No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Bayberry Ingredients & Drug Interactions

by Pure Herbs

Bayberry label
See full label image
Liquid Category: Botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bayberry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Bayberry is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for diarrhea and digestive upset, sore throat and cold symptoms, gum and mouth rinse (gargle).We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Bayberry by Pure Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bayberry root bark extract. Bayberry has been used traditionally in herbal medicine, though the scientific evidence for its benefits isn't established in the data we hold.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: healthy sinuses.
  • We looked for evidence on: Sinusitis, Nasal congestion, Sinus health.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The effectiveness of bayberry for any particular use isn't documented in our data. If you're considering this product for a specific health goal, talk with your pharmacist or doctor about what the evidence actually supports.

The evidence, ingredient by ingredient Bayberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Here's what matters: bayberry root bark carries real cautions. Large amounts can irritate your stomach and cause vomiting, possibly because of its tannin content — compounds in the plant that can be harsh on your digestive tract.

The bark also contains other compounds that raise safety concerns. Liver damage has been reported with oral use.

Additionally, bayberry isn't recommended during pregnancy or while breastfeeding — there simply isn't enough safety information to know it's okay. If you have a sensitive stomach, liver problems, or you're pregnant or nursing, this isn't the right choice for you.

Even if none of those apply, talk with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Bayberry

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for bayberry. That doesn't mean none exist — this ingredient simply hasn't been extensively studied with medications.

Check your exact prescriptions with your doctor or pharmacist before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Bayberry root bark extract has been used traditionally, but the scientific evidence for what it does is thin, and the safety data raises real concerns — especially for your stomach and liver. If you're pregnant, nursing, or have digestive or liver issues, skip it.

For anyone else thinking about it, have a conversation with your own doctor or pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bayberry, straight from the product label.

Brand Pure Herbs
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 278738
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bayberry by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
15
IngredientAmount% DV
Bayberry Root Bark Extract1986 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.

Shake well before use

Formulation

Beneficial for healthy sinuses.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.

Discontinue use and consult with your doctor if any adverse reactions occur.

Keep out of reach of children

Brand IP Statement(s)

Pure Herbs, Ltd. Natural Herbal Extracts

FDA Statement of Identity

Dietary Supplement

General Statements

"No expense has been spared to provide the finest nature has to offer."

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bayberry by Pure Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bayberry label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bayberry by Pure Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.

Bayberry Root Bark Extract

No known
interactions
1986 mg per serving

Bayberry is a traditional herb used mainly as an astringent for diarrhea, sore throats, and minor skin or gum problems, but there is very little moder...

Bayberry Root Bark Extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bayberry by Pure Herbs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Bayberry. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Bayberry, from the product label.

Pure Herbs

See all Pure Herbs products
Name
Pure Herbs, Ltd.
City
Sterling Heights
State
MI
Phone Number
(800) 860-4372
Web Address
www.pureherbs.com
Pharmacist Counseling Corner

Bayberry by Pure Herbs: Common Questions

Does Bayberry by Pure Herbs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Bayberry. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Bayberry contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take bayberry if I'm pregnant or breastfeeding?
No. The safety data rates bayberry as possibly unsafe during pregnancy and while breastfeeding. There isn't enough information to know it's okay, so it's best avoided in both situations.
What are the side effects of bayberry?
Bayberry can cause stomach irritation, vomiting, and liver damage — possibly from its tannin content, which is harsh on the digestive tract. It can also act as an irritant and sensitizer to your skin or tissues. Large amounts are more likely to cause problems.
Is bayberry safe if I have a sensitive stomach?
No. Because bayberry can irritate your stomach and cause vomiting, it's not a good choice if your digestive system is already sensitive. Talk with your doctor or pharmacist about whether it's right for you.
Does bayberry interact with any medications?
No interactions are documented in our data for this ingredient. That said, bayberry hasn't been extensively studied with drugs, so absence of documented interactions isn't a guarantee none exist. Run your prescriptions through our search tool and check with your pharmacist.
What is bayberry used for?
Bayberry has been used in traditional herbal medicine, but the scientific evidence for what it actually does isn't established in our data. If you're taking it for a specific reason, ask your pharmacist or doctor whether the evidence supports that use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bayberry is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bayberry label
Go deeper

The Full Monographs Behind Bayberry’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bayberry

Bayberry is a traditional herb used mainly as an astringent for diarrhea, sore throats, and minor skin or gum problems, but there is very little modern human research to confirm it works. It...

Read the full Bayberry monograph →
Sources

Sources & How We Checked

Bayberry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bayberry 3 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

See these in context on the Bayberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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