline can be increased when combined with Sarilumab.
Midostaurin Midostaurin The metabolism of Theophylline can be increased when combined with Midostaurin.
Enasidenib Enasidenib The metabolism of Theophylline can be increased when combined with Enasidenib.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Theophylline can be increased when combined with Fosaprepitant.
Delafloxacin Delafloxacin The metabolism of Theophylline can be decreased when combined with Delafloxacin.
Acalabrutinib Acalabrutinib The metabolism of Theophylline can be decreased when combined with Acalabrutinib.
Letermovir Letermovir The metabolism of Theophylline can be decreased when combined with Letermovir.
Tetrabenazine Tetrabenazine The metabolism of Theophylline can be decreased when combined with Tetrabenazine.
Buprenorphine Injection Buprenorphine Injection The metabolism of Theophylline can be decreased when combined with Buprenorphine.
Apalutamide Apalutamide The metabolism of Theophylline can be increased when combined with Apalutamide.
Fostamatinib Fostamatinib The metabolism of Theophylline can be decreased when combined with Fostamatinib.
Avatrombopag Avatrombopag The metabolism of Theophylline can be increased when combined with Avatrombopag.
Lofexidine Lofexidine The metabolism of Theophylline can be decreased when combined with Lofexidine.
Eliglustat Eliglustat The metabolism of Theophylline can be decreased when combined with Eliglustat.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Theophylline.
Binimetinib Binimetinib The metabolism of Binimetinib can be decreased when combined with Theophylline.
Ivosidenib Ivosidenib The metabolism of Theophylline can be increased when combined with Ivosidenib.
Elagolix Elagolix The metabolism of Theophylline can be decreased when combined with Elagolix.
Tafenoquine Tafenoquine The metabolism of Theophylline can be decreased when combined with Tafenoquine.
Cannabidiol Cannabidiol The metabolism of Theophylline can be decreased when combined with Cannabidiol.
Dacomitinib Dacomitinib The metabolism of Theophylline can be decreased when combined with Dacomitinib.
Duvelisib Duvelisib The metabolism of Theophylline can be decreased when combined with Duvelisib.
Stiripentol Stiripentol The metabolism of Theophylline can be decreased when combined with Stiripentol.
Gilteritinib Gilteritinib The metabolism of Theophylline can be decreased when combined with Gilteritinib.
Glasdegib Glasdegib The metabolism of Glasdegib can be decreased when combined with Theophylline.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Theophylline.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Theophylline can be increased when combined with Paclitaxel.
Rifamycin Rifamycin The metabolism of Theophylline can be increased when combined with Rifamycin.
Prucalopride Prucalopride The metabolism of Theophylline can be decreased when combined with Prucalopride.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Theophylline can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be decreased when combined with Theophylline.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Acyclovir can be decreased when combined with Theophylline.
Alpelisib Alpelisib The metabolism of Theophylline can be increased when combined with Alpelisib.
Brexanolone Injection Brexanolone Injection Brexanolone may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Triclabendazole Triclabendazole The metabolism of Theophylline can be decreased when combined with Triclabendazole.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Theophylline.
Pitolisant Pitolisant The serum concentration of Theophylline can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib The metabolism of Theophylline can be decreased when combined with Fedratinib.
Lefamulin Lefamulin The serum concentration of Theophylline can be increased when it is combined with Lefamulin.
Phenytoin Injection Phenytoin Injection The serum concentration of Theophylline can be decreased when it is combined with Phenytoin.
Fosphenytoin Injection Fosphenytoin Injection The serum concentration of Theophylline can be decreased when it is combined with Fosphenytoin.
Voxelotor Voxelotor The serum concentration of Theophylline can be increased when it is combined with Voxelotor.
Tazemetostat Tazemetostat The metabolism of Theophylline can be decreased when combined with Tazemetostat.
Cenobamate Cenobamate The serum concentration of Theophylline can be decreased when it is combined with Cenobamate.
Ozanimod Ozanimod The metabolism of Ozanimod can be decreased when combined with Theophylline.
Selumetinib Selumetinib The metabolism of Selumetinib can be decreased when combined with Theophylline.
