Benfotiamine 150 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Benfotiamine 150 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Benfotiamine 150 mg is a dietary supplement by Doctor's Best with 2 active ingredients. Its ingredients are commonly taken for diabetic nerve pain (neuropathy), supporting healthy nerve function, thiamine deficiency.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Benfotiamine 150 mg by Doctor's Best
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains two active ingredients: benfotiamine (a fat-soluble form of thiamine, or vitamin B1) and L-leucine (an amino acid your body uses to build and repair muscle). The capsule itself is made from modified cellulose, microcrystalline cellulose, and silicon dioxide — standard inactive ingredients that help form and stabilize the capsule.
Does it work?
Moderate evidence
Benfotiamine is possibly effective for diabetic nerve pain (neuropathy). For other conditions in our data — diabetic kidney damage, alcohol use disorder, Alzheimer disease, and general nerve pain — either the evidence is insufficient to rate it or it's rated possibly ineffective.
We hold no effectiveness data for L-leucine in this product's context.
How safe is it?
Well-documented data
Benfotiamine is generally well tolerated in the studies we reviewed, though long-term safety isn't fully established. In a six-week trial at higher doses (300–600 mg daily), a small number of participants reported allergic skin reactions or mild stomach discomfort, but these rates were no higher than placebo.
There isn't enough safety information to know whether benfotiamine is safe during pregnancy, so talk with your doctor or pharmacist before using it if you're pregnant. Safety while breastfeeding hasn't been well studied either, so caution is advised if you're nursing.
Meds to double-check
No known interactions
No interactions are documented in our data for the benfotiamine in this product. We could not check L-leucine, so mention all ingredients to your pharmacist if you're on any medications.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
If you have diabetic nerve pain, benfotiamine may be worth discussing with your doctor — the evidence supports a possible benefit. For other uses, the science is less clear.
This product appears to interact with no medications we've checked, but talk with your doctor or pharmacist before starting it, especially if you're pregnant, breastfeeding, or taking other supplements.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Benfotiamine 150 mg, straight from the product label.
| Brand | Doctor's Best |
|---|---|
| Barcode (UPC) | 753950001299 |
| Net contents | 120 Veggie Cap(s) |
| Market status | On market |
| Date entered into DSLD | Jul 21, 2022 |
| DSLD ID | 269347 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Benfotiamine 150 mg by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Leucine | 12 mg | -- |
| Benfotiamine | 150 mg | -- |
Other ingredients: Modified Cellulose, Microcrystalline Cellulose, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Benfotiamine (S-benzoylthiamine-O-monophosphate) is a derivative of thiamin, belonging to the family of compounds known as "allthiamines." Benfotiamine is fat-soluble and more bioavailable and physiologically active than thiamin. Benfotiamine raises the blood level of thiamin pyrophosphate (TPP), the biologically active co-enzyme of thiamin, and stimulates transketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways.
With BENFOPURE
Formulation
Helps maintain healthy cells in the presence of blood glucose Helps control formation of advanced Glycation End products (AGEs) Helps normalize cellular processes fueled by glucose metabolites
Helps maintain healthy glucose metabolism
Vegan
Non-GMO Gluten free Soy free
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
The BenfoPure logo design is a trademark of Hamari Chemicals Ltd., Japan. Science-Based Nutrition
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Adult Use: Take 1 capsule daily, with or without food, or as recommended by a nutritionally-informed physician.
Storage
Store in a cool dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Benfotiamine 150 mg by Doctor's Best label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Benfotiamine 150 mg by Doctor's Best
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Leucine
Benfotiamine
No knowninteractions
Benfotiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) that the body may absorb more easily than regular thiamine. It is mostly studied...
Benfotiamine monograph & interactionsOther (inactive) ingredients: Modified Cellulose, Microcrystalline Cellulose, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Benfotiamine 150 mg by Doctor's Best Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Benfotiamine 150 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Benfotiamine 150 mg, from the product label.
Doctor's Best
See all Doctor's Best products- Name
- Doctor's Best, Inc.
- State
- California
- Phone Number
- (800) 777-2474
- Web Address
- www.drbvitamins.com
Benfotiamine 150 mg by Doctor's Best: Common Questions
Does Benfotiamine 150 mg by Doctor's Best interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does benfotiamine do?
Are there any side effects?
Is this safe during pregnancy?
Is this safe while breastfeeding?
What is L-leucine in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Benfotiamine 150 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Benfotiamine 150 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Benfotiamine 150 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 1 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Benfotiamine 1 reference
- Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes 2008;116(10):600-5. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC