Arginine-EE + TMG Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Arginine-EE + TMG against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Arginine-EE + TMG is a dietary supplement by Dr. Wong's Essentials with 3 active ingredients. Its ingredients are commonly taken for high homocysteine levels, liver health (fatty liver), exercise performance and strength.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Arginine-EE + TMG by Dr. Wong's Essentials
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains three active ingredients. Betaine anhydrous (also called anhydrous betain) is a compound that plays a role in cellular function and has been studied most thoroughly for a genetic condition called homocystinuria.
The other two actives — serratiopeptidase and arginine ethyl ester — round out the formula. You'll also find standard inactive ingredients like gelatin capsule material, vegetable cellulose, magnesium stearate, and silicon dioxide.
Does it work?
Strong evidence
The evidence picture is mixed. Betaine anhydrous is rated effective for homocystinuria and possibly effective for high homocysteine levels (hyperhomocysteinemia).
For other conditions in this formula — nonalcoholic fatty liver (NASH), colorectal adenoma, depression, and acid reflux — the evidence we have isn't strong enough to rate it either way. We hold no effectiveness data for serratiopeptidase or arginine ethyl ester in our records.
How safe is it?
Well-documented data
Betaine anhydrous is generally well tolerated at studied doses, but the safety data overall isn't extensive. The most common side effects are body odor, diarrhea, nausea, vomiting, GI upset, and elevated cholesterol levels.
A rare serious effect — cerebral edema (swelling in the brain) — has been reported, though it's uncommon. Safety during breastfeeding isn't well established, so caution is advised if you're nursing.
Check with your doctor or pharmacist before using this product.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. That said, we have no interaction data for serratiopeptidase or arginine ethyl ester, so if you take any medications, check them below to be sure.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.
This product is most straightforward if you're using it for homocystinuria under a doctor's supervision. If you're considering it for other reasons, the evidence is thin.
Anyone taking medications — especially blood thinners, heart drugs, or blood pressure meds — should run this past their pharmacist first. Pregnant or breastfeeding?
Talk to your doctor before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Arginine-EE + TMG, straight from the product label.
| Brand | Dr. Wong's Essentials |
|---|---|
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2019 |
| DSLD ID | 203921 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Arginine-EE + TMG by Dr. Wong's Essentials, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 1160 mg | -- |
| Serratiopeptidase | 0 NP | -- |
| Arginine Ethyl Ester Di-HCl | 0 NP | -- |
| Anhydrous Betain | 0 NP | -- |
Other ingredients: Gelatin, Vegetable Cellulose, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, 2 to 4 capsules daily as needed or as directed by your health care provider.
Precautions
Keep out of the reach of children.
Tamper resistant package. Do not use if outer seal is missing.
Formulation
This product contains no gluten, milk, eggs, wheat, soybeans, peanuts, tree nuts, fish or shellfish.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
New & improved formula
WAM Essentials, Inc. Fanning the winds of change
FDA Statement of Identity
A Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Arginine-EE + TMG by Dr. Wong's Essentials label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Arginine-EE + TMG by Dr. Wong's Essentials
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Serratiopeptidase
- › Arginine Ethyl Ester Di-HCl
- › Anhydrous Betain
Other (inactive) ingredients: Gelatin, Vegetable Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Arginine-EE + TMG by Dr. Wong's Essentials Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Arginine-EE + TMG. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Arginine-EE + TMG, from the product label.
Dr. Wong's Essentials
See all Dr. Wong's Essentials products- Name
- WAM Essentials, Inc.
- Street Address
- 320 Grant Ave.
- City
- Strawn
- State
- TX
- ZipCode
- 76475
- Phone Number
- 1-866-268-3216
Arginine-EE + TMG by Dr. Wong's Essentials: Common Questions
Does Arginine-EE + TMG by Dr. Wong's Essentials interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What's betaine anhydrous supposed to do in this formula?
Can I take this if I'm breastfeeding?
What side effects should I watch for?
Is this safe to use long-term?
Does this product have fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Arginine-EE + TMG is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Arginine-EE + TMG’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Arginine-EE + TMG's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 11 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Betaine Anhydrous 11 references
- Cystadane (betaine anhydrous for oral solution) Package insert. Orphan Medical, Inc. Minnetonka, MN. November 2005.
- Abdelmalek MF, Angulo P, Jorgensen RA, et al. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;96:2711-7.. PubMed
- Schwab U, Torronen A, Toppinen L, et al. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr 2002;76:961-7. PubMed
- McGregor DO, Dellow WJ, Robson RA, et al. Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure. Kidney Int 2002;61:1040-6. PubMed
- Olthof MR, van Vliet T, Verhoef P, et al. Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans. PloS Med 2005;2:e135. PubMed
- Knopman, D. and Patterson, M. An open-label, 24-week pilot study of the methyl donor betaine in Alzheimer disease patients. Alzheimer Dis.Assoc.Disord. 2001;15(3):162-165. PubMed
- Moat, S. J., Madhavan, A., Taylor, S. Y., Payne, N., Allen, R. H., Stabler, S. P., Goodfellow, J., McDowell, I. F., Lewis, M. J., and Lang, D. High- but not low-dose folic acid improves endothelial function in coronary artery disease. Eur J Clin Invest 2 PubMed
- Abdelmalek, M. F., Sanderson, S. O., Angulo, P., Soldevila-Pico, C., Liu, C., Peter, J., Keach, J., Cave, M., Chen, T., McClain, C. J., and Lindor, K. D. Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial. Hepa PubMed
- Ashtary-Larky D, Bagheri R, Ghanavati M, et al. Effects of betaine supplementation on cardiovascular markers: a systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2021 Mar 25:1-18. PubMed
- Zawieja EE, Zawieja B, Chmurzynska A. Betaine supplementation moderately increases total cholesterol levels: a systematic review and meta-analysis. J Diet Suppl. 2021;18(1):105-117. PubMed
- Imbard A, Toumazi A, Magréault S, et al. Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial. Orphanet J Rare Dis 2022;17(1):417. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC