No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Beta-Sitosterol 500 mg Ingredients & Drug Interactions

by Natures Craft

Capsule Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

Beta-Sitosterol 500 mg is a dietary supplement by Natures Craft with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, enlarged prostate (bph), heart health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Beta-Sitosterol 500 mg by Natures Craft

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: beta-sitosterol complex at 500 mg per capsule. Beta-sitosterol is a naturally occurring plant sterol — a fat-like compound found in plants — that your body uses to help manage cholesterol levels and support prostate health.

The capsule itself is made from gelatin and filled with microcrystalline cellulose, vegetable magnesium stearate, and silicon dioxide to keep everything stable and easy to swallow.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Beta-sitosterol's overall clinical evidence instead.

Strong

Strong clinical evidence supports Beta-sitosterol for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Benign prostatic hyperplasia (BPH) — rated "Likely Effective" (Natural Medicines).
  • On file: Coronary heart disease (CHD) — rated "Possibly Effective" (Natural Medicines).
  • On file: Familial hypercholesterolemia — rated "Possibly Effective" (Natural Medicines).

Beta-sitosterol is likely effective for benign prostatic hyperplasia (BPH) — the non-cancerous enlargement of the prostate gland that causes trouble with urination as men age. For familial hypercholesterolemia (a genetic condition that raises cholesterol) and coronary heart disease, the evidence suggests it's possibly effective.

The data we hold doesn't establish effectiveness for any other uses.

The evidence, ingredient by ingredient Beta-sitosterol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-sitosterol is generally well tolerated when taken by mouth short-term. The most common side effects are mild digestive ones: constipation, diarrhea, gas, indigestion, and nausea.

A small number of users have reported reduced appetite. There's also a single case report of acute inflammation of the pancreas (pancreatitis) in someone who started the supplement, though it went away when he stopped taking it.

The safety data is not strong enough to recommend this during pregnancy or breastfeeding, so avoid it if you're pregnant or nursing. Talk with your doctor or pharmacist if you're planning to take it and either of these applies to you.

Side effects, ingredient by ingredient Beta-sitosterol

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for beta-sitosterol. Still, mention this supplement to your doctor or pharmacist before you take it, especially if you're on any cholesterol or blood pressure medication.

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Beta-sitosterol is a solid choice if you're looking to support prostate health or manage cholesterol, especially if you have genetic high cholesterol or established heart disease. Most people tolerate it well, though mild digestive upset can happen.

If you're pregnant, breastfeeding, or take any medications, check with your own doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beta-Sitosterol 500 mg, straight from the product label.

Brand Natures Craft
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Nov 19, 2021
DSLD ID 256254
Product type Fat/fatty Acid
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beta-Sitosterol 500 mg by Natures Craft, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
IngredientAmount% DV
Beta-Sitosterol Complex500 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Vegetable Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: 1 capsule taken 1 to 2 times daily preferably with meals or as directed by a healthcare professional.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Nature at its finest

Please recycle.

Formula

500 mg complex

Formulation

Support healthy cholesterol levels already within the normal range Support cardiovascular health

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Formulated in the U.S.A. Good Manufacturing Practice Sourced from a GMP Certified Facility Quality Assured

See for yourself

Beta-Sitosterol 500 mg by Natures Craft label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Beta-Sitosterol 500 mg by Natures Craft

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Beta-Sitosterol Complex

No known
interactions
500 mg per serving

Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Eviden...

Beta-Sitosterol Complex monograph & interactions

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Vegetable Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beta-Sitosterol 500 mg by Natures Craft Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Beta-Sitosterol 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Beta-Sitosterol 500 mg, from the product label.

Natures Craft

See all Natures Craft products
Name
Nature's Craft
City
Monsey
State
NY
ZipCode
10952
Phone Number
408-599-3841
Web Address
shopnaturescraft.com
Pharmacist Counseling Corner

Beta-Sitosterol 500 mg by Natures Craft: Common Questions

Does Beta-Sitosterol 500 mg by Natures Craft interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Beta-Sitosterol 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Beta-Sitosterol 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is beta-sitosterol, and why is it in this supplement?
Beta-sitosterol is a plant sterol — a naturally occurring fat-like substance from plants — that helps manage cholesterol and supports prostate health. Research shows it's likely to help with enlarged prostate and possibly helpful for high cholesterol and heart disease.
What are the most common side effects?
Digestive upset is the main thing to watch for: constipation, diarrhea, gas, indigestion, nausea, and sometimes reduced appetite. Most people don't experience these, and they're usually mild.
Can I take this if I'm pregnant or breastfeeding?
The safety data isn't strong enough to recommend it during pregnancy or breastfeeding. Talk with your doctor or pharmacist about whether it's right for you in either situation.
Can beta-sitosterol affect my acne?
Yes — beta-sitosterol taken by mouth can worsen acne in some people, especially when combined with saw palmetto. If you have acne-prone skin, mention this to your doctor or pharmacist before starting.
Does this interact with my medications?
No interactions are documented in our data for beta-sitosterol. That said, it's always worth mentioning any supplement to your doctor or pharmacist, particularly if you take cholesterol or blood pressure drugs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beta-Sitosterol 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beta-Sitosterol 500 mg label
Go deeper

The Full Monographs Behind Beta-Sitosterol 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Beta-Sitosterol 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-sitosterol 7 references
  1. Berges RR, Windeler J, Trampisch HJ, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet 1995;345:1529-32.
  2. Klippel KF, Hiltl DM, Schipp B. A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. Br J Urol 1997;80:427-32.
  3. Wilt TJ, MacDonald R, Ishani A. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int 1999;83:976-83. PubMed
  4. Oster P, Schlierf G, Heuck CC, et al. [Sitosterol in familial hyperlipoproteinemia type II. A randomized, double-blind, cross-over study]. Dtsch Med Wochenschr 1976;101:1308-11.
  5. Becker M, Staab D, Von Bergman K. Long-term treatment of severe familial hypercholesterolemia in children: effect of sitosterol and bezafibrate. Pediatrics 1992;89:138-42. DOI
  6. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  7. Lorenze A, Hsueh W, Nasr J. Beta-sitosterol-induced acute pancreatitis: A case report and review of the literature. Cureus. 2020;12(3):e7407. PubMed

See these in context on the Beta-sitosterol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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