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Dietary supplement

BergaCor Plus Ingredients & Drug Interactions

by XYMOGEN

Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

BergaCor Plus is a dietary supplement by XYMOGEN with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, cholesterol and heart health, immune support.Based on those ingredients, 509 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bergamot extract, Amla Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of BergaCor Plus by XYMOGEN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

BergaCor Plus contains two active ingredients. Amla extract comes from Indian gooseberries and is included for its possible effects on reflux (GERD) and cholesterol levels.

Bergamot extract is the second active ingredient, used for its possibly effective role in managing high cholesterol (hyperlipidemia). The product also includes inactive ingredients—fillers and binders like microcrystalline cellulose, croscarmellose sodium, and medium chain triglyceride—to form the tablet.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: cardiovascular wellness and antioxidant support.
  • We looked for evidence on: Cardiovascular disease (CVD), Dyslipidemia, Hypercholesterolemia, Hyperlipidemia, Hypertension, Metabolic syndrome — and 3 related terms.
  • The strongest evidence on file: Bergamot is rated "Possibly Effective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Indian Gooseberry is rated "Possibly Effective" for Dyslipidemia.
  • Also on file: Bergamot is rated "Insufficient Reliable Evidence To Rate" for Metabolic syndrome.

For GERD reflux symptoms, amla extract is rated possibly effective based on the evidence we have. For cholesterol and high lipid levels, bergamot extract is also rated possibly effective.

Amla extract is possibly effective for high cholesterol as well. Beyond those uses, the evidence we hold is insufficient to rate amla for hair loss or bergamot for fatty liver disease, autism spectrum disorder, or mental alertness—though bergamot is rated possibly ineffective for mental alertness.

The evidence, ingredient by ingredient Indian Gooseberry Bergamot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Amla extract is generally well tolerated as a food, but supplement safety at higher doses is less well studied. The safety data advises against use during breastfeeding due to too little reliable information.

For bergamot extract, the oral form appears generally well tolerated short-term, but the essential oil can be toxic if swallowed. The safety data advises against bergamot supplements during pregnancy and breastfeeding because there isn't enough safety information.

In clinical trials, amla has been associated with upset stomach or indigestion in a small number of participants, and one person reported fatigue and three reported muscle or joint pain. Bergamot extract was linked to one case of heartburn.

Topical bergamot can cause blisters, redness, skin lesions, and photosensitivity, especially in fair-skinned people—frequent contact with the peel or oil is a particular concern.

Side effects, ingredient by ingredient Indian Gooseberry Bergamot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Bergamot, Indian Gooseberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 509 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking BergaCor Plus, double-check with your doctor or pharmacist if you take blood thinners (anticoagulants) or antiplatelet drugs like clopidogrel (Plavix), aspirin, diabetes medications, or photosensitizing drugs. These are the medication types with documented Moderate-severity interactions with the ingredients in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

BergaCor Plus may help with reflux and cholesterol if that's what you're after, but it's not right for everyone. If you take blood thinners, aspirin, diabetes medications, or drugs that increase sun sensitivity, you'll want to check with your doctor or pharmacist before starting it.

The same goes if you're pregnant or breastfeeding—talk it over with your own healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BergaCor Plus, straight from the product label.

Brand XYMOGEN
Barcode (UPC) 871149007294
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 303648
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BergaCor Plus by XYMOGEN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
30
UPC/BARCODE
871149007294
IngredientAmount% DV
Amla Extract500 mg--
Bergamot extract800 mg--

Other ingredients: Croscarmellose Sodium, Microcrystalline Cellulose, Ascorbyl Palmitate, Silica, Hydroxypropyl Methylcellulose, Medium Chain Triglyceride

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take one to two tablets twice daily, or as directed by your healthcare professional.

Precautions

Consult your healthcare practitioner prior to use.

Individuals taking medication should discuss potential interactions with their healthcare practitioner.

Do not use if tamper seal is damaged.

Formula

BergaCor Plus combines the antioxidant activity of bergamot (Citrus bergamia) with the tonifying superfruit of amla (Phyllanthus emblica). Bergamot is used traditionally in Italy to support cardiovascular wellness. Amla is revered in Ayurveda for its role in cardiovascular health, and this use has been validated in modern human clinical trials. Research suggests that the lipid- and glucose-balancing flavonoids of bergamot and amla help maintain healthy cholesterol levels already within normal range and support healthy blood glucose metabolism.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Storage: Keep closed in a cool, dry place out of reach of children.

