Arjuna Ingredients & Drug Interactions
by Herbal Hills
What is this page for?
First and foremost: checking Arjuna against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Arjuna is a dietary supplement by Herbal Hills with 1 active ingredient. Its ingredients are commonly taken for heart health and circulation, digestive problems (constipation, diarrhea), cholesterol support.Based on those ingredients, 933 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Arjuna, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Arjuna by Herbal Hills
Ask about any prescription or over-the-counter medication and we check it for interactions with Arjuna by Herbal Hills — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Arjuna by Herbal Hills
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Arjuna by Herbal Hills contains one active ingredient: Arjuna powder (from Terminalia arjuna). There are no inactive ingredients listed for this product.
Does it work?
Not established
The evidence for Arjuna isn't established yet. Our data shows insufficient reliable evidence to rate it for obesity, high cholesterol, high blood pressure, or angina.
That doesn't mean it doesn't work — it means the studies so far haven't been strong enough to draw a firm conclusion. If you're thinking about taking it for one of these reasons, that's worth discussing with your pharmacist or doctor.
How safe is it?
Some data gaps
Arjuna is generally well tolerated in short-term studies, but long-term safety data and product quality vary. The safety information during pregnancy is not sufficient — the data advises against use during pregnancy.
The same goes for breastfeeding; there isn't enough information, and the data advises against use while breastfeeding.
Meds to double-check
Moderate interaction found
Before you take Arjuna, double-check any prescription medications you're on. The biggest concern is drugs broken down by your liver (CYP2D6, CYP2C9, or CYP3A4 substrates) — Arjuna can slow that process and raise drug levels.
Also check if you take blood thinners, diabetes medications, chlorzoxazone (a muscle relaxant), or omeprazole (heartburn medication).
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.
Arjuna might appeal to someone looking for a traditional approach to heart health or cholesterol, but the evidence isn't strong yet. If you take any prescription medications — especially blood thinners, diabetes drugs, or anything processed by the liver — you need to check with your pharmacist first.
Pregnant or breastfeeding? Skip it until you've talked to your doctor.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Arjuna, straight from the product label.
| Brand | Herbal Hills |
|---|---|
| Barcode (UPC) | 8904268846207 |
| Net contents | 16 Ounce(s); 454 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2025 |
| DSLD ID | 323822 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Halal |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Arjuna by Herbal Hills, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Arjuna, Powder | 3 Gram(s) | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Herbal Hills Back to Nature
Formula
Terminalia arjuna
QA ICS JAS-ANZ Halal India www.Halalindia.com HIW25610218
Suggested/Recommended/Usage/Directions
Directions for use: Take 3 gms powder, 1 to 2 times a day
Precautions
Warning: Pregnant or lactating women are advised to consume herbal products under the advice of the healthcare practitioner.
Keep out of reach of children.
Do not use if pouch is broken.
Storage
Storage: Store in a cool dry place away from direct sunlight.
Formulation
Being natural product. Colour may vary over time as well as from batch to batch however effectiveness remains same. Herbal Powder Pure Natural Effective Country of Origin: India
High quality natural products
General Statements
Neutral code: MH/AYU/25D-MH/102334
Seals/Symbols
QA ICS JAS-ANZ GMP Good Manufacturing Practice Halal India www.Halalindia.com HIW25610218
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Arjuna by Herbal Hills label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Arjuna by Herbal Hills
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Gram(s) Dosage formPowder Servings per container151 Amounts shown are per serving.
Arjuna, Powder
Interacts with933 drugs
Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes....
Arjuna, Powder monograph & interactionsArjuna by Herbal Hills Drug Interactions
HelloPharmacist Interaction Report
Arjuna by Herbal Hills is a single-ingredient powder that does interact with medications — and the interactions span a broad range.
The ingredient, Arjuna (Terminalia arjuna), inhibits three major liver enzymes (CYP2D6, CYP2C9, and CYP3A4) that break down many prescription drugs. When these enzymes are slowed, drug levels in your blood can build up, raising the risk of side effects.
Altogether, these interactions span 922 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Arjuna also carries Moderate interactions with blood thinners and antiplatelet drugs (like warfarin and clopidogrel), which increases bleeding risk when combined. It may also affect blood sugar control if you take diabetes medications, and can raise levels of two specific drugs: chlorzoxazone (a muscle relaxant) and omeprazole (a heartburn medication).
