No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 2 of 8 ingredients. Check your meds →
Dietary supplement

BioCore Enhanced Enzymes Ingredients & Drug Interactions

by Protocol For Life Balance

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

BioCore Enhanced Enzymes is a dietary supplement by Protocol For Life Balance with 8 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of BioCore Enhanced Enzymes by Protocol For Life Balance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 8 active ingredients.
  • “BioCore Optimum” is listed as a grouped ingredient — the label gives one combined amount (200 mg) without saying how much of each component you get.

BioCore Enhanced Enzymes is a blend of eight digestive enzymes. The ones we have data for are protease (which breaks down proteins), lipase (which breaks down fats), and several carbohydrate-digesting enzymes including amylase, glucoamylase, invertase, diastase, and alpha-galactosidase.

The capsule also contains inactive ingredients: rice bran, cellulose, rice dextrin, and silica.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: aid in digestion of most foods.
  • We looked for evidence on: Dyspepsia, Malabsorption, Pancreatic insufficiency, Food intolerance.
  • The closest evidence on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia (Natural Medicines).

The evidence we hold is thin here. For lipase, the data shows insufficient reliable evidence to rate how well it works for inflammatory bowel disease, indigestion, or prematurity.

We don't have effectiveness ratings for protease or the other carbohydrate enzymes in this product. That said, digestive enzyme blends are marketed to support digestion — but the research backing this specific product's claims isn't established in our data.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Protease and lipase are generally well tolerated by most adults, though some people report digestive upset or allergic reactions. Protease has been linked to rare allergic responses in people with occupational exposure to airborne enzymes; reactions included allergic rhinitis and asthma, though these cases were not from oral supplements.

For pregnancy, safety data on protease has not been established, so it's best avoided unless your doctor prescribes it. Lipase safety in pregnancy is also not well studied — use only if your doctor advises it.

During breastfeeding, there is little safety data for either ingredient, so check with your healthcare provider first before using this product if you're nursing.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases) Lipase

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 2 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, confirm with your pharmacist or doctor before combining this product with any prescription or regular over-the-counter medication.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

This product may appeal to anyone looking for digestive enzyme support, but the evidence for how well it actually works isn't solid yet. If you're pregnant, nursing, or have a serious digestive condition, talk it over with your doctor or pharmacist before starting.

Always run your medications through the checker on this page to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BioCore Enhanced Enzymes, straight from the product label.

Brand Protocol For Life Balance
Barcode (UPC) 707359129580
Net contents 90 Veg Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2017
DSLD ID 73220
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BioCore Enhanced Enzymes by Protocol For Life Balance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg Capsule(s)
Maximum serving Sizes:
2 Veg Capsule(s)
Servings per container
45
UPC/BARCODE
707359129580
IngredientAmount% DV
Amylase0 NP--
Protease0 NP--
Protease0 NP--
Glucoamylase0 NP--
Invertase0 NP--
Diastase0 NP--
Lipase0 NP--
Alpha-Galactosidase30 mg--
BioCore Optimum200 mg--

Other ingredients: Rice Bran, Cellulose, Rice Dextrin, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1 to 2 capsules before each meal, or as directed by your healthcare practitioner.

General Statements

How It Works: Digestive enzymes are essential to the body's absorption and full use of food. The capacity of the body to make enzymes diminishes with age in some individuals, and therefore the efficiency of digestion may decline.

Natural color variation may occur in this product.

Scientifically tested enzymes

~ Maximum food utilization* ~ Also helps bean and cabbage digestion*

Brand IP Statement(s)

BioCore Enhanced Enzymes offers a blend of fungal-derived enzymes that will aid in the digestion of most foods, including beans and cruciferous vegetables.* The vegetarian enzymes in BioCore Enhanced Enzymes have been tested in a controlled laboratory study using a digestive model for their activity throughout the entire pH range of the digestive system and have been shown not to be degraded by acid in the stomach.*

BioCore Optimum is a trademark of National Enzyme Company.

Precautions

Cautions/Interactions: Galactosemics should consult their healthcare practitioner before use.

Do not eat freshness packet, Keep in bottle.

Not manufactured with wheat, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

General

Code P2958 V6

FDA Statement of Identity

A Dietary Supplement

Formulation

Vegetarian/Vegan

Not manufactured with wheat, soy, milk, egg, fish, shellfish or tree nut ingredients.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

BioCore Enhanced Enzymes by Protocol For Life Balance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in BioCore Enhanced Enzymes by Protocol For Life Balance

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Alpha-Galactosidase

30 mg per serving Form: Aspergillus niger

BioCore Optimum

200 mg per serving

Other (inactive) ingredients: Rice Bran, Cellulose, Rice Dextrin, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

BioCore Enhanced Enzymes by Protocol For Life Balance Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in BioCore Enhanced Enzymes. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for BioCore Enhanced Enzymes, from the product label.

Protocol For Life Balance

See all Protocol For Life Balance products
Name
Protocol For Life Balance
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
www.protocolforlife.com
Pharmacist Counseling Corner

BioCore Enhanced Enzymes by Protocol For Life Balance: Common Questions

Does BioCore Enhanced Enzymes by Protocol For Life Balance interact with any medications?
We do not currently list a known interaction for the mapped ingredients in BioCore Enhanced Enzymes. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
BioCore Enhanced Enzymes contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is protease safe to take while I'm pregnant?
Safety data on protease during pregnancy has not been established, so it's best avoided unless your doctor prescribes it. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant or planning to be.
Can I take this while breastfeeding?
There is little safety data for protease and lipase during breastfeeding. Check with your healthcare provider first to see if it's okay for you.
Does protease cause allergic reactions?
Most people tolerate it well, but allergic reactions are possible. In rare cases, occupational airborne exposure to proteolytic enzymes has caused allergic rhinitis and asthma — though these were not from oral supplements. Digestive upset is also reported occasionally.
What does each enzyme in this blend do?
Protease breaks down proteins, lipase breaks down fats, and the others (amylase, glucoamylase, invertase, and diastase) break down different carbohydrates. Alpha-galactosidase helps with certain complex carbohydrates that can cause gas.
Is there good evidence this product works for digestion?
The evidence we hold is insufficient — we don't have reliable data showing how well lipase works for indigestion or other digestive issues, and we have no effectiveness ratings for the other enzymes in this blend.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BioCore Enhanced Enzymes is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BioCore Enhanced Enzymes label
Sources

Sources & How We Checked

BioCore Enhanced Enzymes's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring