No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Maca-3 Ingredients & Drug Interactions

by Pure Encapsulations

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Maca-3 is a dietary supplement by Pure Encapsulations with 3 active ingredients. Its ingredients are commonly taken for low libido and sexual function, energy and stamina, menopause symptoms.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Maca-3 by Pure Encapsulations

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Maca-3 has 3 active ingredients, all maca tuber extract — the same ingredient listed three times. Maca is a root vegetable native to Peru, used in traditional medicine for centuries.

The capsules also contain inactive ingredients: cellulose, water, plant fiber, and ascorbyl palmitate (a form of vitamin C used as a preservative).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Maca product and its label doesn't state a use — see Maca's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence on maca for conditions like irregular periods (amenorrhea), anemia, sexual side effects from antidepressants, athletic performance, and bone health is insufficient. That means studies haven't given us clear answers yet about whether it works for any of these.

We hold no effectiveness data beyond that.

The evidence, ingredient by ingredient Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Maca is generally well tolerated when you eat it as food, but long-term safety at supplement doses hasn't been well studied. The safety data advises against maca during pregnancy and while breastfeeding because there isn't enough reliable information.

Fresh, uncooked maca may cause stomach pain in some people.

Side effects, ingredient by ingredient Maca

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the maca tuber extract in this product. That said, always run your full medication list through the checker on this page before you start, and confirm with your own doctor or pharmacist.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Maca-3 is a straightforward maca extract supplement with no documented drug interactions in our records. Its real-world benefits for the conditions it's marketed for aren't yet proven.

If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before using this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Maca-3, straight from the product label.

Brand Pure Encapsulations
Barcode (UPC) 766298010557
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 303983
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Maca-3 by Pure Encapsulations, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
766298010557
IngredientAmount% DV
Maca Tuber Extract225 mg--
Maca Tuber Extract225 mg--
Maca Tuber Extract100 mg--

Other ingredients: Cellulose, Water, Plant Fiber, Ascorbyl Palmitate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement, take 1 capsule, 1-2 times daily, with or between meals.

Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our hypoallergenic supplements.

Formulation

GFCO.org (Gluten-Free Certification Organization) Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Supports healthy libido

Gluten-free, non-GMO & Hypoallergenic

Gluten-free, non-GMO & Hypoallergenic

Seals/Symbols

GFCO.org (Gluten-Free Certification Organization)

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Maca-3 by Pure Encapsulations label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Maca-3 by Pure Encapsulations

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Maca Tuber Extract

No known
interactions
225 mg per serving Form: Macaenes, Macamides

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca Tuber Extract monograph & interactions

Maca Tuber Extract

No known
interactions
225 mg per serving Form: Glucosinolates

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca Tuber Extract monograph & interactions

Maca Tuber Extract

No known
interactions
100 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca Tuber Extract monograph & interactions

Other (inactive) ingredients: Cellulose, Water, Plant Fiber, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Maca-3 by Pure Encapsulations Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Maca-3. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Maca-3, from the product label.

Pure Encapsulations

See all Pure Encapsulations products
Name
Pure Encapsulations
Street Address
490 Boston Post Road
City
Sudbury
State
MA
Phone Number
1-800-753-2277
Web Address
www.PureEncapsulations.com
Pharmacist Counseling Corner

Maca-3 by Pure Encapsulations: Common Questions

Does Maca-3 by Pure Encapsulations interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Maca-3. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Maca-3 contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is maca safe to take while pregnant?
No. The safety data advises against maca during pregnancy because there isn't enough reliable information. If you're pregnant or planning to become pregnant, talk with your doctor or pharmacist before taking this product.
Is maca safe while breastfeeding?
There isn't enough reliable information on safety while breastfeeding. Avoid it unless your doctor or pharmacist has cleared it for you.
Can maca cause side effects?
Fresh, uncooked maca may cause stomach pain. The product is generally well tolerated when used as a food, but long-term safety at supplement doses hasn't been studied thoroughly.
Does maca actually work for irregular periods, low energy, or sexual function?
The evidence isn't established yet. We have insufficient reliable evidence to rate maca for irregular periods, anemia, sexual side effects from antidepressants, athletic performance, or bone health.
What is maca?
Maca is a root vegetable from Peru that's been used in traditional medicine for a long time. This product contains maca tuber extract in capsule form, along with cellulose, water, plant fiber, and a preservative.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Maca-3 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Maca-3 label
Go deeper

The Full Monographs Behind Maca-3’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Maca-3's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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