Tucatinib Tucatinib The metabolism of Tucatinib can be decreased when combined with Theophylline.
Selpercatinib Selpercatinib The serum concentration of Theophylline can be increased when it is combined with Selpercatinib.
Capmatinib Capmatinib The serum concentration of Theophylline can be increased when it is combined with Capmatinib.
Fenfluramine Fenfluramine The metabolism of Theophylline can be decreased when combined with Fenfluramine.
Octreotide Octreotide The serum concentration of Theophylline can be increased when it is combined with Octreotide.
Pralsetinib Pralsetinib The metabolism of Theophylline can be increased when combined with Pralsetinib.
Opicapone Opicapone The metabolism of Theophylline can be decreased when combined with Opicapone.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Theophylline can be decreased when it is combined with Satralizumab.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives Drospirenone may decrease the excretion rate of Theophylline which could result in a higher serum level.
Viloxazine Viloxazine The metabolism of Theophylline can be decreased when combined with Viloxazine.
Vitamin E (Alpha-Tocopherol) Vitamin E (Alpha-Tocopherol) The metabolism of Theophylline can be increased when combined with Vitamin E.
Mefenamic Acid Mefenamic Acid The metabolism of Theophylline can be decreased when combined with Mefenamic acid.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Theophylline.
Trazodone Trazodone The metabolism of Theophylline can be decreased when combined with Trazodone.
Sucralfate Sucralfate Sucralfate can cause a decrease in the absorption of Theophylline resulting in a reduced serum concentration and potentially a decrease in efficacy.
Hydroxyurea Hydroxyurea The metabolism of Theophylline can be decreased when combined with Hydroxyurea.
Methotrexate Injection Methotrexate Injection The serum concentration of Theophylline can be increased when it is combined with Methotrexate.
Primidone Primidone The metabolism of Theophylline can be increased when combined with Primidone.
Methsuximide Methsuximide Methsuximide may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Diethylpropion Diethylpropion The risk or severity of adverse effects can be increased when Diethylpropion is combined with Theophylline.
Chlorpromazine Chlorpromazine The metabolism of Theophylline can be decreased when combined with Chlorpromazine.
Diazepam Diazepam The metabolism of Theophylline can be decreased when combined with Diazepam.
Oxazepam Oxazepam The therapeutic efficacy of Oxazepam can be decreased when used in combination with Theophylline.
Flurazepam Flurazepam The metabolism of Flurazepam can be decreased when combined with Theophylline.
Clorazepate Clorazepate The therapeutic efficacy of Clorazepic acid can be decreased when used in combination with Theophylline.
Lorazepam Lorazepam The metabolism of Theophylline can be decreased when combined with Lorazepam.
Carmustine Carmustine The metabolism of Theophylline can be decreased when combined with Carmustine.
Codeine Codeine The metabolism of Codeine can be decreased when combined with Theophylline.
Chlordiazepoxide Chlordiazepoxide The therapeutic efficacy of Chlordiazepoxide can be decreased when used in combination with Theophylline.
Bromocriptine Bromocriptine The metabolism of Bromocriptine can be decreased when combined with Theophylline.
Metaproterenol Metaproterenol The risk or severity of adverse effects can be increased when Orciprenaline is combined with Theophylline.
Tranylcypromine Tranylcypromine The metabolism of Theophylline can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Theophylline can be decreased when combined with Phenelzine.
Tetracycline Tetracycline The metabolism of Theophylline can be decreased when combined with Tetracycline.
Prochlorperazine Prochlorperazine The metabolism of Theophylline can be decreased when combined with Prochlorperazine.
Thioridazine Thioridazine The metabolism of Theophylline can be decreased when combined with Thioridazine.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be decreased when combined with Theophylline.
Dapsone Dapsone The metabolism of Theophylline can be decreased when combined with Dapsone.
Sulfadiazine Sulfadiazine The metabolism of Sulfadiazine can be decreased when combined with Theophylline.
Oxycodone Oxycodone The metabolism of Oxycodone can be decreased when combined with Theophylline.
Methadone Methadone The metabolism of Theophylline can be decreased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Theophylline can be decreased when combined with Oxybutynin.
Benztropine Benztropine The metabolism of Theophylline can be decreased when combined with Benzatropine.
Maprotiline Maprotiline The metabolism of Theophylline can be decreased when combined with Maprotiline.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Theophylline.
Orphenadrine Orphenadrine The metabolism of Theophylline can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Theophylline can be decreased when combined with Perphenazine.
Azathioprine Azathioprine The metabolism of Azathioprine can be decreased when combined with Theophylline.
Fluphenazine Fluphenazine The metabolism of Theophylline can be decreased when combined with Fluphenazine.
Phentermine Phentermine The metabolism of Theophylline can be decreased when combined with Phentermine.
Amoxapine Amoxapine The metabolism of Amoxapine can be decreased when combined with Theophylline.
Hydrocortisone Hydrocortisone The metabolism of Theophylline can be increased when combined with Hydrocortisone.
Doxorubicin Doxorubicin The metabolism of Theophylline can be decreased when combined with Doxorubicin.
Carbamazepine Carbamazepine The serum concentration of Theophylline can be decreased when it is combined with Carbamazepine.
Clonidine Clonidine The metabolism of Clonidine can be decreased when combined with Theophylline.
Hydralazine Hydralazine The metabolism of Theophylline can be decreased when combined with Hydralazine.
Cimetidine Cimetidine The metabolism of Theophylline can be decreased when combined with Cimetidine.
Warfarin Warfarin The metabolism of Theophylline can be increased when combined with Warfarin.
Clonazepam Clonazepam The metabolism of Clonazepam can be decreased when combined with Theophylline.
Loperamide Loperamide The metabolism of Theophylline can be decreased when combined with Loperamide.
Promethazine Promethazine The metabolism of Theophylline can be decreased when combined with Promethazine.
Daunorubicin Daunorubicin The metabolism of Theophylline can be decreased when combined with Daunorubicin.
Griseofulvin Griseofulvin The metabolism of Theophylline can be increased when combined with Griseofulvin.
Chloroquine Chloroquine The metabolism of Theophylline can be decreased when combined with Chloroquine.
Quinine Quinine The serum concentration of Theophylline can be increased when it is combined with Quinine.
Ethosuximide Ethosuximide The metabolism of Theophylline can be decreased when combined with Ethosuximide.
Calcitriol Calcitriol The metabolism of Theophylline can be increased when combined with Calcitriol.
Triamterene Triamterene The metabolism of Triamterene can be decreased when combined with Theophylline.
Sulfinpyrazone Sulfinpyrazone The metabolism of Theophylline can be increased when combined with Sulfinpyrazone.
Clindamycin Injection Clindamycin Injection The metabolism of Theophylline can be decreased when combined with Clindamycin.
Secobarbital Secobarbital The metabolism of Theophylline can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Theophylline can be decreased when combined with Desipramine.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Theophylline.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Theophylline.
Probenecid Probenecid The serum concentration of Theophylline can be increased when it is combined with Probenecid.
Quinidine Quinidine The serum concentration of Theophylline can be increased when it is combined with Quinidine.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Theophylline.
Isoniazid Isoniazid The serum concentration of Theophylline can be increased when it is combined with Isoniazid.
Rifampin Rifampin The metabolism of Theophylline can be increased when combined with Rifampicin.
Disopyramide Disopyramide The metabolism of Disopyramide can be decreased when combined with Theophylline.
Valproic Acid Valproic Acid The metabolism of Theophylline can be decreased when combined with Valproic acid.
Tamoxifen Tamoxifen The metabolism of Theophylline can be increased when combined with Tamoxifen.
Butabarbital Butabarbital The serum concentration of Theophylline can be decreased when it is combined with Butabarbital.
Levothyroxine Levothyroxine Levothyroxine may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Liothyronine Liothyronine Liothyronine may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Methimazole Methimazole The excretion of Theophylline can be decreased when combined with Methimazole.
Propylthiouracil Propylthiouracil Propylthiouracil may decrease the excretion rate of Theophylline which could result in a higher serum level.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Theophylline.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Theophylline.
Cyclobenzaprine Cyclobenzaprine The metabolism of Cyclobenzaprine can be decreased when combined with Theophylline.
Niacin Niacin The metabolism of Theophylline can be decreased when combined with Niacin.
Clemastine Clemastine The metabolism of Theophylline can be decreased when combined with Clemastine.
Chlorpheniramine Chlorpheniramine The metabolism of Theophylline can be decreased when combined with Chlorpheniramine.
Meclizine Meclizine The metabolism of Theophylline can be decreased when combined with Meclizine.
Chlorzoxazone Chlorzoxazone The metabolism of Chlorzoxazone can be decreased when combined with Theophylline.
Danazol Danazol The metabolism of Theophylline can be decreased when combined with Danazol.
Disulfiram Disulfiram The serum concentration of Theophylline can be increased when it is combined with Disulfiram.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The metabolism of Propranolol can be decreased when combined with Theophylline.
Pseudoephedrine Pseudoephedrine The risk or severity of adverse effects can be increased when Pseudoephedrine is combined with Theophylline.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Theophylline.
Spironolactone Spironolactone The metabolism of Theophylline can be decreased when combined with Spironolactone.
Amphotericin B Injection Amphotericin B Injection The metabolism of Theophylline can be decreased when combined with Amphotericin B.
Nadolol Nadolol The metabolism of Theophylline can be decreased when combined with Nadolol.
Allopurinol Allopurinol The serum concentration of Theophylline can be increased when it is combined with Allopurinol.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Theophylline.
Colchicine Colchicine The metabolism of Theophylline can be increased when combined with Colchicine.
Cephalexin Cephalexin The metabolism of Theophylline can be decreased when combined with Cephalexin.
Dacarbazine Dacarbazine The metabolism of Dacarbazine can be decreased when combined with Theophylline.
Acetazolamide Acetazolamide The metabolism of Theophylline can be decreased when combined with Acetazolamide.
Bacillus Calmette-Guerin (BCG) Vaccine Bacillus Calmette-Guerin (BCG) Vaccine The serum concentration of Theophylline can be increased when it is combined with Bacillus calmette-guerin substrain tice live antigen.
Ketoconazole Ketoconazole The metabolism of Theophylline can be decreased when combined with Ketoconazole.
Isoxsuprine Isoxsuprine The risk or severity of adverse effects can be increased when Isoxsuprine is combined with Theophylline.
Vinblastine Vinblastine The metabolism of Theophylline can be increased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Theophylline can be decreased when combined with Metoprolol.
Hydroxyzine Hydroxyzine The metabolism of Theophylline can be decreased when combined with Hydroxyzine.
Thiothixene Thiothixene The metabolism of Thiothixene can be decreased when combined with Theophylline.
Alprazolam Alprazolam The therapeutic efficacy of Alprazolam can be decreased when used in combination with Theophylline.
Temazepam Temazepam The therapeutic efficacy of Temazepam can be decreased when used in combination with Theophylline.
Triazolam Triazolam The therapeutic efficacy of Triazolam can be decreased when used in combination with Theophylline.
Trimethoprim Trimethoprim The metabolism of Theophylline can be decreased when combined with Trimethoprim.
Diltiazem Diltiazem The metabolism of Diltiazem can be decreased when combined with Theophylline.
Nifedipine Nifedipine The metabolism of Theophylline can be increased when combined with Nifedipine.
Timolol Timolol The metabolism of Theophylline can be decreased when combined with Timolol.
Verapamil Verapamil The serum concentration of Theophylline can be increased when it is combined with Verapamil.
Atenolol Atenolol The metabolism of Theophylline can be decreased when combined with Atenolol.
Pindolol Pindolol The metabolism of Theophylline can be decreased when combined with Pindolol.
Piroxicam Piroxicam The metabolism of Theophylline can be decreased when combined with Piroxicam.
Streptozocin Streptozocin The metabolism of Theophylline can be increased when combined with Streptozocin.
Etoposide Etoposide The metabolism of Theophylline can be increased when combined with Etoposide.
Glyburide Glyburide The metabolism of Theophylline can be decreased when combined with Glyburide.