Because so many common medications are broken down by those three liver enzymes, you'll want to run your exact prescriptions through the interaction checker below before you start Arjuna.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Arjuna?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Arjuna interact with 933 drugs. Click any drug to see the details.
1 of the 1 ingredient in Arjuna interact with drugs. Each result below shows which ingredient is responsible. Arjuna, Powder
Acetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna, Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna, Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna, Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna, Powder + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, ChlorzoxazoneAcetazone Forte, Extra Strength Tylenol Aches & Strains, Parafon Forte
How Acetaminophen, Chlorzoxazone interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderChlorzoxazone (parafon Forte, Paraflex) Moderate
Interaction Summary
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Read the full Arjuna, Powder + Acetaminophen, Chlorzoxazone interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderChlorzoxazone (parafon Forte, Paraflex), Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Read the full Arjuna, Powder + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna, Powder + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna, Powder + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2c9 (cyp2c9) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Arjuna, Powder + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Oxycodone interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna, Powder + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Arjuna, Powder + Acetaminophen, Propoxyphene interactionAcetohexamideDymelor
How Acetohexamide interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Read the full Arjuna, Powder + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Arjuna, Powder + Acetylsalicylic Acid interactionAdagrasibKrazati
How Adagrasib interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna, Powder + Adagrasib interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Arjuna, Powder + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
Read the full Arjuna, Powder + Agomelatine interactionAlbiglutideTanzeum
How Albiglutide interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Read the full Arjuna, Powder + Albiglutide interactionAlfentanilAlfenta
How Alfentanil interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna, Powder + Alfentanil interactionAlfuzosinUroxatral
How Alfuzosin interacts with Arjuna — through 1 ingredient. Tap an ingredient for the detail:
Arjuna, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Arjuna, Powder + Alfuzosin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Arjuna with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Arjuna, Powder
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.
Antidiabetes Drugs
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.
Chlorzoxazone (Parafon Forte, Paraflex)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.
Omeprazole (Prilosec)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.
Brand information
Manufacturer and brand details for Arjuna, from the product label.
Herbal Hills
See all Herbal Hills products- Name
- Stelcore Management Services LLC (Importer)
- Street Address
- 8 Green Suite 5766
- City
- Dover
- State
- Delaware
- ZipCode
- 19901
- Web Address
- www.herbalhillsglobal.com
Arjuna by Herbal Hills: Common Questions
Does Arjuna by Herbal Hills interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is Arjuna safe to take while I'm pregnant or breastfeeding?
What's Arjuna actually used for?
Are there any side effects listed for Arjuna?
Why does this interact with so many medications?
Does this product have any fillers or other ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Arjuna is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Arjuna’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Arjuna's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 9 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Terminalia 9 references
- Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
- Rao, N. K. and Nammi, S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC.Complement Altern.Med 2006;6:17. PubMed
- Murali, Y. K., Anand, P., Tandon, V., Singh, R., Chandra, R., and Murthy, P. S. Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced
- Senthilkumar, G. P. and Subramanian, S. Evaluation of antioxidant potential of Terminalia chebula fruits studies in streptozotocin-induced diabetic rats. Pharmaceutical Biology (Netherlands) 2007;45:511-518.
- Malik N, Dhawan V, Bahl A, Kaul D. Inihbitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease. Platelets. 2009;20(3):183-1190.
- Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
- Wu G, Dong Z, Dong J, et al. Effects of mongolian medicine Terminalia chebula Retz. on 6 CYP450 enzymes in rats. Int J Clin Exp Pathol 2020;13(12):3128-3138.
- Das A, Naveen J, Sreerama YN, Gnanesh Kumar BS, Baskaran V. Low-glycemic foods with wheat, barley and herbs (Terminalia chebula, Terminalia bellerica and Emblica officinalis) inhibit a-amylase, a-glucosidase and DPP-IV activity in high fat and low dose st
- Eltimamy M, Elshamarka M, Aboelsaad M, Sayed M, Moawad H. Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats. J Diabetes Metab Disord 2022;21(1):159-170. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC