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Dietary supplement

Butcher's Broom 4:1 Extract 110 mg Ingredients & Drug Interactions

by Botanic Choice

Butcher's Broom 4:1 Extract 110 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Butcher's Broom 4:1 Extract 110 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Butcher's Broom 4:1 Extract 110 mg is a dietary supplement by Botanic Choice with 2 active ingredients. Its ingredients are commonly taken for chronic venous insufficiency, varicose veins, leg swelling and heaviness.Based on those ingredients, 158 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Butcher's Broom 4:1 extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Butcher's Broom 4:1 Extract 110 mg by Botanic Choice

Ask about any prescription or over-the-counter medication and we check it for interactions with Butcher's Broom 4:1 Extract 110 mg by Botanic Choice — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Butcher's Broom 4:1 Extract 110 mg by Botanic Choice

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients, both forms of butcher's broom extract — a 4:1 concentrated extract at 110 mg per capsule, and a second butcher's broom extract. Butcher's broom is a plant used traditionally for vein and circulation issues.

The capsule also contains inactive ingredients: rice flour, gelatin, magnesium stearate, and maltodextrin.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Circulation support.
  • We looked for evidence on: Chronic venous insufficiency (CVI), Varicose veins, Hemorrhoids, Leg edema, Venous insufficiency.
  • The strongest evidence on file: Butcher's Broom is rated "Possibly Effective" for Chronic venous insufficiency (CVI) (Natural Medicines).
  • Also on file: Butcher's Broom is rated "Insufficient Reliable Evidence To Rate" for Hemorrhoids, Varicose veins.

Butcher's broom is possibly effective for chronic venous insufficiency (CVI) — a condition where veins in your legs have trouble returning blood upward and you get heaviness, swelling, or aching. The evidence for other uses listed — diabetic retinopathy (damage to blood vessels in the eye), hemorrhoids, orthostatic low blood pressure (dizziness on standing), and lymphedema (fluid buildup) — is insufficient to say whether it works.

The evidence, ingredient by ingredient Butcher's Broom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term, butcher's broom is generally well tolerated in most healthy adults, but long-term safety data are limited. Common side effects taken by mouth are nausea, vomiting, diarrhea, heartburn, indigestion, and stomach irritation.

One case report described severe vomiting and diarrhea leading to hospitalization. If applied to skin, it may cause contact dermatitis (allergic rash) in sensitive people.

The safety data advises against use during pregnancy because it hasn't been established. There isn't enough safety information to use it while breastfeeding either — talk with your doctor or pharmacist about personalized advice if you're pregnant or nursing.

Side effects, ingredient by ingredient Butcher's Broom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Butcher's Broom.
  • The most serious interaction on file is rated Moderate.
  • For scale: 158 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check whether you're on any alpha-adrenergic antagonists (like doxazosin for high blood pressure or prostate problems) or alpha-adrenergic agonists (like phenylephrine in decongestants or some blood pressure and ADHD drugs). Both types can have Moderate interactions with butcher's broom.

Use the medication checker below to confirm your specific prescriptions and over-the-counter drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Consider butcher's broom if you have chronic venous insufficiency and want a plant-based option — it's possibly effective for that one use. Be careful if you take any alpha-adrenergic medications (for blood pressure, nasal congestion, or prostate issues); check your exact drugs with your doctor or pharmacist first.

Don't use it during pregnancy or breastfeeding without professional guidance. Talk it over with your own healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Butcher's Broom 4:1 Extract 110 mg, straight from the product label.

Brand Botanic Choice
Barcode (UPC) 703308030990
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 193336
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Butcher's Broom 4:1 Extract 110 mg by Botanic Choice, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
703308030990
IngredientAmount% DV
Butcher's Broom 4:1 extract103.75 mg--
Butcher's Broom extract110 mg--

Other ingredients: Rice Flour, Gelatin Capsule, Magnesium Stearate, Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

General Statements

Trusted since 1910 Essentials

Circulation support

Formulation

Gluten free Non GMO

Seals/Symbols

Gluten free Non GMO

Suggested/Recommended/Usage/Directions

Suggested Use: Take one (1) capsule daily, with a meal, as a dietary supplement, or as directed by a qualified health care professional.

Precautions

Warning: If you are taking any medications or are pregnant or nursing do not use prior to consulting a physician.

For your protection, this container has an outer safety seal. (Do not accept if missing or broken.)

Keep out of reach of children

FDA Disclaimer Statement

This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a dry, cool place.

Brand IP Statement(s)

IBG Indiana Botanic Gardens

General

C-107728

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Butcher's Broom 4:1 Extract 110 mg by Botanic Choice label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Butcher's Broom 4:1 Extract 110 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Butcher's Broom 4:1 Extract 110 mg by Botanic Choice

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Butcher's Broom 4:1 extract

Interacts with
158 drugs
103.75 mg per serving

Butcher's broom is a plant extract most often used for circulation problems in the legs, such as chronic venous insufficiency, where some evidence sug...

Butcher's Broom 4:1 extract monograph & interactions

Butcher's Broom extract

Interacts with
158 drugs
110 mg per serving Form: Ruscogenins

Butcher's broom is a plant extract most often used for circulation problems in the legs, such as chronic venous insufficiency, where some evidence sug...

Butcher's Broom extract monograph & interactions

Other (inactive) ingredients: Rice Flour, Gelatin Capsule, Magnesium Stearate, Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Butcher's Broom 4:1 Extract 110 mg by Botanic Choice Drug Interactions

Want to check YOUR meds against Butcher's Broom 4:1 Extract 110 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
158Drugs
158 Moderate

Ingredients driving the most interactions

Butcher's Broom 4:1 extract 158

Individual Drug Interactions

The ingredients in Butcher's Broom 4:1 Extract 110 mg interact with 158 drugs. Click any drug to see the details.

1 of the 2 ingredients in Butcher's Broom 4:1 Extract 110 mg interact with drugs. Each result below shows which ingredient is responsible. Butcher's Broom 4:1 extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Butcher's Broom 4:1 Extract 110 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Butcher's Broom 4:1 extract2 drug types · 158 drugs

Alpha-Adrenergic Agonists

Theoretically, butcher's broom might increase the effects and adverse effects of alpha-adrenergic agonists.
Animal and in vitro studies show that butcher's broom has alpha-adrenergic agonist effects.

Likelihood Possible Evidence D
Alpha-Adrenergic Antagonists

Theoretically, butcher's broom might reduce the effects of alpha-adrenergic antagonists.
Animal and in vitro studies show that butcher's broom has alpha-adrenergic agonist effects.

Likelihood Possible Evidence D
Butcher's Broom 4:1 extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Butcher's Broom 4:1 Extract 110 mg, from the product label.

Botanic Choice

See all Botanic Choice products
Name
Indiana Botanic Gardens, Inc.
Street Address
3401 W. 37th Ave.
City
Hobart
State
IN
ZipCode
46342
Phone Number
1-800-644-8327
Web Address
www.botanicchoice.com
Pharmacist Counseling Corner

Butcher's Broom 4:1 Extract 110 mg by Botanic Choice: Common Questions

Does Butcher's Broom 4:1 Extract 110 mg by Botanic Choice interact with any medications?
Yes. Based on its ingredients, Butcher's Broom 4:1 Extract 110 mg has a known interaction with 158 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Butcher's Broom 4:1 Extract 110 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take butcher's broom if I'm pregnant?
No. Safety has not been established during pregnancy, and the data advise against it. Talk with your doctor or pharmacist for personalized advice if you're pregnant or planning to become pregnant.
Can I take this while breastfeeding?
There isn't enough safety information to recommend it while breastfeeding. Check with your doctor or pharmacist to figure out what's right for you and your baby.
What are the side effects I should watch for?
Most common side effects taken by mouth are nausea, vomiting, diarrhea, heartburn, indigestion, and stomach irritation. These are usually mild and short-term. If you apply it to your skin, it may cause a rash in sensitive people. If you notice severe symptoms like vomiting with dehydration, seek medical help right away.
Does butcher's broom actually work for leg swelling and varicose veins?
It's possibly effective for chronic venous insufficiency — that heavy, achy feeling in your legs when veins aren't pumping blood back up efficiently. For other vein problems like hemorrhoids or pure cosmetic varicose veins, the evidence isn't strong enough to say.
How long should I take this?
The data show it's well tolerated short-term in most healthy people, but evidence on long-term safety is limited. Talk with your doctor or pharmacist about how long is safe for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Butcher's Broom 4:1 Extract 110 mg label
Go deeper

The Full Monographs Behind Butcher's Broom 4:1 Extract 110 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Butcher's Broom

Interacts with 158 drugs

Butcher's broom is a plant extract most often used for circulation problems in the legs, such as chronic venous insufficiency, where some evidence suggests it may help reduce swelling and di...

Read the full Butcher's Broom monograph →
Sources

Sources & How We Checked

Butcher's Broom 4:1 Extract 110 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Butcher's Broom 8 references
  1. Beltramino R, Penenory A, Buceta AM. An open-label, randomized multicenter study comparing the efficacy and safety of Cyclo 3 Fort versus hydroxyethyl rutoside in chronic venous lymphatic insufficiency. Angiology 2000;51:535-44.. PubMed
  2. Redman DA. Ruscus aculeatus (butcher's broom) as a potential treatment for orthostatic hypotension, with a case report. J Altern Complement Med 2000;6:539-49..
  3. Landa, N., Aguirre, A., Goday, J., Raton, J. A., and Diaz-Perez, J. L. Allergic contact dermatitis from a vasoconstrictor cream. Contact Dermatitis 1990;22(5):290-291. PubMed
  4. Cluzan, R. V., Alliot, F., Ghabboun, S., and Pascot, M. Treatment of secondary lymphedema of the upper limb with CYCLO 3 FORT. Lymphology 1996;29(1):29-35.
  5. Parrado F, Buzzi A. A study of the efficacy and tolerability of a preparation containing Ruscus aculeatus in the treatment of chronic venous insufficiency of the lower limbs. Clin Drug Invest 1999;18(4):255-61. DOI
  6. Sadarmin PP, Timperley J. An unusual case of Butcher's Broom precipitating diabetic ketoacidosis. J Emerg Med 2013;45(3):e63-e65. PubMed
  7. Ramirez-Hernandez M, Garcia-Selles J, Merida-Fernandez C, Martinez-Escribano JA. Allergic contact dermatitis to ruscogenins. Contact Dermatitis 2006;54(1):60. PubMed
  8. European Medicines Agency. Assessment report on Ruscus Aculeatus L rhizome. EMEA/HMPC/261939/2007. London, September 4, 2008. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_report/2009/12/WC500018288.pdf. Acces

See these in context on the Butcher's Broom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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