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Dietary supplement

Bee-P-Plus Ingredients & Drug Interactions

by Douglas Laboratories

Bee-P-Plus label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bee-P-Plus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bee-P-Plus is a dietary supplement by Douglas Laboratories with 1 active ingredient. Its ingredients are commonly taken for general energy and vitality, immune support, nutritional supplement.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pure Bee Pollen. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bee-P-Plus by Douglas Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Bee-P-Plus by Douglas Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bee-P-Plus by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Bee-P-Plus is a single-ingredient supplement containing pure bee pollen — the pollen and nectar collected by honeybees. The tablet also includes inactive ingredients: cellulose, calcium phosphate, fructose, vegetable stearate, and silica, which are binders and fillers that hold the tablet together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Bee Pollen product and its label doesn't state a use — see Bee Pollen's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for bee pollen's effectiveness is limited. For athletic performance, the data suggests it's probably not effective.

For allergic rhinitis (hay fever), benign prostatic hyperplasia, and breast cancer-related hot flashes, there isn't enough reliable evidence to say whether it works or doesn't. We simply don't have strong clinical trial data to support these uses.

The evidence, ingredient by ingredient Bee Pollen

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bee pollen is generally well tolerated by most people, but allergic reactions — sometimes serious — are a real concern. If you have a history of seasonal pollen allergies, especially to ragweed, chrysanthemums, marigolds, daisies, or related plants, you're at higher risk for severe reactions including swelling, shortness of breath, and in rare cases anaphylaxis.

Rare serious side effects reported include acute liver inflammation, kidney problems, and kidney failure. Bee pollen is rated possibly unsafe in pregnancy because of concern it may stimulate the uterus, so it should be avoided if you're pregnant.

There isn't enough safety data for breastfeeding, so it's best avoided while nursing as well.

Side effects, ingredient by ingredient Bee Pollen

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bee Pollen.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Bee-P-Plus, check with your pharmacist if you're on warfarin or any other blood thinner — bee pollen is documented to interact with these medications and increase bleeding risk. Altogether, these interactions span 2 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Bee-P-Plus may be worth considering if you're looking for a bee pollen supplement and have no history of pollen allergies. If you take warfarin or any blood thinner, you need to talk with your pharmacist or doctor first — this product can affect how those drugs work.

Anyone with seasonal allergies to ragweed or related plants should also check with us before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bee-P-Plus, straight from the product label.

Brand Douglas Laboratories
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Jun 25, 2012
DSLD ID 9409
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bee-P-Plus by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
IngredientAmount% DV
Pure Bee Pollen500 mg--

Other ingredients: Cellulose, Calcium Phosphate, Fructose, Vegetable Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Formulation

This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, starch, artificial coloring, preservatives or flavoring.

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 1 or more tablets daily or as directed by physician.

Precautions

KEEP OUT OF REACH OF CHILDREN.

TAMPER RESISTANT PACKAGE, DO NOT USE IF OUTER SEAL IS MISSING.

Storage

STORE IN A COOL, DRY PLACE.

General

Formula #7995

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bee-P-Plus by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bee-P-Plus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bee-P-Plus by Douglas Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Pure Bee Pollen

Interacts with
2 drugs
500 mg per serving

Bee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most...

Pure Bee Pollen monograph & interactions

Other (inactive) ingredients: Cellulose, Calcium Phosphate, Fructose, Vegetable Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bee-P-Plus by Douglas Laboratories Drug Interactions

Want to check YOUR meds against Bee-P-Plus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Moderate

Ingredients driving the most interactions

Pure Bee Pollen 2

Individual Drug Interactions

The ingredients in Bee-P-Plus interact with 2 drugs. Click any drug to see the details.

1 of the 1 ingredient in Bee-P-Plus interact with drugs. Each result below shows which ingredient is responsible. Pure Bee Pollen

Each ingredient & the kinds of drugs it affects

For each ingredient in Bee-P-Plus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pure Bee Pollen1 drug type · 2 drugs

Warfarin (Coumadin)

There is some concern that bee pollen might interact with warfarin and increase the risk of bleeding.
In one case report, a patient on warfarin had a stable international normalized ratio (INR) of 1.9-3.3 for 9 months. The patient's INR was found to be 7.1 after starting bee pollen granules one teaspoon twice daily for approximately one month. The patient's warfarin dose was decreased by approximately 11% in order to return the INR to the therapeutic range while continuing the bee pollen supplement.

Likelihood Possible Evidence D
Pure Bee Pollen full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bee-P-Plus, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
City
Pittsburgh
State
PA
ZipCode
15205
Pharmacist Counseling Corner

Bee-P-Plus by Douglas Laboratories: Common Questions

Does Bee-P-Plus by Douglas Laboratories interact with any medications?
Yes. Based on its ingredients, Bee-P-Plus has a known interaction with 2 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bee-P-Plus contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have allergies to pollen or ragweed?
No — if you have a history of seasonal pollen allergies, especially to ragweed, chrysanthemums, marigolds, or daisies, bee pollen can trigger serious allergic reactions including swelling, shortness of breath, and in rare cases anaphylaxis. Talk to your pharmacist or doctor first.
Is bee pollen safe to take while pregnant?
The safety data rates bee pollen as possibly unsafe in pregnancy because of concern it may stimulate the uterus. It's best to avoid it if you're pregnant. Talk with your doctor or pharmacist for personalized advice.
Can I take this while breastfeeding?
There isn't enough safety data to know either way. To be cautious, it's best avoided while breastfeeding. Talk with your doctor or pharmacist about whether it's right for you.
Does bee pollen really improve athletic performance?
The evidence suggests it probably doesn't improve athletic performance. Clinical trials haven't supported this use, so there are better-studied options if that's your goal.
What are the main side effects I should watch for?
Most people tolerate bee pollen well, but allergic reactions are the main concern — itching, swelling, shortness of breath, and lightheadedness. Rare serious effects include liver inflammation and kidney problems. Stop and seek medical help if you develop any of these symptoms.
Does this contain any fillers or other ingredients besides bee pollen?
Yes — the tablet includes cellulose, calcium phosphate, fructose, vegetable stearate, and silica as inactive binders and fillers to hold it together. The active ingredient is the bee pollen itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bee-P-Plus is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bee-P-Plus label
Go deeper

The Full Monographs Behind Bee-P-Plus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bee Pollen

Interacts with 2 drugs

Bee pollen is a nutrient-rich product collected by bees and marketed as a 'superfood' for energy and immune support, but solid human evidence for most of these claims is lacking. It can caus...

Read the full Bee Pollen monograph →
Sources

Sources & How We Checked

Bee-P-Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bee Pollen 15 references
  1. Foster S, Tyler VE. Tyler's Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd ed., Binghamton, NY: Haworth Herbal Press, 1993.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  4. Shad JA, Chinn CG, Brann OS. Acute hepatitis after ingestion of herbs. South Med J 1999;92:1095-7. PubMed
  5. Puente S, Iniguez A, Subirats M, et al. [Eosinophilic gastroenteritis caused by bee pollen sensitization]. Med Clin (Barc) 1997;108:698-700.
  6. Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
  7. Cohen SH, Yunginger JW, Rosenberg N, Fink JN. Acute allergic reaction after composite pollen ingestion. J Allergy Clin Immunol 1979;64:270-4. PubMed
  8. Hurren KM, Lewis CL. Probable interaction between warfarin and bee pollen. Am J Health Syst Pharm 2010;67:2034-7. PubMed
  9. Akiyasu T, Paudyal B, Paudyal P, et al. A case report of acute renal failure associated with bee pollen contained in nutritional supplements. Ther Apher Dial 2010;14:93-7. PubMed
  10. Greenberger, P. A. and Flais, M. J. Bee pollen-induced anaphylactic reaction in an unknowingly sensitized subject. Ann.Allergy Asthma Immunol 2001;86(2):239-242. PubMed
  11. Lin FL, Vaughan TR, Vandewalker ML, et al. Hypereosinophilia, neurologic, and gastrointestinal symptoms after bee-pollen ingestion. J Allergy Clin Immunol 1989;83(4):793-796. PubMed
  12. Mansfield LE, Goldstein GB. Anaphylactic reaction after ingestion of local bee pollen. Ann Allergy 1981;47(3):154-156.
  13. Choi JH, Jang YS, Oh JW, Kim CH, Hyun IG. Bee pollen-induced anaphylaxis: a case report and literature review. Allergy Asthma Immunol Res 2015 Sep;7(5):513-7. PubMed
  14. Nonotte-Varly C. Allergenicity of Artemisia contained in bee pollen is proportional to its mass. Eur Ann Allergy Clin Immunol 2015;47(6):218-24.
  15. Leang ZX, Thalayasingam M, O'Sullivan M. A paediatric case of exercise-augmented anaphylaxis following bee pollen ingestion in Western Australia. Asia Pac Allergy. 2022 Jul 12;12(3):e23. PubMed

See these in context on the Bee Pollen monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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