Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Aging and Cellular Health Ingredients & Drug Interactions

by Jocko Fuel

Aging and Cellular Health label
See full label image
Other (e.g. Tea Bag) Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Aging and Cellular Health against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Aging and Cellular Health is a dietary supplement by Jocko Fuel with 5 active ingredients. Its ingredients are commonly taken for energy and reduced fatigue, focus and mental alertness, mood support.Based on those ingredients, 382 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Theacrine, Wasabi Extract, Cuprous Niacin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Aging and Cellular Health by Jocko Fuel

Ask about any prescription or over-the-counter medication and we check it for interactions with Aging and Cellular Health by Jocko Fuel — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Aging and Cellular Health by Jocko Fuel

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 5 active ingredients.
  • “NAD3 Proprietary Blend” is a proprietary blend — the label gives one combined amount (312 mg) without saying how much of each component you get.

This product contains 5 active ingredients working together on aging and cellular health. Theacrine is a caffeine-like compound; Wasabi Extract provides concentrated compounds from wasabi root; Cuprous Niacin supplies copper bound to niacin; Pyrroloquinoline Quinone Disodium Salt (PQQ) is a cofactor involved in cellular energy; and Yuth is a proprietary blend ingredient.

The product also includes a NAD3 Proprietary Blend — we'd need to see its label to know which NAD-supporting ingredients it contains. Inactive ingredients like dicalcium phosphate, hydroxypropyl methylcellulose, and magnesium stearate are fillers and binders that make up the rest of the formula.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Anti-aging and cellular health support.
  • We looked for evidence on: Cardiovascular disease (CVD), Cognitive function, Copper deficiency, Fatigue, Mental alertness, Muscle strength — and 4 related terms.
  • The strongest evidence on file: Copper is rated "Likely Effective" for Copper deficiency (Natural Medicines).
  • Also on file: Copper is rated "Insufficient Reliable Evidence To Rate" for Osteoporosis, Cardiovascular disease (CVD).
  • Also on file: Theacrine is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Fatigue, Mental alertness, Muscle strength.

The evidence supporting these ingredients is limited. For theacrine, we don't have reliable data yet on whether it boosts athletic performance, brain function, fatigue, alertness, or muscle strength — effectiveness hasn't been established in our data.

Wasabi extract likewise lacks solid evidence for osteoporosis, heart disease, chronic fatigue, indigestion, or fatigue relief. Cuprous niacin is likely effective for copper deficiency, but for Alzheimer's disease it's rated possibly ineffective; other uses like acne or chemotherapy-related anemia don't have enough evidence.

We hold no effectiveness ratings for Pyrroloquinoline Quinone Disodium Salt or Yuth.

The evidence, ingredient by ingredient Theacrine Wasabi Copper

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Theacrine is generally well tolerated in short-term studies, but long-term safety isn't established — if you're taking it regularly, that's something to keep an eye on. Wasabi extract is safe in food amounts, but supplement-strength doses haven't been well studied.

A small trial using 1000–2000 mg daily for 4 weeks reported a couple of cases of protein in urine, one case of mildly elevated liver enzymes, and one case of ketone bodies in urine; these are uncommon but worth knowing. Copper is needed in pregnancy and lactation, but stay within recommended amounts and avoid high-dose supplements without medical guidance — excess copper can be toxic.

Rarely, copper can cause contact dermatitis. No adverse effects are documented for theacrine, and we hold no safety data for Pyrroloquinoline Quinone Disodium Salt or Yuth.

Side effects, ingredient by ingredient Theacrine Wasabi Copper

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Copper, Theacrine, Wasabi.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 382 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you're on blood thinners or antiplatelet drugs like warfarin or aspirin (wasabi extract, Moderate); CNS depressants like sedatives, sleep aids, or opioid pain relievers (theacrine, Moderate); penicillamine for Wilson's disease (cuprous niacin, Moderate); or birth control pills (cuprous niacin, Minor). No interactions are documented for the two ingredients we could not check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood thinners, sedatives, penicillamine for Wilson's disease, or birth control pills, check with your pharmacist before starting this product. Theacrine and wasabi extract interactions haven't been reported in people, but the theoretical risks are real enough to verify.

