Ajuna Chhal / Bark Ingredients & Drug Interactions
by Vedic Herbs
What is this page for?
First and foremost: checking Ajuna Chhal / Bark against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Ajuna Chhal / Bark is a dietary supplement by Vedic Herbs with 1 active ingredient. Its ingredients are commonly taken for heart health and circulation, digestive problems (constipation, diarrhea), cholesterol support.Based on those ingredients, 933 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Arjuna. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Ajuna Chhal / Bark by Vedic Herbs
Ask about any prescription or over-the-counter medication and we check it for interactions with Ajuna Chhal / Bark by Vedic Herbs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Ajuna Chhal / Bark by Vedic Herbs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Arjuna bark powder (Terminalia arjuna). Arjuna is a traditional Ayurvedic herb used historically to support heart and cardiovascular health.
There are no inactive fillers or other ingredients listed.
Does it work?
Not established
The evidence we hold shows insufficient reliable data to rate Arjuna for any of its traditional uses — obesity, high cholesterol, high blood pressure, or angina. That means studies either don't exist yet or aren't strong enough to confirm whether it actually works for these conditions.
If you're looking at this for heart or metabolic support, talk with your doctor about whether the evidence supports it for your specific situation.
How safe is it?
Some data gaps
Arjuna is generally well tolerated in short-term studies, but long-term safety data is thin and quality varies between products. The safety data advises against use during pregnancy and breastfeeding — there isn't enough information to know whether it's safe for you or your baby at those times.
Talk with your doctor or pharmacist if you're pregnant, nursing, or planning either.
Meds to double-check
Moderate interaction found
Before taking this product, check whether you're on blood thinners or antiplatelet drugs — Arjuna may increase bleeding risk. Also double-check any medications your liver processes, including heart drugs, antidepressants, and statins.
If you take diabetes medications or the muscle relaxant chlorzoxazone or heartburn medication omeprazole, verify those too with your pharmacist.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.
Arjuna might appeal to you if you're interested in traditional Ayurvedic support for heart health, but the scientific evidence on whether it works is weak. More importantly, this herb interacts with a large number of medications by slowing how your body clears them — blood thinners, diabetes drugs, and many others.
Check your exact medications with our tool before you start, and run it by your pharmacist or doctor first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Ajuna Chhal / Bark, straight from the product label.
| Brand | Vedic Herbs |
|---|---|
| Barcode (UPC) | 850049510295 |
| Net contents | 100 Gram(s); 3.52 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Aug 22, 2025 |
| DSLD ID | 336141 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Ajuna Chhal / Bark by Vedic Herbs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Arjuna | 3 Gram(s) | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Assisting the Indian tribal community
The Vedic Store Scan with mobile camera Follow us Facebook Instagram X YouTube Stay fit, stay healthy. Let's try some yoga Surya Namaskar Meditation Mula Bandha Navasana
Individual responses to Arjuna's potential benefits may vary.
For comments/feedback: [email protected] 1-612-88-VEDIC www.vedicjuices.com
FDA Statement of Identity
Dietary Supplement
Formulation
100% natural 100% original
No preservatives No artificial color, flavor Gluten free Non GMO
Purity guarantee process Sorted Washed Dried
Vegan 100% veg
Authentic premium quality
Food allergens: Does not contain - Fish, meat or milk.
Color variation may occur batch to batch due to natural ingredient & climatic variations, but the nutritional values remain constant. We source the finest quality from Indian farms & forests.
Brand IP Statement(s)
Vedic Herbs Your Health Matters
Formula
Terminalia arjuna/White Marudah
Arjuna contains various bioactive compounds, including triterpenoids, flavonoids, and tannins. Arjuna is valued for its cardioprotective properties and known to support - Healthy cholesterol levels. Healthy cardio-vascular function.
Suggested/Recommended/Usage/Directions
Direction for use: As a powder consume 3 grams mixed with honey/warm water or milk. Twice daily after meal.
Add healthy herbs to your daily routine, along with walking, meditation & yoga.
Arjuna can be used in various forms even as a part of traditional ayurvedic preparations as below - Powder Capsules or tablets Decoction (Kashayam) - Boil Arjuna bark, strain, and consume. Tea - Steep Arjuna powder in hot water for herbal tea. Tincture - Use a few drops in water.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Prior to using Arjuna or any supplement, it is advisable to consult with a healthcare provider, particularly if you have underlying health conditions or are taking medications.
"The oxygen absorber and silica gel in this packaging preserve product quality by absorbing excess oxygen and moisture. They are not meant for consumption and should be removed before consuming the contents."
Keep out of reach of children.
Storage
Store in a cool & dry place. Keep away from humidity & direct sun light.
Seals/Symbols
FSSAI (Food Safety and Standards Authority of India) Mfg. Lic No. 12223999000032
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Ajuna Chhal / Bark by Vedic Herbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Ajuna Chhal / Bark by Vedic Herbs
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Gram(s) Dosage formPowder Servings per container33 Amounts shown are per serving.
Arjuna
Interacts with933 drugs
Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes....
Arjuna monograph & interactionsAjuna Chhal / Bark by Vedic Herbs Drug Interactions
HelloPharmacist Interaction Report
Vedic Herbs Ajuna Chhal / Bark is a single-ingredient product containing Arjuna (Terminalia arjuna), and it does interact with medications.
The most serious concern is with blood thinners and antiplatelet drugs (Moderate severity). Lab research shows that Arjuna can slow down how your body breaks down these drugs, raising their levels in your blood and increasing your bleeding risk.
Read the full breakdown — every affected drug type, severity by severity
Arjuna also affects how your liver processes several other common medication types. It can increase levels of drugs metabolized by CYP2D6, CYP2C9, and CYP3A4 enzymes — meaning many heart medications, antidepressants, statins, and other drugs may stay in your system longer and work more strongly than intended.
Additionally, if you take diabetes medications, Arjuna may lower your blood sugar more than expected. Two specific drugs — chlorzoxazone (a muscle relaxant) and omeprazole (a heartburn medication) — have animal evidence of higher blood levels when combined with this product.
Altogether, these interactions span 922 individual medications. Use the medication checker on this page to verify your exact prescriptions and over-the-counter drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Ajuna Chhal / Bark?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Ajuna Chhal / Bark interact with 933 drugs. Click any drug to see the details.
1 of the 1 ingredient in Ajuna Chhal / Bark interact with drugs. Each result below shows which ingredient is responsible. Arjuna
Acetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, ChlorzoxazoneAcetazone Forte, Extra Strength Tylenol Aches & Strains, Parafon Forte
How Acetaminophen, Chlorzoxazone interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaChlorzoxazone (parafon Forte, Paraflex) Moderate
Interaction Summary
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Read the full Arjuna + Acetaminophen, Chlorzoxazone interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaChlorzoxazone (parafon Forte, Paraflex), Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Read the full Arjuna + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Arjuna + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Oxycodone interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna + Acetaminophen, Propoxyphene interactionAcetohexamideDymelor
How Acetohexamide interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Read the full Arjuna + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Arjuna + Acetylsalicylic Acid interactionAdagrasibKrazati
How Adagrasib interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna + Adagrasib interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Arjuna + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Arjuna + Agomelatine interactionAlbiglutideTanzeum
How Albiglutide interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Read the full Arjuna + Albiglutide interactionAlfentanilAlfenta
How Alfentanil interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna + Alfentanil interactionAlfuzosinUroxatral
How Alfuzosin interacts with Ajuna Chhal / Bark — through 1 ingredient. Tap an ingredient for the detail:
ArjunaCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna + Alfuzosin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Ajuna Chhal / Bark with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Arjuna
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.
Antidiabetes Drugs
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.
Chlorzoxazone (Parafon Forte, Paraflex)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.
Omeprazole (Prilosec)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.
Brand information
Manufacturer and brand details for Ajuna Chhal / Bark, from the product label.
Vedic Herbs
See all Vedic Herbs products- Name
- Sumitra Remedies LLC
- City
- New Brunswick
- State
- NJ
- ZipCode
- 08901
- Phone Number
- 1-612-888-3342
- Web Address
- www.vedicjuices.com
Ajuna Chhal / Bark by Vedic Herbs: Common Questions
Does Ajuna Chhal / Bark by Vedic Herbs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
Does Arjuna actually work for heart health or high cholesterol?
What are the side effects?
Does it matter which brand of Arjuna I buy?
What is Arjuna used for traditionally?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Ajuna Chhal / Bark is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Ajuna Chhal / Bark’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Ajuna Chhal / Bark's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 9 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Terminalia 9 references
- Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
- Rao, N. K. and Nammi, S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC.Complement Altern.Med 2006;6:17. PubMed
- Murali, Y. K., Anand, P., Tandon, V., Singh, R., Chandra, R., and Murthy, P. S. Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced
- Senthilkumar, G. P. and Subramanian, S. Evaluation of antioxidant potential of Terminalia chebula fruits studies in streptozotocin-induced diabetic rats. Pharmaceutical Biology (Netherlands) 2007;45:511-518.
- Malik N, Dhawan V, Bahl A, Kaul D. Inihbitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease. Platelets. 2009;20(3):183-1190.
- Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
- Wu G, Dong Z, Dong J, et al. Effects of mongolian medicine Terminalia chebula Retz. on 6 CYP450 enzymes in rats. Int J Clin Exp Pathol 2020;13(12):3128-3138.
- Das A, Naveen J, Sreerama YN, Gnanesh Kumar BS, Baskaran V. Low-glycemic foods with wheat, barley and herbs (Terminalia chebula, Terminalia bellerica and Emblica officinalis) inhibit a-amylase, a-glucosidase and DPP-IV activity in high fat and low dose st
- Eltimamy M, Elshamarka M, Aboelsaad M, Sayed M, Moawad H. Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats. J Diabetes Metab Disord 2022;21(1):159-170. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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