Formulation

Formulated to exclude: Wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, sesame, ingredients derived from genetically modified organisms (GMOs), artificial colors, and artificial sweeteners.

Cardiovascular and Blood Sugar support from Bergamot and Amla

Brand IP Statement(s)

Copyright 2023 Xymogen

XYMOGEN Exclusive Professional Formulas

S1. Bergamot Polyphenolic Fraction Gold (BPFG) is a registered trademark of H&AD S.R.L. S2. Capros is a registered trademark of Natreon Inc.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

ePV (ePedigree Verification)

Third-Party Verified GMP Compliant

General Statements

Scan to Learn More! This package is completely recyclable

See for yourself

BergaCor Plus by XYMOGEN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in BergaCor Plus by XYMOGEN

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Amla Extract

Interacts with
208 drugs
500 mg per serving Form: Emblica officinalis Fruit Extract, Tannins

Indian gooseberry (amla) is a vitamin C-rich fruit used in Ayurvedic medicine for many purposes, from antioxidant support to cholesterol and digestion...

Amla Extract monograph & interactions

Bergamot extract

Interacts with
410 drugs
800 mg per serving Form: Brutieridine, Melitidine, Naringin, Neoeriocitrin, Neohesperidin, Total Polyphenols

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but...

Bergamot extract monograph & interactions

Other (inactive) ingredients: Croscarmellose Sodium, Microcrystalline Cellulose, Ascorbyl Palmitate, Silica, Hydroxypropyl Methylcellulose, Medium Chain Triglyceride. These complete the product’s ingredient list but are not active constituents.

Interaction report

BergaCor Plus by XYMOGEN Drug Interactions

Want to check YOUR meds against BergaCor Plus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
509Drugs
509 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in BergaCor Plus with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bergamot extract2 drug types · 410 drugs

Antidiabetes Drugs

Theoretically, taking bergamot with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that bergamot juice has hypoglycemic effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.
Bergamot contains bergapten, which has photosensitizing effects.

Likelihood Probable Evidence D

Amla Extract4 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, Indian gooseberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking Indian gooseberry 500 mg along with clopidogrel 75 mg or ecosprin 75 mg, as a single dose or for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg or ecosprin 75 mg alone. Until more is known, use caution when taking Indian gooseberry in combination with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Taking Indian gooseberry with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking Indian gooseberry fruit or fruit extract alone or in conjunction with antidiabetes medications can lower blood glucose levels. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Aspirin

Theoretically, Indian gooseberry may increase the risk of bleeding if used with aspirin; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with ecosprin 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus ecosprin 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with ecosprin 75 mg alone.

Likelihood Possible Evidence B
Clopidogrel (Plavix)

Theoretically, Indian gooseberry may increase the risk of bleeding if used with clopidogrel; however, research is conflicting.
Clinical research shows that taking Indian gooseberry 500 mg as a single dose or twice daily for 10 days reduces platelet aggregation by about 24% to 36%, increases bleeding time by about 3.8-5.9 seconds, and increases clotting time by about 9.8-12.7 seconds when compared to baseline. However, taking a single dose of Indian gooseberry 500 mg along with clopidogrel 75 mg, or taking a combination of Indian gooseberry 500 mg twice daily plus clopidogrel 75 mg once daily for 10 days, does not significantly reduce platelet aggregation or increase bleeding time or clotting time when compared with clopidogrel 75 mg alone.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for BergaCor Plus, from the product label.

XYMOGEN

See all XYMOGEN products
Name
XYMOGEN
Street Address
6900 Kingspointe Pkwy.
City
Orlando
State
FL
ZipCode
32819
Phone Number
800-647-6100
Web Address
www.xymogen.com
Pharmacist Counseling Corner

BergaCor Plus by XYMOGEN: Common Questions

Does BergaCor Plus by XYMOGEN interact with any medications?
Yes. Based on its ingredients, BergaCor Plus has a known interaction with 509 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BergaCor Plus contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is amla extract, and why is it in this product?
Amla extract comes from Indian gooseberries. It's included in BergaCor Plus because the evidence suggests it may help with acid reflux (GERD) and cholesterol levels.
Can I take this if I'm on a blood thinner or aspirin?
Not without checking first. Amla extract in this product may increase bleeding risk when combined with blood thinners or aspirin. Talk to your doctor or pharmacist before starting BergaCor Plus.
Does this product help with high cholesterol?
Yes, possibly. Both amla extract and bergamot extract are rated possibly effective for high cholesterol and related lipid problems based on the evidence we have.
What side effects have been reported?
In clinical trials, a small number of people reported stomach upset or indigestion with amla. One person reported heartburn with bergamot. A few others reported fatigue or muscle and joint pain. Topical bergamot can cause skin reactions and photosensitivity.
Is it safe to use during pregnancy or breastfeeding?
The safety data advises against it. There isn't enough reliable information for either amla or bergamot during pregnancy or breastfeeding. Talk with your doctor or pharmacist if you're pregnant, planning pregnancy, or nursing.
Does bergamot in this product cause sun sensitivity?
Bergamot contains a compound called bergapten that can make skin more sun-sensitive. If you're taking drugs that already increase sun sensitivity, combining them with this product could increase that risk. Check with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BergaCor Plus is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BergaCor Plus label
Sources

Sources & How We Checked

BergaCor Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Indian Gooseberry 6 references
  1. Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
  2. Fatima N, Pingali U, Muralidhar N. Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus. Phytomedicine. 2014;21(5):579-85. PubMed
  3. Shanmugarajan D, Girish C, Harivenkatesh N, Chanaveerappa B, Prasanna Lakshmi NC. Antihypertensive and pleiotropic effects of Phyllanthus emblica extract as an add-on therapy in patients with essential hypertension-A randomized double-blind placebo-contro
  4. Akhtar MS, Ramzan A, Ali A, Ahmad M. Effect of amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr. 2011;62(6):609-16.
  5. Usharani P, Fatima N, Muralidhar N. Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study. Diabetes Metab Syndr Obes. 20 PubMed
  6. Majeed M, Mundkur L, Paulose S, Nagabhushanam K. Novel Emblica officinalis extract containing ß-glucogallin vs. metformin: a randomized, open-label, comparative efficacy study in newly diagnosed type 2 diabetes mellitus patients with dyslipidemia. Food Fu

See these in context on the Indian Gooseberry monograph →

Bergamot 17 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . PubMed
  4. Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J.Am.Acad.Dermatol. 2001;45(3):458-461. PubMed
  5. Finsterer, J. Earl Grey tea intoxication. Lancet 4-27-2002;359(9316):1484. PubMed
  6. Gruson, L. M. and Chang, M. W. Berloque dermatitis mimicking child abuse. Arch.Pediatr.Adolesc.Med. 2002;156(11):1091-1093. PubMed
  7. Weisenseel, P. and Woitalla, S. [Toxic mustard plaster dematitis and phototoxic dematitis after application of bergamot oil]. MMW.Fortschr.Med. 12-15-2005;147(51-52):53, 55.
  8. Placzek, M., Fromel, W., Eberlein, B., Gilbertz, K. P., and Przybilla, B. Evaluation of phototoxic properties of fragrances. Acta Derm.Venereol. 2007;87(4):312-316. PubMed
  9. Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. F PubMed
  10. Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil. Effects of a cinnamate sunscreen. J.Photochem.Photobiol.B 1990;7(2-4):199-208. PubMed
  11. Young, A. R., Walker, S. L., Kinley, J. S., Plastow, S. R., Averbeck, D., Morliere, P., and Dubertret, L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model. J.P PubMed
  12. Girard, J., Unkovic, J., Delahayes, J., and Lafille, C. [Phototoxicity of Bergamot oil. Comparison between humans and guinea pigs]. Dermatologica 1979;158(4):229-243.
  13. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives. Contact Dermatitis 1977;3(5):225-23 PubMed
  14. Zacher, K. D. and Ippen, H. [Contact dermatitis caused by bergamot oil]. Derm.Beruf.Umwelt. 1984;32(3):95-97.
  15. Yasui, Y. and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting. J.Dermatol. 1994;21(5):319-322. PubMed
  16. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. I. Characterization and quantification of the photoactive component. Br.J.Dermatol. 1977;96(5):475-482. PubMed
  17. Bruno A, Pandolfo G, Crucitti M, Cedro C, Zoccali RA, Muscatello MRA. Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study. J Clin Psychopharmacol 2017;37(4):468-71. PubMed

See these in context on the Bergamot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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