Dicloxacillin Dicloxacillin The metabolism of Theophylline can be increased when combined with Dicloxacillin.
Nafcillin Injection Nafcillin Injection The metabolism of Theophylline can be increased when combined with Nafcillin.
Pentoxifylline Pentoxifylline The serum concentration of Theophylline can be increased when it is combined with Pentoxifylline.
Pentamidine Injection Pentamidine Injection The metabolism of Theophylline can be decreased when combined with Pentamidine.
Labetalol Labetalol The metabolism of Theophylline can be decreased when combined with Labetalol.
Gemfibrozil Gemfibrozil The metabolism of Theophylline can be decreased when combined with Gemfibrozil.
Guanabenz Guanabenz The metabolism of Guanabenz can be decreased when combined with Theophylline.
Ketoprofen Ketoprofen The metabolism of Theophylline can be decreased when combined with Ketoprofen.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Theophylline.
Amiodarone Amiodarone The metabolism of Amiodarone can be decreased when combined with Theophylline.
Buspirone Buspirone The metabolism of Buspirone can be decreased when combined with Theophylline.
Lovastatin Lovastatin The metabolism of Theophylline can be decreased when combined with Lovastatin.
Ciprofloxacin Ciprofloxacin The serum concentration of Theophylline can be increased when it is combined with Ciprofloxacin.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Theophylline.
Fluoxetine Fluoxetine The serum concentration of Theophylline can be increased when it is combined with Fluoxetine.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The metabolism of Theophylline can be decreased when combined with Interferon alfa-2b.
Clozapine Clozapine The metabolism of Theophylline can be decreased when combined with Clozapine.
Estazolam Estazolam The therapeutic efficacy of Estazolam can be decreased when used in combination with Theophylline.
Idarubicin Idarubicin The metabolism of Theophylline can be decreased when combined with Idarubicin.
Ofloxacin Ofloxacin The metabolism of Theophylline can be decreased when combined with Ofloxacin.
Clarithromycin Clarithromycin The therapeutic efficacy of Clarithromycin can be decreased when used in combination with Theophylline.
Felodipine Felodipine The metabolism of Felodipine can be decreased when combined with Theophylline.
Nabumetone Nabumetone The metabolism of Nabumetone can be decreased when combined with Theophylline.
Simvastatin Simvastatin The metabolism of Theophylline can be decreased when combined with Simvastatin.
Teniposide Injection Teniposide Injection The metabolism of Theophylline can be decreased when combined with Teniposide.
Itraconazole Itraconazole The metabolism of Theophylline can be decreased when combined with Itraconazole.
Rifabutin Rifabutin The metabolism of Theophylline can be increased when combined with Rifabutin.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Theophylline.
Bisoprolol Bisoprolol The risk or severity of adverse effects can be increased when Bisoprolol is combined with Theophylline.
Zolpidem Zolpidem The metabolism of Zolpidem can be decreased when combined with Theophylline.
Doxazosin Doxazosin The metabolism of Theophylline can be decreased when combined with Doxazosin.
Isradipine Isradipine The metabolism of Isradipine can be decreased when combined with Theophylline.
Omeprazole Omeprazole The metabolism of Theophylline can be increased when combined with Omeprazole.
Cisapride Cisapride The metabolism of Cisapride can be decreased when combined with Theophylline.
Gabapentin Gabapentin The therapeutic efficacy of Gabapentin can be decreased when used in combination with Theophylline.
Fluvastatin Fluvastatin The metabolism of Theophylline can be decreased when combined with Fluvastatin.
Venlafaxine Venlafaxine The metabolism of Theophylline can be decreased when combined with Venlafaxine.
Famciclovir Famciclovir The metabolism of Theophylline can be decreased when combined with Famciclovir.
Fluvoxamine Fluvoxamine The metabolism of Theophylline can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Theophylline can be decreased when combined with Nefazodone.
Lamotrigine Lamotrigine Lamotrigine may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Losartan Losartan The metabolism of Theophylline can be decreased when combined with Losartan.
Tramadol Tramadol The metabolism of Theophylline can be decreased when combined with Tramadol.
Vinorelbine Injection Vinorelbine Injection The metabolism of Theophylline can be decreased when combined with Vinorelbine.
Lansoprazole Lansoprazole Lansoprazole may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Ifosfamide Injection Ifosfamide Injection The metabolism of Theophylline can be increased when combined with Ifosfamide.
Nicardipine Nicardipine The metabolism of Theophylline can be decreased when combined with Nicardipine.
Bupropion Bupropion The risk or severity of seizure can be increased when Bupropion is combined with Theophylline.
Ticlopidine Ticlopidine The metabolism of Theophylline can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir The metabolism of Theophylline can be decreased when combined with Saquinavir.
Riluzole Riluzole Riluzole may increase the excretion rate of Theophylline which could result in a lower serum level and potentially a reduction in efficacy.
Anastrozole Anastrozole The metabolism of Anastrozole can be decreased when combined with Theophylline.
Ritonavir Ritonavir The serum concentration of Theophylline can be decreased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Theophylline can be decreased when combined with Docetaxel.
Clomipramine Clomipramine The metabolism of Theophylline can be decreased when combined with Clomipramine.
Zafirlukast Zafirlukast The serum concentration of Zafirlukast can be decreased when it is combined with Theophylline.
Mirtazapine Mirtazapine The metabolism of Theophylline can be decreased when combined with Mirtazapine.
Topiramate Topiramate The metabolism of Theophylline can be increased when combined with Topiramate.
Zileuton Zileuton The serum concentration of Theophylline can be increased when it is combined with Zileuton.
Insulin Lispro Injection Insulin Lispro Injection The metabolism of Theophylline can be increased when combined with Insulin lispro.
Donepezil Donepezil The metabolism of Donepezil can be decreased when combined with Theophylline.
Nelfinavir Nelfinavir The metabolism of Theophylline can be decreased when combined with Nelfinavir.
Azithromycin Azithromycin The metabolism of Theophylline can be decreased when combined with Azithromycin.
Loratadine Loratadine The metabolism of Theophylline can be decreased when combined with Loratadine.
Carvedilol Carvedilol The metabolism of Carvedilol can be decreased when combined with Theophylline.
Nilutamide Nilutamide The metabolism of Theophylline can be decreased when combined with Nilutamide.
Flutamide Flutamide The metabolism of Flutamide can be decreased when combined with Theophylline.
Selegiline Selegiline The metabolism of Theophylline can be decreased when combined with Selegiline.
Bicalutamide Bicalutamide The metabolism of Theophylline can be decreased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Theophylline can be decreased when combined with Sertraline.
Propafenone Propafenone The serum concentration of Theophylline can be increased when it is combined with Propafenone.
Raloxifene Raloxifene The metabolism of Theophylline can be decreased when combined with Raloxifene.
Irbesartan Irbesartan The metabolism of Theophylline can be decreased when combined with Irbesartan.
Tamsulosin Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Theophylline.
Quetiapine Quetiapine The metabolism of Quetiapine can be decreased when combined with Theophylline.
Cetirizine Cetirizine The serum concentration of Cetirizine can be increased when it is combined with Theophylline.
Paroxetine Paroxetine The serum concentration of Theophylline can be increased when it is combined with Paroxetine.
Citalopram Citalopram The metabolism of Theophylline can be decreased when combined with Citalopram.
Efavirenz Efavirenz The metabolism of Theophylline can be increased when combined with Efavirenz.
Pioglitazone Pioglitazone The metabolism of Theophylline can be decreased when combined with Pioglitazone.
Celecoxib Celecoxib The metabolism of Theophylline can be decreased when combined with Celecoxib.
Rosiglitazone Rosiglitazone The metabolism of Theophylline can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Theophylline.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Theophylline.
Galantamine Galantamine The metabolism of Galantamine can be decreased when combined with Theophylline.
Levetiracetam Levetiracetam The therapeutic efficacy of Levetiracetam can be decreased when used in combination with Theophylline.
Rabeprazole Rabeprazole The metabolism of Theophylline can be decreased when combined with Rabeprazole.
Terbinafine Terbinafine The metabolism of Theophylline can be decreased when combined with Terbinafine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists