Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

BioCell Collagen Ingredients & Drug Interactions

by OL Olympian Labs

Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

BioCell Collagen is a dietary supplement by OL Olympian Labs with 3 active ingredients. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chondroitin Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of BioCell Collagen by OL Olympian Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “BioCell Collagen” is listed as a grouped ingredient — the label gives one combined amount (1.50 Gram(s)) without saying how much of each component you get.

BioCell Collagen contains 3 active ingredients: Hyaluronic Acid, Chondroitin Sulfate, and Chicken Collagen Type II (hydrolyzed). Hyaluronic Acid is a compound your body naturally makes that helps keep skin and joints hydrated.

Chondroitin Sulfate is a building block found in cartilage that may support joint structure and skin health. The product also includes several inactive ingredients — gelatin, rice flour, cellulose, ascorbyl palmitate, and silicon dioxide — which are binders and capsule materials.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Reduce fine lines, improve skin hydration, support joint comfort.
  • We looked for evidence on: Aging skin, Osteoarthritis, Wound healing, Dry eye, Skin elasticity, Joint mobility — and 1 related terms.
  • The strongest evidence on file: Chondroitin Sulfate is rated "Possibly Effective" for Osteoarthritis (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Possibly Effective" for Dry eye.
  • Also on file: Chondroitin Sulfate is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Dry eye.

The evidence for this product's ingredients is mixed. Hyaluronic Acid shows possibly effective evidence for dry eye and venous leg ulcers (slow-healing wounds in the legs), but for aging skin and allergies, the evidence isn't established enough to rate.

Chondroitin Sulfate is possibly effective for cataracts and osteoarthritis, though again, for aging skin, bone density, cholesterol, and precancerous growths in the colon, the evidence is insufficient. We don't have effectiveness data on file for the Chicken Collagen Type II component.

The evidence, ingredient by ingredient Hyaluronic Acid Chondroitin Sulfate

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hyaluronic Acid and Chondroitin Sulfate are generally well tolerated when taken by mouth, though the safety facts note that long-term safety of oral supplements isn't fully studied. Common side effects from chondroitin can include stomach pain, bloating, constipation, diarrhea, heartburn, and nausea.

Rare serious effects like liver damage have been reported, and some people taking chondroitin-glucosamine combinations have experienced skin reactions, swelling, or rash. The safety facts specifically advise against chondroitin during pregnancy and breastfeeding due to insufficient safety data.

Side effects, ingredient by ingredient Hyaluronic Acid Chondroitin Sulfate

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Chondroitin Sulfate.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or other blood thinners, double-check with your pharmacist before starting — Chondroitin Sulfate may increase the drug's effect and your bleeding risk. For any other prescription medications, use the checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're dealing with dry eyes or osteoarthritis, this product might be worth a try based on the evidence for its ingredients. If you take warfarin or any other blood thinner, check with us first — chondroitin can interfere.

Pregnancy or breastfeeding? Talk to your pharmacist about whether this is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BioCell Collagen, straight from the product label.

Brand OL Olympian Labs
Barcode (UPC) 710013030498
Net contents 300 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 326650
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BioCell Collagen by OL Olympian Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
100
UPC/BARCODE
710013030498
IngredientAmount% DV
Hyaluronic Acid150 mg--
Chondroitin Sulfate300 mg--
BioCell Collagen1.5 Gram(s)--
Chicken Collagen Type II, Hydrolyzed900 mg--

Other ingredients: Gelatin, Rice Flour, Cellulose, Ascorbyl Palmitate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Olympian Labs, Inc. products are made with the highest quality ingredients and manufactured according to current Good Manufacturing Practice (cGMP).

Clinically tested Advanced formula Clinically shown to: Reduce the appearance of fine lines & wrinkles Improve skin hydration & elasticity Support joint comfort & mobility

Non GMO Gluten free Allergen free

No: Milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, or soybeans.

Made in USA

We do not use ingredients that were produced using modern biotechnology

Precautions

Caution: If you are pregnant or nursing, have a medical condition, or are taking medication, consult your healthcare professional before using this or any other nutritional supplement.

Discontinue use if allergic reaction occurs.

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take three (3) capsules daily, preferably on an empty stomach, or as directed by a healthcare professional.

Brand IP Statement(s)

BioCell Collagen is a registered trademark of BioCell Technology LLC, Newport Beach, California USA (US Patents 6,025,327; 6,323,319; 6,780,841; 7,091,180; 7,799,348 other US and foreign patents pending)

Formula

BioCell Collagen To view clinical studies visit: BioCellCollagen.com

See for yourself

BioCell Collagen by OL Olympian Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in BioCell Collagen by OL Olympian Labs

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

BioCell Collagen

1.5 Gram(s) per serving

Other (inactive) ingredients: Gelatin, Rice Flour, Cellulose, Ascorbyl Palmitate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

BioCell Collagen by OL Olympian Labs Drug Interactions

Want to check YOUR meds against BioCell Collagen?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2Drugs
2 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in BioCell Collagen with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chondroitin Sulfate1 drug type · 2 drugs

Warfarin (Coumadin)

Taking chondroitin in combination with glucosamine might increase the anticoagulant effects of warfarin. However, the effect of chondroitin alone is unclear.
There have been multiple reports of increased international normalized ratio (INR) in patients taking warfarin with glucosamine, with or without chondroitin. The lack of reports with chondroitin alone seem to suggest that the interactions occurring in these reports may have been due to glucosamine. In two individual case reports, glucosamine/chondroitin combinations were associated with a significant increase in INR in patients previously stabilized on warfarin. Additionally, 20 voluntary case reports to the US Food & Drug Administration (FDA) have linked glucosamine plus chondroitin with increased INR, bruising, and bleeding in patients who were also taking warfarin. There have also been 20 additional case reports to the World Health Organization (WHO) that link glucosamine alone, without chondroitin, to increased INR in patients taking warfarin.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for BioCell Collagen, from the product label.

OL Olympian Labs

See all OL Olympian Labs products
Name
Olympian Labs, Inc.
City
Phoenix
State
AZ
ZipCode
85027
Phone Number
1.800.473.5883
Web Address
www.olympianlabs.com
Pharmacist Counseling Corner

BioCell Collagen by OL Olympian Labs: Common Questions

Does BioCell Collagen by OL Olympian Labs interact with any medications?
Yes. Based on its ingredients, BioCell Collagen has a known interaction with 2 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BioCell Collagen contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my joint pain or arthritis?
Chondroitin Sulfate in this product is possibly effective for osteoarthritis. The evidence is real but not overwhelming, so results vary person to person. Your best bet is to try it and see how you feel, and chat with your pharmacist if you're not seeing a difference after a reasonable time.
What are the side effects?
Most people tolerate this well. The main side effects from chondroitin are mild stomach issues — bloating, constipation, diarrhea, heartburn, or nausea. Skin reactions like rash or swelling are uncommon. Serious effects are rare, but liver damage has been reported in very few cases.
Can I take this while pregnant or breastfeeding?
The safety data advises against chondroitin during pregnancy and breastfeeding because there isn't enough information to know it's safe. Talk to your doctor or pharmacist — they can weigh the pros and cons for your specific situation.
What is Hyaluronic Acid doing in here?
Hyaluronic Acid is a natural compound that holds water and keeps skin and tissues hydrated. It's possibly effective for dry eye and certain wound healing, though for general anti-aging skin benefits, the evidence isn't strong enough to rate.
Is this product safe for long-term use?
The individual ingredients are generally well tolerated when taken by mouth, but the facts note that the long-term safety of supplements isn't fully studied. If you're planning to use it long-term, that's a good conversation to have with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BioCell Collagen is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BioCell Collagen label
Sources

