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Dietary supplement

Avocado Ingredients & Drug Interactions

by Hawaii Pharm

Avocado label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Avocado against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Avocado is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for heart and cholesterol health, osteoarthritis (as asu), general nutrition and healthy fats.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Avocado Seed Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Avocado by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Avocado by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Avocado by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Avocado Seed Extract, Dry. The extract is supplied as a liquid with alcohol, water, and glycerin as inactive ingredients (the carriers that hold the extract in solution).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Avocado's overall clinical evidence instead.

Moderate

Some clinical evidence supports Avocado for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Hypercholesterolemia — rated "Possibly Effective" (Natural Medicines).

The evidence supports avocado extract as possibly effective for lowering cholesterol (hypercholesterolemia). For metabolic syndrome, aging skin, and obesity, the evidence we hold is insufficient to rate whether it works.

That doesn't mean it doesn't; it means we don't have reliable data yet.

The evidence, ingredient by ingredient Avocado

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Avocado as a food is widely eaten and generally well tolerated. In clinical trials, the extract has been well tolerated when taken by mouth.

However, concentrated supplements or extracts haven't been well studied in pregnancy or breastfeeding, so the safety in those situations isn't clear. Rarely, avocado can trigger allergic reactions in people with latex allergies, or cause a severe food sensitivity reaction (FPIES) marked by vomiting and diarrhea within a few hours—this is most common in infants and young children.

Gastrointestinal upset has also been reported in some cases.

Side effects, ingredient by ingredient Avocado

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Avocado.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Warfarin (Coumadin) and other blood thinners are the main concern with this extract—it may reduce their effectiveness. Use the checker below to verify your specific medications before you start.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you take warfarin, check with your pharmacist before adding this product—the extract may reduce how well your blood thinner works. For cholesterol support, the evidence is there.

If you're pregnant, breastfeeding, or have a history of latex allergy or unusual food sensitivities, talk with your pharmacist about whether this extract is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Avocado, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253603432
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 301237
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Avocado by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253603432
IngredientAmount% DV
Avocado Seed Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Organic Alcohol Based USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get 15% discount on your next purchase. Limited time deal.

Formula

Persea americana

Organic Alcohol Based

Formulation

Only natural ingredients Purity is laboratory tested and verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Not tested on animals

Organic Alcohol Based

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Avocado by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Avocado label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Avocado by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Avocado Seed Extract, Dry

Interacts with
2 drugs
983 mg per serving Form: Persea americana Seed Extract, Dry

Avocado is a nutritious fruit rich in healthy monounsaturated fats, fiber, and potassium, and eating it as part of a balanced diet may support heart h...

Avocado Seed Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Avocado by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Avocado?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Moderate

Ingredients driving the most interactions

Avocado Seed Extract, Dry 2

Individual Drug Interactions

The ingredients in Avocado interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in Avocado interact with drugs. Each result below shows which ingredient is responsible. Avocado Seed Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Avocado with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Avocado Seed Extract, Dry1 drug type · 2 drugs

Warfarin (Coumadin)

Avocado may antagonize the anticoagulant effects of warfarin.
Avocado may antagonize the anticoagulant effects of warfarin; however, there has been only one case report of this interaction.

Likelihood Unlikely Evidence D
Avocado Seed Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Avocado, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Avocado by Hawaii Pharm: Common Questions

Does Avocado by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Avocado has a known interaction with 2 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Avocado contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this avocado extract interact with my warfarin?
Possibly. The extract may work against warfarin's blood-thinning effect. We only have one case report documented, but it's a real concern. Talk to your pharmacist or doctor before taking this if you're on warfarin—they may want to monitor you more closely.
Can I take this if I'm pregnant or breastfeeding?
The safety of concentrated avocado extract during pregnancy and breastfeeding isn't well established. While eating avocado as food is fine, this concentrated form hasn't been well studied in those situations. Talk with your doctor or pharmacist for personalized advice.
Does it work for high cholesterol?
The evidence suggests it's possibly effective for lowering cholesterol. For other uses like weight loss or metabolic syndrome, we don't have reliable data yet.
Is this safe if I have a latex allergy?
Be cautious. Avocado can trigger allergic cross-reactions in people with latex allergies, though this is rare. If you have a latex allergy, check with your pharmacist first.
What are the common side effects?
In clinical trials, avocado taken by mouth has been generally well tolerated. Gastrointestinal upset has been reported in some cases. Rarely, it can cause a severe food sensitivity reaction with vomiting and diarrhea, mostly in infants and young children.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Avocado is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Avocado label
Go deeper

The Full Monographs Behind Avocado’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Avocado

Interacts with 2 drugs

Avocado is a nutritious fruit rich in healthy monounsaturated fats, fiber, and potassium, and eating it as part of a balanced diet may support heart health. A specific extract called avocado...

Read the full Avocado monograph →
Sources

Sources & How We Checked

Avocado's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Avocado 10 references
  1. Blickstein D, Shaklai M, Inbal A. Warfarin antagonism by avocado. Lancet 1991;337:914-5. PubMed
  2. Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103(3 Pt 1):507-13. PubMed
  3. Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7. PubMed
  4. Stucker M, Memmel U, Hoffmann M, et al. Vitamin B(12) cream containing avocado oil in the therapy of plaque psoriasis. Dermatology 2001;203:141-7.
  5. Ahlroth, M., Alenius, H., Turjanmaa, K., Makinen-Kiljunen, S., Reunala, T., and Palosuo, T. Cross-reacting allergens in natural rubber latex and avocado. J.Allergy Clin.Immunol. 1995;96(2):167-173. PubMed
  6. de Groot, A. C., van der Meeren, H. L., and Weyland, J. W. Contact allergy to avocado oil in a sunscreen. Contact Dermatitis 1987;16(2):108-109. PubMed
  7. Blanco, C., Carrillo, T., Castillo, R., Quiralte, J., and Cuevas, M. Avocado hypersensitivity. Allergy 1994;49(6):454-459. PubMed
  8. Crisi, G. and Belsito, D. V. Contact urticaria from latex in a patient with immediate hypersensitivity to banana, avocado and peach. Contact Dermatitis 1993;28(4):247-248.
  9. Cherian S, Neupert K, Varshney P. Avocado as an emerging trigger for food protein-induced enterocolitis syndrome. Ann Allergy Asthma Immunol. 2018;121(3):369-71. PubMed
  10. Lichtenstein AH, Kris-Etherton PM, Petersen KS, et al. Effect of Incorporating 1 Avocado Per Day Versus Habitual Diet on Visceral Adiposity: A Randomized Trial. J Am Heart Assoc 2022;11(14):e025657.

See these in context on the Avocado monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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