Short-term use of the documented ingredients appears generally well tolerated, but long-term safety isn't proven. Talk to your pharmacist about your full medication list — that's the only way to know if this product is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Aging and Cellular Health, straight from the product label.

Brand Jocko Fuel
Net contents 30 Pack(s)
Market status On market
Date entered into DSLD Sep 25, 2023
DSLD ID 300512
Product type Other Combinations
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Aging and Cellular Health by Jocko Fuel, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Packet(s)
Maximum serving Sizes:
1 Packet(s)
Servings per container
30
IngredientAmount% DV
Theacrine0 NP--
NAD3 Proprietary Blend312 mg--
Wasabi Extract0 NP--
Cuprous Niacin0 NP--
Pyrroloquinoline Quinone Disodium Salt10 mg--
Yuth3 mg--

Other ingredients: Dicalcium Phosphate, Hydroxypropyl Methylcellulose, Water, Purified, Chlorophyll, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Anti-aging Stress supporting adaptogen blend Supports cardiovascular biomarkers Supports mitochondrial health

Formula

Essential vitamin & nutrient complex

NAD3 Yuth

Aging and cellular health NAD3 PQQ Yuth

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take the contents of one packet daily preferably with a meal or as recommended by a physician.

Precautions

Warning: consult a physician or licensed qualified health care professional before using this product if you are pregnant, nursing, taking any medications, including blood thinners, planning any medical or surgical procedure or have any medical condition.

Discontinue immediately if any side effects occur.

Not for use by individuals under the age of 18 years. Keep out of the reach of children.

Storage

Store product at room temperature. Do not expose to excessive heat or moisture.

General Statements

Daily matrix

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Aging and Cellular Health by Jocko Fuel label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Aging and Cellular Health label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Aging and Cellular Health by Jocko Fuel

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Packet(s) Dosage formOther (e.g. Tea Bag) Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

NAD3 Proprietary Blend

312 mg per serving

Pyrroloquinoline Quinone Disodium Salt

10 mg per serving

Yuth

3 mg per serving Form: Spermidine hydrochloride

Other (inactive) ingredients: Dicalcium Phosphate, Hydroxypropyl Methylcellulose, Water, Purified, Chlorophyll, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Aging and Cellular Health by Jocko Fuel Drug Interactions

Want to check YOUR meds against Aging and Cellular Health?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
382Drugs
352 Moderate 30 Minor

Ingredients driving the most interactions

Theacrine 248
Wasabi Extract 122
Cuprous Niacin 31

Individual Drug Interactions

The ingredients in Aging and Cellular Health interact with 382 drugs. Click any drug to see the details.

3 of the 5 ingredients in Aging and Cellular Health interact with drugs. Each result below shows which ingredient is responsible. Theacrine Wasabi Extract Cuprous Niacin

Each ingredient & the kinds of drugs it affects

For each ingredient in Aging and Cellular Health with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Theacrine1 drug type · 248 drugs

Cns Depressants

Theoretically, theacrine might alter the effects of CNS depressants.
Animal research shows that low doses of theacrine have sedating effects, whereas high doses might have stimulant effects. Depending on the dose of theacrine used, it might increase or decrease the effects of CNS depressants. However, these effects have not yet been reported in humans.

Likelihood Possible Evidence D
Theacrine full monograph & interactions

Wasabi Extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, wasabi might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
In vitro research shows that 6-(methylsulfinyl) hexyl isothiocyanate, a constituent of wasabi, inhibits platelet aggregation.

Likelihood Possible Evidence D
Wasabi Extract full monograph & interactions

Cuprous Niacin2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
Cuprous Niacin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Aging and Cellular Health, from the product label.

Jocko Fuel

See all Jocko Fuel products
Name
Jocko Fuel, LLC
City
Jay
State
ME
ZipCode
04239
Phone Number
1-888-858-1416
Web Address
jockofuel.com
Pharmacist Counseling Corner

Aging and Cellular Health by Jocko Fuel: Common Questions

Does Aging and Cellular Health by Jocko Fuel interact with any medications?
Yes. Based on its ingredients, Aging and Cellular Health has a known interaction with 382 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Aging and Cellular Health contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant?
Theacrine is not recommended in pregnancy because there isn't enough safety data. Wasabi extract and Pyrroloquinoline Quinone Disodium Salt also lack pregnancy safety data, so you'd need to talk with your doctor. Cuprous niacin is likely safe at recommended amounts, but one rating calls it possibly unsafe, so don't start this without checking with your healthcare provider first.
Can I take this if I'm breastfeeding?
Theacrine is not recommended while breastfeeding due to insufficient safety data. Wasabi extract and the other ingredients either lack breastfeeding data or haven't been studied well enough. Cuprous niacin is rated likely safe at normal levels. Talk with your doctor or pharmacist before using this product — they can give you personalized advice for your situation.
Does this actually work for anti-aging?
The evidence isn't established in the data we hold. Theacrine, wasabi, and PQQ all lack reliable evidence for aging-related claims. Cuprous niacin does have solid evidence for treating copper deficiency, but no proven benefit for anti-aging. The ingredients may have potential, but solid proof in people isn't available yet.
What is theacrine, and what does it do?
Theacrine is a caffeine-like compound. We don't yet have reliable evidence that it boosts athletic performance, mental sharpness, energy, or muscle strength — those effects haven't been proven in our data. Short-term use appears generally well tolerated, though long-term safety is unknown.
Why is copper in this product?
Cuprous niacin is a copper supplement. Copper is an essential mineral your body needs, and this form is likely effective for treating copper deficiency. However, too much copper can be toxic, so stick to the dose on the label and avoid high-dose supplements without medical guidance.
What are the side effects of wasabi extract?
In a small trial at 1000–2000 mg daily for 4 weeks, a few participants developed protein in their urine, mildly elevated liver enzymes, or ketone bodies in urine. These are uncommon findings, but they show that concentrated wasabi doses need caution. Food-level amounts are considered safe; supplement doses are less well studied.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Aging and Cellular Health is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Aging and Cellular Health label
Go deeper

The Full Monographs Behind Aging and Cellular Health’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Theacrine

Interacts with 248 drugs

Theacrine is a caffeine-like compound found naturally in certain tea plants and is sold in supplements for energy, focus, and mood. Early human studies suggest it may give a stimulant-like b...

Read the full Theacrine monograph → Herb & supplement monograph

Wasabi

Interacts with 122 drugs

Wasabi is best known as the pungent green condiment served with sushi, made from a Japanese plant in the cabbage family. Its natural compounds (isothiocyanates) show antimicrobial and antiox...

Read the full Wasabi monograph → Herb & supplement monograph

Copper

Interacts with 31 drugs

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes work. Most people get enough copper from fo...

Read the full Copper monograph →
Sources

Sources & How We Checked

Aging and Cellular Health's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Theacrine 1 reference
  1. Xu JK, Kurihara H, Zhao L, Yao XS. Theacrine, a special purine alkaloid with sedative and hypnotic properties from Cammelia assamica var. kucha in mice. J Asian Nat Prod Res 2007;9(6-8):665-72.

See these in context on the Theacrine monograph →

Wasabi 2 references
  1. Morimitsu, Y., Hayashi, K., Nakagawa, Y., Fujii, H., Horio, F., Uchida, K., and Osawa, T. Antiplatelet and anticancer isothiocyanates in Japanese domestic horseradish, Wasabi. Mech Ageing Dev 2000;116(2-3):125-134. PubMed
  2. Nakajima R, Kanou M, Tokushima M, Iwama Y, Yamana K. Oral administration of 6-methylsulfinylhexyl isothiocyanate extracted from wasabi is safe and improves the fatigue and sleep of healthy volunteers. Biopsychosoc Med 2023;17(1):30. PubMed

See these in context on the Wasabi monograph →

Copper 11 references
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
  3. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  4. Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
  7. Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
  8. Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
  9. Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
  10. Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
  11. Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed

See these in context on the Copper monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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