No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Be-Flexible Ingredients & Drug Interactions

by GNC WellBeing

Other (e.g. Tea Bag) Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Be-Flexible is a dietary supplement by GNC WellBeing with 3 active ingredients. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Be-Flexible by GNC WellBeing

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Be-Flexible is a three-ingredient product. One active ingredient we can identify is Hyaluronic Acid, a naturally occurring compound used in eye care and for skin health.

The product also contains MSM and a proprietary blend, though we don't have detailed breakdowns of what those contribute. The remaining ingredients — cellulose, mica, titanium dioxide, mint flavoring, and a few others — are inactive ingredients used to form and flavor the product.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Hyaluronic Acid's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Mobility and stretch flexibility.
  • We looked for evidence on: Osteoarthritis, Exercise-induced muscle soreness, Wound healing, Joint flexibility, Connective tissue support, Range of motion.
  • The closest evidence on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis, Wound healing.

Hyaluronic Acid in this product has shown promise for dry eye (possibly effective) and venous leg ulcers — wounds on the lower leg related to poor circulation (possibly effective). For aging skin, hay fever, and sexual dysfunction, the evidence is currently insufficient to rate whether it works.

We have no effectiveness data on file for MSM or the proprietary blend.

The evidence, ingredient by ingredient Hyaluronic Acid

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hyaluronic Acid is generally well tolerated when taken by mouth or applied to skin. The safety notes we hold, however, advise caution: long-term safety of supplements isn't fully studied, and there isn't enough safety data for oral supplements unless your doctor recommends otherwise.

Topical use (on skin) has occasionally caused eczema, redness, itching, or minor wound issues. Eye drops with hyaluronic acid have rarely caused eye pain.

We have no pregnancy or breastfeeding safety information on file for any of the ingredients in this product.

Side effects, ingredient by ingredient Hyaluronic Acid

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient we could check. Still, we hold no interaction data for MSM or the proprietary blend, so check your exact medications using the search tool on this page to be sure.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Be-Flexible may be worth trying if you're looking for support with dry eye or skin health, though the evidence is modest. Because long-term safety of this supplement isn't fully studied and we have limited safety data for oral use, talk with your pharmacist or doctor before starting — especially if you're pregnant, nursing, or taking other medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Be-Flexible, straight from the product label.

Brand GNC WellBeing
Market status On market
Date entered into DSLD Feb 23, 2012
DSLD ID 5730
Product type Other Combinations
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Be-Flexible by GNC WellBeing, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
1 Caplet(s)
IngredientAmount% DV
MSM250 mg--
Fast-Acting Proprietary Blend250 mg--
Hyaluronic Acid5 mg--

Other ingredients: Cellulose, Mica, Titanium Dioxide, natural Mint flavor, Vegetable Acetoglycerides, Sucralose, Chlorophyll

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

GNC QUALITY COMMITMENT GNC, the leader in the development and manufacture of dietary supplements, is committed to producing the highest quality products available. This commitment begins with quality designed supplement formulations. Every raw material that goes into a GNC supplement is guaranteed as to quality and potency. Each product is dated and then shipped immediately to our stores, so you can be sure you are purchasing the freshest supplements available. At GNC, we extend our quality commitment to you by offering our money-back guarantee.

Now with the help of be-WHOLESOME, it's simple for you to achieve your daily nutritional goals. Carry your daily pak in your purse, gym bag or pocket!

GNC GUARANTEE Use any GNC supplement for as little as 10 days. If you are not 100% completely satisfied, return the unused portion of the product with proof of purchase to your GNC store for a complete refund of your purchase price. No questions asked!

be-WHOLE, be-BEAUTIFUL, be-FLEXIBLE, be-PROTECTED, be-BALANCED…be-WHOLESOME!

be-WHOLE be-BEAUTIFUL be-FLEXIBLE be-PROTECTED be-BALANCED

Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

Precautions

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.

KEEP OUT OF REACH OF CHILDREN.

Brand IP Statement(s)

Daily Pak includes: be-WHOLE(TM) - Multivitamin & mineral be-BEAUTIFUL(TM)- Hair, skin & nail formula be-FLEXIBLE(TM)- Mobility & stretch formula be-PROTECTED(TM)- Triple strength fish oil be-BALANCED(TM)- Bone strengthening formula

HEALTH & BEAUTY VITAPAK(R)

be-WHOLESOME(TM) HEALTH & BEAUTY VITAPAK(R) Not sure which vitamins to take? Think no more… We all want a life that's simple, complete and fulfilling. Now, GNC has a nutritional program that's just that. be-WHOLESOME conveniently provides you with the nutrients needed to keep you looking and feeling great - from complete multivitamin support to bone health, beauty nutrients and more - be-WHOLESOME has got it.

be-FLEXIBLE(TM)

be-FLEXIBLE(TM) mobility & stretch formula: when you're working out, support for stiff joints is a must. This fast-acting mobility formula features a clinically-studied blend of herbs shown to support joint flexibility and mobility and promote the body's natural ability to maintain joint structure and function.*

General

CODE 669411 IKG

Formula

Suitable for individuals following a low lactose diet.

dietary supplement for women

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take the contents of one pak daily with food.

Formulation

No Artificial Colors, No Artificial Flavors, No Wheat, No Gluten, Yeast Free.

See for yourself

Be-Flexible by GNC WellBeing label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Be-Flexible by GNC WellBeing

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

MSM

250 mg per serving

Fast-Acting Proprietary Blend

250 mg per serving Form: Chinese Skullcap root extract, Cutch Tree wood & bark extract

Hyaluronic Acid

No known
interactions
5 mg per serving Form: Sodium Hyaluronate

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin...

Hyaluronic Acid monograph & interactions

Other (inactive) ingredients: Cellulose, Mica, Titanium Dioxide, Natural Mint flavor, Vegetable Acetoglycerides, Sucralose, Chlorophyll. These complete the product’s ingredient list but are not active constituents.

Interaction report

Be-Flexible by GNC WellBeing Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Be-Flexible. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Be-Flexible, from the product label.

GNC WellBeing

See all GNC WellBeing products
Phone Number
1-888-462-2548
Pharmacist Counseling Corner

Be-Flexible by GNC WellBeing: Common Questions

Does Be-Flexible by GNC WellBeing interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Be-Flexible. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Be-Flexible contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Hyaluronic Acid and what's it supposed to do?
Hyaluronic Acid is a compound your body makes naturally. In this product, it's used to support dry eye and skin health. It's shown promise for dry eye and leg wound healing, though the evidence for aging skin and other uses is still being studied.
Is this safe to take long-term?
Hyaluronic Acid is generally well tolerated, but long-term safety of supplements overall isn't fully researched. The data we hold advises caution and recommends talking with your doctor before using oral supplements unless they've cleared it.
Can I use this while pregnant or breastfeeding?
We don't have safety information on file for any ingredient in this product during pregnancy or breastfeeding. Talk with your doctor or pharmacist before taking it if you're pregnant, nursing, or planning to become pregnant.
What are the side effects?
Hyaluronic Acid is generally well tolerated by mouth and on skin. When applied topically, it's rarely caused itching, redness, eczema, or minor wound issues. Eye drops have rarely caused eye pain. We have no adverse effect data for MSM or the proprietary blend.
Will this help with joint flexibility?
We have no effectiveness data on file for how this product supports joint flexibility — that's not covered in the product facts we hold.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Be-Flexible is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Be-Flexible label
Go deeper

The Full Monographs Behind Be-Flexible’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Be-Flexible's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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