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Dietary supplement

Bio-K-Mulsion Ingredients & Drug Interactions

by Biotics Research Corporation

Liquid Category: Vitamin
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Bio-K-Mulsion is a dietary supplement by Biotics Research Corporation with 1 active ingredient. Its ingredients are commonly taken for supporting normal blood clotting, bone health, heart and vascular health.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin K. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Bio-K-Mulsion by Biotics Research Corporation

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Bio-K-Mulsion is a single-ingredient liquid supplement containing vitamin K. Vitamin K plays a central role in blood clotting — your body uses it to make several clotting proteins — and also supports bone health.

The liquid is mixed with water, gum arabic, and sesame oil as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: vitamin k supplementation for blood clotting.
  • We looked for evidence on: Hemorrhagic disease, Hypoprothrombinemia, Intraventricular hemorrhage, Vitamin K-dependent clotting factors deficiency (VKCFD), Warfarin anticoagulation, Vitamin K deficiency — and 2 related terms.
  • The strongest evidence on file: Vitamin K is rated "Effective" for Hemorrhagic disease (Natural Medicines).
  • Also on file: Vitamin K is rated "Effective" for Hypoprothrombinemia, Warfarin anticoagulation, Vitamin K-dependent clotting factors deficiency (VKCFD).
  • Also on file: Vitamin K is rated "Possibly Ineffective" for Intraventricular hemorrhage.

Vitamin K is effective for treating vitamin K deficiency states, including low prothrombin time (a blood-clotting measure), vitamin K-dependent clotting factor deficiency, and hemorrhagic disease. It's also rated possibly effective for osteoporosis, though the evidence isn't as strong.

If you're taking this for bone health specifically, the data suggests a potential benefit, but talk it over with your doctor to see if it's the right choice for you.

The evidence, ingredient by ingredient Vitamin K

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, vitamin K is generally well tolerated in healthy people. The most common side effects are mild — nausea, diarrhea, stomach upset, and abdominal pain — and they're infrequent.

The data does note that very serious reactions (like anaphylaxis) can happen if vitamin K is given by injection, but that doesn't apply to this oral liquid. Vitamin K is rated likely safe during pregnancy and breastfeeding, so you don't need to avoid it on those grounds alone.

Side effects, ingredient by ingredient Vitamin K

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin K.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you're on warfarin (Coumadin) or any other blood thinner (anticoagulant). Vitamin K can reduce how well these drugs work, which is a Major safety concern.

No other medication interactions are documented in our data for the ingredients we hold.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Bio-K-Mulsion can help if you have a vitamin K deficiency or are looking to support bone health, and it's generally well tolerated by mouth. If you take any blood thinner — especially warfarin — you must check with your doctor or pharmacist before starting.

Even if you're not on a blood thinner, confirm with your own healthcare provider that this supplement is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bio-K-Mulsion, straight from the product label.

Brand Biotics Research Corporation
Net contents 1 fl. Oz.
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 21511
Product type Vitamin
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bio-K-Mulsion by Biotics Research Corporation, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
1 Drop(s)
IngredientAmount% DV
Vitamin K500 mcg625%

Other ingredients: Water, Gum Arabic, Sesame Oil

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

(C) Copyright 2009

Bio-K-Mulsion(TM) is an oil-in-water emulsion.

General Statements

Lot Number: 34627A Exp. Date: OCT 11

Sealed with an imprinted safety seal for your protection.

SEALED FOR YOUR PROTECTION

Vitamin K oil has been dispersed into microscopic particles to aid absorption and assimilation.

Suggested/Recommended/Usage/Directions

RECOMMENDATION: One (1) drop each day as a dietary supplement or as otherwise directed by a healthcare professional.

Precautions

Caution: Those taking warfarin should avoid supplementation with Vitamin K unless specifically recommended and monitored by their physician. Pregnant and nursing mothers should avoid supplemental intakes higher that the RDA (65 mcg) unless specifically recommended and monitored by their physician.

KEEP OUT OF REACH OF CHILDREN

Storage

Store in a cool, dry area.

General

Rev. 9/09

FDA Statement of Identity

Dietary Supplement

Formula

(Emulsified Vitamin K)

See for yourself

Bio-K-Mulsion by Biotics Research Corporation label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Bio-K-Mulsion by Biotics Research Corporation

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Amounts shown are per serving.

Vitamin K

Interacts with
2 drugs
500 mcg per serving Form: Vitamin K1

Vitamin K is an essential nutrient your body needs for normal blood clotting and to support healthy bones. Most people get enough from food, but suppl...

