Beta-Sitosterol Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Beta-Sitosterol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Beta-Sitosterol is a dietary supplement by Pure Encapsulations with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, enlarged prostate (bph), heart health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Beta-Sitosterol by Pure Encapsulations
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: beta-sitosterol, a plant sterol that your body can absorb from foods and supplements. It's thought to work by competing with dietary cholesterol for absorption in your gut, which may help lower cholesterol levels.
The capsule itself contains inactive ingredients — hypoallergenic plant fiber, cellulose, water, and ascorbyl palmitate — that help hold everything together.
Does it work?
Strong evidence
Beta-sitosterol is likely effective for benign prostatic hyperplasia (BPH), a common condition where the prostate gland enlarges in older men. It's possibly effective for familial hypercholesterolemia (a genetic cholesterol condition) and coronary heart disease (CHD).
The evidence for cholesterol and heart health is there, but it's not as strong as it is for BPH.
How safe is it?
Well-documented data
Beta-sitosterol is generally well tolerated when taken by mouth short-term. The most common side effects are constipation, diarrhea, gas, indigestion, and nausea.
A small number of people report reduced appetite, and there's one case report of acute pancreatitis thought to be linked to this supplement — symptoms started on day one but didn't return when the person stopped. There's also a note that beta-sitosterol alone, or combined with saw palmetto, can worsen acne in some people.
There isn't enough safety data to know whether it's safe during pregnancy or breastfeeding. If you're pregnant or nursing, talk with your doctor or pharmacist before taking it.
Meds to double-check
No known interactions
No interactions are documented in our data for beta-sitosterol. Even so, run your current medications through the search tool below before you start — it's the safest way to confirm.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.
Beta-sitosterol may help if you have an enlarged prostate or high cholesterol, especially if cholesterol runs in your family. Most people tolerate it well, though digestive side effects like bloating or loose stool can happen.
If you're pregnant, nursing, or take any medications, check with your doctor or pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Beta-Sitosterol, straight from the product label.
| Brand | Pure Encapsulations |
|---|---|
| Barcode (UPC) | 766298005485 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2023 |
| DSLD ID | 293905 |
| Product type | Fat/fatty Acid |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Beta-Sitosterol by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Beta-Sitosterol | 60 mg | -- |
Other ingredients: hypoallergenic Plant Fiber, Cellulose, Water, Ascorbyl Palmitate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage
Store in a cool, dry place.
Suggested/Recommended/Usage/Directions
Recommendations: As a dietary supplement, take 1 capsule, 1-2 times daily, with meals.
Precautions
Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
Keep out of the reach of children.
Use only if safety seal is intact.
Contains: Soy
General Statements
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements
Formulation
Certified gluten-free by the Gluten-Free Certification Organization, www.gluten.org
Supports prostate health
Gluten-free & Non-GMO
Seals/Symbols
GFCO.org (Gluten-Free Certification Organization)
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Beta-Sitosterol by Pure Encapsulations label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Beta-Sitosterol by Pure Encapsulations
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Beta-Sitosterol
No knowninteractions
Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Eviden...
Beta-Sitosterol monograph & interactionsOther (inactive) ingredients: Hypoallergenic Plant Fiber, Cellulose, Water, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.
Beta-Sitosterol by Pure Encapsulations Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Beta-Sitosterol. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Beta-Sitosterol, from the product label.
Pure Encapsulations
See all Pure Encapsulations products- Name
- Pure Encapsulations
- Street Address
- 490 Boston Post Road
- City
- Sudbury
- State
- MA
- Phone Number
- 1-800-753-2277
- Web Address
- www.PureEncapsulations.com
Beta-Sitosterol by Pure Encapsulations: Common Questions
Does Beta-Sitosterol by Pure Encapsulations interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What's beta-sitosterol and why is it in this supplement?
Will this help my cholesterol or prostate?
What side effects should I watch for?
Is it safe to take while pregnant or breastfeeding?
Can I take this with my other medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Beta-Sitosterol is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Beta-Sitosterol’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Beta-Sitosterol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Beta-sitosterol 7 references
- Berges RR, Windeler J, Trampisch HJ, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet 1995;345:1529-32.
- Klippel KF, Hiltl DM, Schipp B. A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. Br J Urol 1997;80:427-32.
- Wilt TJ, MacDonald R, Ishani A. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int 1999;83:976-83. PubMed
- Oster P, Schlierf G, Heuck CC, et al. [Sitosterol in familial hyperlipoproteinemia type II. A randomized, double-blind, cross-over study]. Dtsch Med Wochenschr 1976;101:1308-11.
- Becker M, Staab D, Von Bergman K. Long-term treatment of severe familial hypercholesterolemia in children: effect of sitosterol and bezafibrate. Pediatrics 1992;89:138-42. DOI
- Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
- Lorenze A, Hsueh W, Nasr J. Beta-sitosterol-induced acute pancreatitis: A case report and review of the literature. Cureus. 2020;12(3):e7407. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC