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Dietary supplement

Bilberry 60 mg Ingredients & Drug Interactions

by Botanic Choice

Bilberry 60 mg label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bilberry 60 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bilberry 60 mg is a dietary supplement by Botanic Choice with 1 active ingredient. Its ingredients are commonly taken for eye and vision health, antioxidant support, diarrhea and digestive upset.Based on those ingredients, 275 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are MirtoSelect Bilberrry extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bilberry 60 mg by Botanic Choice

Ask about any prescription or over-the-counter medication and we check it for interactions with Bilberry 60 mg by Botanic Choice — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bilberry 60 mg by Botanic Choice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This tablet contains one active ingredient: MirtoSelect Bilberry extract at 60 mg per dose. Bilberry is a dark purple fruit related to blueberry, and the extract concentrates its natural compounds.

The tablet also includes several inactive ingredients—dicalcium phosphate, microcrystalline cellulose, stearic acid, magnesium stearate, silicon dioxide, and an aqueous film coating—which are standard binders, fillers, and capsule materials.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Antioxidant protection for eye and vision health.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Diabetic retinopathy, Dry eye, Glaucoma — and 4 related terms.
  • The closest evidence on file: Bilberry is rated "Possibly Ineffective" for Night vision (Natural Medicines).
  • Also on file: Bilberry is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD), Cataracts, Diabetic retinopathy, Dry eye, and more.

The evidence for bilberry's effectiveness is mixed and often limited. Night vision—probably the most common reason people try bilberry—is rated Possibly Ineffective, meaning the science doesn't support the claim.

For age-related cognitive decline, age-related macular degeneration (AMD), atherosclerosis, high cholesterol (hyperlipidemia), and chronic venous insufficiency, there simply isn't enough reliable evidence in our data to rate whether it works or not. If you're considering bilberry for one of these uses, talk it over with your doctor to see whether the available evidence makes sense for your situation.

The evidence, ingredient by ingredient Bilberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bilberry fruit as a food is generally well tolerated, but the safety data for concentrated supplements like this one is limited and long-term safety isn't well established. The most common side effects are dark-colored stools (which can look black or dark green—a harmless staining effect), flatulence, and mild stomach discomfort.

In small trials, these GI effects occurred in a small number of participants. Your tongue and teeth may also temporarily darken.

Overall, orally taken bilberry extract seems generally well tolerated, but the evidence base is modest.

Side effects, ingredient by ingredient Bilberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bilberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 275 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you're on blood thinners or antiplatelet drugs like warfarin or aspirin (Moderate risk of increased bleeding), diabetes medications (Moderate risk of low blood sugar), erlotinib/Tarceva (Moderate risk of reduced cancer drug effectiveness), or drugs metabolized by the CYP2E1 liver enzyme (Moderate risk the bilberry may make them less effective). If you're unsure whether any of your medications fall into these groups, use the interaction checker on this page or ask your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Bilberry extract might appeal to you if you're looking for an antioxidant supplement, but the evidence for its marketed benefits—especially night vision—is weak. If you take blood thinners, diabetes medications, cancer drugs like erlotinib, or certain other prescription medications, you'll need to check with your own doctor or pharmacist first; bilberry could interfere with how they work.

Expect some harmless darkening of your stools and tongue. Given the limited long-term safety data, talk it over with your healthcare provider to decide if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bilberry 60 mg, straight from the product label.

Brand Botanic Choice
Barcode (UPC) 703308020366
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Dec 22, 2017
DSLD ID 77400
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bilberry 60 mg by Botanic Choice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
30
UPC/BARCODE
703308020366
IngredientAmount% DV
MirtoSelect Bilberrry extract120 mg--

Other ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Stearic Acid, Magnesium Stearate, Silicon Dioxide, Aqueous Film Coating

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Herbal Supplement

General Statements

Trusted since 1910 Essential Antioxidant protection

Actual pill size

Formula

Standardized extract - 36 % anthocyanosides

Formulation

Gluten free

Brand IP Statement(s)

Mirtoselect an Indena product

Mirtoselect is a registered trademark of Indena S.p.A.

IBG Indiana Botanic Gardens

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1-2 tablets twice daily, as a dietary supplement, or as directed by a physician.

Precautions

Warning: If you are taking any medications or are pregnant or nursing, do not use prior to consulting a physician.

For your protection, this container has an outer safety seal. (Do not accept if missing or broken.)

Keep out of reach of children

FDA Disclaimer Statement

This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a dry, cool place.

General

C-105444

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bilberry 60 mg by Botanic Choice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bilberry 60 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bilberry 60 mg by Botanic Choice

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

MirtoSelect Bilberrry extract

Interacts with
275 drugs
120 mg per serving Form: Anthocyanidins, Anthocyanosides

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye healt...

MirtoSelect Bilberrry extract monograph & interactions

Other (inactive) ingredients: Dicalcium Phosphate, Microcrystalline Cellulose, Stearic Acid, Magnesium Stearate, Silicon Dioxide, Aqueous Film Coating. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bilberry 60 mg by Botanic Choice Drug Interactions

Want to check YOUR meds against Bilberry 60 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
275Drugs
275 Moderate

Ingredients driving the most interactions

MirtoSelect Bilberrry extract 275

Individual Drug Interactions

The ingredients in Bilberry 60 mg interact with 275 drugs. Click any drug to see the details.

1 of the 1 ingredient in Bilberry 60 mg interact with drugs. Each result below shows which ingredient is responsible. MirtoSelect Bilberrry extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Bilberry 60 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

MirtoSelect Bilberrry extract4 drug types · 275 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Erlotinib (Tarceva)

Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.

Likelihood Possible Evidence D
MirtoSelect Bilberrry extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bilberry 60 mg, from the product label.

Botanic Choice

See all Botanic Choice products
Name
Indiana Botanic Gardens, Inc.
Street Address
3401 W. 37th Ave.
City
Hobart
State
IN
ZipCode
46342
Phone Number
1-800-644-8327
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Bilberry 60 mg by Botanic Choice: Common Questions

Does Bilberry 60 mg by Botanic Choice interact with any medications?
Yes. Based on its ingredients, Bilberry 60 mg has a known interaction with 275 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bilberry 60 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does bilberry really help your night vision?
Night vision is rated Possibly Ineffective in our data, meaning the evidence doesn't back up that claim. Bilberry is commonly sold for this purpose, but scientific studies haven't shown it works for improving how you see in dim light.
What are the most common side effects?
Most people tolerate bilberry well orally. The most common side effects are dark-colored stools (harmless staining from the pigment), flatulence, and mild stomach discomfort. Your tongue may also temporarily darken, and in rare cases, slight tooth discoloration has been noted.
Is this safe to take if I'm pregnant or breastfeeding?
Bilberry fruit is rated Likely Safe during pregnancy and lactation based on available data. Of course, any supplement decision during pregnancy or nursing should be discussed with your doctor or midwife first.
Can I take this with my other supplements or vitamins?
We only hold interaction data for prescription and over-the-counter medications in our database, not for other supplements or vitamins. If you're combining multiple supplements, ask your pharmacist or doctor to review them together for safety.
Why is the safety data for bilberry supplements limited if it's a common food?
Bilberry as a regular fruit eaten in normal amounts is generally recognized as safe, but concentrated supplements are a different story—they deliver much higher doses, and long-term safety studies for those doses are lacking. That's why the caution is stronger for supplement use.
Will this stain my clothes or mouth permanently?
No. The dark discoloration from bilberry's natural pigments is temporary and harmless. It may darken your stools and tongue while you're taking it, but it washes out and doesn't stain permanently.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bilberry 60 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bilberry 60 mg label
Go deeper

The Full Monographs Behind Bilberry 60 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bilberry

Interacts with 275 drugs

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye health, circulation, and mild diarrhea. While...

Read the full Bilberry monograph →
Sources

Sources & How We Checked

Bilberry 60 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bilberry 14 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Morazzoni P, Magistretti MJ. Activity of Myrtocyan, an anthosyanoside complex from Vaccinium myrtillus (VMA), on platelet aggregation and adhesiveness. Fitoterapia 1990;61:13-21.
  3. Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., and Jula, A. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr 2008;87(2):323-331. PubMed
  4. Hawrelak, J. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. J Altern Complement Med 2010;16(10):1065-1071. PubMed
  5. Morazzoni P and Magistretti MJ. Effects of Vaccinium myrtillus anthocyanosides on prostacyclin-like activity in rat arterial issue. Fitoterapia 1986;57:11-14.
  6. Pulliero G, Montin S, Bettini V, and et al. Ex vivo study of the inhibitory effects of Vaccinium myrtillus anthocyanosides on human platelet aggregation. Fitoterapia 1989;60:69-75.
  7. Bottecchia D. Preliminary report on the inhibitory effect of vaccinium myrtillus anthocyanosides on platelet aggregation and clot retraction. Fitoterapia 1987;48:3-8.
  8. Fdez, M., Zaragoza, F., and Alvarez, P. In vitro platelet aggregation effects of anthocyanosides of vaccinium myrtilus L. Anales de la Real Academia de Farmacia 1983;49:79-90.
  9. Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis-an open pilot study. 2013 May;7(4):271-9. PubMed
  10. Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst J, Russell W, et al. A single supplement of a standardized bilberry (Vaccinium myrtillus L.) extract (36% wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes control
  11. Aichinger G, Pahlke G, Nagel LJ, Berger W, Marko D. Bilberry extract, its major phenolic compounds, and soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells. Food Funct 2016;7(8):3628-36.
  12. Prokop J, Lněničková K, Cibicek N, et al. Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats. Food Chem Toxicol 2019;129:382-90. PubMed
  13. Chan SW, Chu TTW, Choi SW, Benzie IFF, Tomlinson B. Impact of short-term bilberry supplementation on glycemic control, cardiovascular disease risk factors, and antioxidant status in Chinese patients with type 2 diabetes. Phytother Res 2021. Online ahead o PubMed
  14. Bøhn SK, Myhrstad MCW, Thoresen M, et al. Bilberry/red grape juice decreases plasma biomarkers of inflammation and tissue damage in aged men with subjective memory impairment -a randomized clinical trial. BMC Nutr 2021;7(1):75. PubMed

See these in context on the Bilberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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