Sources & How We Checked

BioCell Collagen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Chondroitin Sulfate 22 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  2. Tallia AF, Cardone DA. Asthma exacerbation associated with glucosamine-chondroitin supplement. J Am Board Fam Pract 2002;15:481-4..
  3. Danao-Camara T. Potential side effects of treatment with glucosamine and chondroitin. Arthritis Rheum 2000;43:2853. PubMed
  4. Rozenfeld V, Crain JL, Callahan AK. Possible augmentation of warfarin effect by glucosamine-chondroitin. Am J Health Syst Pharm 2004;61:306-307. PubMed
  5. Clegg DO, Reda DJ, Harris CL, et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med 2006;354:795-808. DOI
  6. Knudsen J, Sokol GH. Potential glucosamine-warfarin interaction resulting in increased international normalized ratio: Case report and review of the literature and MedWatch database. Pharmacotherapy 2008;28:540-8. PubMed
  7. Yue QY, Strandell J, Myrberg O. Concomitant use of glucosamine potentiates the effect of warfarin. Jan 2006. Drug Safety 29(10):911-1010. DOI
  8. Nordling, J. and van, Ophoven A. Intravesical glycosaminoglycan replenishment with chondroitin sulphate in chronic forms of cystitis. A multi-national, multi-centre, prospective observational clinical trial. Arzneimittelforschung. 2008;58(7):328-335. PubMed
  9. Nickel, J. C., Egerdie, B., Downey, J., Singh, R., Skehan, A., Carr, L., and Irvine-Bird, K. A real-life multicentre clinical practice study to evaluate the efficacy and safety of intravesical chondroitin sulphate for the treatment of interstitial cystit
  10. Oliviero, U., Sorrentino, G. P., De Paola, P., Tranfaglia, E., D'Alessandro, A., Carifi, S., Porfido, F. A., Cerio, R., Grasso, A. M., Policicchio, D., and . Effects of the treatment with matrix on elderly people with chronic articular degeneration. Drug
  11. Crowley, D. C., Lau, F. C., Sharma, P., Evans, M., Guthrie, N., Bagchi, M., Bagchi, D., Dey, D. K., and Raychaudhuri, S. P. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int.J.Med.Sc PubMed
  12. Nickel, J. C., Egerdie, R. B., Steinhoff, G., Palmer, B., and Hanno, P. A multicenter, randomized, double-blind, parallel group pilot evaluation of the efficacy and safety of intravesical sodium chondroitin sulfate versus vehicle control in patients with
  13. Sawitzke, A. D., Shi, H., Finco, M. F., Dunlop, D. D., Harris, C. L., Singer, N. G., Bradley, J. D., Silver, D., Jackson, C. G., Lane, N. E., Oddis, C. V., Wolfe, F., Lisse, J., Furst, D. E., Bingham, C. O., Reda, D. J., Moskowitz, R. W., Williams, H. J.
  14. Wildi, L. M., Raynauld, J. P., Martel-Pelletier, J., Beaulieu, A., Bessette, L., Morin, F., Abram, F., Dorais, M., and Pelletier, J. P. Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starti
  15. Pavelka and et al. Double-blind, dose effect study of oral cs 4 & 6 1200mg, 800mg, 200mg against placebo in the treatment of femorotibial osteoarthritis. Wular Rheumatol Liter 1998;27(suppl 2):63.
  16. Cerda C, Bruguera M, Parés A. Hepatotoxicity associated with glucosamine and chondroitin sulfate in patients with chronic liver disease. World J Gastroenterol 2013;19(32):5381-4. PubMed
  17. von Felden J, Montani M, Kessebohm K, Stickel F. Drug-induced acute liver injury mimicking autoimmune hepatitis after intake of dietary supplements containing glucosamine and chondroitin sulfate. Int J Clin Pharmacol Ther 2013;51(3):219-23. PubMed
  18. Provenza JR, Shinjo SK, Silva JM, Peron CR, Rocha FA. Combined glucosamine and chondroitin sulfate, once or three times daily, provides clinically relevant analgesia in knee osteoarthritis. Clin Rheumatol 2015;34:1455-62. PubMed
  19. Ossendza RA, Grandval P, Chinoune F, Rocher F, Chapel F, Bernardini D. [Acute cholestatic hepatitis due to glucosamine forte]. Gastroenterol Clin Biol. 2007 Apr;31(4):449-50.
  20. Greenlee H, Crew KD, Shao T, Kranwinkel G, Kalinsky K, Maurer M, Brafman L, Insel B, Tsai WY, Hershman DL. Phase II study of glucosamine with chondroitin on aromatase inhibitor-associated joint symptoms in women with breast cancer. Support Care Cancer 201 PubMed
  21. Chu EC, Huang KHK, Cheung G, Ng G, Lin A. Delayed Skin Allergy to Glucosamine Chondroitin Supplement. Cureus 2023;15(3):e36310. PubMed
  22. Lila AM, Alekseeva LI, Baranov AA, et al. Chondroitin sulfate and glucosamine combination in patients with knee and hip osteoarthritis: A long-term observational study in Russia. World J Orthop 2023;14(6):443-457. PubMed

See these in context on the Chondroitin Sulfate monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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