Major interaction on record — check this product against your medications before combining. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Bio-K Forte Caps Ingredients & Drug Interactions

by Biotics Research Corporation

Capsule Category: Other Combinations
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Bio-K Forte Caps is a dietary supplement by Biotics Research Corporation with 3 active ingredients. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Bio-K Forte Caps by Biotics Research Corporation

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Bio-K Forte Caps contains 3 active ingredients: Superoxide Dismutase, Catalase, and Vitamin K. Vitamin K is a fat-soluble vitamin that plays a central role in blood clotting and bone health.

The product also contains inactive ingredients — a capsule shell and magnesium stearate — that help deliver the actives.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: vitamin K for blood clotting and bone health.
  • We looked for evidence on: Hemorrhagic disease, Hypoprothrombinemia, Vitamin K-dependent clotting factors deficiency (VKCFD), Warfarin anticoagulation, Osteoporosis, vitamin K deficiency — and 1 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Hypoprothrombinemia, Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Effective" for Osteoporosis.

Vitamin K in this product is effective for treating vitamin K deficiency and supporting normal blood clotting. It's also possibly effective for bone health and osteoporosis.

We don't have effectiveness data on file for Superoxide Dismutase or Catalase, so we can't speak to what those ingredients do in this formulation.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin K taken by mouth is generally well tolerated in healthy people at dietary levels. The most common side effects are mild gastrointestinal ones — nausea, stomach upset, and diarrhea.

Because vitamin K interacts with blood thinners, check with your doctor before taking a supplement, even though normal food sources are fine. Vitamin K is considered likely safe during pregnancy and while breastfeeding, but talk with your doctor or pharmacist about whether this product is right for you at that time.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or any other blood thinner, this product requires a conversation with your doctor or pharmacist first — vitamin K can reduce how well these medications work. For the other two ingredients in this formula, we hold no interaction data, so we can't check them against your medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Bio-K Forte Caps may be worth considering if you want vitamin K support and don't take blood thinners like warfarin. If you do take warfarin or any other blood thinner, or if you take any prescription medication, check with your doctor or pharmacist before starting this product.

We couldn't verify the safety or effects of the other two ingredients in the formula.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bio-K Forte Caps, straight from the product label.

Brand Biotics Research Corporation
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 21510
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bio-K Forte Caps by Biotics Research Corporation, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
IngredientAmount% DV
Superoxide Dismutase60 mcg--
Catalase60 mcg--
Vitamin K550 mcg688%

Other ingredients: Capsule shell, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

36583A JAN 14

Sealed with an imprinted safety seal for your protection.

Specially grown, biologically active vegetable culture containing naturally associated phytochemicals including polyphenolic compounds with SOD and catalase, dehydrated at low temperature to preserve associated enzyme factors.

Brand IP Statement(s)

(C) Copyright 2010

Suggested/Recommended/Usage/Directions

Recommendation: One (1) capsule each day as a dietary supplement or as otherwise directed by a healthcare professional.

Precautions

Caution: Those taking warfarin should avoid supplementation with Vitamin K unless specifically recommended and monitored by their physician. Pregnant and nursing mothers should avoid supplemental intakes higher that the RDA (65 mcg) unless specifically recommended and monitored by their physician.

KEEP OUT OF REACH OF CHILDREN

Storage

Store in a cool, dry area.

General

Rev. 10/10

FDA Statement of Identity

Dietary Supplement

Formula

Each capsule supplies Vitamin K as menaquinone-7 and phytonadione in a 1:10 ratio.

See for yourself

Bio-K Forte Caps by Biotics Research Corporation label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Bio-K Forte Caps by Biotics Research Corporation

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Superoxide Dismutase

60 mcg per serving

Catalase

60 mcg per serving

Vitamin K

Interacts with
2 drugs
550 mcg per serving Form: Menaquinone-7, Phytonadione

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K monograph & interactions

Other (inactive) ingredients: Capsule shell, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bio-K Forte Caps by Biotics Research Corporation Drug Interactions

Want to check YOUR meds against Bio-K Forte Caps?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Bio-K Forte Caps with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K1 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for Bio-K Forte Caps, from the product label.

Biotics Research Corporation

See all Biotics Research Corporation products
Name
BIOTICS RESEARCH CORP.
City
Rosenberg
State
Texas
Phone Number
(281) 344-0909
Pharmacist Counseling Corner

Bio-K Forte Caps by Biotics Research Corporation: Common Questions

Does Bio-K Forte Caps by Biotics Research Corporation interact with any medications?
Yes. Based on its ingredients, Bio-K Forte Caps has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bio-K Forte Caps contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this work if I'm low on vitamin K?
Yes — vitamin K is effective for treating vitamin K deficiency and supporting normal blood clotting. It may also help with bone health, though the evidence there is less established.
Can I take this if I'm on warfarin?
No — not without talking to your doctor first. Vitamin K directly weakens warfarin's ability to thin your blood. You need personalized guidance before taking any supplement with this ingredient.
What are the side effects?
Most side effects from oral vitamin K are mild and gastrointestinal — nausea, stomach upset, and diarrhea. Serious reactions are very rare. If you notice unusual symptoms, let your pharmacist or doctor know.
Is this safe during pregnancy?
Vitamin K is considered likely safe during pregnancy and breastfeeding, but talk with your doctor or pharmacist about whether this particular product is right for you before you take it.
What do Superoxide Dismutase and Catalase do?
We don't have effectiveness data on file for those ingredients in our system, so we can't tell you what role they're meant to play in this formula.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bio-K Forte Caps is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bio-K Forte Caps label
Sources

Sources & How We Checked

Bio-K Forte Caps's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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