Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Angelica Root Ingredients & Drug Interactions

by Indiana Botanic Gardens

Angelica Root label
See full label image
Unknown Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Angelica Root against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Angelica Root is a dietary supplement by Indiana Botanic Gardens with 2 active ingredients. Its ingredients are commonly taken for general wellness and longevity, antioxidant support, heart and cholesterol health.Based on those ingredients, 186 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Angelica. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Angelica Root by Indiana Botanic Gardens

Ask about any prescription or over-the-counter medication and we check it for interactions with Angelica Root by Indiana Botanic Gardens — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Angelica Root by Indiana Botanic Gardens

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: angelica (also known as ashitaba). Angelica is a plant root traditionally used in herbal medicine.

The product has no other inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Ashitaba product and its label doesn't state a use — see Ashitaba's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold rates angelica for alcohol-related liver disease as insufficient — meaning there isn't enough reliable research to say whether it works for that purpose. If you're considering it for another reason, check with your pharmacist or doctor about what the science actually supports.

The evidence, ingredient by ingredient Ashitaba

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Angelica is likely safe when used as a food, but safety data for concentrated supplements hasn't been well studied, so we don't know much about side effects in people taking it this way. During pregnancy and breastfeeding, there isn't enough safety data — the facts recommend avoiding concentrated angelica supplements during both.

Side effects, ingredient by ingredient Ashitaba

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ashitaba.
  • The most serious interaction on file is rated Moderate.
  • For scale: 186 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check whether you take any medications broken down by the CYP1A2 enzyme (cytochrome P450 1A2) — a Moderate interaction is documented. Use the medication checker on this page to see your exact drugs.

If you're unsure, ask your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Angelica Root may be worth asking your pharmacist about if you're interested in herbal supplements and don't take CYP1A2 substrate medications. If you're pregnant, breastfeeding, or take any regular medications, check with us first.

We can help you decide if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Angelica Root, straight from the product label.

Brand Indiana Botanic Gardens
Barcode (UPC) 703308220032
Net contents 4 oz.
Market status On market
Date entered into DSLD Feb 25, 2013
DSLD ID 18262
Product type Botanical
Supplement form Unknown
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Angelica Root by Indiana Botanic Gardens, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s), 1 Teaspoon(s)
Maximum serving Sizes:
2 Gram(s), 1 Teaspoon(s)
Servings per container
75
UPC/BARCODE
703308220032
IngredientAmount% DV
Calories6 {Calories}--
Carbohydrates1 g1%
Angelica2 g--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: If you are using this product for any other purpose than as a spice, tea or seasoning please read the following warning: If you are taking any medications or are pregnant or nursing, do not use prior to consulting a physician.

KEEP OUT OF REACH OF CHILDREN

General Statements

Lot# 6064110

(Cut)

Seals/Symbols

IBG INDIANA BOTANIC GARDENS(R)

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Angelica Root by Indiana Botanic Gardens label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Angelica Root label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Angelica Root by Indiana Botanic Gardens

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Gram(s) Dosage formUnknown Servings per container75 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Carbohydrates

1 g per serving

Angelica

Interacts with
186 drugs
2 g per serving

Ashitaba is a leafy plant from Japan that is eaten as a vegetable and taken as a supplement for general health, antioxidant, and heart benefits. Most...

Angelica monograph & interactions
Interaction report

Angelica Root by Indiana Botanic Gardens Drug Interactions

Want to check YOUR meds against Angelica Root?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
186Drugs
186 Moderate

Ingredients driving the most interactions

Angelica 186

Individual Drug Interactions

The ingredients in Angelica Root interact with 186 drugs. Click any drug to see the details.

1 of the 2 ingredients in Angelica Root interact with drugs. Each result below shows which ingredient is responsible. Angelica

Each ingredient & the kinds of drugs it affects

For each ingredient in Angelica Root with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Angelica1 drug type · 186 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2. Theoretically, concomitant use of ashitaba with CYP1A2 substrates might decrease the clearance of these substrates and increase the risk for adverse effects. However, this interaction has yet to be reported in humans. Until more is known, use with caution.

Likelihood Possible Evidence D
Angelica full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Angelica Root, from the product label.

Indiana Botanic Gardens

See all Indiana Botanic Gardens products
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Angelica Root by Indiana Botanic Gardens: Common Questions

Does Angelica Root by Indiana Botanic Gardens interact with any medications?
Yes. Based on its ingredients, Angelica Root has a known interaction with 186 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Angelica Root contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is angelica safe during pregnancy?
There isn't enough safety data to know. The facts advise against concentrated angelica supplements while pregnant. Talk with your doctor or pharmacist about what's right for your situation.
Is angelica safe while breastfeeding?
There isn't enough safety data to know. The facts advise against concentrated angelica supplements while breastfeeding. Talk with your doctor or pharmacist before taking it.
What is angelica used for?
The evidence we hold rates angelica for alcohol-related liver disease as insufficient — meaning there's not enough reliable research to say whether it works. Your pharmacist can discuss other traditional uses and what the science actually supports.
Does angelica have any side effects?
Our data doesn't list specific side effects from people taking angelica supplements. Because supplement safety hasn't been well studied, we don't know what to expect. If you notice anything unusual after starting it, let your pharmacist know.
What's the difference between angelica as a food and as a concentrated supplement?
Angelica is likely safe when eaten as food, but safety data for concentrated supplements is sparse. This product is a concentrated supplement, so we know less about how it affects people taking it this way.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Angelica Root is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Angelica Root label
Go deeper

The Full Monographs Behind Angelica Root’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ashitaba

Interacts with 186 drugs

Ashitaba is a leafy plant from Japan that is eaten as a vegetable and taken as a supplement for general health, antioxidant, and heart benefits. Most of the supporting research comes from la...

Read the full Ashitaba monograph →
Sources

Sources & How We Checked

Angelica Root's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ashitaba 2 references
  1. Kwon D, Yoon S, Carter O, Bailey GS, Dashwood RH. Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. Biofactors. 2006;26(4):231
  2. Noh HM, Ahn EM, Yun JM, Cho BL, Paek YJ. Angelica keiskei Koidzumi extracts improve some markers of liver function in habitual alcohol drinkers: a randomized double-blind clinical trial. J Med Food. 2015;18(2):166-72.

See these in context on the Ashitaba monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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