Vitamin K monograph & interactions

Other (inactive) ingredients: Water, Gum Arabic, Sesame Oil. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bio-K-Mulsion by Biotics Research Corporation Drug Interactions

Want to check YOUR meds against Bio-K-Mulsion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2Drugs
2 Major

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Bio-K-Mulsion with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin K1 drug type · 2 drugs

Warfarin (Coumadin)

Vitamin K can antagonize and reverse the therapeutic effects of warfarin.
Vitamin K antagonizes the effects of warfarin. Excessive vitamin K intake, either from supplements or from changes in the diet, can reduce the anticoagulant effect of warfarin.

Likelihood Likely Evidence C
The maker

Brand information

Manufacturer and brand details for Bio-K-Mulsion, from the product label.

Biotics Research Corporation

See all Biotics Research Corporation products
Name
BIOTICS RESEARCH CORP.
City
Rosenberg
State
Texas
Phone Number
(281) 344-0909
Pharmacist Counseling Corner

Bio-K-Mulsion by Biotics Research Corporation: Common Questions

Does Bio-K-Mulsion by Biotics Research Corporation interact with any medications?
Yes. Based on its ingredients, Bio-K-Mulsion has a known interaction with 2 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bio-K-Mulsion contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Bio-K-Mulsion if I'm on warfarin?
No — not without checking with your doctor first. Vitamin K directly counteracts warfarin's blood-thinning effect, and even small doses from a supplement can interfere with your treatment. Your doctor may need to adjust your warfarin dose or monitor you more closely.
What are the side effects?
Taken by mouth, vitamin K is usually well tolerated. The most common side effects are mild and gastrointestinal: nausea, diarrhea, stomach upset, and abdominal pain. Serious reactions are very rare with oral supplements.
Is vitamin K safe during pregnancy and breastfeeding?
Yes — vitamin K is rated likely safe during both pregnancy and breastfeeding. That said, any supplement choice during pregnancy or nursing is worth discussing with your doctor or midwife to make sure it fits your individual needs.
What does vitamin K actually do?
Vitamin K is essential for blood clotting — your body uses it to make the proteins that stop bleeding when you're injured. It also plays a role in bone health. This supplement is effective for treating vitamin K deficiency and related clotting disorders.
Will this help my osteoporosis?
Vitamin K is rated possibly effective for osteoporosis, meaning there's some evidence it may help, but the data isn't as strong as for its clotting uses. Talk with your doctor about whether it makes sense as part of your bone health plan.
What else is in this liquid besides vitamin K?
The inactive ingredients are water, gum arabic (a natural thickener), and sesame oil. These are just carriers and fillers — the active ingredient is vitamin K.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bio-K-Mulsion is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bio-K-Mulsion label
Sources

Sources & How We Checked

Bio-K-Mulsion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin K 11 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Ann Intern Med. 2009;150(5):293-300. PubMed
  4. Dietary vitamin K guidance: an effective strategy for stable control of oral anticoagulation? Nutr Rev. 2010;68(3):178-81. PubMed
  5. Kim JS, Nafziger AN, Gaedigk A, et al. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul;41(7):715-22. PubMed
  6. Riegert-Johnson, D. L. and Volcheck, G. W. The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. Ann.Allergy Asthma Immunol. 2002;89(4):400-406. PubMed
  7. Dezee, K. J., Shimeall, W. T., Douglas, K. M., Shumway, N. M., and O'malley, P. G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch.Intern.Med. 2-27-2006;166(4):391-397. DOI
  8. Dentali, F., Ageno, W., and Crowther, M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J.Thromb.Haemost. 2006;4(9):1853-1863. PubMed
  9. Caluwé R, Vandecasteele S, Van Vlem B, Vermeer C, De Vriese AS. Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. Nephrol Dial Transplant. 2014;29(7):1385-90.
  10. Huang ZB, Wan SL, Lu YJ, Ning L, Liu C, Fan SW. Does vitamin K2 play a role in the prevention and treatment of osteoporosis for postmenopausal women: a meta-analysis of randomized controlled trials. Osteoporos Int. 2015;26(3):1175-86. PubMed
  11. Hunnali CR, Devi U, Kitchanan S, Sethuraman G. Three Different Regimens for Vitamin K Birth Prophylaxis in Infants Born Preterm: A Randomized Clinical Trial. J Pediatr 2023;255:98-104. PubMed

See these in context on the Vitamin K monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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